TRE-dependent transcription activation by JDP2-CHOP10 association

Nucleic Acids Research

Volumn 36, Issue 11, 2008, Pages 3608-3619

  Weidenfeld baranboim, Keren ^a   Bitton worms, Keren ^a   Aronheim, Ami ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

C JUN DIMERIZATION PROTEIN 2; CCAAT ENHANCER BINDING PROTEIN; DNA; LEUCINE ZIPPER PROTEIN; PROTEIN CHOP10; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRAIN 3T3; CELL VIABILITY; COMPLEX FORMATION; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; DNA BINDING; DNA RESPONSIVE ELEMENT; ENDOPLASMIC RETICULUM STRESS; GENE OVEREXPRESSION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; TRANSCRIPTION INITIATION;

ANIMALS; DNA; ENDOPLASMIC RETICULUM; HELA CELLS; HUMANS; IMMUNOPRECIPITATION; MICE; NIH 3T3 CELLS; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS P21(RAS); RATS; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; RESPONSE ELEMENTS; TETRADECANOYLPHORBOL ACETATE; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR CHOP; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 46349099090     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkn268     Document Type: Article

References (41)

1. Vinson,C., Myakishev,M., Acharya,A., Mir,A.A., Moll,J.R. and Bonovich,M. (2002) Classification of human B-ZIP proteins based on dimerization properties. Mol. Cell. Biol., 22, 6321-6335.
2. Shaulian,E. and Karin,M. (2002) AP-1 as a regulator of cell life and death. Nat. Cell Biol., 4, E131-E136.
3. Newman,J.R. and Keating,A.E. (2003) Comprehensive identification of human bZIP interactions with coiled-coil arrays. Science, 300 2097-2101.
4. Ubeda,M., Vallejo,M. and Habener,J.F. (1999) CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins. Mol. Cell. Biol., 19, 7589-7599.
5. Aronheim,A., Zandi,E., Hennemann,H., Elledge,S. and Karin,M. (1997) Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions. Mol. Cell. Biol., 17, 3094-3102.
6. Jin,C., Ugai,H., Song,J., Murata,T., Nili,F., Sun,K., Horikoshi,M. and Yokoyama,K.K. (2001) Identification of mouse Jun dimerization protein 2 as a novel repressor of ATF-2. FEBS Lett., 489, 34-41.
7. Broder,Y.C., Katz,S. and Aronheim,A. (1998) The Ras recruitment system a novel approach to the study of protein-protein interactions. Curr. Biol., 8, 1121-1124.
8. Jin,C., Li,H., Murata,T., Sun,K., Horikoshi,M., Chiu,R. and Yokoyama,K.K. (2002) JDP2, a repressor of AP-1, recruits a histone deacetylase 3 complex to inhibit the retinoic acid-induced differentiation of F9 cells. Mol. Cell. Biol., 22, 4815-4926.
9. Jin,C., Kato,K., Chimura,T., Yamasaki,T., Nakade,K., Murata,T., Li,H., Pan,J., Zhao,M., Sun,K. et al. (2006) Regulation of histone acetylation and nucleosome assembly by transcription factor JDP2. Nat. Struct. Mol. Biol., 13, 331-338.
10. Katz,S., Heinrich,R. and Aronheim,A. (2001) The AP-1 repressor, JDP2, is a bona fide substrate for the c-Jun N- terminal kinase. FEBS Lett. 506, 196-200.
11. Katz,S. and Aronheim,A. (2002) Differential targeting of the stress mitogen-activated protein kinases to the c-Jun dimerization protein 2. Biochem. J., 368, 939-945.
12. Ostrovsky,O., Bengal,E. and Aronheim,A. (2002) Induction of terminal differentiation by the c-Jun dimerization protein JDP2 in C2 myoblasts and rhabdomyosarcoma cells. J. Biol. Chem., 277, 40043-40054.
13. Kawaida,R., Ohtsuka,T., Okutsu,J., Takahashi,T., Kadono,Y., Oda,H., Hikita,A., Nakamura,K., Tanaka,S. and Furukawa,H. (2003) Jun dimerization protein 2 (JDP2), a member of the AP-1 family of transcription factor, mediates osteoclast differentiation induced by RANKL. J. Exp. Med., 197, 1029-1035.
14. Nakade,K., Pan,J., Yoshiki,A., Ugai,H., Kimura,M., Liu,B., Li,H., Obata,Y., Iwama,M., Itohara,S. et al. (2007) JDP2 suppresses adipocyte differentiation by regulating histone acetylation. Cell Death Diff., 14, 1398-1405.
15. Hai,T., Wolfgang,C.D., Marsee,D.K., Allen,A.E. and Sivaprasad,U. (1999) ATF3 and stress responses. Gene Express., 7, 321-335.
16. Hai,T. and Curran,T. (1991) Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity. Proc. Natl Acad. Sci. USA, 88, 3720-3724.
17. Chen,B.P.C., Wolfgang,C.D. and Hai,T. (1996) Analysis of ATF3, a transcription factor induced by physiological stresses and modulated by gadd153/Chop. Mol. Cell. Biol., 16, 1157-1168.
18. Kehat,I., Heinrich,R., Ben-Izhak,O., Miyazaki,H., Gutkind,J.S. and Aronheim,A. (2606) Inhibition of basic leucine zipper transcription is a major mediator of atrial dilatation. Cardiovasc. Res., 70, 543-554.
19. Okamoto,Y., Chaves,A., Chen,J., Kelley,R., Jones,K., Weed,H.G., Gardner,K.L., Gangi,L., Yamaguchi,M., Klomkleaw,W. et al. (2001) Transgenic mice with cardiac-specific expression of activating transcription factor 3, a stress-inducible gene, have conduction abnormalities and contractile dysfunction. Am. J. Pathol., 159 639-650.
20. Kehat,I., Hasin,T. and Aronheim,A. (2006) The role of basic leucine zipper protein-mediated transcription in physiological and pathological myocardial hypertrophy. Ann. NY Acad. Sci., 1080, 97-109.
21. Piu,F., Aronheim,A., Katz,S. and Karin,M. (2001) AP-1 repressor protein JDP-2: Inhibition of UV-mediated apoptosis through p53 down-regulation. Mol. Cell. Biol., 21, 3012-3024.
22. Heinrich,R., Livne,E., Ben-Izhak,O. and Aronheim,A. (2004) The c-Jun dimerization rotein 2 inhibits cell transformation and acts as a tumor suppressor gene. J. Biol. Chem., 279, 5708-5715.
23. Rasmussen,M.H., Sorensen,A.B., Morris,D.W., Dutra,J.C., Engelhard,E.K., Wang,C.L., Schmidt,J. and Pedersen,F.S. (2005) Tumor model-specific proviral insertional mutagenesis of the Fos/Jdp2/Batf locus. Virology 337, 353-364.
24. Hwang,H.C., Martins,C.P., Bronkhorst,Y., Randel,E., Berns,A., Fero,M. and Clurman,B.E. (2002) Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis. Proc. Natl Acad Sci. USA, 99, 11293-11298.
25. Stewart,M., Mackay,N., Hanlon,L., Blyth,K., Scobie,L., Cameron,E. and Neil,J.C. (2007) Insertional mutagenesis reveals Progression genes and checkpoints in MYC/Runx2 lymphomas. Cancer Res., 67, 5126-5133.
26. Ron,D. and Habener,J.F. (1992) CHOP, a novel developmentally regulated nuclear protein that dimerize with transcription factors C/EBP and LAP and functions as a dominant negative inhibitor of gene transcription. Genes Dev., 6, 439-453.
27. Allan,A.L., Albanese,C., Pestell,R.G. and LaMarre,J. (2001) Activating transcription factor 3 induces DNA synthesis and expression of cyclin D1 in hepatocytes. J. Biol. Chem., 276, 27272-27280.
28. Aronheim,A. (2004) Ras signaling pathway for analysis of protein-protein interactions in yeast and mammalian cells. Methods Mol. Biol., 250, 251-262.
29. Zinszner,H., Kuroda,M., Wang,X., Batchvarova,N., Lightfoot,R.T., Remotti,H., Stevens,J.L. and Ron,D. (1998) CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev., 12, 982-995.
30. Schreiber,E., Matthias,P., Muller,M.M. and Schaffner,W. (1989) Rapid detection of octamer binding proteins with 'mini-extracts' prepared from small number of cells. Nucleic Acids Res., 17, 6419.
31. Harding,H.P., Novoa,I., Zhang,Y., Zeng,H., Wek,R., Schapira,M. and Ron,D. (2000) Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol. Cell, 6, 1099-1108.
32. Oyadomari,S. and Mori,M. (2004) Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Diff., 11, 381-389.
33. Bakiri,L., Matsuo,K., Wisniewska,M., Wagner,E.F. and Yaniv,M. (2002) Promoter specificity and biological activity of tethered AP-1 dimers. Mol. Cell. Biol., 22, 4952-4964.
34. Ubeda,M., Wang,X.Z., Zinszner,H., Wu,I., Habener,J.F. and Ron,D. (1996) Stress-induced binding of the transcriptional factor CHOP to a novel DNA control element. Mol. Cell. Biol., 16, 1479-1489.
35. Sok,J., Wang,X.Z., Batchvarova,N., Kuroda,M., Harding,H. and Ron,D. (1999) CHOP-Dependent stress-inducible expression of a novel form of carbonic anhydrase VI. Mol. Cell. Biol., 19, 495-504.
36. Marciniak,S.J., Yun,C.Y., Oyadomari,S., Novoa,I., Zhang,Y., Jungreis,R., Nagata,K., Harding,H.P. and Ron,D. (2004) CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev., 18, 3066-3077.
37. Lerdrup,M., Holmberg,C., Dietrich,N., Shaulian,E., Herdegen,T., Jaattela,M. and Kallunki,T. (2005) Depletion of the AP-1 repressor JDP2 induces cell death similar to apoptosis. Biochim. Biophys. Acta, 1745, 29-37.
38. Jiang,H.Y., Wek,S.A., McGrath,B.C., Lu,D., Hai,T., Harding,H.P., Wang,X., Ron,D., Cavener,D.R. and Wek,R.C. (2004) Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response. Mol. Cell. Biol., 24, 1365-1377.
39. Wang,X.Z. and Ron,D. (1996) Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase. Science, 272, 1347-1349.
40. Rong,R., Montalbano,J., Jin,W., Zhang,J., Garling,M., Sheikh,M.S. and Huang,Y. (2005) Oncogenic Ras-mediated down-regulation of Gadd153/CHOP is required for Ras-induced cellular transformation. Oncogene, 24, 4867-4872.
41. Marjon,P.L., Bobrovnikova-Marjon,E.V. and Abcouwer,S.F. (2004) Expression of the pro-angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 by human breast carcinomas is responsive to nutrient deprivation and endoplasmic reticulum stress. Mol. Cancer 3, 4.