Computational prediction of ion permeation characteristics in the glycine receptor modified by photo-sensitive compounds

Journal of Computer-Aided Molecular Design

Volumn 22, Issue 8, 2008, Pages 563-570

  Cheng, Mary Hongying ^a   Coalson, Rob D ^a   Cascio, Michael ^b   Kurnikova, Maria ^c  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

Brownian dynamics; Computational modeling; Engineering glycine receptor; Lon permeation; Photo sensitive compound

Indexed keywords

AMINO ACIDS; ELECTRIC RECTIFIERS; EXCITED STATES; IONS;

BROWNIAN DYNAMICS; COMPUTATIONAL MODELLING; COMPUTATIONAL PREDICTIONS; ENGINEERING GLYCINE RECEPTOR; GLYCINE RECEPTOR; ION PERMEATION; LON PERMEATION; PERMEATION CHARACTERISTICS; PHOTO-SENSITIVE COMPOUND; SENSITIVE COMPOUNDS;

BROWNIAN MOVEMENT;

CHLORIDE ION; GLYCINE RECEPTOR; ION CHANNEL; SODIUM ION;

ARTICLE; CHANNEL GATING; CHEMICAL MODIFICATION; CONTROLLED STUDY; DIPOLE; DISSOCIATION; EQUIPMENT DESIGN; HYPOTHESIS; ILLUMINATION; ION PERMEABILITY; ION TRANSPORT; LIGHT; MATHEMATICAL ANALYSIS; MATHEMATICAL COMPUTING; MONTE CARLO METHOD; PHOTOACTIVATION; PHOTOSENSITIVITY; PREDICTION; PRIORITY JOURNAL; SIMULATION;

EID: 46049098788     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-008-9200-0     Document Type: Article

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