Endothelin-1-induced ET(A) receptor-mediated nociception, hyperalgesia and oedema in the mouse hind-paw: Modulation by simultaneous ET(B) receptor activation

British Journal of Pharmacology

Volumn 129, Issue 5, 2000, Pages 961-968

  Piovezan, Anna P ^a   D'Orléans Juste, Pedro ^b   Souza, Glória E P ^c   Rae, Giles A ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b UNIVERSITY OF SHERBROOKE   (Canada)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Capsaicin; Endothelin; Endothelin receptor antagonist; Hyperalgesia; Inflammation; Nociception; Oedema; Pain

Indexed keywords

ATRASENTAN; CAPSAICIN; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN 3; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; SARAFOTOXIN S6C; SUCCINYLENDOTHELIN 1 [8-21][9 GLUTAMIC ACID 11,15 ALANINE];

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG POTENTIATION; HYPERALGESIA; MALE; MOUSE; NOCICEPTION; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL;

EID: 0034107746     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703154     Document Type: Article

References (49)

1. Arai, H., Hori, S., Aramori, I., Ohkubo, H. & Nakanishi, S. (1990). Cloning and expression of a cDNA encoding an endothelin receptor. Nature, 348, 730-732.
2. Bertelli, A., Clerico, A., Chicca, A., Giovannini, L., Gorio, A. & Romano, M.A. (1992). Role of endothelin-1 in carrageenan-induced inflammation. Int. J. Tissue React., 14, 225-230.
3. Brain, S.D., Thomas, G., Crossman, D.C., Fuller, R. & Church, M.K. (1992). Endothelin-1 induces a histamine-dependent flare in vivo, but does not activate human skin mast cells in vitro. Br. J. Clin. Pharmacol., 33, 117-120.
4. Brändli, P., Loffler, B.M., Breu, V., Osterwalder, R., Maire, J.P. & Clozel, M. (1996). Role of endothelin in mediating neurogenic plasma extravasation in rat dura mater. Pain, 64, 315-322.
5. Carstens, E. (1995). Neural mechanisms of hyperalgesia: peripheral or central sensitization? News Physiol. Sci., 10, 260-265.
6. Dahlof, B., Gustafsson, D., Hedner. D., Jern, S. & Hansson, L. (1990). Regional hemodynamic effects of endothelin-1 in rat and man: unexpected adverse reactions. J. Hypert., 8, 811-817.
7. Davar, G., Hans, G., Fareed, M.U., Sinnott, C. & Strichartz, G. (1998). Behavioral signs of acute pain produced by application of endothelin-1 to rat sciatic nerve. Neuroreport, 9, 2279-2283.
8. De-Melo, J.D., Tonussi, C.R., D'Orléans-Juste, P. & Rae, G.A. (1998). Articular nociception induced by endothelin-1, carrageenan and LPS in naive and previously inflamed knee-joints of the rat: inhibition by endothelin receptor antagonists. Pain, 77,261-270.
9. Dymshitz, J.& Vasko, M.R. (1994). Endothelin-1 enhances capsaicin-induced peptide release and cGMP accumulation in cultures of rat sensory neurons. Neurosci. Lett., 167, 128-132.
10. B receptors in fever induced by LPS (E. coli) in rats. Br. J. Pharmacol., 125, 542-548.
11. Ferreira, S.H., Romitelli, M. & De Nucci, G. (1989). Endothelin-1 participation in overt and inflammatory pain. J. Cardiovasc. Pharmacol., 13 (suppl. 5): S220-S222.
12. A receptor. Eur. J. Pharmacol., 219, 343-344.
13. B receptors. Br. J. Pharmacol., 115, 227-236.
14. A receptors. Br. J. Pharmacol., 109, 880-886.
15. Griswold, D.E., Douglas, S.A., Martin, L.D., Davis, T.G., Davis, L., Ao, Z., Luttmann, M.A., Pullen, M., Nambi, P., Hay, D.W. & Ohlstein, E.H. (1999). Endothelin B receptor modulates inflammatory pain and cutaneous inflammation. Mol. Pharmacol., 56, 807-812.
16. A receptor-selective antagonist, on changes of intraocular pressure, blood-aqueous barrier and aqueous prostaglandin concentrations caused by endothelin-1 in rabbit. Japan. J. Ophthalmol., 40, 26-32.
17. Helset, E., Sildnes, T., Selkelid, R. & Konopski, Z.S. (1993). Endothelin-1 stimulates human monocytes in vitro to release TNF-α, interleukin-β and interleukin-6. Med. Inflamm., 2, 417-422.
18. Hunskaar, S. & Hole, K. (1987). The formalin test in mice: dissociation between inflammatory and non-inflammatory pain. Pain, 30, 103-114.
19. A receptor. Life Sci., 50,247-255.
20. Ishida, K., Takeshige, K. & Minakami, S. (1990). Endothelin-1 enhances Superoxide generation of human neutrophils stimulated by the chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine. Biochem. Biophys. Res. Commun., 173, 496-500.
21. Ishizuka, T., Takamizawa-Matsumoto, M., Suzuki, K. & Kurita, A. (1999). Endothelin-1 enhances vascular cell adhesion molecule-1 expression in tumor necrosis factor alpha-stimulated vascular endothelial cells. Eur. J. Pharmacol., 369, 237-245.
22. 125J]endothelin-1 binding sites in spinal cord and dorsal root ganglia of the rat. Neurosci. Lett., 133,117-120.
23. Klemm, P., Warner, T.D., Hohlfeld, T., Corder, R. & Vane, J.R.(1995). Endothelin-1 mediates ex vivo coronary vasoconstriction caused by exogenous cytokine. Proc. Natl. Acad. Sci. U.S.A., 92, 2691-2695.
24. Kurose, I., Miura, S., Fukumura, D. & Tsuchiya, M. (1993). Mechanisms of endothelin-induced macromolecular leakage in microvascular beds of rat mesentery. Eur. J. Pharmacol., 250, 85-94.
25. Masaki, T., Vane, J.R. & Vanhoutte, P.M. (1994). International Union of Pharmacology nomenclature of endothelin receptors. Pharmacol. Rev., 46, 137-142.
26. McCarron, R.M., Wang, L., Stanimirovic, D.B. & Spatz, M. (1993). Endothelin induction of adhesion molecule expression on human brain microvascular endothelial cells. Neurosci. Lett., 156,31-34.
27. Millan, M.J. (1999). The induction of pain: an integrative review. Prog. Neurobiol., 57, 1-164.
28. A-selective receptor antagonist. J. Pharmacol. Exp. Ther., 276, 473-481.
29. Piovezan, A.P., D'Orléans-Juste, P., Tonussi, C.R. & Rae, G.A. (1997). Endothelins potentiate formalin-induced nociception and paw edema in mice. Can. J. Physiol. Pharmacol., 75, 596-600.
30. Piovezan, A. P., D'Orléans-Juste, P., Tonussi, C.R. & Rae, G.A. (1998). Effects of endothelin-1 on capsaicin-induced nociception in mice. Eur. J. Pharmacol., 351, 15-22.
31. Rae, G.A. & Henriques, M.G.M.O. (1998). Endothelins in inflammation. In: Said, S., (ed.) Pro-inflammatory and Anti-inflammatory Peptides. Marcel and Dekker Inc.: New York, pp. 163-202.
32. Rae, G.A., Piovezan, A.P., D'Orléans-Juste, P. & Souza, G.E.P. (1999). Endothelin-1 causes nociception, hyperalgesia and edema in the mouse hind-paw: effects of endothelin receptor antagonists. Sixth International Conference on Endothelin, Montreal, O 32.
33. Raffa, R.B. & Jacoby, H.I. (1991). Endothelin-1, -2 and -3 directly and big-endothelin-1 indirectly elicit an abdominal constriction response in mice. Life Sci., 48, PL85-PL90.
34. B receptors. J. Pharmacol. Exp. Ther., 276, 647-651.
35. Sakurada, T., Katsumata, K., Tan-No, K., Sakurada, S. & Kisara, K. (1992). The capsaicin test in mice for evaluating tachykinin antagonists in the spinal cord. Neuropharmacology, 31,1279-1285.
36. Sakurai, T., Yanagisawa, M., Takuwa, Y., Miyazaki, H., Kimura, S., Goto, K. & Masaki, T. (1990). Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature, 348, 732-735.
37. A receptor antagonists inhibit allergic inflammation in the mouse. J. Cardiovasc. Pharmacol., 26 (suppl. 3):S416-S418.
38. Stankova, J., D'Orléans-Juste, P. & Rola-Pleszczynki, M. (1996). ET-1 induces interleukin-6 gene expression in human umbilical vein endothelial cells: synergistic effect of interleukin-1. Am. J. Physiol., 271, C1073-C1078.
39. Sugiura, M., Inagami, T. & Kon, V. (1989). Endotoxin stimulated endothelin-release in vivo and in vitro as determined by radio-immunoassay. Biochem. Biophys. Res. Commun., 161, 1220-1227.
40. Vemulapalli, S., Chiu, P.J., Griscti, K., Brown, A., Kurowski, S. & Sybertz, E.J. (1994). Phosphoramidon does not inhibit endogenous endothelin-1 release stimulated by hemorrhage, cytokines and hypoxia in rats. Eur. J. Pharmacol., 257, 95-102.
41. Webb, D.J. (1998). Endothelin: from molecule to man. Br. J. Clin. Pharmacol., 44,9-20.
42. Webb, M.L. & Meek, T.D.( 1997). Inhibitors of endothelin. Med. Res. Rev., 17, 17-67.
43. Wenzel, R.R., Zbinden, S., Noll, G., Meier, B. & Luscher, T.F. (1998). Endothelin-1 induces vasodilation in human skin by nociceptor fibres and release of nitric oxide. Br. J. Clin. Pharmacol., 45, 441-446.
44. Woods, M., Mitchell, J.A., Wood, E.G., Barker, S., Walcot, N.R., Rees, G.M. & Warner, T.D. (1999). Endothelin-1 is induced by cytokines in human vascular smooth muscle cells: evidence for intracellular endothelin-converting enzyme. Mol. Pharmacol., 55,902-909.
45. Wu-Wong, JR., Chiou, W.J., Magnuson, S.R. & Opgenorth, T.J. (1994). Endothelin receptor agonists and antagonists exhibit different dissociation characteristics. Biochim. Biophys. Acta, 1224, 288-294.
46. Yamamura, H., Nabe, T., Kohno, S. & Ohata, K. (1994). Endothelin-1, one of the most potent histamine releasers in mouse peritoneal mast cells. Eur. J. Pharmacol., 265, 9-15.
47. Yoshizawa, T., Kimura, S., Kanazawa, I., Uchiyama, Y., Yanagisawa, M. & Masaki, T. (1989). Endothelin localizes in the dorsal horn and acts on the spinal cord neurones: possible involvement of dihydropyridine-sensitive calcium channels and substance P release. Neurosci. Lett., 102, 179-184.
48. Zimmermann, M. (1983). Ethical guidelines for investigations of experimental pain in conscious animals. Pain, 16, 109-110.
49. A receptors and platelet-activating factor. Br. J. Pharmacol., 127,969-979.