Large-scale N-terminal deletions but not point mutations stabilize β-catenin in small bowel carcinomas, suggesting divergent molecular pathways of small and large intestinal carcinogenesis

Journal of Pathology

Volumn 215, Issue 3, 2008, Pages 300-307

  Breuhahn, K ^a   Singh, S ^a   Schirmacher, P ^a   Blaker H ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

catenin; Carcinoma; Small bowel; Small intestine; Wnt wingless

Indexed keywords

BETA CATENIN;

ADENOCARCINOMA; ADULT; AGED; AMINO TERMINAL SEQUENCE; ARTICLE; CARCINOGENESIS; CELLULAR DISTRIBUTION; COLON CARCINOMA; COLON POLYPOSIS; CONTROLLED STUDY; DNA DETERMINATION; FEMALE; GENE DELETION; GENE INSERTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINE CARCINOMA; MALE; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN STABILITY; RNA ANALYSIS; RNA TRANSCRIPTION; SEQUENCE ANALYSIS; WESTERN BLOTTING;

ADENOCARCINOMA; ADENOMATOUS POLYPOSIS COLI; ADULT; AGED; AGED, 80 AND OVER; BETA CATENIN; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; CYTOPLASM; DNA MUTATIONAL ANALYSIS; DUODENAL NEOPLASMS; EXONS; FEMALE; GENES, APC; HUMANS; ILEAL NEOPLASMS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INTESTINAL NEOPLASMS; JEJUNAL NEOPLASMS; MALE; MIDDLE AGED; POINT MUTATION; SEQUENCE ANALYSIS, RNA; SEQUENCE DELETION; WNT PROTEINS;

EID: 46849086023     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2362     Document Type: Article

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