Postnatal maturation of cytochrome oxidase and lactate dehydrogenase activity and age-dependent consequences of lithium-pilocarpine status epilepticus in the rat: A regional histoenzymology study

Pediatric Research

Volumn 56, Issue 4, 2004, Pages 647-655

  Raffo, Emmanuel ^a   Koning, Estelle ^a   Nehlig, Astrid ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C OXIDASE; DEOXYGLUCOSE; LACTATE DEHYDROGENASE; LITHIUM; PILOCARPINE;

ADOLESCENT; AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CITRIC ACID CYCLE; CONTROLLED STUDY; ENTORHINAL CORTEX; ENZYME ACTIVITY; EPILEPTIC STATE; FEMALE; GLUCOSE BRAIN LEVEL; GLUCOSE METABOLISM; GLUCOSE UTILIZATION; GLYCOLYSIS; HIPPOCAMPUS; MALE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; RAT; SENSORIMOTOR CORTEX; TEMPORAL LOBE EPILEPSY; THALAMUS;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; BRAIN; ELECTRON TRANSPORT COMPLEX IV; FEMALE; GLUCOSE; L-LACTATE DEHYDROGENASE; LITHIUM; MALE; MUSCARINIC AGONISTS; PILOCARPINE; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; STATUS EPILEPTICUS;

EID: 4644280381     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/01.PDR.0000139604.47609.8C     Document Type: Article

References (60)

1. Camfield P, Camfield C, Gordon K, Dooley J 1994 What types of epilepsy are preceded by febrile seizures? A population-based study of children. Dev Med Child Neural 36:887-892
2. French JA, Williamson PD, Thadani VM, Darcey TM, Mattson RH, Spencer SS, Spencer DD 1993 Characteristics of medial temporal lobe epilepsy: I. Results of history and physical examination. Ann Neurol 34:774-780
3. Mathern GW, Kuhlman PA, Mendoza D, Pretorius JK 1997 Human fascia dentate anatomy and hippocampal neuron densities differ depending on the epileptic syndrome and age at first seizures. J Neuropathol Exp Neurol 56:199-212
4. Turski L, Ikonomidou C, Turski WA, Bortolotto ZA, Cavalheiro EA 1989 Review: Cholinergic mechanisms and epileptogenesis. The seizures induced by pilocarpine: a novel experimental model of intractable epilepsy. Synapse 3:154-171
5. Dubé C, Marescaux C, Nehlig A 2000 A metabolic and neuropathological approach to the understanding of plastic changes occurring in the immature and adult rat brain during lithium-pilocarpine induced epileptogenesis. Epilepsia 41:S36-S43
6. Cavalheiro EA, Silva DF, Turski WA, Calderazzo-Filho LS, Bortolotto ZA, Turski L 1987 The susceptibility of rats to pilocarpine-induced seizures is age-dependent. Dev Brain Res 465:43-58
7. Dubé C, Boyet S, Marescaux C, Nehlig A 2001 Relationship between neuronal loss and interictal metabolism during the chronic phase of the lithium-pilocarpine model of epilepsy in the immature and adult rat. Exp Neurol 167:227-241
8. Nehlig A, Pereira de Vasconcelos AP, Boyet S 1988 Quantitative autoradiographic measurement of local cerebral glucose utilization in freely moving rats during postnatal development. J Neurosci 8:2321-2333
9. Fernandes MJ, Dubé C, Boyet S, Marescaux C, Nehlig A 1999 Correlation between hypermetabolism and neuronal damage during status epilepticus induced by lithium and pilocarpine in immature and adult rats. J Cereb Blood Flow Metab 19:195-209
10. Vannucci SJ 1994 Developmental expression of GLUT1 and GLUT3 glucose transporters in rat brain. J Neurochem 62:240-246
11. Dubé C, Boyet S, Marescaux C, Nehlig A 2000 Progressive metabolic changes underlying the chronic reorganization of brain circuits during the silent phase of the lithium-pilocarpine model of epilepsy in the immature and adult rat. Exp Neurol 162:146-157
12. Borowsky IW, Collins RC 1989 Metabolic anatomy of brain: a comparison of regional capillary density, glucose metabolism, and enzyme activities. J Comp Neurol 288:401-413
13. 14C]cyanide tissue labeling in vivo. J Cereb Blood Flow Metab 6:8-14
14. Dufour F, Koning E, Nehlig A 2003 Basal levels of metabolic activity are elevated in Genetic Absence Epilepsy Rats from Strasbourg (GAERS): measurement of regional activity of cytochrome oxidase and lactate dehydrogenase by histochemistry. Exp Neurol 182:346-352
15. Hevner RF, Liu S, Wong-Riley MT 1995 A metabolic map of cytochrome oxidase in the rat brain: histochemical, densitometric and biochemical studies. Neuroscience 65:313-342
16. Wong-Riley MT 1989 Cytochrome oxidase: an endogenous metabolic marker for neuronal activity. Trends Neurosci 12:94-101
17. Bilger A, Nehlig A 1991 Quantitative histochemical changes in enzymes involved in energy metabolism in the rat brain during postnatal development. I. Cytochrome oxidase and lactate dehydrogenase. Int J Dev Neurosci 9:545-553
18. Curti D, Giangare MC, Redolfi ME, Fugaccia I, Benzi G 1990 Age-related modifications of cytochrome c oxidase activity in discrete brain regions. Mech Ageing Dev 55:171-180
19. Gonzalez-Pardo H, Novelli A, Menendez-Patterson A, Arias JL 1996 The development of oxidative metabolism in diencephalic structures of the rat: a quantitative study. Brain Res Bull 41:31-38
20. Hovda DA, Villablanca JR 1998 Cerebral metabolism following neonatal or adult hemidecortication in cats: effect on oxidative capacity using cytochrome oxidase histochemistry. Brain Res Dev Brain Res 110:39-50
21. Tuor UI, Kurpita G, Simone C 1994 Correlation of local changes in cerebral blood flow, capillary density, and cytochrome oxidase during development. J Comp Neurol 342:439-448
22. Jacobsen NO 1969 The histochemical localization of lactic dehydrogenase isoenzymes in the rat nephron by means of an improved polyvinyl alcohol method. Histochemie 20:250-265
23. Paxinos G, Watson C 1986 The Rat Brain in Stereotaxic Coordinates. Academic Press, New York
24. Rosa MG, Gattass R, Soares JG 1991 A quantitative analysis of cytochrome oxidase-rich patches in the primary visual cortex of Cebus monkeys: topographic distribution and effects of late monocular enucleation. Exp Brain Res 84:195-209
25. Wong-Riley M, Carroll EW 1984 Effect of impulse blockage on cytochrome oxidase activity in monkey visual system. Nature 307:262-264
26. Borowsky IW, Collins RC 1989 Histochemical changes in enzymes of energy metabolism in the dentate gyrus accompany deafferentation and synaptic reorganization. Neuroscience 33:253-262
27. Villablanca JR, Schmanke TD, Hovda DA 1999 Effects of a restricted unilateral neocortical lesion upon cerebral glucose and oxidative metabolisms in fetal and neonatal cats. Brain Res Dev Brain Res 117:1-13
28. Wong-Riley MT, Welt C 1980 Histochemical changes in cytochrome oxidase of cortical barrels after vibrissal removal in neonatal and adult mice. Proc Natl Acad Sci USA 77:2333-2337
29. Dietrich WD, Durnham D, Lowry OH, Woolsey TA 1982 "Increased" sensory stimulation leads to changes in energy-related enzymes in the brain. J Neurosci 2:1608-1613
30. Klein B, Kuschirisky W, Schröck H, Vetterlein F 1986 Interdependency of local capillary density, blood flow, and metabolism in rat brains. Am J Physiol 251:H1333-H1340
31. Sokoloff L 1982 The radioactive deoxyglucose method. Theory, procedure, and applications for the measurement of local glucose utilization in the central nervous system. In: Agranoff BW, Aprison MH (eds) Advances in Neurochemistry, Vol IV. Plenum, New York, pp 1-82
32. 14C]2-deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem 28:897-916
33. Booth RF, Patel TB, Clark JB 1980 The development of enzymes of energy metabolism in the brain of a precocial (guinea pig) and non precocial (rat) species. J Neurochem 34:17-25
34. Leong SF, Clark JB 1984 Regional enzyme development in rat brain. Enzymes associated with glucose utilization. Biochem J 218:131-138
35. Leong SF, Clark JB 1984 Regional enzyme development in rat brain. Enzymes of energy metabolism. Biochem J 218:139-145
36. Takagaki G 1974 Developmental changes in glycolysis in rat cerebral cortex. J Neurochem 23:479-487
37. Bonavita V 1964 Molecular evolution of lactate dehydrogenase in the developing nervous tissue. Progr Brain Res 4:254-272
38. Bonavita V, Ponte F, Amore G 1962 Lactate dehydrogenase isozymes in the developing rat brain. Nature 196:576-577
39. Ford DH 1973 Selected maturational changes observed in the postnatal rat brain. Progr Brain Res 40:1-12
40. Hamburg M, Flexner LB 1957 Biochemical and physiological differentiation during morphogenesis. XXI. Effect of hypothyroidism and hormone therapy on enzyme activities of the developing cerebral cortex of the rat. J Neurochem 1:279-288
41. Klee CB, Sokoloff L 1967 Changes in D(-)-β-hydroxybutyrate dehydrogenase activity during brain maturation of the rat. J Biol Chem 242:3880-3883
42. Murakami DM, Fuller CA 1988 The postnatal development of oxidative metabolism in the suprachiasmatic nucleus of the rat. Neuroscience 24:977-986
43. Pysh JJ 1970 Mitochondrial changes in rat inferior colliculus during postnatal development: an electron microscopic study. Brain Res 18:325-342
44. Almeida A, Brooks KJ, Sammut I, Keelan J, Davey GP, Clark JB, Bates TE 1995 Postnatal development of the complexes of the electron transport chain in synaptic mitochondria from rat brain. Dev Neurosci 17:212-218
45. Roch C, Leroy C, Nehlig A, Namer IJ 2002 Magnetic resonance imaging in the study of the lithium-pilocarpine model of temporal lobe epilepsy in adult rats. Epilepsia 43:325-335
46. Roch C, Leroy C, Nehlig A, Namer IJ 2002 Predictive value of cortical injury for development of temporal lobe epilepsy in 21-day-old rats: an MRI approach using the lithium-pilocarpine model. Epilepsia 43:1129-1136
47. Kubova H, Druga R, Lukasiuk K, Suchomelova L, Haugvicova R, Jirmanova I, Pitkanen A 2001 Status epilepticus causes necrotic damage in the mediodorsal nucleus of the thalamus in immature rats. J Neurosci 21:3593-3529
48. Pineau N, Charriaut-Marlangue C, Motte J, Nehlig A 1999 Pentylenetetrazol seizures induce cell suffering but not death in the immature rat brain. Brain Res Dev Brain Res 112:139-144
49. Bevan MD, Smith AD, Bolam JP 1996 The substantia nigra as a site of synaptic integration of functionally diverse information arising from the ventral pallidum and the globus pallidus in the rat. Neuroscience 75:5-12
50. Calabresi P, De Murtas M, Bernardi G 1997 The neostriatum beyond the motor function: experimental and clinical evidence. Neuroscience 78:39-60
51. Depaulis A, Vergnes M, Marescaux C 1994 Endogenous control of epilepsy: the nigral inhibitory system. Progr Neurobiol 42:33-52
52. Deransart C, Vercueil L, Marescaux C, Depaulis A 1998 The role of basal ganglia in the control of generalized absence seizures. Epilepsy Res 32:213-223
53. Garant DS, Gale K 1987 Substantia nigra-mediated aniiconvulsant actions: role of nigral output pathways. Exp Neurol 97:143-159
54. Cavalheiro EA, Turski L 1986 Intrastriatal N-methyl-D-aspartate prevents amygdala kindled seizures in rats. Brain Res 377:173-176
55. Löscher W, Czuczwar SJ, Jäkel R, Schwarz M 1987 Effects of microinjections of gamma-vinyl GABA or isoniazid into substantia nigra on the development of amygdala kindling in rats. Exp Neurol 95:622-638
56. Paz C, Gutiérrez-Baeza F, Bazán-Perkins B 1991 Transaction of the superior cerebellar peduncle interferes with the onset and duration of generalized seizures induced by amygdaloid kindling. Brain Res 558:90-92
57. Miller JW, Gray BC, Turner GM 1993 Role of the fastigial nucleus in generalized seizures as demonstrated by GABA agonist microinjections. Epilepsia 34:973-978
58. Cooper IS, Riklan M, Amin I, Cullinan T 1978 A long-term follow-up study of cerebellar stimulation for the control of epilepsy. In: Cooper IS (ed) Cerebellar Stimulation in Man. Raven Press, New York, pp 19-38
59. Turner DA, Buhl EH, Hailer NP, Nitsch R 1998 Morphological features of the entorhinal-hippocampal connection. Progr Neurobiol 55:537-562
60. Magistretti PJ, Pellerin L 1996 Cellular bases of brain energy metabolism and their relevance to functional brain imaging: evidence for a prominent role of astrocytes. Cerebral Cortex 6:50-61