Low-dose aspirin to prevent preeclampsia in women at high risk

New England Journal of Medicine

Volumn 338, Issue 11, 1998, Pages 701-705

  Caritis, Steve ^a,m   Sibai, Baha ^b   Hauth, John ^c   Lindheimer, Marshall D ^d   Klebanoff, Mark ^k   Thom, Elizabeth ^l   Vandorsten, Peter ^e   Landon, Mark ^f   Paul, Richard ^g   Miodovnik, Menachem ^h   Meis, Paul ⁱ   Thurnau, Gary ^j   Bottoms, Sidney ⁿ   McNellis, Donald ^o   Roberts, James M ^p  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

^e MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^f OHIO STATE UNIVERSITY   (United States)

^g UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^h UNIVERSITY OF CINCINNATI   (United States)

ⁱ WAKE FOREST SCHOOL OF MEDICINE   (United States)

^j UNIVERSITY OF OKLAHOMA   (United States)

^k EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^l GEORGE WASHINGTON UNIVERSITY   (United States)

^m UNIVERSITY OF PITTSBURGH   (United States)

ⁿ WAYNE STATE UNIVERSITY   (United States)

^o National Institute of Child Health

^p UNIVERSITY OF PITTSBURGH   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTIHYPERTENSIVE AGENT; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; INSULIN; LACTATE DEHYDROGENASE; PROTEIN;

ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DIABETES MELLITUS; DOUBLE BLIND PROCEDURE; FEMALE; HIGH RISK POPULATION; HUMAN; HYPERTENSION; INCIDENCE; MAJOR CLINICAL STUDY; MULTICENTER STUDY; PREECLAMPSIA; PRIORITY JOURNAL; PROPHYLAXIS; PROTEINURIA; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ADULT; ASPIRIN; CHRONIC DISEASE; DIABETES MELLITUS, TYPE 1; DOUBLE-BLIND METHOD; FEMALE; HUMANS; HYPERTENSION; INCIDENCE; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY COMPLICATIONS, CARDIOVASCULAR; PREGNANCY IN DIABETICS; PREGNANCY OUTCOME; PREGNANCY TRIMESTER, SECOND; PREGNANCY, MULTIPLE; RISK FACTORS;

EID: 6844254526     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM199803123381101     Document Type: Article

References (18)

1. Beaufils M, Uzan S, Donsimoni R, Colau JC. Prevention of pre-eclampsia by early antiplatelet therapy. Lancet 1985;1:840-2.
2. Wallenburg HCS, Dekker GA, Makovitz JW, Rotmans E Low-dose aspirin prevents pregnancy-induced hypertension and pre-eclampsia in angiotensin-sensitive primigravidae. Lancet 1986;1:1-3.
3. 2 to prostacyclin in relatively high risk pregnancies. N Engl J Med 1989;321:351-6.
4. Uzan S, Beaufils M, Breart G, Bazin B, Capitant C, Paris J. Prevention of fetal growth retardation with low-dose aspirin: findings of the EPREDA trial. Lancet 1991;337:1427-31.
5. Hauth JC, Goldenberg RL, Parker CR Jr, et al. Low-dose aspirin therapy to prevent preeclampsia. Am J Obstet Gynecol 1993;168:1083-91.
6. Italian Study of Aspirin in Pregnancy. Low-dose aspirin in prevention and treatment of intrauterine growth retardation and pregnancy-induced hypertension. Lancet 1993;341:396-400.
7. Sibai BM, Caritis SN, Thorn E, et al. Prevention of preeclampsia with low-dose aspirin in healthy, nulliparous pregnant women. N Engl J Med 1993;329:1213-8.
8. CLASP (Collaborative Low-dose Aspirin Study in Pregnancy) Collaborative Group. CLASP: a randomised trial of low-dose aspirin for the prevention and treatment of pre-eclampsia among 9364 pregnant women. Lancet 1994;343:619-29.
9. ECPPA (Estudo Colaborativo para Prevenção da Pré-eclampsia com Aspirina) Collaborative Group. ECPPA: randomised trial of low dose aspirin for the prevention of maternal and fetal complications in high risk pregnant women. Br J Obstet Gynecol 1996;103:39-47.
10. Rotchell YE, Cruickshank JK, Phillips-Gay M, et al. Barbados Low-dose Aspirin Study in Pregnancy (BLASP): a randomised trial for the prevention of pre-eclampsia and its complications. Br J Obstet Gynaecol (in press).
11. Golding J. A randomised trial of low dose aspirin for primiparae in pregnancy. Br J Obstet Gynaecol (in press).
12. Grant J. Multicentre trials in obstetrics and gynaecology: smaller explanatory trials are required. Br J Obstet Gynaecol 1996;103:599-602.
13. Brenner WE, Edelman DA, Hendricks CH. A standard of fetal growth for the United States of America. Am J Obstet Gynecol 1976;126:555-64.
14. Naeye RL, Benirschke K, Hagstrom JW, Marcus CC. Intrauterine growth of twins as estimated from liveborn birth-weight data. Pediatrics 1966;37:409-16.
15. Intracranial hemorrhage: germinal matrix - intraventricular hemorrhage of the premature infant. In: Volpe JJ. Neurology of the newborn. 3rd ed. Philadelphia: W.B. Saunders, 1995:403-63.
16. Viinikka L, Harrikamen-Sorri AL, Lumme R, Hiilesmaa V, Ylikorkala O. Low dose aspirin in hypertensive pregnant women: effect on pregnancy outcome and prostacyclin-thromboxane balance in mother and newborn. Br J Obstet Gynaecol 1993;100:809-15.
17. Collins R. Antiplatelet agents for IUGR and preeclampsia. Revised May 4, 1994. In: Keirse MJNC, Renfrew MJ, Neilson JP, Crowther C, eds. Pregnancy and childbirth module. In: The Cochrane pregnancy and childbirth database: the Cochrane Collaboration, issue 2. Oxford, England: Update Software, 1995 (software).
18. Pipkin B, Crowther C, de Swiet M, et al. Where next for prophylaxis against pre-eclampsia? Br J Obstet Gynaecol 1996;103:603-7.