Human fascia dentata anatomy and hippocampal neuron densities differ depending on the epileptic syndrome and age at first seizure

Journal of Neuropathology and Experimental Neurology

Volumn 56, Issue 2, 1997, Pages 199-212

  Mathern, Gary W ^a,b   Kuhlman, Paula A ^b   Mendoza, Delia ^b   Pretorius, James K ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Complex partial; Development; NIH image; Pediatric; Seizures

Indexed keywords

ARTICLE; CELL DENSITY; CLINICAL ARTICLE; COMPLEX PARTIAL SEIZURE; DENTATE GYRUS; DISEASE CLASSIFICATION; EPILEPSY; GRANULE CELL; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL;

EID: 0030780112     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199702000-00011     Document Type: Article

References (45)

1. Sommer W. Erkrankung des ammonshorns als aetiologisches moment der epilepsie. Arch Psychiatr Nervenkr 1880;10:631-75
2. Bratz E. Ammonshornbefunde bei epileptikern. Arch Psychiat Nervenkr 1899;32:820-35
3. Stauder KH. Epilepsie und schlafenlappen. Arch Psychiatr Nervenkr 1936;104:181-211
4. Margerison JH, Corsellis JAN. Epilepsy and the temporal lobes. Brain 1966;89:499-530
5. Babb TL, Brown WJ. Pathological findings in epilepsy. In: Engel Jr. J, ed. Surgical treatment of the epilepsies. New York: Raven Press, 1987:511-40
6. Mathern GW, Babb TL, Vickrey BG, Melendez M, Pretorius JK. The clinical-pathogenic mechanisms of hippocampal neuron loss and surgical outcomes in temporal lobe epilepsy. Brain 1995;118: 105-13
7. Falconer MA, Taylor DC. Surgical treatment of drug-resistant epilepsy due to mesial temporal sclerosis. Etiology and significance. Arch Neurol 1968;19:353-61
8. Meldrum BS, Corsellis JAN. Epilepsy. In: Adams JH, Corsellis JAN, Duchen LW, eds. Greenfield's neuropathology. London: John Wiley & Sons, 1984:921-50
9. Sagar HJ, Oxbury JM. Hippocampal neuron loss in temporal lobe epilepsy: Correlation with early childhood convulsions. Ann Neurol 1987;22:334-40
10. Bruton CJ. The neuropathology of temporal lobe epilepsy. New York: Oxford University Press, 1988
11. Spielmeyer W. Die pathogenese des epileptischen krampfes. Z Gesamte Neurol Psychiatr 1927;109:501-20
12. Scholz W. Die krampfschädigungen des gehirns. Berlin: Springer-Verlag, 1951
13. Peiffer J. Morphologische aspekte der epilepsien. Berlin: Springer, 1963
14. Mouritzen-Dam A. Epilepsy and neuron loss in the hippocampus. Epilepsia 1980;21:617-29
15. Cavazos JE, Golarai G, Sutula TP. Mossy fiber synaptic reorganization induced by kindling: Time course of development, progression, and permanence. J Neurosci 1991;11:2795-2803
16. Cavazos JE, Das I, Sutula TP. Neuronal loss induced in limbic pathways by kindling: Evidence for induction of hippocampal sclerosis by repeated brief seizures. J Neurosci 1994;14:3106-21
17. Sutula TP, Cavazos JE, Woodard AR. Long-term structural and functional alterations induced in the hippocampus by kindling: Implications for memory dysfunction and the development of epilepsy. Hippocampus 1994;4:254-58
18. Nelson KB, Ellenberg JH. Predictors of epilepsy in children who have experienced febrile seizures. N Engl J Med 1976;295:1029-33
19. Annegers JF, Hauser WA, Elveback LR. Remission of seizures and relapse in patients with epilepsy. Epilepsia 1979;20:729-37
20. Verity CM, Ross EM, Golding J. Outcome of childhood status epilepticus and lengthy febrile convulsions: Findings of national cohort study. BMJ 1993;307:225-28
21. Camfield P, Camfield C, Gordon K, Dooley J. What types of epilepsy are preceded by febrile seizures? A population-based study of children. Dev Med Child Neurol 1994;36:887-92
22. Engel Jr J, Levesque M, Crandall PH, Shewman A, Rausch R, Sutherling W. The epilepsies. In: Grossman RG, ed. Principals of neurosurgery. New York: Raven Press, 1991:319-58
23. Mathern GW, Pretorius JK, Babb TL. Quantified patterns of mossy fiber sprouting and neuron densities in hippocampal and lesional seizures. J Neurosurg 1995;82:211-19
24. Mathern GW, Babb TL, Pretorius JK, Leite JP. Reactive synaptogenesis and neuron densities for neuropeptide Y, somatostatin, and glutamate decarboxylase immunoreactivity in the epileptogenic human fascia dentata. J Neurosci 1995;15:3990-4004
25. Mathern GW, Babb TL, Mischel PS, et al. Childhood generalized and mesial temporal epilepsies demonstrate different amounts and patterns of hippocampal neuron loss and mossy fiber synaptic reorganization. Brain 1996;119:965-987
26. Mathern GW, Leite JP, Pretorius JK, Quinn B, Peacock WJ, Babb TL. Children with severe epilepsy: Evidence of hippocampal neuron losses and aberrant mossy fiber sprouting during postnatal granule cell migration and differentiation. Dev Brain Res 1994;78:70-80
27. Weiser HG, Engel J Jr, Williamson PD, Babb TL, Gloor P. Surgically remediable temporal lobe syndromes. In: Engel Jr. J, ed. Surgical treatment of the epilepsies, 2nd ed. New York: Raven Press, 1993:49-63
28. Babb TL, Lieb JP, Brown WJ, Pretorius J, Crandall PH, Distribution of pyramidal cell density and hyperexcitability in the epileptic human hippocampus. Epilepsia 1984;25:721-28
29. Babb TL, Brown WJ, Pretorius J, Davenport C, Lieb JP, Crandall PH. Temporal lobe volumetric cell densities in temporal lobe epilepsy. Epilepsia 1984;25:729-40
30. Mathern GW, Babb TL, Pretorius JK, Melendez M, Lévesque MF. The relationships between clinical features, lesion pathology, and hippocampal neuron losses in temporal lobe epilepsy. Epilepsy Res 1995;21:133-47
31. Mathern GW, Armstrong DL, Babb TL, Hippocampal sclerosis. In. Engel Jr. J, Pedley TA, eds. Epilepsy: A compreshensive textbook. New York: Raven Press. Forthcoming.
32. Abercrombie M. Estimation of nuclear population from microtome sections. Anat Rec 1946;94:239-47
33. Lorente de Nó R. Studies on the structure of the cerebral cortex. II. Continuation of the study of the ammonic system. J Psychologie und Neurologie 1934;45:113-77
34. Amaral DG, Campbell. Transmitter systems in the primate dentate gyrus. Human Neurobiol 5:169-80
35. Cruz-Orive LM, Weibel ER. Recent stereological methods for cell biology: A brief survey. Am J Physiol 1990;258:L148-56
36. Mayhew TM. A review of recent advances in stereology for quantifying neural structures. J Neurocytol 1992;21:313-28
37. West MJ. Stereological studies of the hippocampus: A comparison of the hippocampal subdivisions of diverse species including hedgehogs, laboratory rodents, wild mice and men. Prog Brain Res Elsevier, 1990;83:13-36
38. Coggeshall RE, Lekan HA. Methods for determining numbers of cells and synapses: A case for more uniform standards of review. J Comp Neuol 1996;364:6-15
39. Saper CB. Any way you cut it: A new journal policy for the use of unbiased counting methods. (Editorial) J Comp Neurol 1996;364:5
40. Houser CR. Granule cell dispersion in the dentate gyrus of humans with temporal lobe epilepsy. Brain Res 1990;535:195-204
41. Houser CR, Swartz BE, Walsh GO, Delgado-Escueta AV. Granule cell disorganization in the dentate gyrus: Possible alterations of neuronal migration in human temporal lobe epilepsy. In: Engel Jr. J, Wasterlain C, Cavalheiro EA, Heinemann U, Avanzini G, eds. Molecular neurobiology of epilepsy. Amsterdam: Elsevier Science, 1992:41-49
42. Mello LEAM, Cavalheiro EA, Tan AM, Pretorius JK, Babb TL, Finch DM. Granule cell dispersion in relation to mossy fiber sprouting, hippocampal cell loss, silent period and seizure frequency in the pilocarpine model of epilepsy. In: Engel Jr J, Wasterlain C, Cavalheiro EA, Heinemann U, Avanzini G, eds. Molecular neurobiology of epilepsy. Amsterdam: Elsevier Science, 1992:51-60
43. Mello LEAM, Cavalheiro EA, Tan AM, et al. Circuit mechanisms of seizures in the pilocarpine model of chronic epilepsy: Cell loss and mossy fiber sprouting. Epilepsia 1993;34:985-95
44. Bertram EH, Lothman EW. Morphometric effects of intermittent kindled seizures and limbic status epilepticus in the dentate gyrus of the rat. Brain Res 1993;603:25-31
45. Watanabe Y, Johnson RS, Butler LS, et al. Null mutation of c-fos impairs structural and functional plasticities in the kindling model of epilepsy. J Neurosci 1996;16:3827-36