The atypical α2β2 IGF receptor expressed in inducible c2.7 myoblasts is derived from post-translational modifications of the mouse IGF-I receptor

Growth Hormone and IGF Research

Volumn 18, Issue 5, 2008, Pages 412-423

  Navarro, Magali ^a   Joulia, Dominique ^b   Fedon, Yann ^a   Levin, Jonathan ^a   Barenton, Bruno ^c   Bernardi, Henri ^a  

^a University of Montpellier   (France)

^b CENTRE HOSPITALIER UNIVERSITAIRE DE TREICHVILLE   (Côte d’Ivoire)

^c INSERM   (France)

Author keywords

IGF I; IGF I receptor; IGF II; IGF II M6P receptor; Insulin receptor (IR); Myoblast; Myoblastic differentiation

Indexed keywords

ALPHA2BETA2 SOMATOMEDIN RECEPTOR; COMPLEMENTARY DNA; INSULIN RECEPTOR; MYOGENIC FACTOR; SOMATOMEDIN C RECEPTOR; SOMATOMEDIN RECEPTOR; SOMATOMEDIN B;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; BIOCHEMISTRY; CANCER CELL; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO CELL; GENE OVEREXPRESSION; GENE SEQUENCE; GENETIC POLYMORPHISM; GENETIC SCREENING; HUMAN; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; LIGAND BINDING; MOLECULAR CLONING; MOUSE; MYOBLAST; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STRUCTURE; QUANTITATIVE ANALYSIS; RECEPTOR AFFINITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; CELL LINE; GENETICS; METABOLISM; PHOSPHORYLATION;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; DNA, COMPLEMENTARY; INSULIN-LIKE GROWTH FACTOR II; MICE; MYOBLASTS; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTOR, IGF TYPE 1; RECEPTOR, INSULIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 46849107156     PISSN: 10966374     EISSN: 15322238     Source Type: Journal    
DOI: 10.1016/j.ghir.2008.03.001     Document Type: Article

References (53)

1. Jones J.I., and Clemmons D.R. Insulin-like growth factors and their binding proteins: biological actions. Endocr. Rev. 16 (1995) 3-34
2. Cohick W.S., and Clemmons D.R. The insulin-like growth factors. Annu. Rev. Physiol. 55 (1993) 131-153
3. Sara V.R., and Hall K. Insulin-like growth factors and their binding proteins. Physiol. Rev. 70 (1990) 591-614
4. Montarras D., Aurade F., Johnson T., J I.I., Gros F., and Pinset C. Autonomous differentiation in the mouse myogenic cell line, C2, involves a mutual positive control between insulin-like growth factor II and MyoD, operating as early as at the myoblast stage. J. Cell Sci. 109 Pt 3 (1996) 551-560
5. DeChiara T.M., Efstratiadis A., and Robertson E.J. A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature 345 (1990) 78-80
6. Powell-Braxton L., Hollingshead P., Warburton C., Dowd M., Pitts-Meek S., Dalton D., Gillett N., and Stewart T.A. IGF-I is required for normal embryonic growth in mice. Genes Dev. 7 (1993) 2609-2617
7. Florini J.R. Hormonal control of muscle growth. Muscle Nerve 10 (1987) 577-598
8. Tai Y.T., Podar K., Catley L., Tseng Y.H., Akiyama M., Shringarpure R., Burger R., Hideshima T., Chauhan D., Mitsiades N., Richardson P., Munshi N.C., Kahn C.R., Mitsiades C., and Anderson K.C. Insulin-like growth factor-1 induces adhesion and migration in human multiple myeloma cells via activation of beta1-integrin and phosphatidylinositol 3′-kinase/AKT signaling. Cancer Res. 63 (2003) 5850-5858
9. Barbieri M., Bonafe M., Franceschi C., and Paolisso G. Insulin/IGF-I-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans. Am. J. Physiol. Endocrinol. Metab. 285 (2003) E1064-E1071
10. Khandwala H.M., McCutcheon I.E., Flyvbjerg A., and Friend K.E. The effects of insulin-like growth factors on tumorigenesis and neoplastic growth. Endocr. Rev. 21 (2000) 215-244
11. Rodriguez-Tarduchy G., Collins M.K., Garcia I., and Lopez-Rivas A. Insulin-like growth factor-I inhibits apoptosis in IL-3-dependent hemopoietic cells. J. Immunol. 149 (1992) 535-540
12. Han V.K., Lund P.K., Lee D.C., and D'Ercole A.J. Expression of somatomedin/insulin-like growth factor messenger ribonucleic acids in the human fetus: identification, characterization, and tissue distribution. J. Clin. Endocrinol. Metab. 66 (1988) 422-429
13. Roberts Jr. C.T., Lasky S.R., Lowe Jr. W.L., Seaman W.T., and LeRoith D. Molecular cloning of rat insulin-like growth factor I complementary deoxyribonucleic acids: differential messenger ribonucleic acid processing and regulation by growth hormone in extrahepatic tissues. Mol. Endocrinol. 1 (1987) 243-248
14. Conover C.A., Rosenfeld R.G., and Hintz R.L. Insulin-like growth factor II binding and action in human fetal fibroblasts. J. Cell Physiol. 133 (1987) 560-566
15. Rechler M.M., and Nissley S.P. The nature and regulation of the receptors for insulin-like growth factors. Annu. Rev. Physiol. 47 (1985) 425-442
16. King G.L., Kahn C.R., Rechler M.M., and Nissley S.P. Direct demonstration of separate receptors for growth and metabolic activities of insulin and multiplication-stimulating activity (an insulin-like growth factor) using antibodies to the insulin receptor. J. Clin. Invest. 66 (1980) 130-140
17. Louvi A., Accili D., and Efstratiadis A. Growth-promoting interaction of IGF-II with the insulin receptor during mouse embryonic development. Dev. Biol. 189 (1997) 33-48
18. Kim J.J., and Dahms N.M. The cation-dependent mannose 6-phosphate receptor. Results Problems Cell Differ. 33 (2001) 39-56
19. Hwa V., Oh Y., and Rosenfeld R.G. The insulin-like growth factor-binding protein (IGFBP) superfamily. Endocr. Rev. 20 (1999) 761-787
20. Blakesley V.A., Stannard B.S., Kalebic T., Helman L.J., and LeRoith D. Role of the IGF-I receptor in mutagenesis and tumor promotion. J. Endocrinol. 152 (1997) 339-344
21. Baker J., Liu J.P., Robertson E.J., and Efstratiadis A. Role of insulin-like growth factors in embryonic and postnatal growth. Cell 75 (1993) 73-82
22. Soos M.A., Field C.E., and Siddle K. Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity. Biochem. J. 290 Pt 2 (1993) 419-426
23. Stewart C.E., and Rotwein P. Growth, differentiation, and survival: multiple physiological functions for insulin-like growth factors. Physiol. Rev. 76 (1996) 1005-1026
24. Frasca F., Pandini G., Scalia P., Sciacca L., Mineo R., Costantino A., Goldfine I.D., Belfiore A., and Vigneri R. Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells. Mol. Cell Biol. 19 (1999) 3278-3288
25. Pandini G., Medico E., Conte E., Sciacca L., Vigneri R., and Belfiore A. Differential gene expression induced by insulin and insulin-like growth factor-II through the insulin receptor isoform A. J. Biol. Chem. 278 (2003) 42178-42189
26. Sciacca L., Costantino A., Pandini G., Mineo R., Frasca F., Scalia P., Sbraccia P., Goldfine I.D., Vigneri R., and Belfiore A. Insulin receptor activation by IGF-II in breast cancers: evidence for a new autocrine/paracrine mechanism. Oncogene 18 (1999) 2471-2479
27. Denley A., Wallace J.C., Cosgrove L.J., and Forbes B.E. The insulin receptor isoform exon 11 - (IR-A) in cancer and other diseases: a review. Horm. Metab. Res. 35 (2003) 778-785
28. Alexandrides T., Moses A.C., and Smith R.J. Developmental expression of receptors for insulin, insulin-like growth factor I (IGF-I), and IGF-II in rat skeletal muscle. Endocrinology 124 (1989) 1064-1076
29. Misra P., Hintz R.L., and Rosenfeld R.G. Structural and immunological characterization of insulin-like growth factor II binding to IM-9 cells. J. Clin. Endocrinol. Metab. 63 (1986) 1400-1405
30. Garofalo R.S., and Barenton B. Functional and immunological distinction between insulin-like growth factor I receptor subtypes in KB cells. J. Biol. Chem. 267 (1992) 11470-11475
31. Yee D., Lebovic G.S., Marcus R.R., and Rosen N. Identification of an alternate type I insulin-like growth factor receptor beta subunit mRNA transcript. J. Biol. Chem. 264 (1989) 21439-21441
32. Ota A., Wilson G.L., and Leroith D. Insulin-like growth factor I receptors on mouse neuroblastoma cells. Two beta subunits are derived from differences in glycosylation. Eur. J. Biochem. 174 (1988) 521-530
33. Kellerer M., Obermaier-Kusser B., Ermel B., Wallner U., Haring H.U., and Petrides P.E. An altered IGF-I receptor is present in human leukemic cells. J. Biol. Chem. 265 (1990) 9340-9345
34. Moxham C.P., Duronio V., and Jacobs S. Insulin-like growth factor I receptor beta-subunit heterogeneity. Evidence for hybrid tetramers composed of insulin-like growth factor I and insulin receptor heterodimers. J. Biol. Chem. 264 (1989) 13238-13244
35. Pandini G., Vigneri R., Costantino A., Frasca F., Ippolito A., Fujita-Yamaguchi Y., Siddle K., Goldfine I.D., and Belfiore A. Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: evidence for a second mechanism of IGF-I signaling. Clin. Cancer Res. 5 (1999) 1935-1944
36. Rosenthal S.M., Brunetti A., Brown E.J., Mamula P.W., and Goldfine I.D. Regulation of insulin-like growth factor (IGF) I receptor expression during muscle cell differentiation. Potential autocrine role of IGF-II. J. Clin. Invest. 87 (1991) 1212-1219
37. Florini J.R., Magri K.A., Ewton D.Z., James P.L., Grindstaff K., and Rotwein P.S. "Spontaneous" differentiation of skeletal myoblasts is dependent upon autocrine secretion of insulin-like growth factor-II. J. Biol. Chem. 266 (1991) 15917-15923
38. Domeyne A., Pinset C., Montarras D., Garandel V., Rosenfeld R.G., and Barenton B. Preferential binding of insulin-like growth factor-II (IGF-II) to a putative alpha 2 beta 2 IGF-II receptor type in C2 myoblasts. Eur. J. Biochem. 208 (1992) 273-279
39. Barenton B., Domeyne A., Garandel V., and Garofalo R.S. A developmentally regulated form of insulin-like growth factor receptor beta-subunit in C2 myoblasts exhibiting altered requirements for differentiation. Endocrinology 133 (1993) 651-660
40. Yaffe D., and Saxel O. Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle. Nature 270 (1977) 725-727
41. Pinset C., Montarras D., Chenevert J., Minty A., Barton P., Laurent C., and Gros F. Control of myogenesis in the mouse myogenic C2 cell line by medium composition and by insulin: characterization of permissive and inducible C2 myoblasts. Differentiation 38 (1988) 28-34
42. Garofalo R.S., and Rosen O.M. Insulin and insulin-like growth factor 1 (IGF-1) receptors during central nervous system development: expression of two immunologically distinct IGF-1 receptor beta subunits. Mol. Cell Biol. 9 (1989) 2806-2817
43. Navarro M., Barenton B., Garandel V., Schnekenburger J., and Bernardi H. Insulin-like growth factor I (IGF-I) receptor overexpression abolishes the IGF requirement for differentiation and induces a ligand-dependent transformed phenotype in C2 inducible myoblasts. Endocrinology 138 (1997) 5210-5219
44. Keyhanfar M., Booker G.W., Whittaker J., Wallace J.C., and Forbes B.E. Precise mapping of an IGF-I binding site on the IGF-1R. Biochem. J. (2006)
45. Sorensen H., Whittaker L., Hinrichsen J., Groth A., and Whittaker J. Mapping of the insulin-like growth factor II binding site of the Type I insulin-like growth factor receptor by alanine scanning mutagenesis. FEBS Lett. 565 (2004) 19-22
46. Montarras D., Pinset C., Chelly J., Kahn A., and Gros F. Expression of MyoD1 coincides with terminal differentiation in determined but inducible muscle cells. EMBO J. 8 (1989) 2203-2207
47. Montarras D., Chelly J., Bober E., Arnold H., Ott M.O., Gros F., and Pinset C. Developmental patterns in the expression of Myf5, MyoD, myogenin, and MRF4 during myogenesis. New Biol. 3 (1991) 592-600
48. Jonas H.A., Newman J.D., and Harrison L.C. An atypical insulin receptor with high affinity for insulin-like growth factors copurified with placental insulin receptors. Proc. Natl. Acad. Sci. U.S.A. 83 (1986) 4124-4128
49. Hintz R.L., Thorsson A.V., Enberg G., and Hall K. IGF-II binding on human lymphoid cells: demonstration of a common high affinity receptor for insulin like peptides. Biochem. Biophys. Res. Commun. 118 (1984) 774-782
50. Liu J.P., Baker J., Perkins A.S., Robertson E.J., and Efstratiadis A. Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell 75 (1993) 59-72
51. Denley A., Bonython E.R., Booker G.W., Cosgrove L.J., Forbes B.E., Ward C.W., and Wallace J.C. Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus isoform of the IR. Mol. Endocrinol. 18 (2004) 2502-2512
52. Leconte I., Auzan C., Debant A., Rossi B., and Clauser E. N-linked oligosaccharide chains of the insulin receptor beta subunit are essential for transmembrane signaling. Journal Biol. Chem. 267 (1992) 17415-17423
53. Leconte I., Carpentier J.L., and Clauser E. The functions of the human insulin receptor are affected in different ways by mutation of each of the four N-glycosylation sites in the beta subunit. J. Biol. Chem. 269 (1994) 18062-18071