Effect of disease stage on clinical outcome after syngeneic bone marrow transplantation for relapsing experimental autoimmune encephalomyelitis

Blood

Volumn 91, Issue 7, 1998, Pages 2609-2616

  Burt, Richard K ^a   Padilla, Josette ^b   Begolka, Wendy Smith ^b   Dal Canto, Mauro C ^b   Miller, Stephen D ^b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW TRANSPLANTATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; INTERFERON PRODUCTION; ISOTRANSPLANTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0032055153     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.7.2609.2609_2609_2616     Document Type: Article

References (32)

1. Marmont AM, van Bekkum DW: Stem cell transplantation for severe autoimmune diseases: New proposals but still unanswered questions. Bone Marrow Transplant 16:497, 1995
2. Burt RK, Burns W, Hess A: Bone marrow transplantation for multiple sclerosis. Bone Marrow Transplant 16:1, 1995
3. Marmont AM, Tyndall A, Gratwohl A, Vischer T: Hematopoietic precursor stem cell transplantation for autoimmune diseases. Lancet 345:978, 1995
4. Brocke S, Gijbels K, Steinman L: Experimental autoimmune encephalomyelitis in the mouse, in Cohen IR, Miller A (eds): Autoimmune Disease Models: A Guidebook. San Diego, CA, Academic Press, 1994, p 1
5. Steinman L, Schwartz G, Waldor M, et al: in EAE: A Good Model for MS. 1984, p 393
6. Arnon R: Experimental allergic encephalomyelitis-Susceptibility and suppression. Immunol Rev 55:5, 1981
7. Zamvil SS, et al: T cell epitope of the autoantigen myelin basic protein that induces encephalomyelitis. Nature 324:258, 1986
8. Ando DG, Clayton J, Kono D, et al: Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype. Cell Immunol 124:132, 1989
9. Brown AM, McFarlin DE: Relapsing experimental allergic encephalomyelitis in the SJL/J mouse. Lab Invest 45:278, 1981
10. Driscoll BF, Kies MW, Alvord EC: The nature of the defect in experimental allergic encephalomyelitis (EAE)-resistant Lewis (Le-R) rats. J Immunol 134:1567, 1985
11. Baker D, O'Neill JK, Turk JL: Cytokines in the central nervous system of mice during chronic relapsing experimental allergic encephalomyelitis. Cell Immunol 134:505, 1991
12. McRae BL, Kennedy MK, Tan LJ, Dal Canto MC, Picha KS, Miller SD: Induction of active and adoptive relapsing experimental autoimmune encephalomyelitis (EAE) using an encephalitogenic epitope of proteolipid protein. J Neuroimmunol 38:229, 1992
13. Mor F, Cohen IR: Shifts in epitopes of myelin basic protein recognized by Lewis rat T cells before, during, and after the induction of experimental autoimmune encephalomyelitis. J Clin Invest 92:2199, 1993
14. Lehmann PV, Forsthuber T, Miller A, Sercarz EE: Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen. Nature 358:155, 1992
15. Miller SD, Tan LJ, Pope L, McRae BL, Karpus WJ: Antigen specific tolerance as a therapy for experimental autoimmune encephalomyelitis. Int Rev Immunol 9:203, 1992
16. McRae BL, Vanderlugt CL, Dal Canto MC, Miller SD: Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis. J Exp Med 182:75, 1995
17. Yu M, Johnson JM, Tuohy VK: A predictable sequential determinant spreading cascade invariably accompanies progression of experimental autoimmune encephalomyelitis: A basis for peptide specific therapy after onset of disease. J Exp Med 183:1777, 1996
18. Reiner SL, Zheng S, Corry DB, Locksley RM: Constructing polycompetitor cDNAs for quantitative PCR. J Immunol Methods 165:37, 1993
19. Passas A, Annagnostopoulos, Kazis A, Kapinas K, Sakellari I, Kimiskidis V, Tsompanakou A: Peripheral blood stem cell transplantation in the treatment of progressive multiple sclerosis: First results of a pilot study. Bone Marrow Transplant 20:631, 1997
20. Bun RK, Traynor AE, Cohen B, et al: T cell depleted autologous hematopoietic stem cell transplantation for multiple sclerosis: Report on the first three patients. Bone Marrow Transplant, 1998 (in press)
21. β8.2T lymphocytes from the spinal cord of Lewis rats with experimental allergic encephalomyelitis. J Neurosci Res 41:526, 1995
22. van Gelder M, van Bekkum DW: Treatment of relapsing experimental autoimmune encephalomyelitis in rats with allogeneic bone marrow transplantation from a resistant strain. Bone Marrow Transplant 16:343, 1995
23. van Gelder M, Mulder AH, van Bekkum DW: Treatment of relapsing experimental autoimmune encephalomyelitis with largely MHC-matched allogeneic bone marrow transplantation. Transplantation 62:810, 1996
24. van Gelder M, van Bekkum DW: Effective treatment of relapsing experimental autoimmune encephalomyelitis with pseudoautologous bone marrow transplantation. Bone Marrow Transplant 18:1029, 1996
25. Karussis DM, Vourka-Karussis U, Lehmann D, et al: Prevention and reversal of adoptively transferred, chronic relapsing experimental autoimmune encephalomyelitis with a single high dose cytoreductive treatment followed by syngeneic bone marrow transplantation. J Clin Invest 92:765, 1993
26. Dijkstra CD, De Groot CJA, Huitinga I: The role of macrophages in demyelination. J Neuroimmunol 40:183, 1992
27. Thorton SC, Walsh BJ, Bennett S, Robbins JM, Foulcher E, Morgan GW, Penny R, Breit SN: Both in vitro and in vivo irradiation are associated with induction of macrophage-derived fibroblast growth factors. Clin Exp Immunol 103:67, 1996
28. Olsen GA, Gockerman JP, Bast RC, et al: Altered immunologic reconstitution after standard dose chemotherapy or high dose chemotherapy with autologous bone marrow support. Transplantation 46:57, 1988
29. Barbarese E, Scares H, Yang S, Clark RB: Comparison of CNS homing pattern among murine TH cell lines responsvie to myelin basic protein. J Neuroimmunol 39:151, 1992
30. 14C-labeled cells during acute, chronic, and relapsing experimental allergic encephalomyelitis. Lab Invest 63:162, 1990
31. Karin N, Szafer F, Mitchell D, Gold DP, Steinman L: Selective and nonselective stages of homing of T lymphocytes to the central nervous system during experimental allergic encephalomyelitis. J Immunol 150:4116, 1993
32. Yu M, Nishiyama A, Trapp BD, Tuohy VK: Interferon-beta inhibits progression of relapsing remitting experimental autoimmune encephalomyelitis. J Neuroimmunol 64:91, 1996