Application of liquid chromatography-mass spectrometry(n) analyses to the characterization of novel glyburide metabolites formed in vitro

Journal of Chromatography A

Volumn 794, Issue 1-2, 1998, Pages 15-25

  Tiller, P R ^a   Land, A P ^a   Jardine, I ^a   Murphy, D M ^b   Sozio, R ^b   Ayrton, A ^b   Schaefer, W H ^b  

^a Thermo Finnigan   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Glyburide; Mass spectrometry; Pharmaceutical analysis; Sulfonylureas

Indexed keywords

DRUG METABOLITE; GLIBENCLAMIDE;

ANIMAL TISSUE; ARTICLE; CONFORMATIONAL TRANSITION; DOG; DRUG CONFORMATION; DRUG DETERMINATION; DRUG HYDROLYSIS; DRUG OXIDATION; HUMAN; HUMAN TISSUE; LIQUID CHROMATOGRAPHY; LIVER MICROSOME METABOLISM; MASS SPECTROMETRY; MONKEY; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ANALYSIS;

ANIMALS; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLYBURIDE; HUMANS; HYPOGLYCEMIC AGENTS; INDICATORS AND REAGENTS; MASS SPECTROMETRY; MICROSOMES, LIVER; RATS;

ANIMALIA; CANIS FAMILIARIS;

EID: 0032559355     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9673(97)00881-9     Document Type: Article

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