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Volumn 28, Issue 3, 2008, Pages 130-134

Thrombophilia and its impact on pregnancy

Author keywords

Abortion; Fetal loss; Pre eclampsia; Pregnancy; Stillbirth; Thrombophilia

Indexed keywords

BLOOD CLOTTING FACTOR 5 LEIDEN; HEPARIN; PHOSPHOLIPID ANTIBODY; PROTHROMBIN;

EID: 46749119889     PISSN: 07209355     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1617170     Document Type: Review
Times cited : (14)

References (58)
  • 1
    • 0033836411 scopus 로고    scopus 로고
    • Recurrent miscarriage syndrome due to blood coagulation protein/platelet defects: Prevalence, treatment and outcome results. DRW Metroplex Recurrent Miscarriage Syndrome Cooperative Group
    • Bick RL. Recurrent miscarriage syndrome due to blood coagulation protein/platelet defects: prevalence, treatment and outcome results. DRW Metroplex Recurrent Miscarriage Syndrome Cooperative Group. Clin Appl Thromb Hemost 2000; 6: 115-125.
    • (2000) Clin Appl Thromb Hemost , vol.6 , pp. 115-125
    • Bick, R.L.1
  • 2
    • 0031862017 scopus 로고    scopus 로고
    • Activated protein C sensitivity, protein C, protein S and coagulation in normal pregnancy
    • Clark P, Brennand J, Conkie JA et al. Activated protein C sensitivity, protein C, protein S and coagulation in normal pregnancy. Thromb Haemost 1998; 79: 1166-1170.
    • (1998) Thromb Haemost , vol.79 , pp. 1166-1170
    • Clark, P.1    Brennand, J.2    Conkie, J.A.3
  • 4
    • 0023038667 scopus 로고    scopus 로고
    • Comp PC, Thurnau GR, Welsh J et al. Functional and immunologic protein S levels are decreased during pregnancy. Blood 1986; 68: 881-885.
    • Comp PC, Thurnau GR, Welsh J et al. Functional and immunologic protein S levels are decreased during pregnancy. Blood 1986; 68: 881-885.
  • 5
    • 0014681379 scopus 로고
    • Fibrinolytic enzyme system and pregnancy
    • Bonnar J, McNicol GP, Douglas AS. Fibrinolytic enzyme system and pregnancy. Br Med J 1969; 3: 387-389.
    • (1969) Br Med J , vol.3 , pp. 387-389
    • Bonnar, J.1    McNicol, G.P.2    Douglas, A.S.3
  • 6
    • 0020026065 scopus 로고
    • The coagulation and fibrinolytic enzyme system in pregnancy and in the Puerperium
    • Beller FK, Ebert C. The coagulation and fibrinolytic enzyme system in pregnancy and in the Puerperium. Eur J Obstet Gynecol Reprod Biol 1982; 13: 177-197.
    • (1982) Eur J Obstet Gynecol Reprod Biol , vol.13 , pp. 177-197
    • Beller, F.K.1    Ebert, C.2
  • 8
    • 16044369784 scopus 로고    scopus 로고
    • Increased fetal loss in women with heritable thrombophilia
    • Preston FE, Rosendaal FR, Walker ID et al. Increased fetal loss in women with heritable thrombophilia. Lancet 1996; 348: 913-916.
    • (1996) Lancet , vol.348 , pp. 913-916
    • Preston, F.E.1    Rosendaal, F.R.2    Walker, I.D.3
  • 9
    • 0030064905 scopus 로고    scopus 로고
    • Second-trimester pregnancy loss is associated with activated C resistance
    • Rai R, Regan L, Hadley E et al. Second-trimester pregnancy loss is associated with activated C resistance. Br J Haematol 1996; 92: 489-490.
    • (1996) Br J Haematol , vol.92 , pp. 489-490
    • Rai, R.1    Regan, L.2    Hadley, E.3
  • 10
    • 0029874198 scopus 로고    scopus 로고
    • The risk of abortion and stillbirth in antithrombin-, protein C-, and protein S-deficient women
    • Sanson BJ, Friederich PW, Simioni P et al. The risk of abortion and stillbirth in antithrombin-, protein C-, and protein S-deficient women. Thromb Haemost 1996; 75: 387-388.
    • (1996) Thromb Haemost , vol.75 , pp. 387-388
    • Sanson, B.J.1    Friederich, P.W.2    Simioni, P.3
  • 11
    • 0033531184 scopus 로고    scopus 로고
    • Increased frequency of genetic thrombophilia in women with complications of pregnancy
    • Kupferminc MJ, Eldor A, Steinman N et al. Increased frequency of genetic thrombophilia in women with complications of pregnancy. N Engl J Med 1999; 340: 9-13.
    • (1999) N Engl J Med , vol.340 , pp. 9-13
    • Kupferminc, M.J.1    Eldor, A.2    Steinman, N.3
  • 12
    • 0031155778 scopus 로고    scopus 로고
    • Respective evaluation of the prevalence of haemostasis abnormalities in unexplained primary early recurrent miscarriages. The Nimes Obstetricians and Haematologists (NOHA) Study
    • Gris JC, Ripart-Neveu S, Maugard C et al. Respective evaluation of the prevalence of haemostasis abnormalities in unexplained primary early recurrent miscarriages. The Nimes Obstetricians and Haematologists (NOHA) Study. Thromb Haemost 1997; 77: 1096-1103.
    • (1997) Thromb Haemost , vol.77 , pp. 1096-1103
    • Gris, J.C.1    Ripart-Neveu, S.2    Maugard, C.3
  • 13
    • 0030928377 scopus 로고    scopus 로고
    • Factor V Leiden is associated with repeated and recurrent unexplained fetal losses
    • Grandone E, Margaglione M, Colaizzo D et al. Factor V Leiden is associated with repeated and recurrent unexplained fetal losses. Thromb Haemost 1997; 77: 822-824.
    • (1997) Thromb Haemost , vol.77 , pp. 822-824
    • Grandone, E.1    Margaglione, M.2    Colaizzo, D.3
  • 14
    • 0034610031 scopus 로고    scopus 로고
    • Mutations in coagulation factors in women with unexplained late fetal loss
    • Martinelli I, Taioli E, Cetin I et al. Mutations in coagulation factors in women with unexplained late fetal loss. N Engl J Med 2000; 343: 1015-1018.
    • (2000) N Engl J Med , vol.343 , pp. 1015-1018
    • Martinelli, I.1    Taioli, E.2    Cetin, I.3
  • 15
    • 0033973640 scopus 로고    scopus 로고
    • Activated protein C resistance and factor V Leiden mutation can be associated with first-as well as second-trimester recurrent pregnancy loss
    • Younis JS, Brenner B, Ohel G et al. Activated protein C resistance and factor V Leiden mutation can be associated with first-as well as second-trimester recurrent pregnancy loss. Am J Reprod Immunol 2000; 43: 31-35.
    • (2000) Am J Reprod Immunol , vol.43 , pp. 31-35
    • Younis, J.S.1    Brenner, B.2    Ohel, G.3
  • 16
    • 0034919759 scopus 로고    scopus 로고
    • Thrombophilic gene mutations and recurrent spontaneous abortion: Prothrombin mutation increases the risk in the first trimester
    • Pihusch R, Buchholz T, Lohse P et al. Thrombophilic gene mutations and recurrent spontaneous abortion: prothrombin mutation increases the risk in the first trimester. Am J Reprod Immunol 2001; 46: 124-131.
    • (2001) Am J Reprod Immunol , vol.46 , pp. 124-131
    • Pihusch, R.1    Buchholz, T.2    Lohse, P.3
  • 17
    • 0036854180 scopus 로고    scopus 로고
    • Acquired and inherited thrombophilia in women with unexplained fetal losses
    • Alonso A, Soto I, Urgelles MF et al. Acquired and inherited thrombophilia in women with unexplained fetal losses. Am J Obstet Gynecol 2002; 187: 1337-1342.
    • (2002) Am J Obstet Gynecol , vol.187 , pp. 1337-1342
    • Alonso, A.1    Soto, I.2    Urgelles, M.F.3
  • 18
    • 4444270353 scopus 로고    scopus 로고
    • High frequency of congenital thrombophilia in women with pathological pregnancies?
    • Rasmussen A, Ravn P. High frequency of congenital thrombophilia in women with pathological pregnancies? Acta Obstet Gynecol Scand 2004; 83: 808-817.
    • (2004) Acta Obstet Gynecol Scand , vol.83 , pp. 808-817
    • Rasmussen, A.1    Ravn, P.2
  • 19
    • 0033858679 scopus 로고    scopus 로고
    • Antiphospholipid and antiprotein syndromes in non-thrombotic, non-autoimmune women with unexplained recurrent primary early foetal loss. The Nimes Obstetricians and Haematologists Study - NOHA
    • Gris JC, Quere I, Sanmarco M et al. Antiphospholipid and antiprotein syndromes in non-thrombotic, non-autoimmune women with unexplained recurrent primary early foetal loss. The Nimes Obstetricians and Haematologists Study - NOHA. Thromb Haemost 2000; 84: 228-236.
    • (2000) Thromb Haemost , vol.84 , pp. 228-236
    • Gris, J.C.1    Quere, I.2    Sanmarco, M.3
  • 20
    • 0035017316 scopus 로고    scopus 로고
    • Factor V Leiden and acquired activated protein C resistance among 1000 women with recurrent miscarriage
    • Rai R, Shlebak A, Cohen H et al. Factor V Leiden and acquired activated protein C resistance among 1000 women with recurrent miscarriage. Hum Reprod 2001; 16: 961-965.
    • (2001) Hum Reprod , vol.16 , pp. 961-965
    • Rai, R.1    Shlebak, A.2    Cohen, H.3
  • 21
    • 0035989412 scopus 로고    scopus 로고
    • Prevalence of genetic markers for thrombophilia in recurrent pregnancy loss
    • Carp H, Salomon O, Seidman D et al. Prevalence of genetic markers for thrombophilia in recurrent pregnancy loss. Hum Reprod 2002; 17: 1633-1637.
    • (2002) Hum Reprod , vol.17 , pp. 1633-1637
    • Carp, H.1    Salomon, O.2    Seidman, D.3
  • 22
    • 1842637313 scopus 로고    scopus 로고
    • The association between adverse pregnancy outcomes and maternal factor V Leiden genotype: A meta-analysis
    • Dudding TE, Attia J. The association between adverse pregnancy outcomes and maternal factor V Leiden genotype: a meta-analysis. Thromb Haemost 2004; 91: 700-711.
    • (2004) Thromb Haemost , vol.91 , pp. 700-711
    • Dudding, T.E.1    Attia, J.2
  • 23
    • 1542287296 scopus 로고    scopus 로고
    • Evaluation of the association between hereditary thrombophilias and recurrent pregnancy loss: A meta-analysis
    • Kovalevsky G, Gracia CR, Berlin JA et al. Evaluation of the association between hereditary thrombophilias and recurrent pregnancy loss: a meta-analysis. Arch Intern Med 2004; 164: 558-563.
    • (2004) Arch Intern Med , vol.164 , pp. 558-563
    • Kovalevsky, G.1    Gracia, C.R.2    Berlin, J.A.3
  • 24
    • 0037443934 scopus 로고    scopus 로고
    • Thrombophilic disorders and fetal loss: A meta-analysis
    • Rey E, Kahn SR, David M et al. Thrombophilic disorders and fetal loss: a meta-analysis. Lancet 2003; 361: 901-908.
    • (2003) Lancet , vol.361 , pp. 901-908
    • Rey, E.1    Kahn, S.R.2    David, M.3
  • 25
    • 0032793325 scopus 로고    scopus 로고
    • The factor V Leiden mutation in Japanese couples with recurrent spontaneous abortion
    • Hashimoto K, Shizusawa Y, Shimoya K et al. The factor V Leiden mutation in Japanese couples with recurrent spontaneous abortion. Hum Reprod 1999; 14: 1872-1874.
    • (1999) Hum Reprod , vol.14 , pp. 1872-1874
    • Hashimoto, K.1    Shizusawa, Y.2    Shimoya, K.3
  • 26
    • 32544441595 scopus 로고    scopus 로고
    • The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) Study. Thrombophilia in pregnancy: a systematic review
    • Robertson L, Wu O, Langhorne P et al. The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) Study. Thrombophilia in pregnancy: a systematic review. Br J Haematol 2006; 132: 171-196.
    • (2006) Br J Haematol , vol.132 , pp. 171-196
    • Robertson, L.1    Wu, O.2    Langhorne, P.3
  • 27
    • 0032898194 scopus 로고    scopus 로고
    • Activated protein C resistance (FV:Q506) and pregnancy
    • Lindqvist PG, Svensson PJ, Marsaal K et al. Activated protein C resistance (FV:Q506) and pregnancy. Thromb Haemost 1999; 81: 532-537.
    • (1999) Thromb Haemost , vol.81 , pp. 532-537
    • Lindqvist, P.G.1    Svensson, P.J.2    Marsaal, K.3
  • 28
    • 0033964464 scopus 로고    scopus 로고
    • Prospective evaluation of the risk conferred by factor V Leiden and thermolabile methylenetetrahydrofolate reductase polymorphisms in pregnancy
    • Murphy RP, Donoghue C, Nallen RJ et al. Prospective evaluation of the risk conferred by factor V Leiden and thermolabile methylenetetrahydrofolate reductase polymorphisms in pregnancy. Arterioscler Thromb Vasc Biol 2000; 20: 266-270.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 266-270
    • Murphy, R.P.1    Donoghue, C.2    Nallen, R.J.3
  • 29
    • 0141503825 scopus 로고    scopus 로고
    • Thromboprophylaxis improves the live birth rate in women with consecutive recurrent miscarriages and hereditary thrombophilia
    • Carp H, Dolitzky M, Inbal A. Thromboprophylaxis improves the live birth rate in women with consecutive recurrent miscarriages and hereditary thrombophilia. J Thromb Haemost 2003; 1: 433-438.
    • (2003) J Thromb Haemost , vol.1 , pp. 433-438
    • Carp, H.1    Dolitzky, M.2    Inbal, A.3
  • 30
    • 0034912277 scopus 로고    scopus 로고
    • Low-molecular-weight heparin for the prevention of obstetric complications in women with thrombophilias
    • Kupfermine MJ, Fait G, Many A et al. Low-molecular-weight heparin for the prevention of obstetric complications in women with thrombophilias. Hypertens Pregnancy 2001; 20: 35-44.
    • (2001) Hypertens Pregnancy , vol.20 , pp. 35-44
    • Kupfermine, M.J.1    Fait, G.2    Many, A.3
  • 31
    • 0032932342 scopus 로고    scopus 로고
    • Safety of low-molecular-weight heparin in pregnancy: A systematic review
    • Sanson BJ, Lensing AW, Prins MH et al. Safety of low-molecular-weight heparin in pregnancy: a systematic review. Thromb Haemost 1999; 81: 668-672.
    • (1999) Thromb Haemost , vol.81 , pp. 668-672
    • Sanson, B.J.1    Lensing, A.W.2    Prins, M.H.3
  • 32
    • 0036987678 scopus 로고    scopus 로고
    • Thromboprophylaxis throughout pregnancy in women with previous history of recurrent miscarriages of unknown aetiology
    • Tzafettas J, Mamopoulos A, Anapliotis A et al. Thromboprophylaxis throughout pregnancy in women with previous history of recurrent miscarriages of unknown aetiology. Clin Exp Obstet Gynecol 2002; 29: 267-270.
    • (2002) Clin Exp Obstet Gynecol , vol.29 , pp. 267-270
    • Tzafettas, J.1    Mamopoulos, A.2    Anapliotis, A.3
  • 33
    • 2342633147 scopus 로고    scopus 로고
    • Low-molecular-weight heparin versus low-dose aspirin in women with one fetal loss and a constitutional thrombophilic disorder
    • Gris JC, Mercier E, Quere I et al. Low-molecular-weight heparin versus low-dose aspirin in women with one fetal loss and a constitutional thrombophilic disorder. Blood 2004; 103: 3695-3699.
    • (2004) Blood , vol.103 , pp. 3695-3699
    • Gris, J.C.1    Mercier, E.2    Quere, I.3
  • 34
    • 0025163726 scopus 로고
    • Epidemiology of preeclampsia and eclampsia in the United States, 1979-1986
    • Saftlas AF, Olson DR, Franks AL et al. Epidemiology of preeclampsia and eclampsia in the United States, 1979-1986. Am J Obstet Gynecol 1990; 163: 460-165.
    • (1990) Am J Obstet Gynecol , vol.163 , pp. 460-165
    • Saftlas, A.F.1    Olson, D.R.2    Franks, A.L.3
  • 35
    • 0029874642 scopus 로고    scopus 로고
    • HELLP syndrome associated with factor V R506Q mutation
    • Brenner B, Lanir N, Thaler I. HELLP syndrome associated with factor V R506Q mutation. Br J Haematol 1996; 92: 999-1001.
    • (1996) Br J Haematol , vol.92 , pp. 999-1001
    • Brenner, B.1    Lanir, N.2    Thaler, I.3
  • 36
    • 0029999583 scopus 로고    scopus 로고
    • The factor V Leiden mutation may predispose women to severe preeclampsia
    • Dizon-Townson DS, Nelson LM, Easton K et al. The factor V Leiden mutation may predispose women to severe preeclampsia. Am J Obstet Gynecol 1996; 175: 902-905.
    • (1996) Am J Obstet Gynecol , vol.175 , pp. 902-905
    • Dizon-Townson, D.S.1    Nelson, L.M.2    Easton, K.3
  • 37
    • 0033000764 scopus 로고    scopus 로고
    • High prevalence of hemostatic abnormalities in women with a history of severe preeclampsia
    • Van Pampus MG, Dekker GA, Wolf H et al. High prevalence of hemostatic abnormalities in women with a history of severe preeclampsia. Am J Obstet Gynecol 1999; 180: 1146-1150.
    • (1999) Am J Obstet Gynecol , vol.180 , pp. 1146-1150
    • Van Pampus, M.G.1    Dekker, G.A.2    Wolf, H.3
  • 38
    • 0041767403 scopus 로고    scopus 로고
    • Association of Leiden mutation in factor V gene with hypertension in pregnancy and pre-eclampsia: A meta-analysis
    • Kosmas IP, Tatsioni A, Ioannidis JP. Association of Leiden mutation in factor V gene with hypertension in pregnancy and pre-eclampsia: a meta-analysis. J Hypertens 2003; 21: 1221-1228.
    • (2003) J Hypertens , vol.21 , pp. 1221-1228
    • Kosmas, I.P.1    Tatsioni, A.2    Ioannidis, J.P.3
  • 39
    • 4344599724 scopus 로고    scopus 로고
    • Association of C677T polymorphism in the methylenetetrahydrofolate reductase gene with hypertension in pregnancy and pre-eclampsia: A meta-analysis
    • Kosmas IP, Tatsioni A, Ioannidis JP. Association of C677T polymorphism in the methylenetetrahydrofolate reductase gene with hypertension in pregnancy and pre-eclampsia: a meta-analysis. J Hypertens 2004; 22: 1655-1662.
    • (2004) J Hypertens , vol.22 , pp. 1655-1662
    • Kosmas, I.P.1    Tatsioni, A.2    Ioannidis, J.P.3
  • 40
    • 0036253127 scopus 로고    scopus 로고
    • Prothrombotic genotypes are not associated with pre-eclampsia and gestational hypertension: Results from a large population-based study and systematic review
    • Morrison ER, Miedzybrodzka ZH, Campbell DM et al. Prothrombotic genotypes are not associated with pre-eclampsia and gestational hypertension: results from a large population-based study and systematic review. Thromb Haemost 2002; 87: 779-785.
    • (2002) Thromb Haemost , vol.87 , pp. 779-785
    • Morrison, E.R.1    Miedzybrodzka, Z.H.2    Campbell, D.M.3
  • 41
    • 6844254526 scopus 로고    scopus 로고
    • Low-dose aspirin to prevent preeclampsia in women at high risk. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units
    • Caritis S, Sibai B, Hauth J et al. Low-dose aspirin to prevent preeclampsia in women at high risk. National Institute of Child Health and Human Development Network of Maternal-Fetal Medicine Units. N Engl J Med 1998; 338: 701-705.
    • (1998) N Engl J Med , vol.338 , pp. 701-705
    • Caritis, S.1    Sibai, B.2    Hauth, J.3
  • 42
    • 0036683413 scopus 로고    scopus 로고
    • Temporary increase in the risk for recurrence during pregnancy in women with a history of venous thromboembolism
    • Pabinger I, Grafenhofer H, Kyrle PA et al. Temporary increase in the risk for recurrence during pregnancy in women with a history of venous thromboembolism. Blood 2002; 100: 1060-1062.
    • (2002) Blood , vol.100 , pp. 1060-1062
    • Pabinger, I.1    Grafenhofer, H.2    Kyrle, P.A.3
  • 43
    • 0025216068 scopus 로고
    • Thrombosis and pregnancy in congenital deficiencies in AT III, protein C or protein S: Study of 78 women
    • Conard J, Horellou MH, van Dreden P et al. Thrombosis and pregnancy in congenital deficiencies in AT III, protein C or protein S: study of 78 women. Thromb Haemost 1990; 63: 319-320.
    • (1990) Thromb Haemost , vol.63 , pp. 319-320
    • Conard, J.1    Horellou, M.H.2    van Dreden, P.3
  • 44
    • 0029975366 scopus 로고    scopus 로고
    • Thrombotic risk in hereditary antithrombin III. protein C, or protein S deficiency. A cooperative, retrospective study. Gesellschaft fur Thrombose- und Hamostaseforschung Study Group on Natural Inhibitors
    • Pabinger I, Schneider B. Thrombotic risk in hereditary antithrombin III. protein C, or protein S deficiency. A cooperative, retrospective study. Gesellschaft fur Thrombose- und Hamostaseforschung Study Group on Natural Inhibitors. Arterioscler Thromb Vasc Biol 1996; 16: 742-748.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 742-748
    • Pabinger, I.1    Schneider, B.2
  • 45
    • 0024496352 scopus 로고
    • Recurrent thromboembolism in pregnancy and Puerperium. Is there a need for thromboprophylaxis?
    • Tengborn L, Bergqvist D, Matzsch T et al. Recurrent thromboembolism in pregnancy and Puerperium. Is there a need for thromboprophylaxis? Am J Obstet Gynecol 1989; 160: 90-94.
    • (1989) Am J Obstet Gynecol , vol.160 , pp. 90-94
    • Tengborn, L.1    Bergqvist, D.2    Matzsch, T.3
  • 46
    • 0034585516 scopus 로고    scopus 로고
    • Pregnancy-associated risk for venous thromboembolism and pregnancy outcome in women homozygous for factor V Leiden
    • Pabinger I, Nemes L, Rintelen C et al. Pregnancy-associated risk for venous thromboembolism and pregnancy outcome in women homozygous for factor V Leiden. Hematol J 2000; 1: 37-41.
    • (2000) Hematol J , vol.1 , pp. 37-41
    • Pabinger, I.1    Nemes, L.2    Rintelen, C.3
  • 47
    • 0034676551 scopus 로고    scopus 로고
    • Safety of withholding heparin in pregnant women with a history of venous thromboembolism. Recurrence of Clot in This Pregnancy Study Group
    • Brill-Edwards P, Ginsberg JS, Gent M et al. Safety of withholding heparin in pregnant women with a history of venous thromboembolism. Recurrence of Clot in This Pregnancy Study Group. N Engl J Med 2000; 343: 1439-1444.
    • (2000) N Engl J Med , vol.343 , pp. 1439-1444
    • Brill-Edwards, P.1    Ginsberg, J.S.2    Gent, M.3
  • 48
    • 23844450754 scopus 로고    scopus 로고
    • Risk of pregnancy-associated recurrent venous thromboembolism in women with a history of venous thrombosis
    • Pabinger I, Grafenhofer H, Kaider A et al. Risk of pregnancy-associated recurrent venous thromboembolism in women with a history of venous thrombosis. J Thromb Haemost 2005; 3: 949-954.
    • (2005) J Thromb Haemost , vol.3 , pp. 949-954
    • Pabinger, I.1    Grafenhofer, H.2    Kaider, A.3
  • 49
    • 0024357804 scopus 로고
    • Antiphospholipid antibodies and recurrent pregnancy loss
    • Triplett DA. Antiphospholipid antibodies and recurrent pregnancy loss. Am J Reprod Immunol 1989; 20: 52-67.
    • (1989) Am J Reprod Immunol , vol.20 , pp. 52-67
    • Triplett, D.A.1
  • 50
    • 0033522394 scopus 로고    scopus 로고
    • Increased risk for fetal loss in carriers of the factor V Leiden mutation
    • Meinardi JR, Middeldorp S, de Kam PJ et al. Increased risk for fetal loss in carriers of the factor V Leiden mutation. Ann Intern Med 1999; 130: 736-739.
    • (1999) Ann Intern Med , vol.130 , pp. 736-739
    • Meinardi, J.R.1    Middeldorp, S.2    de Kam, P.J.3
  • 51
    • 0032827489 scopus 로고    scopus 로고
    • The risk of fetal loss in family members of probands with factor V Leiden mutation
    • Tormene D, Simioni P, Prandoni P et al. The risk of fetal loss in family members of probands with factor V Leiden mutation. Thromb Haemost 1999; 82: 1237-1239.
    • (1999) Thromb Haemost , vol.82 , pp. 1237-1239
    • Tormene, D.1    Simioni, P.2    Prandoni, P.3
  • 52
    • 0035038413 scopus 로고    scopus 로고
    • Pre-eclampsia and fetal loss in women with a history of venous thromboembolism
    • Pabinger I, Grafenhofer H, Kaider A et al. Pre-eclampsia and fetal loss in women with a history of venous thromboembolism. Arterioscler Thromb Vasc Biol 2001; 21: 874-879.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 874-879
    • Pabinger, I.1    Grafenhofer, H.2    Kaider, A.3
  • 53
    • 5144222292 scopus 로고    scopus 로고
    • Hereditary thrombophilia and fetal loss: A prospective follow-up study
    • Vossen CY, Preston FE, Conard J et al. Hereditary thrombophilia and fetal loss: a prospective follow-up study. J Thromb Haemost 2004; 2: 592-596.
    • (2004) J Thromb Haemost , vol.2 , pp. 592-596
    • Vossen, C.Y.1    Preston, F.E.2    Conard, J.3
  • 54
    • 0031022366 scopus 로고    scopus 로고
    • Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies)
    • Rai R, Cohen H, Dave M et al. Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies). Br Med J 1997; 314: 253-257.
    • (1997) Br Med J , vol.314 , pp. 253-257
    • Rai, R.1    Cohen, H.2    Dave, M.3
  • 55
    • 0029934389 scopus 로고    scopus 로고
    • Antiphospholipid antibody-associated recurrent pregnancy loss: Treatment with heparin and low-dose aspirin is superior to low-dose aspirin alone
    • Kutteh WH. Antiphospholipid antibody-associated recurrent pregnancy loss: treatment with heparin and low-dose aspirin is superior to low-dose aspirin alone. Am J Obstet Gynecol 1996; 174: 1584-1589.
    • (1996) Am J Obstet Gynecol , vol.174 , pp. 1584-1589
    • Kutteh, W.H.1
  • 56
    • 0036711316 scopus 로고    scopus 로고
    • Antiphospholipid syndrome in pregnancy: A randomized, controlled trial of treatment
    • Farquharson RG, Quenby S, GreavesM. Antiphospholipid syndrome in pregnancy: a randomized, controlled trial of treatment. Obstet Gynecol 2002; 100: 408-113.
    • (2002) Obstet Gynecol , vol.100 , pp. 408-113
    • Farquharson, R.G.1    Quenby, S.2    GreavesM3
  • 57
    • 36949015392 scopus 로고    scopus 로고
    • EThIG Investigators. Risk stratification and heparin prophylaxis to prevent venous thromboembolism in pregnant women
    • Bauersachs RM, Dudenhausen J, Faridi A et al. EThIG Investigators. Risk stratification and heparin prophylaxis to prevent venous thromboembolism in pregnant women. Thromb Haemost 2007; 98: 1237-1245.
    • (2007) Thromb Haemost , vol.98 , pp. 1237-1245
    • Bauersachs, R.M.1    Dudenhausen, J.2    Faridi, A.3
  • 58
    • 22144466236 scopus 로고    scopus 로고
    • Low-molecular-weight heparins for thromboprophylaxis and treatment of venous thromboembolism in pregnancy: A systematic review of safety and efficacy
    • Greer IA, Nelson-Piercy C. Low-molecular-weight heparins for thromboprophylaxis and treatment of venous thromboembolism in pregnancy: a systematic review of safety and efficacy. Blood 2005; 106: 401-407.
    • (2005) Blood , vol.106 , pp. 401-407
    • Greer, I.A.1    Nelson-Piercy, C.2


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