The IRBIT domain adds new functions to the AHCY family

BioEssays

Volumn 30, Issue 7, 2008, Pages 642-652

  Devogelaere, Benoit ^a,b   Sammels, Eva ^a   De Smedt, Humbert ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b TIBOTEC BVBA   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSYLHOMOCYSTEINASE; ADENOSYLHOMOCYSTEINASE INHIBITOR; AHCYL1 ENZYME; AHCYL2 ENZYME; IRBIT ENZYME;

CELL DIFFERENTIATION; CELL TYPE; DENDRITIC CELL; ENZYME ACTIVITY; ENZYME METABOLISM; GENE STRUCTURE; HUMAN; MUTATIONAL ANALYSIS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVIEW;

ADENOSYLHOMOCYSTEINASE; AMINO ACID MOTIFS; ANIMALS; EMBRYONIC DEVELOPMENT; HUMANS; LECTINS, C-TYPE; MEMBRANE PROTEINS; PHOSPHORYLATION; PROTEIN PHOSPHATASE 1; TISSUE DISTRIBUTION;

EID: 46049106799     PISSN: 02659247     EISSN: None     Source Type: Journal    
DOI: 10.1002/bies.20772     Document Type: Review

References (82)

1. De La Haba G, Cantoni GL. 1959. The enzymatic synthesis of S-adenosyl-L-homocysteine from adenosine and homocysteine. J Biol Chem 234:603-608.
2. Ueland PM. 1982. Pharmacological and biochemical aspects of S-adenosylhomocysteine and S-adenosylhomocysteine hydrolase. Pharmacol Rev 34:223-253.
3. Hershfield MS, Aiyar VN, Premakumar R, Small WC. 1985. S-Adenosylhomocysteine hydrolase from human placenta. Affinity purification and characterization. Biochem J 230:43-52.
4. Cooper BJ, Key B, Carter A, Angel NZ, Hart DN, et al. 2006. Suppression and overexpression of adenosylhomocysteine hydrolase-like protein-1 (AHCYL1) influences zebrafish embryo development: a possible role for AHCYL1 in inositol phospholipid signaling. J Biol Chem 281:22471-22484.
5. Hasobe M, McKee JG, Borcherding DR, Keller BT, Borchardt RT. 1988. Effects of 9-(trans-2′,trans-3′-dihydroxycyclopent-4′-enyl)- adenine and - 3-deazaadenine on the metabolism of S-adenosylhomocysteine in mouse L929 cells. Mol Pharmacol 33:713-720.
6. Hasobe M, McKee JG, Ishii H, Cools M, Borchardt RT, et al. 1989. Elucidation of the mechanism by which homocysteine potentiates the anti-vaccinia virus effects of the S-adenosylhomocysteine hydrolase inhibitor 9-(trans-2′,trans-3′-dihydroxycyclopent-4′-enyl)-adenine. Mol Pharmacol 36:490-496.
7. Hasobe M, McKee JG, Borchardt RT. 1989. Relationship between intracellular concentration of S-adenosylhomocysteine and inhibition of vaccinia virus replication and inhibition of murine L-929 cell growth. Antimicrob Agents Chemother 33:828-834.
8. Ault-Riche DB, Lee Y, Yuan CS, Hasobe M, Wolfe MS, et al. 1993. Effects of 4′-modified analogs of aristeromycin on the metabolism of S-adenosyl-L-homocysteine in murine L929 cells. Mol Pharmacol 43:989-997.
9. Fontecave M, Atta M, Mulliez E. 2004. S-adenosylmethionine: nothing goes to waste. Trends Biochem Sci 29:243-249.
10. Wolfe MS, Borchardt RT. 1991. S-adenosyl-L-homocysteine hydrolase as a target for antiviral chemotherapy. J Med Chem 34:1521-1530.
11. Liu S, Wolfe MS, Borchardt RT. 1992. Rational approaches to the design of antiviral agents based on S-adenosyl-L-homocysteine hydrolase as a molecular target. Antiviral Res 19:247-265.
12. Bitonti AJ, Baumann RJ, Jarvi ET, McCarthy JR, McCann PP. 1990. Antimalarial activity of a 4′,5′-unsaturated 5′- fluoroadenosine mechanism-based inhibitor of S-adenosyl-L-homocysteine hydrolase. Biochem Pharmacol 40:601-606.
13. Henderson DM, Hanson S, Allen T, Wilson K, Coulter-Karis DE, et al. 1992. Cloning of the gene encoding Leishmania donovani S-adenosylhomocysteine hydrolase, a potential target for antiparasitic chemotherapy. Mol Biochem Parasitol 53:169-183.
14. Wolos JA, Frondorf KA, Esser RE. 1993. Immunosuppression mediated by an inhibitor of S-adenosyl-L-homocysteine hydrolase. Prevention and treatment of collagen-induced arthritis. J Immunol 151:526-534.
15. Wolos JA, Frondorf KA, Babcock GF, Stripp SA, Bowlin TL. 1993. Immunomodulation by an inhibitor of S-adenosyl-L-homocysteine hydrolase: inhibition of in vitro and in vivo allogeneic responses. Cell Immunol 149:402-408.
16. Miller MW, Duhl DM, Winkes BM, Arredondo-Vega F, Saxon PJ, et al. 1994. The mouse lethal nonagouti (a(x)) mutation deletes the S-adenosylhomocysteine hydrolase (Ahcy) gene. Embo J 13:1806-1816.
17. Seshadri S, Beiser A, Selhub J, Jacques PF, Rosenberg IH, et al. 2002. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med 346:476-483.
18. Nygard O, Nordrehaug JE, Refsum H, Ueland PM, Farstad M, et al. 1997. Plasma homocysteine levels and mortality in patients with coronary artery disease. N Engl J Med 337:230-236.
19. Loscalzo J. 2006. Homocysteine trials-clear outcomes for complex reasons. N Engl J Med 354:1629-1632.
20. Baric I, Cuk M, Fumic K, Vugrek O, Allen RH, et al. 2005. S-Adenosylhomocysteine hydrolase deficiency: a second patient, the younger brother of the index patient, and outcomes during therapy. J Inherit Metab Dis 28:885-902.
21. Buist NR, Glenn B, Vugrek O, Wagner C, Stabler S, et al. 2006. S-adenosylhomocysteine hydrolase deficiency in a 26-year-old man. J Inherit Metab Dis 29(4) 538-545.
22. Baric I, Fumic K, Glenn B, Cuk M, Schulze A, et al. 2004. S-adenosylhomocysteine hydrolase deficiency in a human: a genetic disorder of methionine metabolism. Proc Natl Acad Sci USA 101:4234-4239.
23. Beluzic R, Cuk M, Pavkov T, Baric I, Vugrek O. 2008. S- Adenosylhomocysteine hydrolase (AdoHcyase) deficiency: enzymatic capabilities of human AdoHcyase are highly effected by changes to codon 89 and its surrounding residues. Biochem Biophys Res Commun 368:30-36.
24. Bethin KE, Cimato TR, Ettinger MJ. 1995. Copper binding to mouse liver S-adenosylhomocysteine hydrolase and the effects of copper on its levels. J Biol Chem 270:20703-20711.
25. Bethin KE, Petrovic N, Ettinger MJ. 1995. Identification of a major hepatic copper binding protein as S-adenosylhomocysteine hydrolase. J Biol Chem 270:20698-20702.
26. Ault-Riche DB, Yuan CS, Borchardt RT. 1994. A single mutation at lysine 426 of human placental S-adenosylhomocysteine hydrolase inactivates the enzyme. J Biol Chem 269:31472-31478.
27. Ando H, Mizutani A, Kiefer H, Tsuzurugi D, Michikawa T, et al. 2006. IRBIT suppresses IP3 receptor activity by competing with IP3 for the common binding site on the IP3 receptor. Mol Cell 22:795-806.
28. Dekker JW, Budhia S, Angel NZ, Cooper BJ, Clark GJ, et al. 2002. Identification of an S-adenosylhomocysteine hydrolase-like transcript induced during dendritic cell differentiation. Immunogenetics 53:993-1001.
29. Devogelaere B, Beullens M, Sammels E, Derua R, Waelkens E, et al. 2007. Protein phosphatase-1 is a novel regulator of the interaction between IRBIT and the inositol 1,4,5-trisphosphate receptor. Biochem J 407:303-311.
30. Ashworth R, Devogelaere B, Fabes J, Tunwell RE, Koh KR, et al. 2007. Molecular and functional characterization of IP3 receptors during early zebrafish development. J Biol Chem 282:13984-13993.
31. Ando H, Mizutani A, Matsu-ura T, Mikoshiba K. 2003. IRBIT, a novel inositol 1,4,5-trisphosphate (IP3) receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptor. J Biol Chem 278:10602-10612.
32. Devogelaere B, Nadif Kasri N, Derua R, Waelkens E, Callewaert G, et al. 2006. Binding of IRBIT to the IP3 receptor: determinants and functional effects. Biochem Biophys Res Commun 343:49-56.
33. Collins MO, Yu L, Coba MP, Husi H, Campuzano I, et al. 2005. Proteomic analysis of in vivo phosphorylated synaptic proteins. J Biol Chem 280:5972-5982.
34. - cotransporter 1 (pNBC1). Proc Natl Acad Sci USA 103:9542-9547.
35. Tang TS, Tu H, Wang Z, Bezprozvanny I. 2003. Modulation of type 1 inositol (1,4,5)-trisphosphate receptor function by protein kinase a and protein phosphatase-1alpha. J Neurosci 23:403-415.
36. Tu H, Tang TS, Wang Z, Bezprozvanny I. 2004. Association of type 1 inositol 1,4,5-trisphosphate receptor with AKAP9 (Yotiao) and protein kinase A. J Biol Chem 279:19375-19382.
37. Devogelaere B, Verbert L, Parys JB, Missiaen L, De Smedt H. 2008. The complex regulatory function of the ligand-binding domain of the inositol 1,4,5-trisphosphate receptor. Cell Calcium 43:17-27.
38. Bultynck G, Heath VL, Majeed AP, Galan JM, Haguenauer-Tsapis R, et al. 2006. Slm1 and slm2 are novel substrates of the calcineurin phosphatase required for heat stress-induced endocytosis of the yeast uracil permease. Mol Cell Biol 26:4729-4745.
39. Park S, Uesugi M, Verdine GL. 2000. A second calcineurin binding site on the NFAT regulatory domain. Proc Natl Acad Sci USA 97:7130-7135.
40. 2+ signalling in apoptotic cell death. Calcium Binding Proteins 2:21-29.
41. Tompa P, Buzder-Lantos P, Tantos A, Farkas A, Szilagyi A, et al. 2004. On the sequential determinants of calpain cleavage. J Biol Chem 279:20775-20785.
42. Boehmerle W, Zhang K, Sivula M, Heidrich FM, Lee Y, et al. 2007. Chronic exposure to paclitaxel diminishes phosphoinositide signaling by calpain-mediated neuronal calcium sensor-1 degradation. Proc Natl Acad Sci USA 104:11103-11108.
43. Bujnicki JM, Prigge ST, Caridha D, Chiang PK. 2003. Structure, evolution, and inhibitor interaction of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum. Proteins 52:624-632.
44. Llorian M, Beullens M, Lesage B, Nicolaescu E, Beke L, et al. 2005. Nucleocytoplasmic shuttling of the splicing factor SIPP1. J Biol Chem 280:38862-38869.
45. Llorian M, Beullens M, Andres I, Ortiz JM, Bollen M. 2004. SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1. Biochem J 378:229-238.
46. 2+ release channels. Physiol Rev 87:593-658.
47. Sienaert I, Nadif Kasri N, Vanlingen S, Parys JB, Callewaert G, et al. 2002. Localization and function of a calmodulin-apocalmodulin-binding domain in the N-terminal part of the type 1 inositol 1,4,5-trisphosphate receptor. Biochem J 365:269-277.
48. 2+ and calmodulin. J Biol Chem 274:12157-12162.
49. Banizs B, Komlosi P, Bevensee MO, Schwiebert EM, Bell PD, et al. 2007. Altered pH(i) regulation and Na(+)/HCO3(-) transporter activity in choroid plexus of cilia-defective Tg737(orpk) mutant mouse. Am J Physiol Cell Physiol 292:C1409-1416.
50. 3- cotransporter from rat kidney. Am J Physiol 274:F425-F432.
51. Abuladze N, Lee I, Newman D, Hwang J, Boorer K, et al. 1998. Molecular cloning, chromosomal localization, tissue distribution, and functional expression of the human pancreatic sodium bicarbonate cotransporter. J Biol Chem 273:17689-17695.
52. - cotransporter. J Biol Chem 272:19111-19114.
53. - cotransporter. J Biol Chem 273:16810-16815.
54. Gill HS, Boron WF. 2006. Expression and purification of the cytoplasmic N-terminal domain of the Na/HCO3 cotransporter NBCe1-A: structural insights from a generalized approach. Protein Expr Purif 49:228-234.
55. +/HCO(3-) cotransporters (NBC): cloning and characterization. J Membr Biol 183:71-84.
56. +-coupled bicarbonate transporters NBCn1, NDCBE and NCBE. Faseb J.
57. +-coupled bicarbonate transporter NCBE by sequestering an N-terminal autoinhibitory domain. Faseb J.
58. Yuan CS, Ault-Riche DB, Borchardt RT. 1996. Chemical modification and site-directed mutagenesis of cysteine residues in human placental S-adenosylhomocysteine hydrolase. J Biol Chem 271:28009-28016.
59. Turner MA, Yang X, Yin D, Kuczera K, Borchardt RT, et al. 2000. Structure and function of S-adenosylhomocysteine hydrolase. Cell Biochem Biophys 33:101-125.
60. Hu Y, Komoto J, Huang Y, Gomi T, Ogawa H, et al. 1999. Crystal structure of S-adenosylhomocysteine hydrolase from rat liver. Biochemistry 38:8323-8333.
61. Gupta RA, Yuan CS, Ault-Riche DB, Borchardt RT. 1995. Limited proteolysis of S-adenosylhomocysteine hydrolase: implications for the three-dimensional structure. Arch Biochem Biophys 319:365-371.
62. Radomski N, Kaufmann C, Dreyer C. 1999. Nuclear accumulation of S-adenosylhomocysteine hydrolase in transcriptionally active cells during development of Xenopus laevis. Mol Biol Cell 10:4283-4298.
63. Mellman I, Steinman RM. 2001. Dendritic cells: specialized and regulated antigen processing machines. Cell 106:255-258.
64. Lewis RS, Cahalan MD. 1995. Potassium and calcium channels in lymphocytes. Annu Rev Immunol 13:623-653.
65. Baixeras E, Kroemer G, Cuende E, Marquez C, Bosca L, et al. 1993. Signal transduction pathways involved in B-cell induction. Immunol Rev 132:5-47.
66. Koski GK, Schwartz GN, Weng DE, Czerniecki BJ, Carter C, et al. 1999. Calcium mobilization in human myeloid cells results in acquisition of individual dendritic cell-like characteristics through discrete signaling pathways. J Immunol 163:82-92.
67. Bagley KC, Abdelwahab SF, Tuskan RG, Lewis GK. 2004. Calcium signaling through phospholipase C activates dendritic cells to mature and is necessary for the activation and maturation of dendritic cells induced by diverse agonists. Clin Diagn Lab Immunol 11:77-82.
68. Czerniecki BJ, Carter C, Rivoltini L, Koski GK, Kim HI, et al. 1997. Calcium ionophore-treated peripheral blood monocytes and dendritic cells rapidly display characteristics of activated dendritic cells. J Immunol 159:3823-3837.
69. 2+ entry pathway. J Immunol 166:6126-6133.
70. Andrei C, Margiocco P, Poggi A, Lotti LV, Torrisi MR, et al. 2004. Phospholipases C and A2 control lysosome-mediated IL-1 beta secretion: Implications for inflammatory processes. Proc Natl Acad Sci USA 101:9745-9750.
71. O'Connell PJ, Wang X, Leon-Ponte M, Griffiths C, Pingle SC, et al. 2006. A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cells. Blood 107:1010-1017.
72. Gardella S, Andrei C, Poggi A, Zocchi MR, Rubartelli A. 2000. Control of interleukin-18 secretion by dendritic cells: role of calcium influxes. FEBS Lett 481:245-248.
73. Rubartelli A, Poggi A, Zocchi MR. 1997. The selective engulfment of apoptotic bodies by dendritic cells is mediated by the alpha(v)beta3 integrin and requires intracellular and extracellular calcium. Eur J Immunol 27:1893-1900.
74. Dieu MC, Vanbervliet B, Vicari A, Bridon JM, Oldham E, et al. 1998. Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites. J Exp Med 188:373-386.
75. Yanagihara S, Komura E, Nagafune J, Watarai H, Yamaguchi Y. 1998. EBI1/CCR7 is a new member of dendritic cell chemokine receptor that is up-regulated upon maturation. J Immunol 161:3096-3102.
76. Montes M, McIlroy D, Hosmalin A, Trautmann A. 1999. Calcium responses elicited in human T cells and dendritic cells by cell-cell interaction and soluble ligands. Int Immunol 11:561-568.
77. Chan VW, Kothakota S, Rohan MC, Panganiban-Lustan L, Gardner JP, et al. 1999. Secondary lymphoid-tissue chemokine (SLC) is chemotactic for mature dendritic cells. Blood 93:3610-3616.
78. Delgado E, Finkel V, Baggiolini M, Mackay CR, Steinman RM, et al. 1998. Mature dendritic cells respond to SDF-1, but not to several beta-chemokines. Immunobiology 198:490-500.
79. Herrmann TL, Morita CT, Lee K, Kusner DJ. 2005. Calmodulin kinase II regulates the maturation and antigen presentation of human dendritic cells. J Leukoc Biol 78:1397-1407.
80. 2+ signaling in the absence of RyR1. J Leu Biol 80:651-658.
81. McLellan A, Heldmann M, Terbeck G, Weih F, Linden C, et al. 2000. MHC class II and CD40 play opposing roles in dendritic cell survival. Eur J Immunol 30:2612-2619.
82. Nihei OK, de Carvalho AC, Savino W, Alves LA. 2000. Pharmacologic properties of P(2Z)/P2X(7) receptor characterized in murine dendritic cells: role on the induction of apoptosis. Blood 96:996-1005.