Cloning and SNP screening of the TLR4 gene and the association between its polymorphism and somatic cell score in dairy cattle

South African Journal of Animal Science

Volumn 38, Issue 2, 2008, Pages 101-109

  Wang, Xing Ping ^a   Xu, Shang Zhong ^b   Gao, Xue ^b   Li, Jun Ya ^b   Ren, Hong Yan ^b   Luoren, Zhuo Ma ^a  

^a XINXIANG MEDICAL UNIVERSITY   (China)

^b INSTITUTE OF PLANT PROTECTION   (China)

Author keywords

Cattle; Mastitis; SCS; SNP; Somatic cell count; TLR4

Indexed keywords

BACTERIA (MICROORGANISMS); BOS; BOVINAE; NEGIBACTERIA;

EID: 46349086977     PISSN: 03751589     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Akira, S., 2003. Toll-like Receptor Signaling. J. Biol. Chem. 278, 38105-38108.
2. Bannerman, D.D., Tupper, J.C., Erwert, R.D., Winn, R.K. & Harlan, J.M., 2002. Divergence of bacterial lipopolysaccharide pro-apoptotic signaling downstream of IRAK-1. J. Biol. Chem. 277, 8048-8053.
3. Brown, C.A., Rischette, S.J. & Schultz, L.H., 1986. Relationship of milking rate to somatic cell count. J. Dairy Sci. 69, 850-854.
4. Chuang, T.H. & Ulevitch, R.J., 2000. Cloning and characterization of a sub-family of human Toll-like receptors: hTLR7, hTLR8 and hTLR9. Eur. Cytokine. Netw. 11, 372-378.
5. Deluyker, H.A., Gay, J.M. & Weaver, L.D., 1993. Interrelationships of somatic cell count, mastitis, and milk yield in a low somatic cell count herd. J. Dairy Sci. 76, 3445-3452.
6. Diamond, G., Kaiser, V., Rhodes, J., Russell, J.P. & Bevins, C. L., 2000. Transcriptional regulation of beta-defencing gene expression in tracheal epithelial cells. Infect. Immun. 68, 113-119.
7. Donald, N.C., David, S.P. & David, A.S., 2004. Toll-like receptors in the pathogenesis of human disease. Nat. Immunol. 10, 975-979.
8. Ghosh, S. & Karin, M., 2002. Missing pieces in the NF-kB puzzle. Cell. 109 (Suppl.), 81-96.
9. Heringstad, B., Gianola, D., Chang, Y.M., Odegard, J. & Klemetsdal, G., 2006. Genetic associations between clinical mastitis and somatic cell score in early first-lactation cows. J. Dairy. Sci. 89, 2236-2244.
10. Klungland, H., Sabry, A., Heringstad, B., Olsen, H.G., Gomez-Raya, L., Vage, D.I., Olsaker, I., Odegard, J., Klemetsdal, G., Schulman, N., Vilkki, J., Ruane, J., Aasland, M., Ronningen, K. & Lien, S., 2001. Quantitative trait loci affecting clinical mastitis and somatic cell count in dairy cattle. Mamm. Genome 12, 837-842.
11. Koivula, M., Mantysaari, E.A., Negussie, E. & Serenius, T., 2005. Genetic and phenotypic relationship among milk yield and somatic cell count before and after clinical mastitis. J. Dairy. Sci. 88, 827-833.
12. McGuire, K., Jones, M., Werling D., Williams, J.L., Glass, E.J. & Jann, O., 2005. Radiation hybrid mapping of all 10 characterized bovine Toll-like receptors. Anim. Genet. 37, 47-50.
13. Rock, F.L., Hardiman,G., Timans, J.C., Kastelein, R.A. & Bazan, J.F., 1998. A family of human receptors structurally related to Drosophila Toll-like receptors. Proc. Natl. Acad. Sci. 95, 588-593.
14. SAS, 1999. Statistical Analysis System user's guide, Ver. 8.2. SAS Institute Inc., Cary, N.C., USA.
15. Sharma, B.S., Leyva, I., Schenkel, F. & Karrow, N.A., 2006. Association of toll-like receptor 4 polymorphisms with somatic cell score and lactation persistency in Holstein bulls. J. Dairy. Sci. 89, 3626-3635.
16. Smirnova, I., Hamblin, M., McBride, C., Beutler, B. & Dirienzo, A., 2001. Excess of rare amino acid polymorphisms in the Toll-like receptor 4 in humans. Genetics 158, 1657-1664.
17. Smirnova, I., Poltorak, A., Chan, E.K., McBride, C. & Beutler, B., 2000. Phylogenetic variation and polymorphism at the toll-like receptor 4 locus (TLR4). Genome Biol. 1, 1-10.
18. Sordillo, L.M. & Streicher, K.L., 2002. Mammary gland immunity and mastitis susceptibility. J. Mamm. Gland Biol. Neoplasia. 55, 135-146.
19. Takeda, K., Kaisho, T. & Akira, S., 2003. Toll-like receptors. Ann. Rev. Immunol. 21, 335-376.
20. Vidal, O., Noguera, J.L., Amills, M., Varona, L., Gil, M., Jimenez, N., Davalos, G., Folch, J.M. & Sanchez, A., 2005. Identification of carcass and meat quality quantitative trait loci in a Landrace pig population selected for growth and leanness. J. Anim. Sci. 83, 293-300.
21. Werling, D. & Jungi, T.W., 2003. Toll-like receptors linking innate and adaptive immune response. Vet. Immunol. Immunopathol. 91, 1-12.
22. White, S.N., Taylor, K.H. Abbey, C.A., Gill, C.A. & Womack, J.E., 2003. Haplotype variation in bovine Toll-like receptor 4 and computational prediction of a positively selected ligand-binding domain. Proc. Natl. Acad. Sci. 100, 10364-10369.