Variability in cytokine production and cell proliferation by mitogen-activated ovine peripheral blood mononuclear cells: Modulation by interleukin (IL)-10 and IL-12

Veterinary Immunology and Immunopathology

Volumn 102, Issue 1-2, 2004, Pages 67-76

  Wattegedera, S ^a   Sills, K ^a   Howard, C J ^b   Hope, J C ^b   McInnes, C J ^a   Entrican, G ^a  

^a MOREDUN RESEARCH INSTITUTE   (United Kingdom)

^b INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

Author keywords

Cytokine modulation; IFN ; IL 10; IL 12; Ovine

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; MITOGENIC AGENT; RECOMBINANT INTERLEUKIN 10; RECOMBINANT INTERLEUKIN 12;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CYTOKINE PRODUCTION; FEMALE; IMMUNOASSAY; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; SHEEP;

ANIMALS; CONCANAVALIN A; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-12; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; RECOMBINANT PROTEINS; SHEEP;

ANIMALIA; OVIS; OVIS ARIES; RODENTIA;

EID: 4644297361     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetimm.2004.06.006     Document Type: Article

References (28)

1. C.R. Bebbington Use of vectors based on gene amplification for the expression of cloned genes in mammalian cells In: DNA Cloning 4, Mammalian Systems. second ed. 1995 Oxford University Press Chapter 3
2. S.S. Chan, I. McConnell, and B.A. Blacklaws Generation and characterization of ovine dendritic cells derived from peripheral blood monocytes Immunology 107 2002 366 372
3. D.W. Coltman, K. Wilson, J.G. Pilkington, M.J. Stear, and J.M. Pemberton A microsatellite polymorphism in the gamma interferon gene is associated with resistance to gastrointestinal nematodes in a naturally-parasitized population of Soay sheep Parasitology 122 2001 571 582
4. R. De Rose, J.P. Scheerlinck, G. Casey, P.R. Wood, J.M. Tennent, and P.J. Chaplin Ovine interleukin-12: analysis of biologic function and species comparison J. Interferon Cytokine Res. 20 2000 557 564
5. G. Entrican New technologies for studying immune regulation in ruminants Vet. Immunol. Immunopathol. 87 2002 485 490
6. G. Entrican, D. Deane, M. MacLean, L. Inglis, J. Thomson, C. McInnes, and D.M. Haig Development of a sandwich ELISA for ovine granulocyte/macrophage colony-stimulating factor Vet. Immunol. Immunopathol. 50 1996 105 115
7. S.P. Graham, G.E. Jones, M. MacLean, M. Livingstone, and G. Entrican Recombinant ovine interferon gamma inhibits the multiplication of Chlamydia psittaci in ovine cells J. Comp. Pathol. 112 1995 185 195
8. + T-cell activation, protection from apoptosis, and enhanced cytokine production Cell Immunol. 222 2003 45 57
9. D.M. Haig, J. Thomson, C.J. McInnes, D.L. Deane, I.E. Anderson, C.A. McCaughan, W. Imlach, A.A. Mercer, C.J. Howard, and S.B. Fleming A comparison of the anti-inflammatory and immuno-stimulatory activities of orf virus and ovine interleukin-10 Virus Res. 90 2002 303 316
10. J.C. Hope, L.S. Kwong, G. Entrican, S. Wattegedera, H.M. Vordermeier, P. Sopp, and C.J. Howard Development of detection methods for ruminant interleukin (IL)-12 J. Immunol. Methods 266 2002 117 126
11. N.H. Hunt, and G.E. Grau Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria Trends Immunol. 24 2003 491 499
12. E.A. Innes, W.R. Panton, K.M. Thomson, S. Maley, and D. Buxton Kinetics of interferon gamma production in vivo during infection with the S48 vaccine strain of Toxoplasma gondii J. Comp. Pathol. 113 1995 89 94
13. P. Kalinski, C.M. Hilkens, E.A. Wierenga, and M.L. Kapsenberg T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal Immunol. Today 20 1999 561 567
14. + cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype Nature 421 2003 388 392
15. J.R. Kirman, and R.A. Seder DNA vaccination: the answer to stable, protective T-cell memory? Curr. Opin. Immunol. 15 2003 471 476
16. L.S. Kwong, J.C. Hope, M.L. Thom, P. Sopp, S. Duggan, G.P. Bembridge, and C.J. Howard Development of an ELISA for bovine IL-10 Vet. Immunol. Immunopathol. 85 2002 213 223
17. K.W. Moore, M.R. de Waal, R.L. Coffman, and A. O'Garra Interleukin-10 and the interleukin-10 receptor Annu. Rev. Immunol. 19 2001 683 765
18. T.R. Mosmann, and R.L. Coffman TH-1 and TH-2 cells: different patterns of lymphokine secretion lead to different functional properties Annu. Rev. Immunol. 7 1989 145 173
19. V. Pravica, C. Perrey, A. Stevens, J.H. Lee, and I.V. Hutchinson A single nucleotide polymorphism in the first intron of the human IFN-gamma gene: absolute correlation with a polymorphic CA microsatellite marker of high IFN-gamma production Hum. Immunol. 61 2000 863 866
20. S.L. Reiner Helper T-cell differentiation, inside and out Curr. Opin. Immunol. 13 2001 351 355
21. J. Rengarajan, S.J. Szabo, and L.H. Glimcher Transcriptional regulation of Th1/Th2 polarization Immunol. Today 21 2000 479 483
22. M. Rossouw, H.J. Nel, G.S. Cooke, P.D. van Helden, and E.G. Hoal Association between tuberculosis and a polymorphic NFkappaB binding site in the interferon gamma gene Lancet 361 2003 1871 1872
23. J.F. Schlaak, E. Schmitt, C. Huls, K.H. Meyer zum Buschenfelde, and B. Fleischer A sensitive and specific bioassay for the detection of human interleukin-10 J. Immunol. Methods 168 1994 49 54
24. S.L. Swain Helper T-cell differentiation Curr. Opin. Immunol. 11 1999 180 185
25. G. Trinchieri Interleukin-12 and the regulation of innate resistance and adaptive immunity Nat. Rev. Immunol. 3 2003 133 146
26. W.T. Watford, M. Moriguchi, A. Morinobu, and J.J. O'Shea The biology of IL-12: coordinating innate and adaptive immune responses Cytokine Growth Factor Rev. 14 2003 361 368
27. D. Xu, W.L. Chan, B.P. Leung, D. Hunter, K. Schulz, R.W. Carter, I.B. McInnes, J.H. Robinson, and F.Y. Liew Selective expression and functions of interleukin 18 receptor on T-helper (Th) type 1 but not Th2 cells J. Exp. Med. 188 1998 1485 1492
28. X. Yang, J. Gartner, L. Zhu, S. Wang, and R.C. Brunham IL-10 gene knockout mice show enhanced Th1-like protective immunity and absent granuloma formation following Chlamydia trachomatis lung infection J. Immunol. 162 1999 1010 1017