Characterization of mass ionizable degradation products of gliclazide by LC/ESI-MS

Journal of Liquid Chromatography and Related Technologies

Volumn 31, Issue 14, 2008, Pages 2174-2193

  Bansal, Gulshan ^a   Singh, Manjeet ^a   Jindal, K C ^b   Singh, Saranjit ^c  

^a PUNJABI UNIVERSITY   (India)

^b M/S Panacea Biotec Limited   (India)

^c NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Degradation pathway; Degradation products; Gliclazide; LC ESI MS; Mass fragmentation; Stress testing

Indexed keywords

CHEMOTHERAPY; DRUG DELIVERY; DRUG DOSAGE; ESTERS; METHANOL; ORGANIC COMPOUNDS; SOLUTIONS; SULFATE MINERALS; VEGETATION;

ACTIVE DEGRADATION PRODUCTS; DEGRADATION PRODUCTS; FRAGMENTATION PATTERNS; GLICLAZIDE (GL); HARMONISATION; INTERNATIONAL CONFERENCES; METHYL ESTERS; PYRIDAZINE; REACTION SOLUTIONS; STRESS CONDITIONS;

DEGRADATION;

4 TOLYLSULFONAMIDE; 4,4A,5,6,7,7A HEXAHYDRO 3H CYCLOPENTA[D]PYRIDAZIN 1 YL (4 TOLYLSULFONYL)CARBAMATE; GLICLAZIDE; METHYL N (4 TOLYLSULFONYL)CARBAMATE; N (4,4A,5,6,7,7A HEXAHYDRO 3H CYCLOPENTA[D]PYRIDAZINE 1 CARBONYL) 4 METHYL BENZENESULFONAMIDE;

ARTICLE; DRUG DEGRADATION; DRUG RESEARCH; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; FRAGMENTATION REACTION; LIQUID CHROMATOGRAPHY; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

EID: 46849088986     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826070802225585     Document Type: Article

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