Mapping of the insulin-like growth factor II binding site of the Type I insulin-like growth factor receptor by alanine scanning mutagenesis

FEBS Letters

Volumn 565, Issue 1-3, 2004, Pages 19-22

  Sørensen, Heidi ^a   Whittaker, Linda ^a   Hinrichsen, Jane ^a   Groth, Andreas ^a   Whittaker, Jonathan ^a,b  

^a HAGEDORN RESEARCH INSTITUTE   (Denmark)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

125I Tyr31 IGF I, insulin like growth factor I radio iodinated on Tyrosine 31; Affinity; Growth factor; IGF I, insulin like growth factor I; IGF II, insulin like growth factor II; Mutagenesis; Receptor

Indexed keywords

ALANINE; CYSTEINE; SOMATOMEDIN B; SOMATOMEDIN C RECEPTOR;

ALANINE SCANNING MUTAGENESIS; ALPHA CHAIN; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; LIGAND BINDING; MOLECULAR BIOLOGY; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

ALANINE; BINDING SITES; CELL LINE; CYSTEINE; DNA, COMPLEMENTARY; EPITOPES; HUMANS; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; KINETICS; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY;

EID: 2342551975     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2004.03.077     Document Type: Article

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