Localization of the prostaglandin F2α receptor messenger RNA and protein in the cynomolgus monkey eye

Investigative Ophthalmology and Visual Science

Volumn 37, Issue 5, 1996, Pages 716-726

  Ocklind, Anette ^a,d   Lake, Staffan ^b   Wentzel, Parri ^a   Nistér, Monica ^c   Stjernschantz, Johan ^a  

^a Glaucoma Research Laboratories   (Sweden)

^b Preclinical R and D   (Sweden)

^c UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^d PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; POLYCLONAL ANTIBODY; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN RECEPTOR; RECEPTOR PROTEIN; PRIMER DNA; PROSTAGLANDIN F2ALPHA RECEPTOR; RNA DIRECTED DNA POLYMERASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; EYE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MONKEY; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE DISTRIBUTION; AMINO ACID SEQUENCE; ANIMAL; CELL CULTURE; CHEMISTRY; CYTOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN; MACACA; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PIGMENT EPITHELIUM; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELLS, CULTURED; DINOPROST; DNA PRIMERS; EYE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MACACA FASCICULARIS; MOLECULAR SEQUENCE DATA; PIGMENT EPITHELIUM OF EYE; POLYMERASE CHAIN REACTION; RECEPTORS, PROSTAGLANDIN; RNA, MESSENGER; RNA-DIRECTED DNA POLYMERASE; SEQUENCE HOMOLOGY, AMINO ACID; TISSUE DISTRIBUTION;

EID: 0029664448     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Abdel-Latif AA Regulation of arachidonate release, prostaglandin synthesis, and sphincter constriction in the mammalian iris-ciliary body. In: Bito LZ, Stjernschantz J, eds. The Ocular Effects of Prostaglandins and Other Eicosanoids. New York: Alan Liss; 1989:53-72.
2. Weinreb RN, Polansky JR, Alvarado JA, Mitchell MD. Arachidonic acid metabolism in human trabecular meshwork cells. Invest Ophthalmol Vis Sci. 1988;29:1708-1712.
3. Van Alpen GWHM, Wilhelm PB, Elsenfeld PW. The effect of prostaglandins on the isolated internal muscles of the mammalian eye, including man. Doc Ophthalmol. 1977;42:397-315.
4. 2α in the human eye. Graefe's Arch Clin Exp Ophthalmol. 1985;222:139-141.
5. 2α. Curr Eye Res. 1981;1:205-209.
6. 2α on aqueous humor dynamics in cynomolgus monkeys. Curr Eye Res. 1987;6:1035-1044.
7. 2α-isopropyl ester in the cynomolgus monkey. Exp Eye Res. 1989;48:707-716.
8. 2α analogue on aqueous humor dynamics in human eyes. Exp Eye Res. 1992;5(suppl):43. Abstract.
9. Kennedy I, Coleman RA, Humphrey PPA, Levy GP, Lumley P. Studies on the characterization of prostanoid receptors: A proposed classification. Prostaglandins. 1982;24:667-689.
10. Coleman RA, Humphrey PPA, Kennedy I. Prostanoid receptors in smooth muscle: Further evidence for a proposed working classification. Trends Autonomic Pharmacol. 1982;3:35-49.
11. 2α receptor. J Biol Chem. 1994;269:1356-1360.
12. 2α receptor. J Biol Chem. 1994;269:3881-3886.
13. Abramowich M, Boie Y, Ngyen T, et al. Cloning and expression of a cDNA for the human prostanoid FP receptor. J Biol Chem. 1994;269:2632-2636.
14. 2α receptor. FEBS Lett. 1994;355:317-325.
15. Thierauch KH, Dinter H, Stock G. Prostaglandins and their receptors: II: Receptor structure and signal transduction. J Hypertens. 1994;12:1-5.
16. Wiedemann P, Ryan SJ, Novak P, Sorgente N. Vitreous stimulates proliferation of fibroblasts and retinal pigment epithelial cells. Exp Eye Res. 1985;41:619-629.
17. Hunt RC, Davis AA. Altered expression of keratin and vimentin in human retinal pigment epithelial cells in vivo and in vitro. J Cell Physiol 1990;145:187-199.
18. 2α on calcium efflux. Invest Ophthalmol Vis Sci. 1992;33:2679-2686.
19. Chamley-Campbell J, Campbell GR, Ross R. The smooth muscle in cell culture. Physiol Rev. 1979;59:1-67.
20. Devereux A. A comprehensive set of sequence analysis programs for the VAX. Nucl Acids Res. 1984;12:387-395.
21. Ocklind A, Lake S, Krook K, Hallin I, Nistér M, Westermark B. Localization of the prostaglandin F2 alpha receptor in rat tissues. Prostaglandins Leukot Essent Fatty Acids. 1996;in press.
22. 2α. Physiol Rev. 1976;56:595-651.
23. 2α-binding sites on rat hepatocyte plasma membranes. Eur J Biochem. 1993;211:163-169.
24. 2α receptors coupled to phospholipase C. Biochem Biophys Res Comm. 1991;178:946-952.
25. 2α receptor is the predominant prostanoid receptor in the human ciliary muscle. Br J Ophthalmol. 1993;77:110-114.
26. de Waele M, Renmans W, Segers E, de Valck V, Jochmans K, Van Camp B. An immunogold-silver staining method for detection of cell surface antigens in cell smears. J Histochem Cytochem. 1989;37:1855-1862.
27. Abramowitz M, Adam M, Bogie Y, et al. Human prostanoid receptors: Cloning and characterization. In: Samuelsson B, Ramwell PW, et al, eds. Advances in Prostaglandin and Thromboxane Research. 1995;23:499-505.