Effects of new ubiquinone-imidazo[2,1-b]thiazoles on mitochondrial complex I (NADH-ubiquinone reductase) and on mitochondrial permeability transition pore

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 21, 2004, Pages 5525-5532

  Andreani, Aldo ^a   Granaiola, Massimiliano ^a   Leoni, Alberto ^a   Locatelli, Alessandra ^a   Morigi, Rita ^a   Rambaldi, Mirella ^a   Recanatini, Maurizio ^a   Lenaz, Giorgio ^a   Fato, Romana ^a   Bergamini, Christian ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 CHLORO 6 METHYLIMIDAZO[2,1 B]THIAZOLE; 2 CHLORO 6 METHYLIMIDAZO[2,1 B]THIAZOLE 5 CARBOXALDEHYDE; BENZOQUINONE DERIVATIVE; CARBENE; IMIDAZOLE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; THIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; DRUG SYNTHESIS; ELECTRON; IC 50; MALE; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NONHUMAN; PERMEABILITY; RAT; VELOCITY;

ANIMALS; CATTLE; ELECTRON TRANSPORT COMPLEX I; ENZYME ACTIVATION; IMIDAZOLES; MALE; MITOCHONDRIA, HEART; MITOCHONDRIA, LIVER; PERMEABILITY; RATS; RATS, WISTAR; THIAZOLES; UBIQUINONE;

EID: 4644316145     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.08.012     Document Type: Article

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