Effect of latanoprost on intraocular pressure in mice lacking the prostaglandin FP receptor

Investigative Ophthalmology and Visual Science

Volumn 45, Issue 10, 2004, Pages 3555-3559

  Crowston, Jonathan G ^a   Lindsey, James D ^a   Aihara, Makoto ^b   Weinreb, Robert N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LATANOPROST; PROSTAGLANDIN FP RECEPTOR; PROSTAGLANDIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; INTRAOCULAR PRESSURE; KNOCKOUT MOUSE; MOLECULAR MECHANICS; MOUSE; MOUSE STRAIN; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIHYPERTENSIVE AGENTS; FEMALE; GENOTYPE; INTRAOCULAR PRESSURE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; POLYMERASE CHAIN REACTION; PROSTAGLANDINS F, SYNTHETIC; RECEPTORS, PROSTAGLANDIN;

EID: 4644221068     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.04-0338     Document Type: Article

References (26)

1. 2α in the human eye. Graefes Arch Clin Exp Ophthalmol. 1985;222:139-141.
2. 2α on trabecular outflow facility in cynomolgus monkeys. Exp Eye Res. 1990; 51:87-91.
3. 2α. Curr Eye Res. 1981;1:205-209.
4. Aihara M, Lindsey JD, Weinreb RN. Reduction of intraocular pressure in mouse eyes treated with latanoprost. Invest Ophthalmol Vis Sci. 2002;43:146-150.
5. Benozzi J, Nahum LP, Campanelli JL, Rosenstein RE. Effect of hyaluronic acid on intraocular pressure in rats. Invest Ophthalmol Vis Sci. 2002;43:2196-2200.
6. Weinreb RN, Toris CB, Gabelt BT, Lindsey JD, Kaufman PL. Effects of prostaglandins on the aqueous humor outflow pathways. Surv Ophthalmol. 2002;47(suppl 1):S53-S64.
7. Alm A. Prostaglandin derivates as ocular hypertensive agents. Prog Retin Eye Res. 1998;17:291-312.
8. 2α receptor messenger RNA and protein in the cynomolgus monkey eye. Invest Ophthalmol Vis Sci. 1996; 37:716-726.
9. Anthony TL, Lindsey JD, Aihara M, Weinreb RN. Detection of prostaglandin EP(1), EP(2), and FP receptor subtypes in human sclera. Invest Ophthalmol Vis Sci. 2001;42:3182-3186.
10. 2α receptors in the human trabecular meshwork. Invest Ophthalmol Vis Sci. 1998;39:315-321.
11. Resul B, Stjernschantz J, Selen G, Bito L. Structure-activity relationships and receptor profiles of some ocular hypotensive prostanoids. Surv Ophthalmol. 1997;41(suppl 2):S47-S52.
12. 2α derivatives with prostanoid FP-receptor agonistic activity as potent ocular-hypotensive agents. Biol Pharm Bull. 2003;26:1691-1695.
13. Stjernschantz J, Selen G, Sjoquist B, Resul B. Preclinical pharmacology of latanoprost, a phenyl-substituted PGF2 alpha analogue. Adv Prostaglandin Thromboxane Leukot Res. 1995;23:513-518.
14. Chen J, Woodward DF. Prostanoid-induced relaxation of precontracted cat ciliary muscle is mediated by EP2 and DP receptors. Invest Ophthalmol Vis Sci. 1992;33:3195-3201.
15. 2α effects on intraocular pressure negatively correlate with FP-receptor stimulation. Invest Ophthalmol Vis Sci. 1989;30:1838-1842.
16. Aihara M, Lindsey JD, Weinreb RN. Aqueous humor dynamics in mice. Invest Ophthalmol Vis Sci. 2003;44:5168-5173.
17. Sugimoto Y, Yamasaki A, Segi E, et al. Failure of parturition in mice lacking the prostaglandin F receptor. Science. 1997;277:681-683.
18. Aihara M, Lindsey JD, Weinreb RN. Twenty-four-hour pattern of mouse intraocular pressure. Exp Eye Res. 2003;77:681-686.
19. 2α and latanoprost on phosphoinositide turnover, myosin light chain phosphorylation and contraction in cat iris sphincter. J Ocul Pharmacol Ther. 2003;19:217-231.
20. 2α, latanoprost and carbachol on phosphoinositide turnover, MAP kinases, myosin light chain phosphorylation and contraction and functional existence and expression of FP receptors in bovine iris sphincter. Exp Eye Res. 2004;78:285-296.
21. 2 and arachidonic acid release in cat iris sphincter smooth muscle cells. Exp Eye Res. 2001;72:581-590.
22. 2α treatment reduces collagen types I, III, and IV in the monkey uveoscleral outflow pathway. Arch Ophthalmol. 1999;117:794-801.
23. Lindsey JD, Kashiwagi K, Boyle D, Kashiwagi F, Firestein GS, Weinreb RN. Prostaglandins increase proMMP-1 and proMMP-3 secretion by human ciliary smooth muscle cells. Curr Eye Res. 1996;15:869-875.
24. Weinreb RN, Kashiwagi K, Kashiwagi F, Tsukahara S, Lindsey JD. Prostaglandins increase matrix metalloproteinase release from human ciliary smooth muscle cells. Invest Ophthalmol Vis Sci. 1997; 38:2772-2780.
25. Weinreb RN, Lindsey JD. Metalloproteinase gene transcription in human ciliary muscle cells with latanoprost. Invest Ophthalmol Vis Sci. 2002;43:716-722.
26. Ocklind A. Effect of latanoprost on the extracellular matrix of the ciliary muscle: a study on cultured cells and tissue sections. Exp Eye Res. 1998;67:179-191.