Calcium Signaling through Phospholipase C Activates Dendritic Cells to Mature and Is Necessary for the Activation and Maturation of Dendritic Cells Induced by Diverse Agonists

Clinical and Diagnostic Laboratory Immunology

Volumn 11, Issue 1, 2004, Pages 77-82

  Bagley, Kenneth C ^a,b   Abdelwahab, Sayed F ^a,b   Tuskan, Robert G ^a   Lewis, George K ^a,b  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN; BACTERIUM LIPOPOLYSACCHARIDE; BUCLADESINE; CALCIMYCIN; CALCIUM; CALCIUM IONOPHORE; CHOLERA TOXIN; CYCLOSPORIN; CYTOKINE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; LIPOPOLYSACCHARIDE; PHOSPHOLIPASE C; PROSTAGLANDIN DERIVATIVE; PROSTAGLANDIN E2; TRICYCLO[4.3.0.1]DECAN 9 YL XANTHOGENATE; UNCLASSIFIED DRUG; XESTOSPONGIN;

ARTICLE; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CELL ACTIVATION; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MONOCYTE; MUSCLE CONTRACTION; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; SECOND MESSENGER; SIGNAL TRANSDUCTION; STIMULUS RESPONSE;

BUCLADESINE; CALCIMYCIN; CALCIUM SIGNALING; CELL DIFFERENTIATION; CHOLERA TOXIN; DENDRITIC CELLS; DINOPROSTONE; HUMANS; LIPOPOLYSACCHARIDES; PHOSPHOLIPASE C; THAPSIGARGIN;

EID: 0347128370     PISSN: 1071412X     EISSN: None     Source Type: Journal    
DOI: 10.1128/CDLI.11.1.77-82.2004     Document Type: Article

References (19)

1. Ardeshna, K. M., A. R. Pizzey, S. Devereux, and A. Khwaja. 2000. The P13 kinase, p38 SAP kinase, and NF-kappaB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells. Blood 96:1039-1046.
2. Bagley, K. C., S. F. Ahdelwahab, R. G. Tuskan, T. R. Fouts, and G. K. Lewis. 2002. Cholera toxin and heat-labile enterotoxin activate human monocyte-derived dendritic cells and dominantly inhibit cytokine production through a cyclic AMP-dependent pathway. Infect. Immun. 70:5533-5539.
3. Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392:245-252.
4. Cassel, D., and Z. Selinger. 1977. Mechanism of adenylate cyclase activation by cholera toxin: inhibition of GTP hydrolysis at the regulatory site. Proc. Natl. Acad. Sci. USA 74:3307-3311.
5. Czerniecki, B. J., C. Carter, L. Rivoltini, G. K. Koski, H. I. Kim, D. E. Weng, J. G. Roros, Y. M. Hijazi, S. Xu, S. A. Rosenherg, and P. A. Cohen. 1997. Calcium ionophore-treated peripheral blood monocytes and dendritic cells rapidly display characteristics of activated dendritic cells. J. Immunol. 159:3823-3837.
6. Dauer, M., B. Obermaier, J. Herten, C. Haerle, K. Pohl, S. Rothenfusser, M. Schnurr, S. Endres, and A. Eigler. 2003. Mature dendritic cells derived from human monocytes within 48 hours: a novel strategy for dendritic cell differentiation from blood precursors. J. Immunol. 170:4069-4076.
7. Endo, M., M. Tanaka, and Y. Ogawa. 1970. Calcium induced release of calcium from the sarcoplasmic reticulum of skinned skeletal muscle fibres. Nature 228:34-36.
8. Faries, M. B., I. Bedrosian, S. Xu, G. Koski, J. G. Roros, M. A. Moise, H. Q. Nguyen, F. H. Engels, P. A. Cohen, and B. J. Czerniecki. 2001. Calcium signaling inhibits interleukin-12 production and activates CD83(+) dendritic cells that induce Th2 cell development. Blood 98:2489-2497.
9. Gafni, J., J. A. Munsch, T. H. Lam, M. C. Catlin, L. G. Costa, T. F. Molinski, and I. N. Pessah. 1997. Xestospongins: potent membrane permeable blockers of the inositol 1,4,5-trisphosphate receptor. Neuron 19:723-733.
10. Hazes, B., and R. J. Read. 1997. Accumulating evidence suggests that several AB-toxins subvert the endoplasmic reticulum-associated protein degradation pathway to enter target cells. Biochemistry 36:11051-11054.
11. Heyningen, S. V. 1974. Cholera toxin: interaction of subunits with ganglio-side GM1. Science 183:656-657.
12. Koski, G. K., G. N. Schwartz, D. E. Weng, B. J. Czerniecki, C. Carter, R. E. Gress, and P. A. Cohen. 1999. Calcium mobilization in human myeloid cells results in acquisition of individual dendritic cell-like characteristics through discrete signaling pathways. J. Immunol. 163:82-92.
13. Muller-Decker, K. 1989. Interruption of TPA-induced signals by an antiviral and antitumoral xanthate compound: inhibition of a phospholipase C-type reaction. Biochem. Biophys. Res. Commun. 162:198-205.
14. Ohtomo, N., T. Muraoka, A. Tashiro, Y. Zinnaka, and K. Amako. 1976. Size and structure of the cholera toxin molecule and its subunits. J. Infect. Dis. 133(Suppl.):31-40.
15. Rieser, C., G. Bock, H. Klocker, G. Bartsch, and M. Thurnher. 1997. Prostaglandin E2 and tumor necrosis factor alpha cooperate to activate human dendritic cells: synergistic activation of interleukin 12 production. J. Exp. Med. 186:1603-1608.
16. Sallusto, F., and A. Lanzavecchia. 1994. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med. 179:1109-1118.
17. Takahashi, T., K. Fukuda, J. Pan, H. Kodama, M. Sano, S. Makino, T. Kato, T. Manabe, and S. Ogawa. 1999. Characterization of insulin-like growth factor-1-induced activation of the JAK/STAT pathway in rat cardiomyocytes. Circ. Res. 85:884-891.
18. Thastrup, O., H. Linnebjerg, P. J. Bjerrum, J. B. Knudsen, and S. B. Christensen. 1987. The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations. Biochim. Biophys. Acta 927:65-73.
19. Wilson, B. A., X. Zhu, M. Ho, and L. Lu. 1997. Pasteurella multocida toxin activates the inositol triphosphate signaling pathway in Xenopus oocytes via G(q)alpha-coupled phospholipase C-beta1. J. Biol. Chem. 272:1268-1275.