Rates of tympanic membrane closure in double-tympanocentesis studies

Pediatric Infectious Disease Journal

Volumn 27, Issue 6, 2008, Pages 490-493

  Slovik, Youval ^a   Raiz, Simon ^a   Leiberman, Alberto ^a   Puterman, Moshe ^a   Dagan, Ron ^b,c   Leibovitz, Eugene ^b,c  

^a Department of Otolaryngology ^*  (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^c BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Acute otitis media; Healing; Tympanocentesis

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; CEFDINIR; CEFPROZIL; LEVOFLOXACIN;

ACUTE OTITIS MEDIA; ARTICLE; CHILD; EARDRUM; FEMALE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MYRINGOTOMY; PRIORITY JOURNAL; MICROBIOLOGY; OTITIS MEDIA; PARACENTESIS; PHYSIOLOGY; PRESCHOOL CHILD; SECRETORY OTITIS MEDIA; TIME; WOUND HEALING;

CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; MALE; OTITIS MEDIA; OTITIS MEDIA WITH EFFUSION; PARACENTESIS; TIME FACTORS; TYMPANIC MEMBRANE; WOUND HEALING;

EID: 46249110383     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0b013e3181674133     Document Type: Article

References (21)

1. Johnson A, Hawke M. The function of migratory epidermis in the healing of tympanic membrane perforations in guinea-pig. A photographic study. Acta Otolaryngol (Stockh). 1087;103:81-86.
2. Clawson JP, Litton WB. The healing process of tympanic membrane perforations. Trans Am Acad Ophtalmol Otolaryngol. 1971;75:1302-1312.
3. Rahman A, Hultcrantz M, Dirckx J, Margolin G, von Unge M. Fresh tympanic membrane perforations heal without significant loss of strength. Otol Neurotol. 2005;26:1100-1106.
4. 2 laser myringotomy on rat tympanic membranes. Intern J Pediatr Otorhinol. 2004;68:811-815.
5. Spratley J, Hellstrom S, Eriksson PO, Pais-Clemente M. Myringotomy delays the tympanic membrane recovery in acute otitis media: a study in the rat model. Laryngoscope. 2002;112:1474-1481.
6. Hermansson A, Hellstrom S. Healing of tympanic membrane after myringotomy during Streptococcus pneumoniae otitis media. An otomi- croscopic and histologic study in the rat. Ann Otol Rhinol Laryngol. 1996;105:397-404.
7. Dagan R, Hoberman A, Johnson C, et al. Bacteriologic and clinical efficacy of high-dose amoxicillin/clavulanate (90/6.4 mg/kg/day) in children with acute otitis media, including penicillin-resistant Streptococcus pneumoniae. Pediatr Infect Dis . 2001;20:829 -837.
8. Arguedas A, Dagan R, Pichichero M, et al. An open-label, double tympanocentesis study of levofloxacin in the treatment of children with, or at high risk for, recurrent or persistent acute otitis media. Pediatr Infect Dis J. 2006;25:1102-1109.
9. Arguedas A, Dagan R, Leibovitz E, Hoberman A, Pichichero M, Paris M. A multicenter, open-label study of cefdinir in children with acute otitis media at high risk of persistent or recurrent infection. Pediatr Infect Dis J. 2006;25:211-218.
10. Pichichero M, Dagan R, Arguedas A, et al. A multi-center, open-labeled study of cefprozil in children with persistent and recurrent acute otitis media (Abstract G-819). Paper presented at: 45th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy, December 16 -19, 2005; Washington, DC.
11. Dagan R, Abramson O, Leibovitz E, et al. Bacteriologic response to oral cephalosporins: are established susceptibility breakpoints appropriate in the case of acute otitis media? J Infect Dis. 1997;176:1253-1259.
12. Dagan R, Abramson O, Leibovitz E, et al. Impaired bacteriologic response to oral cephalosporins in acute otitis media caused by pneu- mococci with intermediate resistance to penicillin. Pediatr Infect Dis J. 1996;15:980-985.
13. Berger G. Nature of spontaneous tympanic membrane perforation in acute otitis media in children. J Laryngol Otol. 1989;103:1150 -1153.
14. Gladstone HB, Jackler RK, Varav K. Tympanic membrane wound healing. Otolaryngol Clin North Am. 1995;28:913-932.
15. Barzilai A, Dekel B, Passwell JH, Dagan R, Leibovitz E. Cytokine analysis of middle ear effusions during acute otitis media: significant reduction in tumor necrosis factor alpha concentrations correlates with bacterial eradication. Pediatr Infect Dis J. 1999;18:301-303.
16. Barzilai A, Leibovitz E, Laver JH, et al. Dynamics of interleukin-1 production in middle ear fluid during acute otitis media treated with antibiotics. Infection. 1999;27:173-176.
17. Leibovitz E, Dagan R, Abboud MR, et al. Interleukin-8 in middle ear fluid during acute otitis media: correlation with etiology and bacterial eradication. Arch Dis Child. 2000;82:165-168.
18. Barzilai A, Dekel B, Dagan R, Leibovitz E. Middle ear effusion IL-6 in bacterial and non-bacterial acute otitis media. Acta Paediatr Scand. 2000;89:1068-1071.
19. Broides A, Leibovitz E, Dagan R, et al. The cytologic picture of the middle ear fluid during acute otitis media: pneumococcal acute otitis media is associated with highest middle ear fluid white blood cell counts. Pediatr Infect Dis J. 2002;21:57-60.
20. Derlacki EL. Repair of central perforations of tympanic membrane. Arch Otolaryngol. 1953;58:405-420.
21. Griffin WL. A retrospective study of traumatic tympanic membrane perforation in a clinical practice. Laryngoscope. 1979;89:261-282.