AM251 suppresses the viability of HepG2 cells through the AMPK (AMP-activated protein kinase)-JNK (c-Jun N-terminal kinase)-ATF3 (activating transcription factor 3) pathway

Biochemical and Biophysical Research Communications

Volumn 370, Issue 4, 2008, Pages 641-645

  Lee, Yun Mi ^a   Uhm, Kyung Ok ^a   Lee, Eun Soo ^a   Kwon, Joseph ^b   Park, Sun Hwa ^a   Kim, Hyeon Soo ^a  

^a Korea University College of Medicine   (South Korea)

^b Korea Basic Science Institute (KBSI)   (South Korea)

Author keywords

AM251; AMPK; ATF3; Cannabinoid antagonist; JNK

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; ACTIVATING TRANSCRIPTION FACTOR 3; ADENYLATE KINASE; STRESS ACTIVATED PROTEIN KINASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; HEPATOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ACTIVATING TRANSCRIPTION FACTOR 3; AMINOIMIDAZOLE CARBOXAMIDE; ANTINEOPLASTIC AGENTS; CANNABINOIDS; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MULTIENZYME COMPLEXES; PHOSPHORYLATION; PIPERIDINES; PROTEIN-SERINE-THREONINE KINASES; PYRAZOLES; RIBONUCLEOTIDES; SIGNAL TRANSDUCTION;

EID: 46349091235     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.04.003     Document Type: Article

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