Prospective evaluation of intestinal homing memory T cells in ulcerative colitis

Inflammatory Bowel Diseases

Volumn 10, Issue 5, 2004, Pages 496-503

  Hart, A L ^a   Kamm, M A ^a   Knight, S C ^b   Stagg, A J ^b  

^a ST MARK S HOSPITAL   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

7 integrin; Intestinal homing; Itracellular cytokines; Lymphocyte; Ulcerative colitis

Indexed keywords

CD3 ANTIGEN; CD45 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; PROTEIN ANTIBODY; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ANTIBODY LABELING; ARTICLE; BLOOD ANALYSIS; CELL LABELING; CELL TRANSPORT; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DATA ANALYSIS; ENTERITIS; FEMALE; FLOW CYTOMETRY; FOLLOW UP; HUMAN; HUMAN CELL; HUMAN TISSUE; INTESTINE CELL; INTESTINE MUCOSA; LEUKOCYTE; LYMPHOCYTE HOMING; MALE; MEMORY CELL; MICROENVIRONMENT; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN ANALYSIS; RELAPSE; REMISSION; STATISTICAL SIGNIFICANCE; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH2 CELL; ULCERATIVE COLITIS;

ADULT; AGED; COLITIS, ULCERATIVE; FEMALE; FLOW CYTOMETRY; HUMANS; INFLAMMATION; INTERLEUKIN-4; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RECEPTORS, LYMPHOCYTE HOMING; RECURRENCE; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 4644292647     PISSN: 10780998     EISSN: None     Source Type: Journal    
DOI: 10.1097/00054725-200409000-00002     Document Type: Article

References (46)

1. Akazawa A, Sakaida I, Higaki S, et al. Increased expression of tumor necrosis factor-alpha messenger RNA in the intestinal mucosa of inflammatory bowel disease, particularly in patients with disease in the inactive phase. J Gastroenterol. 2002;37:345-353.
2. Fuss IJ, Neurath M, Boirivant M, et al. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J Immunol. 1996;157:1261-1270.
3. Ishiguro Y. Mucosal proinflammatory cytokine production correlates with endoscopic activity of ulcerative colitis. J Gastroenterol. 1999;34: 66-74.
4. Sawa Y, Oshitani N, Adachi K, et al. Comprehensive analysis of intestinal cytokine messenger RNA profile by real-time quantitative polymerase chain reaction in patients with inflammatory bowel disease. Int J Mol Med. 2003;11:175-179.
5. West GA, Matsuura T, Levine AD, et al. Interleukin 4 in inflammatory bowel disease and mucosal immune reactivity. Gastroenterology 1996; 110:1683-1695.
6. Boirivant M, Fuss IJ, Chu A, et al. Oxazolone colitis: A murine model of T helper cell type 2 colitis treatable with antibodies to interleukin 4. J Exp Med. 1998;188:1929-1939.
7. Butcher EC, Picker LJ. Lymphocyte homing and homeostasis. Science 1996;272:60-66.
8. Salmi M, Jalkanen S. Molecules controlling lymphocyte migration to the gut. Gut 1999;45:148-153.
9. Berlin C, Berg EL, Briskin MJ, et al. Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1. Cell 1993;74:185.
10. Erle DJ, Briskin MJ, Butcher EC, et al. Expression and function of the MAdCAM-1 receptor, integrin alpha 4 beta 7, on human leukocytes. J Immunol. 1994;153:517-528.
11. Hogg N, Berlin C. Structure and function of adhesion receptors in leukocyte trafficking. Immunol Today 1995;16:327-330.
12. Picker LJ. Mechanisms of lymphocyte homing. Curr Opin Immunol. 1992;4:277-286.
13. Schweighoffer T, Tanaka Y, Tidswell M, et al. Selective expression of integrin alpha 4 beta 7 on a subset of human CD4+ memory T cells with Hallmarks of gut-trophism. J Immunol. 1993;151:717-729.
14. Mackay CR, Andrew DP, Briskin M, et al. Phenotype, and migration properties of three major subsets of tissue homing T cells in sheep. Eur J Immunol. 1996;26:2433-2439.
15. Williams MB, Butcher EC. Homing of naive and memory T lymphocyte subsets to Peyer's patches, lymph nodes, and spleen. J Immunol. 1997; 159:1746-1752.
16. Rose JR, Williams MB, Rott LS, et al. Expression of the mucosal homing receptor alpha4beta7 correlates with the ability of CD8+ memory T cells to clear rotavirus infection. J Virol. 1998;72:726-730.
17. Rott LS, Rose JR, Bass D, et al. Expression of mucosal homing receptor alpha4beta7 by circulating CD4+ cells with memory for intestinal rotavirus. J Clin Invest. 1997;100:1204-1208.
18. Kantele A, Westerholm M, Kantele JM, et al. Homing potentials of circulating antibody-secreting cells after administration of oral or parenteral protein or polysaccharide vaccine in humans. Vaccine 1999;17:229-236.
19. Campbell DJ, Butcher EC. Rapid acquisition of tissue-specific homing phenotypes by CD4(+) T cells activated in cutaneous or mucosal lymphoid tissues. J Exp Med. 2002;195:135-141.
20. Stagg AJ, Kamm MA, Knight SC. Intestinal dendritic cells increase T cell expression of alpha4beta7 integrin. Eur J Immunol. 2002;32:1445-1454.
21. Schroeder KW, Tremaine WJ, Ilstrup DM. Coated oral 5-ammosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study. N Engl J Med. 1987;317:1625-1629.
22. North ME, Ivory K, Funauchi M, et al. Intracellular cytokine production by human CD4+ and CD8+ T cells from normal and immunodeficient donors using directly conjugated anti-cytokine antibodies and three-colour flow cytometry. Clin Exp Immunol. 1996; 105:517-522.
23. Jung T, Schauer U, Heusser C, et al. Detection of intracellular cytokines by flow cytometry. J Immunol Methods 1993;159:197-207.
24. Panoskaltsis N, Reid CD, Knight SC. Quantification and cytokine production of circulating lymphoid and myeloid cells in acute myelogenous leukaemia. Leukemia 2003;17:716-730.
25. Wagner N, Lohler J, Kunkel EJ, et al. Critical role for beta7 integrins in formation of the gut-associated lymphoid tissue. Nature 1996;382:366-370.
26. Jung T, Schauer U, Heusser C, et al. Detection of intracellular cytokines by flow cytometry. J Immunol Methods. 1993;159:197-207.
27. Inoue S, Matsumoto T, Iida M, et al. Characterization of cytokine expression in the rectal mucosa of ulcerative colitis: correlation with disease activity. Am J Gastroenterol. 1999;94:2441-2446.
28. Sartor RB. Cytokines in intestinal inflammation: pathophysiological and clinical considerations. Gastroenterology 1994; 106:533-539.
29. Camoglio L, Te Velde AA, Tigges AJ, et al. Altered expression of interferon-gamma and interleukin-4 in inflammatory bowel disease. Inflamm Bowel Dis. 1998;4:285-290.
30. Funakoshi K, Sugimura K, Sasakawa T, et al. Study of cytokines in ulcerative colitis. J Gastroenterol. 1995;30(Suppl 8):61-63.
31. Fuss IJ, Neurath M, Boirivant M, et al. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J Immunol. 1996;157:1261-1270.
32. Karttunnen R, Breese EJ, Walker-Smith JA, et al. Decreased mucosal interleukin-4 (IL-4) production in gut inflammation. J Clin Pathol. 1994; 47:1015-1018.
33. West GA, Matsuura T, Levine AD, et al. Interleukin 4 in inflammatory bowel disease and mucosal immune reactivity. Gastroenterology. 1996; 110:1683-1695.
34. Boirivant M, Fuss IJ, Chu A, et al. Oxazolone colitis: a murine model of T helper cell type 2 colitis treatable with antibodies to interleukin 4. J Exp Med. 1998;188:1929-1939.
35. Heller F, Fuss IJ, Nieuwenhuis EE, et al. Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells. Immunity 2002;17:629-638.
36. Fort M, Lesley R, Davidson N, et al. IL-4 exacerbates disease in a Th1 cell transfer model of colitis. J Immunol. 2001;166:2793-2800.
37. March SH, Lamkin VA, Savage MO, et al. Serum concentrations of tumour necrosis factor alpha in childhood chronic inflammatory bowel disease. Gut 1991;32:913-917.
38. Funakoshi K, Sugimura K, Sasakawa T, et al. Study of cytokines in ulcerative colitis. J Gastroenterol. 1995;30(Suppl 8):61-63.
39. Grottrup-Wolfers E, Moeller J, Karbach U, et al. Elevated cell-associated levels of interleukin 1 beta and interleukin 6 in inflamed mucosa of inflammatory bowel disease. Eur J Clin Invest. 1996;26:115-122.
40. Reimund JM, Wittersheim C, Dumont S, et al. Mucosal inflammatory cytokine production by intestinal biopsies in patients with ulcerative colitis and Crohn's disease. J Clin Immunol. 1996;16:144-150.
41. Sawa Y, Oshitani N, Adachi K, et al. Comprehensive analysis of intestinal cytokine messenger RNA profile by real-time quantitative polymerase chain reaction in patients with inflammatory bowel disease. Int J Mol Med. 2003;11:175-179.
42. Carty E, De Brabander M, Feakins RM, et al. Measurement of in vivo rectal mucosal cytokine and cicosanoid production in ulcerative colitis using filter paper. Gut 2000;46:487-492.
43. Ishiguro Y. Mucosal proinflammatory cytokine production correlates with endoscopic activity of ulcerative colitis. J Gastroenterol. 1999;34: 66-74.
44. Powrie F, Leach MW, Mauze S, et al. Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells. Immunity 1994;1:553-562.
45. Marth T, Strober W, Seder RA, et al. Regulation of transforming growth factor-beta production by interleukin-12. Eur J Immunol. 1997;27:1213-1220.
46. Stagg AJ, Kamm MA, Knight SC. Intestinal dendritic cells increase T cell expression of alpha4beta7 integrin. Eur J Immunol. 2002;32:1445-1454.