Endothelins induce ET B receptor-mediated mechanical hypernociception in rat hindpaw: Roles of cAMP and protein kinase C

European Journal of Pharmacology

Volumn 501, Issue 1-3, 2004, Pages 87-94

  Da Cunha, Joice M ^a   Rae, Giles A ^b   Ferreira, Sérgio H ^a   Cunha, Fernando De Q ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

cAMP; Endothelin; Endothelin ET B receptor; Mechanical hyperalgesia; Protein kinase

Indexed keywords

ATENOLOL; CALPHOSTIN C; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); DEXAMETHASONE; ENDOTHELIN 1; ENDOTHELIN 2; ENDOTHELIN 3; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR ANTAGONIST; INDOMETACIN; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; N ACETYLENDOTHELIN 1 [6-21][11,15 ALANINE]; PHOSPHODIESTERASE INHIBITOR; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; ROLIPRAM; STAUROSPORINE; ENDOTHELIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EVOKED RESPONSE; HINDLIMB; HYPERALGESIA; MALE; MECHANICAL STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; ANIMAL; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; METHODOLOGY; PAIN ASSESSMENT; PHYSIOLOGY; WISTAR RAT;

ANIMALS; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELINS; HINDLIMB; MALE; PAIN MEASUREMENT; PROTEIN KINASE C; RATS; RATS, WISTAR; RECEPTOR, ENDOTHELIN B;

EID: 4644269262     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.08.004     Document Type: Article

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