메뉴 건너뛰기




Volumn 197, Issue 2, 2008, Pages 89-98

Autologous and allogeneic hematopoietic stem cell transplantation for Multiple Sclerosis: Perspective on mechanisms of action

Author keywords

Allogeneic; Autologous; Bone marrow transplantation; Hematopoietic stem cell transplantation; Multiple Sclerosis; Treatment

Indexed keywords

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; CLINICAL STUDY; DISEASE FREE SURVIVAL; FOLLOW UP; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; THERAPY EFFECT; TREATMENT OUTCOME;

EID: 46649107295     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2008.04.030     Document Type: Review
Times cited : (19)

References (89)
  • 1
    • 43949160858 scopus 로고
    • A differential-avidity model for T-cell selection
    • Ashton-Rickardt P.G., and Tonegawa S. A differential-avidity model for T-cell selection. Immunol. Today. 15 (1994) 362-366
    • (1994) Immunol. Today. , vol.15 , pp. 362-366
    • Ashton-Rickardt, P.G.1    Tonegawa, S.2
  • 2
    • 33748319513 scopus 로고    scopus 로고
    • Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice
    • Bettelli E., Baeten D., Jager A., Sobel R.A., and Kuchroo V.K. Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice. J. Clin. Invest. 116 (2006) 2393-2402
    • (2006) J. Clin. Invest. , vol.116 , pp. 2393-2402
    • Bettelli, E.1    Baeten, D.2    Jager, A.3    Sobel, R.A.4    Kuchroo, V.K.5
  • 3
    • 0027389929 scopus 로고
    • Relative susceptibility of SJL/J and B10.S mice to experimental allergic encephalomyelitis (EAE) is determined by the ability of prethymic cells in bone marrow to develop into EAE effector T cells
    • Binder T.A., Greiner D.L., Grunnet M., and Goldschneider I. Relative susceptibility of SJL/J and B10.S mice to experimental allergic encephalomyelitis (EAE) is determined by the ability of prethymic cells in bone marrow to develop into EAE effector T cells. J. Neuroimmunol. 42 (1993) 23-32
    • (1993) J. Neuroimmunol. , vol.42 , pp. 23-32
    • Binder, T.A.1    Greiner, D.L.2    Grunnet, M.3    Goldschneider, I.4
  • 4
    • 18044398996 scopus 로고    scopus 로고
    • Evolution of brain-derived neurotrophic factor levels after autologous hematopoietic stem cell transplantation in multiple sclerosis
    • Blanco Y., Saiz A., Costa M., et al. Evolution of brain-derived neurotrophic factor levels after autologous hematopoietic stem cell transplantation in multiple sclerosis. Neurosci. Lett. 380 (2005) 122-126
    • (2005) Neurosci. Lett. , vol.380 , pp. 122-126
    • Blanco, Y.1    Saiz, A.2    Costa, M.3
  • 5
    • 0029048591 scopus 로고
    • Syngeneic bone marrow transplantation eliminates V beta 8.2 T lymphocytes from the spinal cord of Lewis rats with experimental allergic encephalomyelitis
    • Burt R.K., Burns W., Ruvolo P., et al. Syngeneic bone marrow transplantation eliminates V beta 8.2 T lymphocytes from the spinal cord of Lewis rats with experimental allergic encephalomyelitis. J. Neurosci. Res. 41 (1995) 526-531
    • (1995) J. Neurosci. Res. , vol.41 , pp. 526-531
    • Burt, R.K.1    Burns, W.2    Ruvolo, P.3
  • 6
    • 0141593519 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation for progressive multiple sclerosis: failure of a total body irradiation-based conditioning regimen to prevent disease progression in patients with high disability scores
    • Burt R.K., Cohen B.A., Russell E., et al. Hematopoietic stem cell transplantation for progressive multiple sclerosis: failure of a total body irradiation-based conditioning regimen to prevent disease progression in patients with high disability scores. Blood 102 (2003) 2373-2378
    • (2003) Blood , vol.102 , pp. 2373-2378
    • Burt, R.K.1    Cohen, B.A.2    Russell, E.3
  • 7
    • 4043099123 scopus 로고    scopus 로고
    • Induction of remission of severe and refractory rheumatoid arthritis by allogeneic mixed chimerism
    • Burt R.K., Oyama Y., Verda L., et al. Induction of remission of severe and refractory rheumatoid arthritis by allogeneic mixed chimerism. Arthritis. Rheum. 50 (2004) 2466-2470
    • (2004) Arthritis. Rheum. , vol.50 , pp. 2466-2470
    • Burt, R.K.1    Oyama, Y.2    Verda, L.3
  • 8
    • 0032055153 scopus 로고    scopus 로고
    • Effect of disease stage on clinical outcome after syngeneic bone marrow transplantation for relapsing experimental autoimmune encephalomyelitis
    • Burt R.K., Padilla J., Begolka W.S., Canto M.C., and Miller S.D. Effect of disease stage on clinical outcome after syngeneic bone marrow transplantation for relapsing experimental autoimmune encephalomyelitis. Blood 91 (1998) 2609-2616
    • (1998) Blood , vol.91 , pp. 2609-2616
    • Burt, R.K.1    Padilla, J.2    Begolka, W.S.3    Canto, M.C.4    Miller, S.D.5
  • 9
    • 0031907910 scopus 로고    scopus 로고
    • T cell-depleted autologous hematopoietic stem cell transplantation for multiple sclerosis: report on the first three patients
    • Burt R.K., Traynor A.E., Cohen B., et al. T cell-depleted autologous hematopoietic stem cell transplantation for multiple sclerosis: report on the first three patients. Bone. Marrow. Transplant. 21 (1998) 537-541
    • (1998) Bone. Marrow. Transplant. , vol.21 , pp. 537-541
    • Burt, R.K.1    Traynor, A.E.2    Cohen, B.3
  • 10
    • 0032533235 scopus 로고    scopus 로고
    • Treatment of autoimmune disease by intense immunosuppressive conditioning and autologous hematopoietic stem cell transplantation
    • Burt R.K., Traynor A.E., Pope R., et al. Treatment of autoimmune disease by intense immunosuppressive conditioning and autologous hematopoietic stem cell transplantation. Blood 92 (1998) 3505-3514
    • (1998) Blood , vol.92 , pp. 3505-3514
    • Burt, R.K.1    Traynor, A.E.2    Pope, R.3
  • 11
    • 0347264750 scopus 로고    scopus 로고
    • CD34+ selected autologous peripheral blood stem cell transplantation for multiple sclerosis: report of toxicity and treatment results at one year of follow-up in 15 patients
    • Carreras E., Saiz A., Marin P., et al. CD34+ selected autologous peripheral blood stem cell transplantation for multiple sclerosis: report of toxicity and treatment results at one year of follow-up in 15 patients. Haematologica 88 (2003) 306-314
    • (2003) Haematologica , vol.88 , pp. 306-314
    • Carreras, E.1    Saiz, A.2    Marin, P.3
  • 12
    • 34447331302 scopus 로고    scopus 로고
    • Disease progression after bone marrow transplantation in a model of multiple sclerosis is associated with chronic microglial and glial progenitor response
    • Cassiani-Ingoni R., Muraro P.A., Magnus T., et al. Disease progression after bone marrow transplantation in a model of multiple sclerosis is associated with chronic microglial and glial progenitor response. J. Neuropathol. Exp. Neurol. 66 (2007) 637-649
    • (2007) J. Neuropathol. Exp. Neurol. , vol.66 , pp. 637-649
    • Cassiani-Ingoni, R.1    Muraro, P.A.2    Magnus, T.3
  • 13
    • 5344272503 scopus 로고    scopus 로고
    • Multiple sclerosis is not an autoimmune disease
    • Chaudhuri A., and Behan P.O. Multiple sclerosis is not an autoimmune disease. Arch. Neurol. 61 (2004) 1610-1612
    • (2004) Arch. Neurol. , vol.61 , pp. 1610-1612
    • Chaudhuri, A.1    Behan, P.O.2
  • 14
    • 33745875004 scopus 로고    scopus 로고
    • Brain atrophy after immunoablation and stem cell transplantation in multiple sclerosis
    • Chen J.T., Collins D.L., Atkins H.L., Freedman M.S., Galal A., and Arnold D.L. Brain atrophy after immunoablation and stem cell transplantation in multiple sclerosis. Neurology 66 (2006) 1935-1937
    • (2006) Neurology , vol.66 , pp. 1935-1937
    • Chen, J.T.1    Collins, D.L.2    Atkins, H.L.3    Freedman, M.S.4    Galal, A.5    Arnold, D.L.6
  • 15
    • 33244469927 scopus 로고    scopus 로고
    • Age at disability milestones in multiple sclerosis
    • Confavreux C., and Vukusic S. Age at disability milestones in multiple sclerosis. Brain 129 (2006) 595-605
    • (2006) Brain , vol.129 , pp. 595-605
    • Confavreux, C.1    Vukusic, S.2
  • 16
    • 33244466021 scopus 로고    scopus 로고
    • Natural history of multiple sclerosis: a unifying concept
    • Confavreux C., and Vukusic S. Natural history of multiple sclerosis: a unifying concept. Brain 129 (2006) 606-616
    • (2006) Brain , vol.129 , pp. 606-616
    • Confavreux, C.1    Vukusic, S.2
  • 17
    • 0034720664 scopus 로고    scopus 로고
    • Assessment of thymic output in adults after haematopoietic stem-cell transplantation and prediction of T-cell reconstitution
    • Douek D.C., Vescio R.A., Betts M.R., et al. Assessment of thymic output in adults after haematopoietic stem-cell transplantation and prediction of T-cell reconstitution. Lancet 355 (2000) 1875-1881
    • (2000) Lancet , vol.355 , pp. 1875-1881
    • Douek, D.C.1    Vescio, R.A.2    Betts, M.R.3
  • 18
    • 18044399829 scopus 로고    scopus 로고
    • Genetic susceptibility to MS: a second stage analysis in Canadian MS families
    • Dyment D.A., Willer C.J., Scott B., et al. Genetic susceptibility to MS: a second stage analysis in Canadian MS families. Neurogenetics 3 (2001) 145-151
    • (2001) Neurogenetics , vol.3 , pp. 145-151
    • Dyment, D.A.1    Willer, C.J.2    Scott, B.3
  • 19
    • 0022868088 scopus 로고
    • A population-based study of multiple sclerosis in twins
    • Ebers G.C., Bulman D.E., Sadovnick A.D., et al. A population-based study of multiple sclerosis in twins. N. Engl. J. Med. 315 (1986) 1638-1642
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1638-1642
    • Ebers, G.C.1    Bulman, D.E.2    Sadovnick, A.D.3
  • 20
    • 0032494792 scopus 로고    scopus 로고
    • Placebo-controlled multicentre randomised trial of interferon beta-1b in treatment of secondary progressive multiple sclerosis. European Study Group on interferon beta-1b in secondary progressive MS
    • European Study Group. Placebo-controlled multicentre randomised trial of interferon beta-1b in treatment of secondary progressive multiple sclerosis. European Study Group on interferon beta-1b in secondary progressive MS. Lancet 352 (1998) 1491-1497
    • (1998) Lancet , vol.352 , pp. 1491-1497
    • European Study Group1
  • 21
    • 0034093120 scopus 로고    scopus 로고
    • Autologous stem cell transplantation in progressive multiple sclerosis- an interim analysis of efficacy
    • Fassas A., Anagnostopoulos A., Kazis A., et al. Autologous stem cell transplantation in progressive multiple sclerosis- an interim analysis of efficacy. J. Clin. Immunol. 20 (2000) 24-30
    • (2000) J. Clin. Immunol. , vol.20 , pp. 24-30
    • Fassas, A.1    Anagnostopoulos, A.2    Kazis, A.3
  • 22
    • 0030714110 scopus 로고    scopus 로고
    • Peripheral blood stem cell transplantation in the treatment of progressive multiple sclerosis: first results of a pilot study
    • Fassas A., Anagnostopoulos A., Kazis A., et al. Peripheral blood stem cell transplantation in the treatment of progressive multiple sclerosis: first results of a pilot study. Bone. Marrow. Transplant. 20 (1997) 631-638
    • (1997) Bone. Marrow. Transplant. , vol.20 , pp. 631-638
    • Fassas, A.1    Anagnostopoulos, A.2    Kazis, A.3
  • 23
    • 18544374335 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation for multiple sclerosis. A retrospective multicenter study
    • Fassas A., Passweg J.R., Anagnostopoulos A., et al. Hematopoietic stem cell transplantation for multiple sclerosis. A retrospective multicenter study. J. Neurol. 249 (2002) 1088-1097
    • (2002) J. Neurol. , vol.249 , pp. 1088-1097
    • Fassas, A.1    Passweg, J.R.2    Anagnostopoulos, A.3
  • 24
    • 0032170052 scopus 로고    scopus 로고
    • Immune reconstitution and immunotherapy after autologous hematopoietic stem cell transplantation
    • Guillaume T., Rubinstein D.B., and Symann M. Immune reconstitution and immunotherapy after autologous hematopoietic stem cell transplantation. Blood 92 (1998) 1471-1490
    • (1998) Blood , vol.92 , pp. 1471-1490
    • Guillaume, T.1    Rubinstein, D.B.2    Symann, M.3
  • 25
    • 0037153729 scopus 로고    scopus 로고
    • Mitoxantrone in progressive multiple sclerosis: a placebo-controlled, double-blind, randomised, multicentre trial
    • Hartung H.P., Gonsette R., Konig N., et al. Mitoxantrone in progressive multiple sclerosis: a placebo-controlled, double-blind, randomised, multicentre trial. Lancet 360 (2002) 2018-2025
    • (2002) Lancet , vol.360 , pp. 2018-2025
    • Hartung, H.P.1    Gonsette, R.2    Konig, N.3
  • 26
    • 3042551054 scopus 로고    scopus 로고
    • Discordant functional and inflammatory parameters in multiple sclerosis patients after autologous haematopoietic stem cell transplantation
    • Healey K.M., Pavletic S.Z., Al Omaishi J., et al. Discordant functional and inflammatory parameters in multiple sclerosis patients after autologous haematopoietic stem cell transplantation. Mult. Scler. 10 (2004) 284-289
    • (2004) Mult. Scler. , vol.10 , pp. 284-289
    • Healey, K.M.1    Pavletic, S.Z.2    Al Omaishi, J.3
  • 27
    • 23944511180 scopus 로고    scopus 로고
    • Tolerance induction by bone marrow transplantation in a multiple sclerosis model
    • Herrmann M.M., Gaertner S., Stadelmann C., et al. Tolerance induction by bone marrow transplantation in a multiple sclerosis model. Blood 106 (2005) 1875-1883
    • (2005) Blood , vol.106 , pp. 1875-1883
    • Herrmann, M.M.1    Gaertner, S.2    Stadelmann, C.3
  • 28
    • 0037530472 scopus 로고    scopus 로고
    • Thymic export function and T cell homeostasis in patients with relapsing remitting multiple sclerosis
    • Hug A., Korporal M., Schroder I., et al. Thymic export function and T cell homeostasis in patients with relapsing remitting multiple sclerosis. J. Immunol. 171 (2003) 432-437
    • (2003) J. Immunol. , vol.171 , pp. 432-437
    • Hug, A.1    Korporal, M.2    Schroder, I.3
  • 29
    • 1642482932 scopus 로고    scopus 로고
    • Brain tissue loss occurs after suppression of enhancement in patients with multiple sclerosis treated with autologous haematopoietic stem cell transplantation
    • Inglese M., Mancardi G.L., Pagani E., et al. Brain tissue loss occurs after suppression of enhancement in patients with multiple sclerosis treated with autologous haematopoietic stem cell transplantation. J. Neurol. Neurosurg. Psychiatry. 75 (2004) 643-644
    • (2004) J. Neurol. Neurosurg. Psychiatry. , vol.75 , pp. 643-644
    • Inglese, M.1    Mancardi, G.L.2    Pagani, E.3
  • 30
    • 32444447027 scopus 로고    scopus 로고
    • Prevention of spontaneous arthritis by inhibiting homeostatic expansion of autoreactive CD4+ T cells in the K/BxN mouse model
    • Jang E., Kim H.R., Cho S.H., et al. Prevention of spontaneous arthritis by inhibiting homeostatic expansion of autoreactive CD4+ T cells in the K/BxN mouse model. Arthritis. Rheum. 54 (2006) 492-498
    • (2006) Arthritis. Rheum. , vol.54 , pp. 492-498
    • Jang, E.1    Kim, H.R.2    Cho, S.H.3
  • 31
    • 38449091801 scopus 로고    scopus 로고
    • Failure of allogeneic bone marrow transplantation to arrest disease activity in multiple sclerosis
    • Jeffery D.R. Failure of allogeneic bone marrow transplantation to arrest disease activity in multiple sclerosis. Mult. Scler. (2007)
    • (2007) Mult. Scler.
    • Jeffery, D.R.1
  • 32
    • 0027210448 scopus 로고
    • Induction of experimental autoimmune encephalomyelitis in severe combined immunodeficient mice reconstituted with allogeneic or xenogeneic hematopoietic cells
    • Jones R.E., Bourdette D.N., Whitham R.H., Offner H., and Vandenbark A.A. Induction of experimental autoimmune encephalomyelitis in severe combined immunodeficient mice reconstituted with allogeneic or xenogeneic hematopoietic cells. J. Immunol. 150 (1993) 4620-4629
    • (1993) J. Immunol. , vol.150 , pp. 4620-4629
    • Jones, R.E.1    Bourdette, D.N.2    Whitham, R.H.3    Offner, H.4    Vandenbark, A.A.5
  • 33
    • 0033042841 scopus 로고    scopus 로고
    • Acute/relapsing experimental autoimmune encephalomyelitis: induction of long lasting, antigen-specific tolerance by syngeneic bone marrow transplantation
    • Karussis D., Vourka-Karussis U., Mizrachi-Koll R., and Abramsky O. Acute/relapsing experimental autoimmune encephalomyelitis: induction of long lasting, antigen-specific tolerance by syngeneic bone marrow transplantation. Mult. Scler. 5 (1999) 17-21
    • (1999) Mult. Scler. , vol.5 , pp. 17-21
    • Karussis, D.1    Vourka-Karussis, U.2    Mizrachi-Koll, R.3    Abramsky, O.4
  • 34
    • 0026704053 scopus 로고
    • Chronic-relapsing experimental autoimmune encephalomyelitis (CR-EAE): treatment and induction of tolerance, with high dose cyclophosphamide followed by syngeneic bone marrow transplantation
    • Karussis D.M., Slavin S., Ben Nun A., et al. Chronic-relapsing experimental autoimmune encephalomyelitis (CR-EAE): treatment and induction of tolerance, with high dose cyclophosphamide followed by syngeneic bone marrow transplantation. J. Neuroimmunol. 39 (1992) 201-210
    • (1992) J. Neuroimmunol. , vol.39 , pp. 201-210
    • Karussis, D.M.1    Slavin, S.2    Ben Nun, A.3
  • 35
    • 0026604243 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis and induction of tolerance with acute immunosuppression followed by syngeneic bone marrow transplantation
    • Karussis D.M., Slavin S., Lehmann D., Mizrachi-Koll R., Abramsky O., and Ben Nun A. Prevention of experimental autoimmune encephalomyelitis and induction of tolerance with acute immunosuppression followed by syngeneic bone marrow transplantation. J. Immunol. 148 (1992) 1693-1698
    • (1992) J. Immunol. , vol.148 , pp. 1693-1698
    • Karussis, D.M.1    Slavin, S.2    Lehmann, D.3    Mizrachi-Koll, R.4    Abramsky, O.5    Ben Nun, A.6
  • 36
    • 0027329005 scopus 로고
    • Prevention and reversal of adoptively transferred, chronic relapsing experimental autoimmune encephalomyelitis with a single high dose cytoreductive treatment followed by syngeneic bone marrow transplantation
    • Karussis D.M., Vourka-Karussis U., Lehmann D., et al. Prevention and reversal of adoptively transferred, chronic relapsing experimental autoimmune encephalomyelitis with a single high dose cytoreductive treatment followed by syngeneic bone marrow transplantation. J. Clin. Invest. 92 (1993) 765-772
    • (1993) J. Clin. Invest. , vol.92 , pp. 765-772
    • Karussis, D.M.1    Vourka-Karussis, U.2    Lehmann, D.3
  • 37
    • 10044287310 scopus 로고    scopus 로고
    • Nonmyeloablative stem cell transplant in a patient with advanced systemic sclerosis and systemic lupus erythematosus
    • Khorshid O., Hosing C., Bibawi S., et al. Nonmyeloablative stem cell transplant in a patient with advanced systemic sclerosis and systemic lupus erythematosus. J. Rheumatol. 31 (2004) 2513-2516
    • (2004) J. Rheumatol. , vol.31 , pp. 2513-2516
    • Khorshid, O.1    Hosing, C.2    Bibawi, S.3
  • 38
    • 20144363585 scopus 로고    scopus 로고
    • Recent immune status determines the source of antigens that drive homeostatic T cell expansion
    • Kieper W.C., Troy A., Burghardt J.T., et al. Recent immune status determines the source of antigens that drive homeostatic T cell expansion. J. Immunol. 174 (2005) 3158-3163
    • (2005) J. Immunol. , vol.174 , pp. 3158-3163
    • Kieper, W.C.1    Troy, A.2    Burghardt, J.T.3
  • 39
    • 0036838536 scopus 로고    scopus 로고
    • Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis
    • Kohm A.P., Carpentier P.A., Anger H.A., and Miller S.D. Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis. J. Immunol. 169 (2002) 4712-4716
    • (2002) J. Immunol. , vol.169 , pp. 4712-4716
    • Kohm, A.P.1    Carpentier, P.A.2    Anger, H.A.3    Miller, S.D.4
  • 40
    • 0035350915 scopus 로고    scopus 로고
    • Immunoablative therapy with autologous stem cell transplantation in the treatment of poor risk multiple sclerosis
    • Kozak T., Havrdova E., Pit'ha J., et al. Immunoablative therapy with autologous stem cell transplantation in the treatment of poor risk multiple sclerosis. Transplant. Proc. 33 (2001) 2179-2181
    • (2001) Transplant. Proc. , vol.33 , pp. 2179-2181
    • Kozak, T.1    Havrdova, E.2    Pit'ha, J.3
  • 41
    • 0034060611 scopus 로고    scopus 로고
    • High-dose immunosuppressive therapy with PBPC support in the treatment of poor risk multiple sclerosis
    • Kozak T., Havrdova E., Pit'ha J., et al. High-dose immunosuppressive therapy with PBPC support in the treatment of poor risk multiple sclerosis. Bone. Marrow. Transplant. 25 (2000) 525-531
    • (2000) Bone. Marrow. Transplant. , vol.25 , pp. 525-531
    • Kozak, T.1    Havrdova, E.2    Pit'ha, J.3
  • 42
    • 33748302945 scopus 로고    scopus 로고
    • Spontaneous opticospinal encephalomyelitis in a double-transgenic mouse model of autoimmune T cell/B cell cooperation
    • Krishnamoorthy G., Lassmann H., Wekerle H., and Holz A. Spontaneous opticospinal encephalomyelitis in a double-transgenic mouse model of autoimmune T cell/B cell cooperation. J. Clin. Invest. 116 (2006) 2385-2392
    • (2006) J. Clin. Invest. , vol.116 , pp. 2385-2392
    • Krishnamoorthy, G.1    Lassmann, H.2    Wekerle, H.3    Holz, A.4
  • 43
    • 2542447203 scopus 로고    scopus 로고
    • Allogeneic hematopoietic stem cell transplantation in a patient affected by large granular lymphocyte leukemia and multiple sclerosis
    • La Nasa G., Littera R., Cocco E., Battistini L., Marrosu M.G., and Contu L. Allogeneic hematopoietic stem cell transplantation in a patient affected by large granular lymphocyte leukemia and multiple sclerosis. Ann. Hematol. 83 (2004) 403-405
    • (2004) Ann. Hematol. , vol.83 , pp. 403-405
    • La Nasa, G.1    Littera, R.2    Cocco, E.3    Battistini, L.4    Marrosu, M.G.5    Contu, L.6
  • 44
    • 23844506444 scopus 로고    scopus 로고
    • Multiple sclerosis pathology: evolution of pathogenetic concepts
    • Lassmann H. Multiple sclerosis pathology: evolution of pathogenetic concepts. Brain. Pathol. 15 (2005) 217-222
    • (2005) Brain. Pathol. , vol.15 , pp. 217-222
    • Lassmann, H.1
  • 45
    • 33646948505 scopus 로고    scopus 로고
    • Non-myeloablative allogeneic stem cell transplant in a patient with refractory systemic lupus erythematosus
    • Lu Q., Lu L., Niu X., Guo Y., Parino G.R., and Liu D. Non-myeloablative allogeneic stem cell transplant in a patient with refractory systemic lupus erythematosus. Bone. Marrow. Transplant. 37 (2006) 979-981
    • (2006) Bone. Marrow. Transplant. , vol.37 , pp. 979-981
    • Lu, Q.1    Lu, L.2    Niu, X.3    Guo, Y.4    Parino, G.R.5    Liu, D.6
  • 46
    • 0035838312 scopus 로고    scopus 로고
    • Autologous hematopoietic stem cell transplantation suppresses Gd-enhanced MRI activity in MS
    • Mancardi G.L., Saccardi R., Filippi M., et al. Autologous hematopoietic stem cell transplantation suppresses Gd-enhanced MRI activity in MS. Neurology 57 (2001) 62-68
    • (2001) Neurology , vol.57 , pp. 62-68
    • Mancardi, G.L.1    Saccardi, R.2    Filippi, M.3
  • 48
    • 0031053084 scopus 로고    scopus 로고
    • Allogeneic bone marrow transplant for chronic myelogenous leukemia in a patient with multiple sclerosis
    • McAllister L.D., Beatty P.G., and Rose J. Allogeneic bone marrow transplant for chronic myelogenous leukemia in a patient with multiple sclerosis. Bone. Marrow. Transplant. 19 (1997) 395-397
    • (1997) Bone. Marrow. Transplant. , vol.19 , pp. 395-397
    • McAllister, L.D.1    Beatty, P.G.2    Rose, J.3
  • 49
    • 34249749383 scopus 로고    scopus 로고
    • Autologous haematopoietic stem cell transplantation fails to stop demyelination and neurodegeneration in multiple sclerosis
    • Metz I., Lucchinetti C.F., Openshaw H., et al. Autologous haematopoietic stem cell transplantation fails to stop demyelination and neurodegeneration in multiple sclerosis. Brain 130 Pt 5 (2007) 1254-1262
    • (2007) Brain , vol.130 , Issue.PART 5 , pp. 1254-1262
    • Metz, I.1    Lucchinetti, C.F.2    Openshaw, H.3
  • 50
    • 0033472729 scopus 로고    scopus 로고
    • Effect of interferon-beta1b on magnetic resonance imaging outcomes in secondary progressive multiple sclerosis: results of a European multicenter, randomized, double-blind, placebo-controlled trial. European Study Group on Interferon-beta1b in secondary progressive multiple sclerosis
    • Miller D.H., Molyneux P.D., Barker G.J., MacManus D.G., Moseley I.F., and Wagner K. Effect of interferon-beta1b on magnetic resonance imaging outcomes in secondary progressive multiple sclerosis: results of a European multicenter, randomized, double-blind, placebo-controlled trial. European Study Group on Interferon-beta1b in secondary progressive multiple sclerosis. Ann. Neurol. 46 (1999) 850-859
    • (1999) Ann. Neurol. , vol.46 , pp. 850-859
    • Miller, D.H.1    Molyneux, P.D.2    Barker, G.J.3    MacManus, D.G.4    Moseley, I.F.5    Wagner, K.6
  • 51
    • 0016153945 scopus 로고
    • Transplantation of autoimmune potential. I. Development of antinuclear antibodies in H-2 histocompatible recipients of bone marrow from New Zealand Black mice
    • Morton J.I., and Siegel B.V. Transplantation of autoimmune potential. I. Development of antinuclear antibodies in H-2 histocompatible recipients of bone marrow from New Zealand Black mice. Proc. Natl. Acad. Sci. U. S. A. 71 (1974) 2162-2165
    • (1974) Proc. Natl. Acad. Sci. U. S. A. , vol.71 , pp. 2162-2165
    • Morton, J.I.1    Siegel, B.V.2
  • 52
    • 32344452280 scopus 로고    scopus 로고
    • Renewing the T cell repertoire to arrest autoimmune aggression
    • Muraro P.A., and Douek D.C. Renewing the T cell repertoire to arrest autoimmune aggression. Trends. Immunol. 27 (2006) 61-67
    • (2006) Trends. Immunol. , vol.27 , pp. 61-67
    • Muraro, P.A.1    Douek, D.C.2
  • 53
    • 20144386375 scopus 로고    scopus 로고
    • Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients
    • Muraro P.A., Douek D.C., Packer A., et al. Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients. J. Exp. Med. 201 (2005) 805-816
    • (2005) J. Exp. Med. , vol.201 , pp. 805-816
    • Muraro, P.A.1    Douek, D.C.2    Packer, A.3
  • 54
    • 0141816715 scopus 로고    scopus 로고
    • High-dose immunosuppressive therapy and autologous peripheral blood stem cell transplantation for severe multiple sclerosis
    • Nash R.A., Bowen J.D., McSweeney P.A., et al. High-dose immunosuppressive therapy and autologous peripheral blood stem cell transplantation for severe multiple sclerosis. Blood 102 (2003) 2364-2372
    • (2003) Blood , vol.102 , pp. 2364-2372
    • Nash, R.A.1    Bowen, J.D.2    McSweeney, P.A.3
  • 55
    • 12144289198 scopus 로고    scopus 로고
    • Epstein-Barr virus-associated posttransplantation lymphoproliferative disorder after high-dose immunosuppressive therapy and autologous CD34-selected hematopoietic stem cell transplantation for severe autoimmune diseases
    • Nash R.A., Dansey R., Storek J., et al. Epstein-Barr virus-associated posttransplantation lymphoproliferative disorder after high-dose immunosuppressive therapy and autologous CD34-selected hematopoietic stem cell transplantation for severe autoimmune diseases. Biol. Blood. Marrow. Transplant. 9 (2003) 583-591
    • (2003) Biol. Blood. Marrow. Transplant. , vol.9 , pp. 583-591
    • Nash, R.A.1    Dansey, R.2    Storek, J.3
  • 56
    • 0029762023 scopus 로고    scopus 로고
    • Review: cytokines and the pathogenesis of multiple sclerosis
    • Navikas V., and Link H. Review: cytokines and the pathogenesis of multiple sclerosis. J. Neurosci. Res. 45 (1996) 322-333
    • (1996) J. Neurosci. Res. , vol.45 , pp. 322-333
    • Navikas, V.1    Link, H.2
  • 57
    • 33745627452 scopus 로고    scopus 로고
    • Autologous hematopoietic stem cell transplantation for progressive multiple sclerosis: report of efficacy and safety at three yr of follow up in 21 patients
    • Ni X.S., Ouyang J., Zhu W.H., Wang C., and Chen B. Autologous hematopoietic stem cell transplantation for progressive multiple sclerosis: report of efficacy and safety at three yr of follow up in 21 patients. Clin. Transplant. 20 (2006) 485-489
    • (2006) Clin. Transplant. , vol.20 , pp. 485-489
    • Ni, X.S.1    Ouyang, J.2    Zhu, W.H.3    Wang, C.4    Chen, B.5
  • 58
    • 0037782265 scopus 로고    scopus 로고
    • Management of multiple sclerosis: current trials and future options
    • Noseworthy J.H. Management of multiple sclerosis: current trials and future options. Curr. Opin. Neurol. 16 (2003) 289-297
    • (2003) Curr. Opin. Neurol. , vol.16 , pp. 289-297
    • Noseworthy, J.H.1
  • 59
    • 0034576841 scopus 로고    scopus 로고
    • Peripheral blood stem cell transplantation in multiple sclerosis with busulfan and cyclophosphamide conditioning: report of toxicity and immunological monitoring
    • Openshaw H., Lund B.T., Kashyap A., et al. Peripheral blood stem cell transplantation in multiple sclerosis with busulfan and cyclophosphamide conditioning: report of toxicity and immunological monitoring. Biol. Blood. Marrow. Transplant. 6 (2000) 563-575
    • (2000) Biol. Blood. Marrow. Transplant. , vol.6 , pp. 563-575
    • Openshaw, H.1    Lund, B.T.2    Kashyap, A.3
  • 60
    • 0036159001 scopus 로고    scopus 로고
    • Engraftment syndrome: a common cause for rash and fever following autologous hematopoietic stem cell transplantation for multiple sclerosis
    • Oyama Y., Cohen B., Traynor A., Brush M., Rodriguez J., and Burt R.K. Engraftment syndrome: a common cause for rash and fever following autologous hematopoietic stem cell transplantation for multiple sclerosis. Bone. Marrow. Transplant. 29 (2002) 81-85
    • (2002) Bone. Marrow. Transplant. , vol.29 , pp. 81-85
    • Oyama, Y.1    Cohen, B.2    Traynor, A.3    Brush, M.4    Rodriguez, J.5    Burt, R.K.6
  • 61
    • 0024458480 scopus 로고
    • Genetic resistance in experimental autoimmune encephalomyelitis. I. Analysis of the mechanism of LeR resistance using radiation chimeras
    • Pelfrey C.M., Waxman F.J., and Whitacre C.C. Genetic resistance in experimental autoimmune encephalomyelitis. I. Analysis of the mechanism of LeR resistance using radiation chimeras. Cell. Immunol. 122 (1989) 504-516
    • (1989) Cell. Immunol. , vol.122 , pp. 504-516
    • Pelfrey, C.M.1    Waxman, F.J.2    Whitacre, C.C.3
  • 62
    • 33644584352 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis
    • Polman C.H., O'Connor P.W., Havrdova E., et al. A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis. N. Engl. J. Med. 354 (2006) 899-910
    • (2006) N. Engl. J. Med. , vol.354 , pp. 899-910
    • Polman, C.H.1    O'Connor, P.W.2    Havrdova, E.3
  • 63
    • 0035084166 scopus 로고    scopus 로고
    • Immune reconstitution after autologous hematopoietic stem cell transplantation
    • Porrata L.F., Litzow M.R., and Markovic S.N. Immune reconstitution after autologous hematopoietic stem cell transplantation. Mayo. Clin. Proc. 76 (2001) 407-412
    • (2001) Mayo. Clin. Proc. , vol.76 , pp. 407-412
    • Porrata, L.F.1    Litzow, M.R.2    Markovic, S.N.3
  • 64
    • 0038176068 scopus 로고    scopus 로고
    • Cellular and humoral immune reconstitution after autologous peripheral blood stem cell transplantation (PBSCT)
    • Reimer P., Kunzmann V., Wilhelm M., et al. Cellular and humoral immune reconstitution after autologous peripheral blood stem cell transplantation (PBSCT). Ann. Hematol. 82 (2003) 263-270
    • (2003) Ann. Hematol. , vol.82 , pp. 263-270
    • Reimer, P.1    Kunzmann, V.2    Wilhelm, M.3
  • 65
    • 0033617472 scopus 로고    scopus 로고
    • A new look at MHC and autoimmune disease
    • Ridgway W.M., Fasso M., and Fathman C.G. A new look at MHC and autoimmune disease. Science 284 (1999) 749-751
    • (1999) Science , vol.284 , pp. 749-751
    • Ridgway, W.M.1    Fasso, M.2    Fathman, C.G.3
  • 66
    • 35349012123 scopus 로고    scopus 로고
    • A three-year study of brain atrophy after autologous hematopoietic stem cell transplantation in rapidly evolving secondary progressive multiple sclerosis
    • Rocca M.A., Mondria T., Valsasina P., et al. A three-year study of brain atrophy after autologous hematopoietic stem cell transplantation in rapidly evolving secondary progressive multiple sclerosis. AJNR. Am. J. Neuroradiol. 28 (2007) 1659-1661
    • (2007) AJNR. Am. J. Neuroradiol. , vol.28 , pp. 1659-1661
    • Rocca, M.A.1    Mondria, T.2    Valsasina, P.3
  • 67
    • 34848868292 scopus 로고    scopus 로고
    • The long-term effect of AHSCT on MRI measures of MS evolution: a five-year follow-up study
    • Roccatagliata L., Rocca M.A., Valsasina P., et al. The long-term effect of AHSCT on MRI measures of MS evolution: a five-year follow-up study. Multiple. Sclerosis. 13 (2007) 1068-1070
    • (2007) Multiple. Sclerosis. , vol.13 , pp. 1068-1070
    • Roccatagliata, L.1    Rocca, M.A.2    Valsasina, P.3
  • 68
    • 33846297365 scopus 로고    scopus 로고
    • Autologous stem cell transplantation for progressive multiple sclerosis: update of the European group for Blood and Marrow Transplantation autoimmune diseases working party database
    • Saccardi R., Kozak T., Bocelli-Tyndall C., et al. Autologous stem cell transplantation for progressive multiple sclerosis: update of the European group for Blood and Marrow Transplantation autoimmune diseases working party database. Mult. Scler. 12 (2006) 814-823
    • (2006) Mult. Scler. , vol.12 , pp. 814-823
    • Saccardi, R.1    Kozak, T.2    Bocelli-Tyndall, C.3
  • 69
    • 20144368500 scopus 로고    scopus 로고
    • Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: impact on disease activity and quality of life
    • Saccardi R., Mancardi G.L., Solari A., et al. Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: impact on disease activity and quality of life. Blood 105 (2005) 2601-2607
    • (2005) Blood , vol.105 , pp. 2601-2607
    • Saccardi, R.1    Mancardi, G.L.2    Solari, A.3
  • 70
    • 0027537583 scopus 로고
    • A population-based study of multiple sclerosis in twins: update
    • Sadovnick A.D., Armstrong H., Rice G.P., et al. A population-based study of multiple sclerosis in twins: update. Ann. Neurol. 33 (1993) 281-285
    • (1993) Ann. Neurol. , vol.33 , pp. 281-285
    • Sadovnick, A.D.1    Armstrong, H.2    Rice, G.P.3
  • 71
    • 0842347341 scopus 로고    scopus 로고
    • Clinical and MRI outcome after autologous hematopoietic stem cell transplantation in MS
    • Saiz A., Blanco Y., Carreras E., et al. Clinical and MRI outcome after autologous hematopoietic stem cell transplantation in MS. Neurology 62 (2004) 282-284
    • (2004) Neurology , vol.62 , pp. 282-284
    • Saiz, A.1    Blanco, Y.2    Carreras, E.3
  • 72
    • 0035942351 scopus 로고    scopus 로고
    • MRI and CSF oligoclonal bands after autologous hematopoietic stem cell transplantation in MS
    • Saiz A., Carreras E., Berenguer J., et al. MRI and CSF oligoclonal bands after autologous hematopoietic stem cell transplantation in MS. Neurology 56 (2001) 1084-1089
    • (2001) Neurology , vol.56 , pp. 1084-1089
    • Saiz, A.1    Carreras, E.2    Berenguer, J.3
  • 73
    • 29644432533 scopus 로고    scopus 로고
    • Intense T cell depletion followed by autologous bone marrow transplantation for severe multiple sclerosis
    • Samijn J.P., Te Boekhorst P.A., Mondria T., et al. Intense T cell depletion followed by autologous bone marrow transplantation for severe multiple sclerosis. J. Neurol. Neurosurg. Psychiatry. 77 (2006) 46-50
    • (2006) J. Neurol. Neurosurg. Psychiatry. , vol.77 , pp. 46-50
    • Samijn, J.P.1    Te Boekhorst, P.A.2    Mondria, T.3
  • 74
    • 0030779118 scopus 로고    scopus 로고
    • A mechanism for the major histocompatibility complex-linked resistance to autoimmunity
    • Schmidt D., Verdaguer J., Averill N., and Santamaria P. A mechanism for the major histocompatibility complex-linked resistance to autoimmunity. J. Exp. Med. 186 (1997) 1059-1075
    • (1997) J. Exp. Med. , vol.186 , pp. 1059-1075
    • Schmidt, D.1    Verdaguer, J.2    Averill, N.3    Santamaria, P.4
  • 75
    • 0034718378 scopus 로고    scopus 로고
    • Long-term effect of bone-marrow transplantation for childhood-onset cerebral X-linked adrenoleukodystrophy
    • Shapiro E., Krivit W., Lockman L., et al. Long-term effect of bone-marrow transplantation for childhood-onset cerebral X-linked adrenoleukodystrophy. Lancet 356 (2000) 713-718
    • (2000) Lancet , vol.356 , pp. 713-718
    • Shapiro, E.1    Krivit, W.2    Lockman, L.3
  • 76
    • 0033168523 scopus 로고    scopus 로고
    • Fas-FasL-mediated CD4+ T-cell apoptosis following stem cell transplantation
    • Singh R.K., Varney M.L., Buyukberber S., et al. Fas-FasL-mediated CD4+ T-cell apoptosis following stem cell transplantation. Cancer. Res. 59 (1999) 3107-3111
    • (1999) Cancer. Res. , vol.59 , pp. 3107-3111
    • Singh, R.K.1    Varney, M.L.2    Buyukberber, S.3
  • 78
    • 33750345757 scopus 로고    scopus 로고
    • Autologous peripheral blood stem cell transplantation for severe multiple sclerosis
    • Su L., Xu J., Ji B.X., et al. Autologous peripheral blood stem cell transplantation for severe multiple sclerosis. Int. J. Hematol. 84 (2006) 276-281
    • (2006) Int. J. Hematol. , vol.84 , pp. 276-281
    • Su, L.1    Xu, J.2    Ji, B.X.3
  • 79
    • 2442504914 scopus 로고    scopus 로고
    • Characteristics of T-cell receptor repertoire and myelin-reactive T cells reconstituted from autologous haematopoietic stem-cell grafts in multiple sclerosis
    • Sun W., Popat U., Hutton G., et al. Characteristics of T-cell receptor repertoire and myelin-reactive T cells reconstituted from autologous haematopoietic stem-cell grafts in multiple sclerosis. Brain 127 (2004) 996-1008
    • (2004) Brain , vol.127 , pp. 996-1008
    • Sun, W.1    Popat, U.2    Hutton, G.3
  • 80
    • 0035025762 scopus 로고    scopus 로고
    • Mixed chimerism and transplant tolerance
    • Sykes M. Mixed chimerism and transplant tolerance. Immunity 14 (2001) 417-424
    • (2001) Immunity , vol.14 , pp. 417-424
    • Sykes, M.1
  • 81
    • 0035037147 scopus 로고    scopus 로고
    • Resolution of sarcoidosis after allogeneic bone marrow transplantation with donor lymphocyte infusions
    • Tauro S., and Mahendra P. Resolution of sarcoidosis after allogeneic bone marrow transplantation with donor lymphocyte infusions. Bone. Marrow. Transplant. 27 (2001) 757-759
    • (2001) Bone. Marrow. Transplant. , vol.27 , pp. 757-759
    • Tauro, S.1    Mahendra, P.2
  • 82
    • 0027499661 scopus 로고
    • Treatment of experimental allergic encephalomyelitis in rats with total body irradiation and syngeneic BMT
    • van Gelder M., Kinwel-Bohre E.P., and van Bekkum D.W. Treatment of experimental allergic encephalomyelitis in rats with total body irradiation and syngeneic BMT. Bone. Marrow. Transplant. 11 (1993) 233-241
    • (1993) Bone. Marrow. Transplant. , vol.11 , pp. 233-241
    • van Gelder, M.1    Kinwel-Bohre, E.P.2    van Bekkum, D.W.3
  • 83
    • 0029743390 scopus 로고    scopus 로고
    • Treatment of relapsing experimental autoimmune encephalomyelitis with largely MHC-matched allogeneic bone marrow transplantation
    • van Gelder M., Mulder A.H., and van Bekkum D.W. Treatment of relapsing experimental autoimmune encephalomyelitis with largely MHC-matched allogeneic bone marrow transplantation. Transplantation 62 (1996) 810-818
    • (1996) Transplantation , vol.62 , pp. 810-818
    • van Gelder, M.1    Mulder, A.H.2    van Bekkum, D.W.3
  • 84
    • 0029163335 scopus 로고
    • Treatment of relapsing experimental autoimmune encephalomyelitis in rats with allogeneic bone marrow transplantation from a resistant strain
    • van Gelder M., and van Bekkum D.W. Treatment of relapsing experimental autoimmune encephalomyelitis in rats with allogeneic bone marrow transplantation from a resistant strain. Bone. Marrow. Transplant. 16 (1995) 343-351
    • (1995) Bone. Marrow. Transplant. , vol.16 , pp. 343-351
    • van Gelder, M.1    van Bekkum, D.W.2
  • 85
    • 0030462050 scopus 로고    scopus 로고
    • Effective treatment of relapsing experimental autoimmune encephalomyelitis with pseudoautologous bone marrow transplantation
    • van Gelder M., and van Bekkum D.W. Effective treatment of relapsing experimental autoimmune encephalomyelitis with pseudoautologous bone marrow transplantation. Bone. Marrow. Transplant. 18 (1996) 1029-1034
    • (1996) Bone. Marrow. Transplant. , vol.18 , pp. 1029-1034
    • van Gelder, M.1    van Bekkum, D.W.2
  • 86
    • 34248665856 scopus 로고    scopus 로고
    • Allogeneic bone marrow transplantation in models of experimental autoimmune encephalomyelitis: evidence for a graft-versus-autoimmunity effect
    • Van Wijmeersch B., Sprangers B., Rutgeerts O., et al. Allogeneic bone marrow transplantation in models of experimental autoimmune encephalomyelitis: evidence for a graft-versus-autoimmunity effect. Biol. Blood. Marrow. Transplant. 13 (2007) 627-637
    • (2007) Biol. Blood. Marrow. Transplant. , vol.13 , pp. 627-637
    • Van Wijmeersch, B.1    Sprangers, B.2    Rutgeerts, O.3
  • 87
    • 33744904725 scopus 로고    scopus 로고
    • Secondary progressive in contrast to relapsing-remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T-cell function and FOXP3 expression
    • Venken K., Hellings N., Hensen K., et al. Secondary progressive in contrast to relapsing-remitting multiple sclerosis patients show a normal CD4+CD25+ regulatory T-cell function and FOXP3 expression. J. Neurosci. Res. 83 (2006) 1432-1446
    • (2006) J. Neurosci. Res. , vol.83 , pp. 1432-1446
    • Venken, K.1    Hellings, N.2    Hensen, K.3
  • 88
    • 1842732224 scopus 로고    scopus 로고
    • Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
    • Viglietta V., Baecher-Allan C., Weiner H.L., and Hafler D.A. Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J. Exp. Med. 199 (2004) 971-979
    • (2004) J. Exp. Med. , vol.199 , pp. 971-979
    • Viglietta, V.1    Baecher-Allan, C.2    Weiner, H.L.3    Hafler, D.A.4
  • 89
    • 33751431058 scopus 로고    scopus 로고
    • Clinical outcomes after autologous haematopoietic stem cell transplantation in patients with progressive multiple sclerosis
    • Xu J., Ji B.X., Su L., Dong H.Q., Sun X.J., and Liu C.Y. Clinical outcomes after autologous haematopoietic stem cell transplantation in patients with progressive multiple sclerosis. Chin. Med. J. (Engl.). 119 (2006) 1851-1855
    • (2006) Chin. Med. J. (Engl.). , vol.119 , pp. 1851-1855
    • Xu, J.1    Ji, B.X.2    Su, L.3    Dong, H.Q.4    Sun, X.J.5    Liu, C.Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.