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Volumn 29, Issue 10, 2004, Pages 1807-1816

Protective effect of 1-methylated β-carbolines against 3-morpholinosydnonimine-induced mitochondrial damage and cell viability loss in PC12 cells

Author keywords

1 methylated carbolines; Cell death; differentiated PC12 cells; mitochondrial membrane permeability; reactive nitrogen species

Indexed keywords

2 (4 CARBOXYPHENYL) 4,4,5,5 TETRAMETHYLIMIDAZOLINE 1 OXYL 3 OXIDE; ACETYLCYSTEINE; ANTIOXIDANT; BENZYLOXYCARBONYLASPARTYLGLUTAMYLMETHIONYLASPARTIC ACID; BENZYLOXYCARBONYLLEUCYLGLUTAMINYLHISTIDYLASPARTIC ACID; CARBOLINE DERIVATIVE; CARBONYL DERIVATIVE; CASPASE 3; CASPASE 9; CASPASE INHIBITOR; CYTOCHROME C; DITHIOTHREITOL; GLUTATHIONE; HARMALINE; HARMALOL; HARMINE; LINSIDOMINE; MELATONIN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; URIC ACID;

EID: 4644233834     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NERE.0000042206.46554.e4     Document Type: Article
Times cited : (8)

References (41)
  • 1
    • 0037378026 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease
    • Jenner, P. 2003. Oxidative stress in Parkinson's disease. Ann. Neurol. 53 (suppl 3):S26-S38.
    • (2003) Ann. Neurol. , vol.53 , Issue.3 SUPPL.
    • Jenner, P.1
  • 2
    • 0030592172 scopus 로고    scopus 로고
    • The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death
    • Bernardi, P. 1996. The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death. Biochim. Biophys. Acta 1275:5-9.
    • (1996) Biochim. Biophys. Acta , vol.1275 , pp. 5-9
    • Bernardi, P.1
  • 6
    • 0029844003 scopus 로고    scopus 로고
    • Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons
    • Hantraye, P., Brouillet, E., Ferrante, R., Palfi, S., Dolan, R., Matthews, R. T., and Beal, M. F. 1996. Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons. Nat. Med. 2:1017-1021.
    • (1996) Nat. Med. , vol.2 , pp. 1017-1021
    • Hantraye, P.1    Brouillet, E.2    Ferrante, R.3    Palfi, S.4    Dolan, R.5    Matthews, R.T.6    Beal, M.F.7
  • 7
    • 0032947296 scopus 로고    scopus 로고
    • Nitric oxide and mitochondrial respiration
    • Brown, G. C. 1999. Nitric oxide and mitochondrial respiration. Biochim. Biophys. Acta 1411:351-369.
    • (1999) Biochim. Biophys. Acta , vol.1411 , pp. 351-369
    • Brown, G.C.1
  • 8
    • 0029986691 scopus 로고    scopus 로고
    • Nitric oxide inhibits electron transfer and increases superoxide radical production in rat heart mitochondrial and submitochondrial particles
    • Poderoso, J. J., Carreras, M. C., Lisdero, C., Riobo, N., Schopfer, F., and Boveris, A. 1996. Nitric oxide inhibits electron transfer and increases superoxide radical production in rat heart mitochondrial and submitochondrial particles. Arch. Biochem. Biophys. 328:85-92.
    • (1996) Arch. Biochem. Biophys. , vol.328 , pp. 85-92
    • Poderoso, J.J.1    Carreras, M.C.2    Lisdero, C.3    Riobo, N.4    Schopfer, F.5    Boveris, A.6
  • 9
    • 0033615544 scopus 로고    scopus 로고
    • Mitochondrial nitric-oxide synthase stimulation causes cytochrome c release from isolated mitochondria. Evidence for intramitochondrial peroxynitrite formation
    • Ghafourifar, P., Schenk, U., Klein, S. D., and Richter, C. 1999. Mitochondrial nitric-oxide synthase stimulation causes cytochrome c release from isolated mitochondria. Evidence for intramitochondrial peroxynitrite formation. J. Biol. Chem. 274:31185-31188.
    • (1999) J. Biol. Chem. , vol.274 , pp. 31185-31188
    • Ghafourifar, P.1    Schenk, U.2    Klein, S.D.3    Richter, C.4
  • 10
    • 0025688141 scopus 로고
    • Mitochondrial respiratory inhibition by N-methylated β-carboline derivatives structurally resembling N-methyl-4-phenylpyridine
    • Albores, R., Neafsey, E. J., Drucker, G., Fields, J. Z., and Collins, M. A. 1990. Mitochondrial respiratory inhibition by N-methylated β-carboline derivatives structurally resembling N-methyl-4-phenylpyridine. Proc. Natl. Acad. Sci. USA 87:9368-9372.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9368-9372
    • Albores, R.1    Neafsey, E.J.2    Drucker, G.3    Fields, J.Z.4    Collins, M.A.5
  • 11
    • 0030462474 scopus 로고    scopus 로고
    • Elevated levels of harman and norharman in cerebrospinal fluid of parkinsonian patients
    • Kuhn, W., Müller, T., Grosse, H., and Rommelspacher, H. 1996. Elevated levels of harman and norharman in cerebrospinal fluid of parkinsonian patients. J. Neural. Transm. 103:1435-1440.
    • (1996) J. Neural. Transm. , vol.103 , pp. 1435-1440
    • Kuhn, W.1    Müller, T.2    Grosse, H.3    Rommelspacher, H.4
  • 14
    • 0028176878 scopus 로고
    • + in PC12 cells: Insights into potential neurotoxicants in Parkinson's disease
    • + in PC12 cells: insights into potential neurotoxicants in Parkinson's disease. J. Neurochem. 62:1503-1510.
    • (1994) J. Neurochem. , vol.62 , pp. 1503-1510
    • Cobuzzi Jr., R.J.1    Neafsey, E.J.2    Collins, M.A.3
  • 15
    • 0027171217 scopus 로고
    • Degeneration of Purkinje cells in parasagittal zones of the cerebellar vermis after treatment with ibogaine or harmaline
    • O'Hearn, E. and Molliver, M. E. 1993. Degeneration of Purkinje cells in parasagittal zones of the cerebellar vermis after treatment with ibogaine or harmaline. Neuroscience 55:303-310.
    • (1993) Neuroscience , vol.55 , pp. 303-310
    • O'Hearn, E.1    Molliver, M.E.2
  • 16
    • 0025912665 scopus 로고
    • Antioxidative properties of harman and β-carboline alkaloids
    • Tse, S. Y. H., Mak, I. T., and Dickens, B. F. 1991. Antioxidative properties of harman and β-carboline alkaloids. Biochem. Pharmacol. 42:459-464.
    • (1991) Biochem. Pharmacol. , vol.42 , pp. 459-464
    • Tse, S.Y.H.1    Mak, I.T.2    Dickens, B.F.3
  • 17
    • 0022580998 scopus 로고
    • MD240928 and harmaline: Opposite selectivity in antagonism of the inactivation of types a and B monoamine oxidase by pargyline in mice
    • Fuller, R., Wong, C. J., and Hemrick-Luecke, S. K. 1986. MD240928 and harmaline: opposite selectivity in antagonism of the inactivation of types A and B monoamine oxidase by pargyline in mice. Life Sci. 38:409-412.
    • (1986) Life Sci. , vol.38 , pp. 409-412
    • Fuller, R.1    Wong, C.J.2    Hemrick-Luecke, S.K.3
  • 18
    • 0343081001 scopus 로고    scopus 로고
    • Protective effect of harmalol and harmaline on MPTP neurotoxicity in the mouse and dopamine-induced damage of brain mitochondria and PC12 Cells
    • Lee, C. S., Han, E. S., Jang, Y. Y., Han, J. H., Ha, H. W., and Kim, D. E. 2000. Protective effect of harmalol and harmaline on MPTP neurotoxicity in the mouse and dopamine-induced damage of brain mitochondria and PC12 Cells. J. Neurochem. 75:521-531.
    • (2000) J. Neurochem. , vol.75 , pp. 521-531
    • Lee, C.S.1    Han, E.S.2    Jang, Y.Y.3    Han, J.H.4    Ha, H.W.5    Kim, D.E.6
  • 19
    • 0029844831 scopus 로고    scopus 로고
    • The role of monoamine metabolism in oxidative glutamate toxicity
    • Maher, P. and Davis, J. B. 1996. The role of monoamine metabolism in oxidative glutamate toxicity. J. Neurosci. 16:6394-6401.
    • (1996) J. Neurosci. , vol.16 , pp. 6394-6401
    • Maher, P.1    Davis, J.B.2
  • 20
    • 0034969732 scopus 로고    scopus 로고
    • Protective effect of harmaline and harmalol against dopamine- And 6-hydroxydopamine-induced oxidative damage of brain mitochondria and synaptosomes, and viability loss of PC12 cells
    • Kim, D. H., Jang, Y. Y., Han, E. S., and Lee, C. S. 2001. Protective effect of harmaline and harmalol against dopamine- and 6-hydroxydopamine-induced oxidative damage of brain mitochondria and synaptosomes, and viability loss of PC12 cells. Eur. J. Neurosci. 13:1861-1872.
    • (2001) Eur. J. Neurosci. , vol.13 , pp. 1861-1872
    • Kim, D.H.1    Jang, Y.Y.2    Han, E.S.3    Lee, C.S.4
  • 21
    • 0036229947 scopus 로고    scopus 로고
    • Propargylamines induce antiapoptotic new protein synthesis in serum-and nerve growth factor (NGF)-withdrawn, NGF-differentiated PC-12 cells
    • Tatton, W. G., Chalmers-Redman, R. M. E., Ju, W. J. H., Mammen, M., Carlile, G. W., Pong, A. W., and Tatton, N. A. 2002. Propargylamines induce antiapoptotic new protein synthesis in serum-and nerve growth factor (NGF)-withdrawn, NGF-differentiated PC-12 cells. J. Pharmacol. Exp. Ther. 301:753-764.
    • (2002) J. Pharmacol. Exp. Ther. , vol.301 , pp. 753-764
    • Tatton, W.G.1    Chalmers-Redman, R.M.E.2    Ju, W.J.H.3    Mammen, M.4    Carlile, G.W.5    Pong, A.W.6    Tatton, N.A.7
  • 22
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann, T. 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65:55-63.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 24
    • 0033984147 scopus 로고    scopus 로고
    • Role of the mitochondrial membrane permeability transition (MPT) in rotenone-induced apoptosis in liver cells
    • Isenberg, J. S. and Klaunig, J. E. 2000. Role of the mitochondrial membrane permeability transition (MPT) in rotenone-induced apoptosis in liver cells. Toxicol. Sci. 53:340-351.
    • (2000) Toxicol. Sci. , vol.53 , pp. 340-351
    • Isenberg, J.S.1    Klaunig, J.E.2
  • 25
    • 0034022635 scopus 로고    scopus 로고
    • Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occurring during 7-ketocholesterol-induced apoptosis
    • Lizard, G., Miguet, C., Bessede, G., Monier, S., Gueldry, S., Neel, D., and Gambert, P. 2000. Impairment with various antioxidants of the loss of mitochondrial transmembrane potential and of the cytosolic release of cytochrome c occurring during 7-ketocholesterol-induced apoptosis. Free Radic. Biol. Med. 28:743-753.
    • (2000) Free Radic. Biol. Med. , vol.28 , pp. 743-753
    • Lizard, G.1    Miguet, C.2    Bessede, G.3    Monier, S.4    Gueldry, S.5    Neel, D.6    Gambert, P.7
  • 26
    • 0031773366 scopus 로고    scopus 로고
    • Catecholamines potentiate amyloid β-peptide neurotoxicity: Involvement of oxidative stress, mitochondrial dysfunction, and perturbed calcium homeostasis
    • Fu, W., Luo, H., Parthasarathy, S., and Mattson, M. P. 1998. Catecholamines potentiate amyloid β-peptide neurotoxicity: involvement of oxidative stress, mitochondrial dysfunction, and perturbed calcium homeostasis. Neurobiol. Dis. 5:229-243.
    • (1998) Neurobiol. Dis. , vol.5 , pp. 229-243
    • Fu, W.1    Luo, H.2    Parthasarathy, S.3    Mattson, M.P.4
  • 27
    • 0031013986 scopus 로고    scopus 로고
    • Increase in gamma-glutamyltransferase by glutathione depletion in rat type II pneumocytes
    • van Klaveren, R. J., Hoet, P. H., Pype, J. L., Demedts, M., and Nemery, B. 1997. Increase in gamma-glutamyltransferase by glutathione depletion in rat type II pneumocytes. Free Radic. Biol. Med. 22:525-534.
    • (1997) Free Radic. Biol. Med. , vol.22 , pp. 525-534
    • Van Klaveren, R.J.1    Hoet, P.H.2    Pype, J.L.3    Demedts, M.4    Nemery, B.5
  • 28
    • 0031019484 scopus 로고    scopus 로고
    • Peroxynitrite-dependent aromatic hydroxylation and nitration of salicylate and phenylalanine. Is hydroxyl radical involved?
    • Kaur, H., Whiteman, M., and Halliwell, B. 1997. Peroxynitrite-dependent aromatic hydroxylation and nitration of salicylate and phenylalanine. Is hydroxyl radical involved? Free Radic. Res. 26:71-82.
    • (1997) Free Radic. Res. , vol.26 , pp. 71-82
    • Kaur, H.1    Whiteman, M.2    Halliwell, B.3
  • 30
    • 0020422695 scopus 로고
    • Superoxide dependent formation of hydroxyl radicals and lipid peroxidation in the presence of iron salts. Detection of 'catalytic' iron and anti-oxidant activity in extracellular fluids
    • Gutteridge, J. M. C., Rowley, D. A., and Halliwell, B. 1982. Superoxide dependent formation of hydroxyl radicals and lipid peroxidation in the presence of iron salts. Detection of 'catalytic' iron and anti-oxidant activity in extracellular fluids. Biochem. J. 201:605-609.
    • (1982) Biochem. J. , vol.201 , pp. 605-609
    • Gutteridge, J.M.C.1    Rowley, D.A.2    Halliwell, B.3
  • 32
    • 0030775042 scopus 로고    scopus 로고
    • Decreased glutathione results in calcium-mediated cell death in PC12
    • Jurma, O. P., Horn, D. G., and Andersen, J. K. 1997. Decreased glutathione results in calcium-mediated cell death in PC12. Free Radic. Biol. Med. 23:1055-1066.
    • (1997) Free Radic. Biol. Med. , vol.23 , pp. 1055-1066
    • Jurma, O.P.1    Horn, D.G.2    Andersen, J.K.3
  • 34
    • 0033805296 scopus 로고    scopus 로고
    • Triggering and modulation of apoptosis by oxidative stress
    • Chandra, J., Samali, A., and Orrenius, S. 2000. Triggering and modulation of apoptosis by oxidative stress. Free Radic. Biol. Med. 29:323-333.
    • (2000) Free Radic. Biol. Med. , vol.29 , pp. 323-333
    • Chandra, J.1    Samali, A.2    Orrenius, S.3
  • 35
    • 0033822197 scopus 로고    scopus 로고
    • Nitric-oxide-induced necrosis and apoptosis in PC12 cells mediated by mitochondria
    • Bal-Price, A. and Brown, G. C. 2000. Nitric-oxide-induced necrosis and apoptosis in PC12 cells mediated by mitochondria. J. Neurochem. 75:1455-1464.
    • (2000) J. Neurochem. , vol.75 , pp. 1455-1464
    • Bal-Price, A.1    Brown, G.C.2
  • 36
    • 0037303479 scopus 로고    scopus 로고
    • Nitric oxide-induced mitochondrial dysfunction: Implications for neurodegeneration
    • Stewart, V. C. and Heales, S. J. R. 2003. Nitric oxide-induced mitochondrial dysfunction: implications for neurodegeneration. Free Radic. Biol. Med. 34:287-303.
    • (2003) Free Radic. Biol. Med. , vol.34 , pp. 287-303
    • Stewart, V.C.1    Heales, S.J.R.2
  • 38
    • 0031952527 scopus 로고    scopus 로고
    • Endogenously occurring β-carboline induces parkinsonism in nonprimate animals: A possible causative protoxin in idiopathic Parkinson's disease
    • Matsubara, K., Gonda, T., Sawada, H., Uezono, T., Kobayashi, Y., Kawamura, T., Ohtaki, K., Kimura, K., and Akaike, A. 1998. Endogenously occurring β-carboline induces parkinsonism in nonprimate animals: a possible causative protoxin in idiopathic Parkinson's disease. J. Neurochem. 70:727-735.
    • (1998) J. Neurochem. , vol.70 , pp. 727-735
    • Matsubara, K.1    Gonda, T.2    Sawada, H.3    Uezono, T.4    Kobayashi, Y.5    Kawamura, T.6    Ohtaki, K.7    Kimura, K.8    Akaike, A.9
  • 39
    • 0022365018 scopus 로고
    • Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease: A longterm study
    • Birkmayer, W., Knoll, J., Riederer, P., Youdim, M. B., Hars, V., and Marton, J. 1985. Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease: a longterm study. J. Neural. Transm. 64:113-127.
    • (1985) J. Neural. Transm. , vol.64 , pp. 113-127
    • Birkmayer, W.1    Knoll, J.2    Riederer, P.3    Youdim, M.B.4    Hars, V.5    Marton, J.6
  • 40
    • 0029731378 scopus 로고    scopus 로고
    • Modulation of gene expression rather than monoamine oxidase inhibition: (-)-deprenyl-related compounds in controlling neurodegeneration
    • Tatton, W. G. and Chalmers-Redman, R. M. 1996. Modulation of gene expression rather than monoamine oxidase inhibition: (-)-deprenyl-related compounds in controlling neurodegeneration. Neurology 47:8171-5183.
    • (1996) Neurology , vol.47 , pp. 8171-15183
    • Tatton, W.G.1    Chalmers-Redman, R.M.2
  • 41
    • 0033042075 scopus 로고    scopus 로고
    • Dopamine and glutamate neurotoxicity in cultured chick telencephali cells: Effects of NMDA antagonists, antioxidants and MAO inhibitors
    • Jacobsson, S. O. and Fowler, C. J. 1999. Dopamine and glutamate neurotoxicity in cultured chick telencephali cells: effects of NMDA antagonists, antioxidants and MAO inhibitors. Neurochem. Int. 34:49-62.
    • (1999) Neurochem. Int. , vol.34 , pp. 49-62
    • Jacobsson, S.O.1    Fowler, C.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.