Dynamics of interleukin-1 production in middle ear fluid during acute otitis media treated with antibiotics

Infection

Volumn 27, Issue 3, 1999, Pages 173-176

  Barzilai, A ^b   Leibovitz, E ^a   Laver, J H ^a   Piglansky, L ^b   Raiz, S ^b   Abboud, M R ^a   Fliss, D M ^b   Leiberman, A ^b   Dagan, R ^b  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b Soroka University Medical Center ^*

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; ANTIBIOTIC AGENT; AZITHROMYCIN; CEFACLOR; CEFTRIAXONE; INTERLEUKIN 1;

ARTICLE; BACTERIUM CULTURE; BACTERIUM ISOLATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HAEMOPHILUS INFLUENZAE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MORAXELLA CATARRHALIS; MYRINGOTOMY; ORAL DRUG ADMINISTRATION; OTITIS MEDIA; PRESCHOOL CHILD; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES;

ACUTE DISEASE; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; CHILD, PRESCHOOL; EAR, MIDDLE; HUMANS; INFANT; INTERLEUKIN-1; OTITIS MEDIA WITH EFFUSION; PROSPECTIVE STUDIES;

EID: 0033024965     PISSN: 03008126     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02561523     Document Type: Article

References (19)

1. 1. Klein, J. O.: Otitis media. Clin. Infect. Dis. 19 (1994) 823-833.
2. 2. Berman, S.: Otitis media in children. N. Engl. J. Med. 332 (1995) 1560-1565.
3. 3. Baquero, F., Loza, E.: Antibiotic resistance of microorganisms involved in ear, nose and throat infections. Pediatr. Infect. Dis. J. 13 (Suppl.) (1994) S9-S14.
4. 4. Dagan, R., Abramson, O., Leibovitz, E., Lang, R., Goshen, S., Greenberg, D., Yagupsky, P., Leiberman, A., Fliss, D. M.: Impaired bacteriologic response to oral cephalosporins in acute otitis media caused by pneumococci with intermediate resistance to penicillin. Pediatr. Infect. Dis. J. 15 (1996) 980-985.
5. 5. Leibovitz, E., Raiz, S., Piglansky, L., Greenberg, D., Yagupsky, P., Fliss, D. M., Leiberman, A., Dagan, R.: Resistance pattern of middle ear fluid isolates in acute otitis media recently treated with antibiotics. Pediatr. Infect. Dis. J. 17 (1998) 463-469.
6. 6. Bernstein, J. M.: Immunologic reactivity in the middle ear in otitis media with effusion. Otolaryngologic Clinics of North America 24 (1991) 845-859.
7. 7. Saez-Llorens, X.: Pathogenesis of acute otitis media. Pediatr. Infect. Dis. J. 13 (1994) 1035-1038.
8. 8. Fergie, J. E., Purcell, K.: The role of inflammatory mediators and anti-inflammatory drugs in otitis media. Pediatr. Annals 27 (1998) 76-81.
9. 9. Ophir, D., Hahn, T., Schattner, A., Wallach, D., Aviel, A.: Tumor necrosis factor in middle ear effusions. Arch. Otolaryngol. Head Neck Surg. 114 (1988) 1256-1258.
10. 10. Yellon, R. F., Leonard, G., Marucha, P. T., Craven, R., Carpenter, R. J., Lehmann, W. B., Burleson, J. A., Kreutzer, D. L.: Characterization of cytokines present in middle ear effusions. Laryngoscope 101 (1991) 165-169.
11. 11. Juhn, S. K., Tolan, C. T., Garvis, W. J., Cross, D. S., Giebink, G. S.: The levels of 11-1β in human middle ear fluid effusions. Acta Otolaryngol. (Stockh.) (Suppl. 493) (1992) 37-42.
12. 12. Miller, M. D., Krangel, M. S.: Biology and biochemistry of the chemokines: a family of chemotactic and inflammatory cytokines. Crit. Rev. Immunol. 12 (1992) 17-46.
13. 13. Dinarello, C. A.: Role of interleukin-1 in infectious diseases. Immunological Reviews 127 (1992) 119-146.
14. 14. Dinarello, C. A.: Biologic basis for IL-1 in disease. Blood 6 (1996) 2095-2147.
15. 15. Storgaard, M., Larsen, K., Blegvad, S., Nodgaard, H., Ovesen, T., Anderson, P. L., Obel, N.: Interleukin-8 and chemotactic activity of middle ear effusions. J. Infect. Dis. 175 (1997) 474-477.
16. 16. Leibovitz, E., Rouvio, O., Seri, L., Raiz, S., Greenberg, D., Fliss, D. M., Leiberman, A., Rager, B. Dagan, R.: Tumor necrosis factor-α in middle ear fluid during acute otitis media: correlation with etiology and bacterial eradication. 37th Interscience Conference on Antimicrobial Agents and Chemotherapy, 28 September-1 October 1997, Toronto, abstr. K-104.
17. 17. Heikkinen, T., Ghaffar, F., Okorodudu, A. O., Chonmaitree, T.: Serum interleukin-6 in bacterial and nonbacterial acute otitis media. Pediatrics 102 (1998) 296-299.
18. 18. Carlin, S. A., Marchant, C. A., Shurin, P. A., Johnson, C. E., Super, D. M., Rehmus, J. M.: Host factors and early therapeutic response in acute otitis media. J. Pediatr. 118 (1991) 178-183.
19. 19. Dagan, R., Leibovitz, E., Greenberg, D., Yagupsky, P., Fliss, D. M., Leiberman, A.: Early eradication of pathogens from middle ear fluid during antibiotic treatment of acute otitis media is associated with improved clinical outcome. Pediatr. Infect. Dis. J. 17 (1998) 776-782.