메뉴 건너뛰기




Volumn 182, Issue 2, 2003, Pages 346-352

Basal levels of metabolic activity are elevated in Genetic Absence Epilepsy Rats from Strasbourg (GAERS): Measurement of regional activity of cytochrome oxidase and lactate dehydrogenase by histochemistry

Author keywords

Absence epilepsy; Cytochrome oxidase; Glucose metabolism; Histochemistry; Lactate dehydrogenase; Seizures; Spike and wave discharges

Indexed keywords

CARBON 14; CYTOCHROME C OXIDASE; DEOXYGLUCOSE; GLUCOSE; LACTATE DEHYDROGENASE; TRICARBOXYLIC ACID;

EID: 0042164621     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4886(03)00052-9     Document Type: Article
Times cited : (19)

References (44)
  • 1
    • 0026314724 scopus 로고
    • Quantitative histochemical changes in enzymes involved in energy metabolism in the rat brain during postnatal development. I. Cytochrome oxidase and lactate dehydrogenase
    • Bilger A., Nehlig A. Quantitative histochemical changes in enzymes involved in energy metabolism in the rat brain during postnatal development. I. Cytochrome oxidase and lactate dehydrogenase. Int. J. Dev. Neurosci. 9:1991;545-553.
    • (1991) Int. J. Dev. Neurosci. , vol.9 , pp. 545-553
    • Bilger, A.1    Nehlig, A.2
  • 2
    • 0026710810 scopus 로고
    • Intracranial blood flow velocities during seizures and generalized epileptic discharges
    • Bode H. Intracranial blood flow velocities during seizures and generalized epileptic discharges. Eur. J. Pediatr. 151:1992;706-709.
    • (1992) Eur. J. Pediatr. , vol.151 , pp. 706-709
    • Bode, H.1
  • 3
    • 0024450787 scopus 로고
    • Metabolic anatomy of the brain: A comparison of regional capillary density, glucose metabolism, and enzyme activities
    • Borowsky I.W., Collins R.C. Metabolic anatomy of the brain a comparison of regional capillary density, glucose metabolism, and enzyme activities . J. Comp. Neurol. 288:1989;401-413.
    • (1989) J. Comp. Neurol. , vol.288 , pp. 401-413
    • Borowsky, I.W.1    Collins, R.C.2
  • 4
    • 0024819462 scopus 로고
    • Histochemical changes in enzymes of energy metabolism in the dentate gyrus accompany deafferentation and synaptic reorganization
    • Borowsky I.W., Collins R.C. Histochemical changes in enzymes of energy metabolism in the dentate gyrus accompany deafferentation and synaptic reorganization. Neuroscience. 33:1989;253-262.
    • (1989) Neuroscience , vol.33 , pp. 253-262
    • Borowsky, I.W.1    Collins, R.C.2
  • 5
    • 0000202516 scopus 로고    scopus 로고
    • Circulation and energy metabolism of the brain
    • G.J. Siegel, B.W. Agranoff, R.W. Albers, S.K. Fisher, & M.D. Uhler. Philadelphia: Lippincott-Raven
    • Clarke D.D., Sokoloff L. Circulation and energy metabolism of the brain. Siegel G.J., Agranoff B.W., Albers R.W., Fisher S.K., Uhler M.D. Basic Neurochemistry. Molecular, Cellular and Medical Aspects. Sixth ed. 1999;637-689 Lippincott-Raven, Philadelphia.
    • (1999) Basic Neurochemistry. Molecular, Cellular and Medical Aspects Sixth Ed. , pp. 637-689
    • Clarke, D.D.1    Sokoloff, L.2
  • 6
    • 0025006293 scopus 로고
    • Age-related modifications of cytochrome c oxidase activity in discrete brain regions
    • Curti D., Giangare M.C., Redolfi M.E., Fugaccia I., Benzi G. Age-related modifications of cytochrome c oxidase activity in discrete brain regions. Mech. Ageing Dev. 55:1990;171-180.
    • (1990) Mech. Ageing Dev. , vol.55 , pp. 171-180
    • Curti, D.1    Giangare, M.C.2    Redolfi, M.E.3    Fugaccia, I.4    Benzi, G.5
  • 9
    • 0020364320 scopus 로고
    • "Increased" sensory stimulation leads to changes in energy-related enzymes in the brain
    • Dietrich W.D., Durnham D., Lowry O.H., Woolsey T.A. "Increased" sensory stimulation leads to changes in energy-related enzymes in the brain. J. Neurosci. 2:1982;1608-1613.
    • (1982) J. Neurosci. , vol.2 , pp. 1608-1613
    • Dietrich, W.D.1    Durnham, D.2    Lowry, O.H.3    Woolsey, T.A.4
  • 11
    • 0035577692 scopus 로고    scopus 로고
    • Metabolic approach of absence seizures in a genetic model of absence epilepsy, the GAERS: Study of the leucine-glutamate cycle
    • Dufour F., Nalecz K.A., Nalecz M.J., Nehlig A. Metabolic approach of absence seizures in a genetic model of absence epilepsy, the GAERS study of the leucine-glutamate cycle . J. Neurosci. Res. 66:2001;923-930.
    • (2001) J. Neurosci. Res. , vol.66 , pp. 923-930
    • Dufour, F.1    Nalecz, K.A.2    Nalecz, M.J.3    Nehlig, A.4
  • 12
    • 0033780707 scopus 로고    scopus 로고
    • Specific alteration in the expression of glial fibrillary acidic protein, glutamate dehydrogenase, glutamine synthetase in rats with genetic absence epilepsy
    • Dutuit M., Didier-Bazes M., Vergnes M., Mutin M., Conjard A., Akaoka H., Belin M.F., Touret M. Specific alteration in the expression of glial fibrillary acidic protein, glutamate dehydrogenase, glutamine synthetase in rats with genetic absence epilepsy. Glia. 32:2000;15-24.
    • (2000) Glia , vol.32 , pp. 15-24
    • Dutuit, M.1    Didier-Bazes, M.2    Vergnes, M.3    Mutin, M.4    Conjard, A.5    Akaoka, H.6    Belin, M.F.7    Touret, M.8
  • 13
    • 0036326330 scopus 로고    scopus 로고
    • Decreased expression of glutamate transporter in genetic absence epilepsy rats before seizure occurrence
    • Dutuit M., Touret M., Szymocha R., Nehlig A., Belin M.F., Didier-Bazes M. Decreased expression of glutamate transporter in genetic absence epilepsy rats before seizure occurrence. J. Neurochem. 80:2002;1029-1038.
    • (2002) J. Neurochem. , vol.80 , pp. 1029-1038
    • Dutuit, M.1    Touret, M.2    Szymocha, R.3    Nehlig, A.4    Belin, M.F.5    Didier-Bazes, M.6
  • 14
    • 0019993938 scopus 로고
    • Patterns of human local cerebral glucose metabolism during epileptic seizures
    • Engel J. Jr., Kuhl D.E., Phelps M.E. Patterns of human local cerebral glucose metabolism during epileptic seizures. Science. 218:1982;64-66.
    • (1982) Science , vol.218 , pp. 64-66
    • Engel J., Jr.1    Kuhl, D.E.2    Phelps, M.E.3
  • 15
    • 0021998492 scopus 로고
    • Local cerebral metabolic rate for glucose during petit mal absences
    • Engel J. Jr., Lubens P., Kuhl D.E., Phelps M.E. Local cerebral metabolic rate for glucose during petit mal absences. Ann. Neurol. 17:1985;121-128.
    • (1985) Ann. Neurol. , vol.17 , pp. 121-128
    • Engel J., Jr.1    Lubens, P.2    Kuhl, D.E.3    Phelps, M.E.4
  • 16
    • 0023959062 scopus 로고
    • Metabolic correlates of diffuse EEG spike-and-wave and absence seizures
    • Engel J. Jr., Lubens P., Phelps M.E. Metabolic correlates of diffuse EEG spike-and-wave and absence seizures. Ann. Neurol. 23:1988;207-208.
    • (1988) Ann. Neurol. , vol.23 , pp. 207-208
    • Engel J., Jr.1    Lubens, P.2    Phelps, M.E.3
  • 18
    • 0029795187 scopus 로고    scopus 로고
    • The development of oxidative metabolism in diencephalic structures of the rat: A quantitative study
    • Gonzalez-Pardo H., Novelli A., Menendez-Patterson A., Arias J.L. The development of oxidative metabolism in diencephalic structures of the rat a quantitative study . Brain Res. Bull. 41:1996;31-38.
    • (1996) Brain Res. Bull. , vol.41 , pp. 31-38
    • Gonzalez-Pardo, H.1    Novelli, A.2    Menendez-Patterson, A.3    Arias, J.L.4
  • 20
    • 0028883121 scopus 로고
    • A metabolic map of cytochrome oxidase in the rat brain: Histochemical, densitometric and biochemical studies
    • Hevner R.F., Liu S., Wong-Riley M.T.T. A metabolic map of cytochrome oxidase in the rat brain histochemical, densitometric and biochemical studies . Neuroscience. 65:1995;313-342.
    • (1995) Neuroscience , vol.65 , pp. 313-342
    • Hevner, R.F.1    Liu, S.2    Wong-Riley, M.T.T.3
  • 21
    • 0032505077 scopus 로고    scopus 로고
    • Cerebral metabolism following neonatal or adult hemidecortication in cats: Effect on oxidative capacity using cytochrome oxidase histochemistry
    • Hovda D.A., Villablanca J.R. Cerebral metabolism following neonatal or adult hemidecortication in cats effect on oxidative capacity using cytochrome oxidase histochemistry . Dev. Brain Res. 110:1998;39-50.
    • (1998) Dev. Brain Res. , vol.110 , pp. 39-50
    • Hovda, D.A.1    Villablanca, J.R.2
  • 22
    • 0033964502 scopus 로고    scopus 로고
    • Glial glutamate transporter mRNAs in the genetically absence epilepsy rat from Strasbourg
    • Ingram E.M., Tessler S., Bowery N.G., Emson P.C. Glial glutamate transporter mRNAs in the genetically absence epilepsy rat from Strasbourg. Mol. Brain Res. 75:2000;96-104.
    • (2000) Mol. Brain Res. , vol.75 , pp. 96-104
    • Ingram, E.M.1    Tessler, S.2    Bowery, N.G.3    Emson, P.C.4
  • 23
    • 0014621601 scopus 로고
    • The histochemical localization of lactic dehydrogenase isoenzymes in the rat nephron by means of an improved polyvinyl alcohol method
    • Jacobsen N.O. The histochemical localization of lactic dehydrogenase isoenzymes in the rat nephron by means of an improved polyvinyl alcohol method. Histochemie. 20:1969;250-265.
    • (1969) Histochemie , vol.20 , pp. 250-265
    • Jacobsen, N.O.1
  • 24
    • 0019918228 scopus 로고
    • Histochemical localization of cytochrome oxidase in the hippocampus: Correlation with specific neuronal types and afferent pathways
    • Kageyama G.H., Wong-Riley M.T.T. Histochemical localization of cytochrome oxidase in the hippocampus correlation with specific neuronal types and afferent pathways . Neuroscience. 7:1982;2337-2361.
    • (1982) Neuroscience , vol.7 , pp. 2337-2361
    • Kageyama, G.H.1    Wong-Riley, M.T.T.2
  • 25
    • 0023005833 scopus 로고
    • Interdependency of local capillary density, blood flow, and metabolism in rat brains
    • Klein B., Kuschinsky W., Schröck H., Vetterlein F. Interdependency of local capillary density, blood flow, and metabolism in rat brains. Am. J. Physiol. 251:1986;H1333-H1340.
    • (1986) Am. J. Physiol. , vol.251
    • Klein, B.1    Kuschinsky, W.2    Schröck, H.3    Vetterlein, F.4
  • 26
    • 0035213546 scopus 로고    scopus 로고
    • Relationship of spikes, synaptic activity, and local changes of cerebral blood flow
    • Lauritzen M. Relationship of spikes, synaptic activity, and local changes of cerebral blood flow. J. Cereb. Blood Flow Metabol. 21:2001;1367-1383.
    • (2001) J. Cereb. Blood Flow Metabol. , vol.21 , pp. 1367-1383
    • Lauritzen, M.1
  • 27
    • 0024215686 scopus 로고
    • Relationship between synaptogenesis and cytochrome oxidase activity in Purkinge cells of the developing rat cerebellum
    • Mjaatvedt A.E., Wong-Riley M.T.T. Relationship between synaptogenesis and cytochrome oxidase activity in Purkinge cells of the developing rat cerebellum. J. Comp. Neurol. 277:1982;155-182.
    • (1982) J. Comp. Neurol. , vol.277 , pp. 155-182
    • Mjaatvedt, A.E.1    Wong-Riley, M.T.T.2
  • 28
    • 0025977432 scopus 로고
    • Local cerebral glucose utilization in rats with petit mal-like seizures
    • Nehlig A., Vergnes M., Marescaux C., Boyet S., Lannes B. Local cerebral glucose utilization in rats with petit mal-like seizures. Ann. Neurol. 29:1991;72-77.
    • (1991) Ann. Neurol. , vol.29 , pp. 72-77
    • Nehlig, A.1    Vergnes, M.2    Marescaux, C.3    Boyet, S.4    Lannes, B.5
  • 29
    • 0026611820 scopus 로고
    • Mapping of cerebral energy metabolism in rats with genetic generalized nonconvulsive epilepsy
    • Nehlig A., Vergnes M., Marescaux C., Boyet S. Mapping of cerebral energy metabolism in rats with genetic generalized nonconvulsive epilepsy. J. Neural Transm. 35:(Suppl.):1992;1-8.
    • (1992) J. Neural Transm. , vol.35 , Issue.SUPPL. , pp. 1-8
    • Nehlig, A.1    Vergnes, M.2    Marescaux, C.3    Boyet, S.4
  • 30
    • 0027202646 scopus 로고
    • Cerebral energy metabolism in rats with genetic absence epilepsy is not correlated with the pharmacological increase or suppression of spike-wave discharges
    • Nehlig A., Vergnes M., Marescaux C., Boyet S. Cerebral energy metabolism in rats with genetic absence epilepsy is not correlated with the pharmacological increase or suppression of spike-wave discharges. Brain Res. 618:1993;1-8.
    • (1993) Brain Res. , vol.618 , pp. 1-8
    • Nehlig, A.1    Vergnes, M.2    Marescaux, C.3    Boyet, S.4
  • 33
    • 0025801711 scopus 로고
    • A quantitative analysis of cytochrome oxidase-rich patches in the primary visual cortex of Cebus monkeys: Topographic distribution and effects of late monocular enucleation
    • Rosa M.G.P., Gattass R., Soares J.G.M. A quantitative analysis of cytochrome oxidase-rich patches in the primary visual cortex of Cebus monkeys topographic distribution and effects of late monocular enucleation . Exp. Brain Res. 84:1991;195-209.
    • (1991) Exp. Brain Res. , vol.84 , pp. 195-209
    • Rosa, M.G.P.1    Gattass, R.2    Soares, J.G.M.3
  • 34
    • 0023932434 scopus 로고
    • Changes in blood flow in the middle cerebral artery during absence seizures
    • Sanada S., Murakami N., Ohtahara S. Changes in blood flow in the middle cerebral artery during absence seizures. Pediatr. Neurol. 4:1988;158-161.
    • (1988) Pediatr. Neurol. , vol.4 , pp. 158-161
    • Sanada, S.1    Murakami, N.2    Ohtahara, S.3
  • 35
    • 0002725086 scopus 로고
    • The radioactive deoxyglucose method. Theory, procedure, and applications for the measurement of local glucose utilization in the central nervous system
    • B.W. Agranoff, Aprison M.H. New York: Plenum
    • Sokoloff L. The radioactive deoxyglucose method. Theory, procedure, and applications for the measurement of local glucose utilization in the central nervous system. Agranoff B.W., Aprison M.H. Advances in Neurochemistry. Vol. 4:1982;1-82 Plenum, New York.
    • (1982) Advances in Neurochemistry , vol.4 , pp. 1-82
    • Sokoloff, L.1
  • 37
    • 0042197390 scopus 로고
    • Cerebral metabolism in absence seizures and related syndromes
    • M.S. Myslobodsky, & A.F. Mirsky. New York: Lang
    • Theodore W.H. Cerebral metabolism in absence seizures and related syndromes. Myslobodsky M.S., Mirsky A.F. Elements of Petit Mal Epilepsy. 1988;131-157 Lang, New York.
    • (1988) Elements of Petit Mal Epilepsy , pp. 131-157
    • Theodore, W.H.1
  • 39
    • 0028219920 scopus 로고
    • Correlation of local changes in cerebral blood flow, capillary density, and cytochrome oxidase during development
    • Tuor U.I., Kurpita G., Simone C. Correlation of local changes in cerebral blood flow, capillary density, and cytochrome oxidase during development. J. Comp. Neurol. 342:1994;439-448.
    • (1994) J. Comp. Neurol. , vol.342 , pp. 439-448
    • Tuor, U.I.1    Kurpita, G.2    Simone, C.3
  • 40
    • 0032881072 scopus 로고    scopus 로고
    • Effects of a restricted unilateral neocortical lesion upon cerebral glucose and oxidative metabolisms in fetal and neonatal cats
    • Villablanca J.R., Schmanke T.D., Hovda D.A. Effects of a restricted unilateral neocortical lesion upon cerebral glucose and oxidative metabolisms in fetal and neonatal cats. Dev. Brain Res. 117:1999;1-13.
    • (1999) Dev. Brain Res. , vol.117 , pp. 1-13
    • Villablanca, J.R.1    Schmanke, T.D.2    Hovda, D.A.3
  • 41
    • 0018358930 scopus 로고
    • Changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry
    • Wong-Riley M.T.T. Changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry. Brain Res. 171:1979;11-28.
    • (1979) Brain Res. , vol.171 , pp. 11-28
    • Wong-Riley, M.T.T.1
  • 42
    • 0024561501 scopus 로고
    • Cytochrome oxidase: An endogenous metabolic marker for neuronal activity
    • Wong-Riley M.T.T. Cytochrome oxidase an endogenous metabolic marker for neuronal activity . Trends Neurosci. 12:1989;94-101.
    • (1989) Trends Neurosci. , vol.12 , pp. 94-101
    • Wong-Riley, M.T.T.1
  • 43
    • 0021165033 scopus 로고
    • Effect of impulse blockade on cytochrome oxidase activity in monkey visual cortex
    • Wong-Riley M., Carroll E.W. Effect of impulse blockade on cytochrome oxidase activity in monkey visual cortex. Nature. 307:1984;262-264.
    • (1984) Nature , vol.307 , pp. 262-264
    • Wong-Riley, M.1    Carroll, E.W.2
  • 44
    • 0001222430 scopus 로고
    • Histochemical changes in cytochrome oxidase of cortical barrels after vibrissae removal in neonatal and adult mice
    • Wong-Riley M.T.T., Welt C. Histochemical changes in cytochrome oxidase of cortical barrels after vibrissae removal in neonatal and adult mice. Proc. Natl. Acad. Sci. USA. 77:1980;2333-2337.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 2333-2337
    • Wong-Riley, M.T.T.1    Welt, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.