Epidemiology of multiresistant Gram-positive infections;Epidemiología de las infecciones por grampositivos multirresistentes

Enfermedades Infecciosas y Microbiologia Clinica

Volumn 26, Issue SUPPL. 2, 2008, Pages 4-12

  Sánchez, Fernando Chaves ^a   Daskalaki, Maria ^a   Otero, Joaquín R ^a  

^a HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

Author keywords

Coagulase negative staphylococci; Epidemiology; Resistance; Staphylococcus aureus; Vancomycin resistant enterococcus

Indexed keywords

AMPICILLIN; ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; CIPROFLOXACIN; CLINDAMYCIN; ERYTHROMYCIN; GENTAMICIN; LINEZOLID; PANTON VALENTINE LEUKOCIDIN; TEICOPLANIN; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; BACTERIAL INFECTION; COAGULASE NEGATIVE STAPHYLOCOCCUS; ENTEROCOCCUS; ENTEROCOCCUS FAECIUM; GRAM POSITIVE BACTERIUM; HOSPITAL INFECTION; HUMAN; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MOLECULAR EPIDEMIOLOGY; MULTIDRUG RESISTANCE; PREVALENCE; REVIEW; STAPHYLOCOCCUS AUREUS;

EID: 46049089283     PISSN: 0213005X     EISSN: 15781852     Source Type: Journal    
DOI: 10.1157/13114388     Document Type: Article

References (125)

1. Jevons MP. Celbenin-resistant Staphylococci. BMJ. 1961;i:124-25.
2. Grundmann H, Aires-de-Sousa M, Boyce J, Tiemersma E. Emergence and resurgence of meticillin-resistant Staphylococcus aureus as a public-health threat. Lancet. 2006;368:874-85.
3. Trallero EP, Arenzana JG, Castaneda AA, Grisolia LP. Unusual multiresistant Staphylococcus aureus in a newborn nursery. Am J Dis Child. 1981;135:689-92.
4. Parras F, Rodriguez M, Bouza E, Muñoz P, Cercenado E, Guerrero C, et al. Epidemic outbreak of methicillin-resistant Staphylococcus aureus in a general hospital. Preliminary report. Enferm Infecc Microbiol Clin. 1991;9:200-207.
5. Trilla A, Marco F, Moreno A, Prat A, Soriano E, Jimenez de Anta MT. Clinical epidemiology of an outbreak of nosocomial infection caused by Staphylococcus aureus resistant to methicillin and aminoglycosides: efficacy of control measures. Comité de Control de Infecciones. Med Clin (Barc). 1993;100:205-9.
6. Hiramatsu K, Hanaki H, Ino T, Yabuta K, Oguri T, Tenover FC. Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility. J Antimicrob Chemother. 1997;40:135-6.
7. Vancomycin-resistant Staphylococcus aureus: New York, 2004. MMWR Morb Mortal Wkly Rep. 2004;53:322-3.
8. Staphylococcus aureus resistant to vancomycin: United States, 2002. MMWR Morb Mortal Wkly Rep. 2002;51:565-7.
9. Katayama Y, Ito T, Hiramatsu K. A new class of genetic element, Staphylococcus cassette chromosome mec, encodes methicillin resistance in Staphylococcus aureus. Antimicrob Agents Chemother. 2000;44:1549-55.
10. Kuroda M, Ohta T, Uchiyama I, Baba T, Yuzawa H, Kobayashi I, et al. Whole genome sequencing of meticillin-resistant Staphylococcus aureus. Lancet. 2001;357:1225-40.
11. Ito T, Okuma K, Ma XX, Yuzawa H, Hiramatsu K. Insights on antibiotic resistance of Staphylococcus aureus from its whole genome: genomic island SCC. Drug Resist Updat. 2003;6:41-52.
12. Leclercq R. Mechanisms of resistance to macrolides and lincosamides: nature of the resistance elements and their clinical implications. Clin Infect Dis. 2002;34:482-92.
13. Katayama Y, Ito T, Hiramatsu K. Genetic organization of the chromosome region surrounding mecA in clinical staphylococcal strains: role of IS431-mediated mecI deletion in expression of resistance in mecA-carrying, low-level methicillin-resistant Staphylococcus haemolyticus. Antimicrob Agents Chemother. 2001;45:1955-63.
14. Ito T, Okuma K, Ma XX, Yuzawa H, Hiramatsu K. Insights on antibiotic resistance of Staphylococcus aureus from its whole genome: genomic island SCC. Drug Resist Updat. 2003;6:41-52.
15. Ito T, Katayama Y, Asada K, Mori N, Tsutsumimoto K, Tiensasitorn C, et al. Structural comparison of three types of staphylococcal cassette chromosome mec integrated in the chromosome in methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2001;45:1323-36.
16. Ito T, Ma XX, Takeuchi F, Okuma K, Yuzawa H, Hiramatsu K. Novel type V staphylococcal cassette chromosome mec driven by a novel cassette chromosome recombinase, ccrC. Antimicrob Agents Chemother. 2004;48:2637-51.
17. Daum RS, Ito T, Hiramatsu K, Hussain F, Mongkolrattanothai K, Jamklang M, et al. A novel methicillin-resistance cassette in community-acquired methicillin-resistant Staphylococcus aureus isolates of diverse genetic backgrounds. J Infect Dis. 2002;186:1344-47.
18. Hiramatsu K, Cui L, Kuroda M, Ito T. The emergence and evolution of methicillin-resistant Staphylococcus aureus. Trends Microbiol. 2001;9:486-93.
19. Oliveira DC, Tomasz A, de Lencastre H. The evolution of pandemic clones of methicillin-resistant Staphylococcus aureus: identification of two ancestral genetic backgrounds and the associated mec elements. Microb Drug Resist. 2001;7:349-61.
20. Wu SW, de Lencastre H, Tomasz A. Recruitment of the mecA gene homologue of Staphylococcus sciuri into a tesistance determinant and expression of the resistant phenotype in Staphylococcus aureus. J Bacteriol. 2001;183:2417-24.
21. Wielders CL, Vriens MR, Brisse S, Graaf-Miltenburg LA, Troelstra A, Fleer A, et al. In-vivo transfer of mecA DNA to Staphylococcus aureus. Lancet. 2001;357:1674-5.
22. Wisplinghoff H, Rosato AE, Enright MC, Noto M, Craig W, Archer GL. Related clones containing SCCmec type iv predominate among clinically significant Staphylococcus epidermidis isolates. Antimicrob Agents Chemother. 2003;47:3574-9.
23. Wisplinghoff H, Bischoff T, Tallent SM, Seifert H, Wenzel RP, Edmond MB. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin Infect Dis. 2004;39:309-17.
24. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004. Am J Infect Control. 2004;32:470-85.
25. Cuevas O, Cercenado E, Vindel A, Guinea J, Sánchez-Conde M, Sánchez-Somolinos M, et al. Evolution of the antimicrobial resistance of Staphylococcus spp. in Spain: five nationwide prevalence studies, 1986 to 2002. Antimicrob Agents Chemother. 2004;48:4240-5.
26. Pujol M, Pena C, Pallarés R, Ayats J, Ariza J, Gudiol F. Risk factors for nosocomial bacteremia due to methicillin-resistant Staphylococcus aureus. Eur J Clin Microbiol Infect Dis. 1994;13:96-102.
27. Chaves F, García-Martínez J, de Miguel S, Sanz F, Otero JR. Epidemiology and clonality of methicillin-resistant and methicillin-susceptible Staphylococcus aureus causing bacteremia in a tertiary-care hospital in Spain. Infect Control Hosp Epidemiol. 2005;26:150-6.
28. García-Vázquez E, Gómez J, Banos R, Canteras M, Ruiz J, Banos V, et al. A comparative study of patients with methicillin susceptible versus methicillin resistant Staphylococcus aureus bacteremia: epidemiology and prognostic factors. Med Clin (Barc ). 2007;128:681-6.
29. Thompson RL, Cabezudo I, Wenzel RP. Epidemiology of nosocomial infections caused by methicillin-resistant Staphylococcus aureus. Ann Intern Med. 1982;97:309-17.
30. Benner EJ, Kayser FH. Growing clinical significance of methcillin-resistant Staphylococcus aureus. Lancet. 1968;2:741-4.
31. Rountree PM, Beard MA. Hospital strains of Staphylococcus aureus, with particular reference to methicillin-resistant strains. Med J Aust. 1968;2:1163-8.
32. Jessen O, Rosendal K, Bulow P, Faber V, Eriksen KR. Changing staphylococci and staphylococcal infections. A ten-year study of bacteria and cases of bacteremia. N Engl J Med. 1969;281:627-35.
33. Parker MT, Hewitt JH. Methicillin resistance in Staphylococcus aureus. Lancet. 1970;1:800-804.
34. Tomasz A. Accelerated evolution: emergence of multidrug resistant gram-positive bacterial pathogens in the 1990's. Neth J Med. 1998;52:219-27.
35. Lowy FD. Antimicrobial resistance: the example of Staphylococcus aureus. J Clin Invest. 2003;111:1265-73.
36. Dominguez MA, de Lencastre H, Linares J, Tomasz A. Spread and maintenance of a dominant methicillin-resistant Staphylococcus aureus (MRSA) clone during an outbreak of MRSA disease in a Spanish hospital. J Clin Microbiol. 1994;32:2081-7.
37. Aparicio P, Richardson J, Martin S, Vindel A, Marples RR, Cookson BD. An epidemic methicillin-resistant strain of Staphylococcus aureus in Spain. Epidemiol Infect. 1992;108:287-98.
38. Vindel A, Trincado P, Gómez E, Cabrera R, Boquete T, Sola C, et al. Prevalence and evolution of methicillin-resistant Staphylococcus aureus in Spanish hospitals between 1996 and 2002. J Clin Microbiol. 2006;44:266-70.
39. Perez-Roth E, Lorenzo-Diaz F, Batista N, Moreno A, Mendez-Alvarez S. Tracking methicillin-resistant Staphylococcus aureus clones during a 5-year period (1998 to 2002) in a Spanish hospital. J Clin Microbiol. 2004;42:4649-56.
40. Montesinos I, Delgado T, Riverol D, Salido E, Miguel MA, Jimenez A, et al. Changes in the epidemiology of meticillin-resistant Staphylococcus aureus associated with the emergence of EMRSA-16 at a university hospital. J Hosp Infect. 2006;64:257-63.
41. Alcoceba E, Mena A, Cruz PM, Ruiz G, Padilla E, Gil J, et al. Molecular epidemiology of methicillin-resistant Staphylococcus aureus in Majorcan hospitals: high prevalence of the epidemic clone EMRSA-15. Clin Microbiol Infect. 2007;13:599-605.
42. Nicolle LE, Strausbaugh LJ, Garibaldi RA. Infections and antibiotic resistance in nursing homes. Clin Microbiol Rev. 1996;9:1-17.
43. Suetens C, Niclaes L, Jans B, Verhaegen J, Schuermans A, van Eldere J, et al. Determinants of methicillin-resistant Staphylococcus aureus carriage in nursing homes. Age Ageing. 2007;36:327-30.
44. Von Baum H, Schmidt C, Svoboda D, Bock-Hensley O, Wendt C. Risk factors for methicillin-resistant Staphylococcus aureus carriage in residents of German nursing homes. Infect Control Hosp Epidemiol. 2002;23:511-5.
45. Crossley K. Long-term care facilities as sources of antibiotic-resistant nosocomial pathogens. Curr Opin Infect Dis. 2001;14:455-9.
46. O'Toole RD, Drew WL, Dahlgren BJ, Beaty HN. An outbreak of methicillin-resistant Staphylococcus aureus infection. Observations in hospital and nursing home. JAMA. 1970;213:257-63.
47. Cox RA, Bowie PE. Methicillin-resistant Staphylococcus aureus colonization in nursing home residents: a prevalence study in Northamptonshire. J Hosp Infect. 1999;43:115-22.
48. Saravolatz LD, Markowitz N, Arking L, Pohlod D, Fisher E. Methicillin-resistant Staphylococcus aureus. Epidemiologic observations during a community-acquired outbreak. Ann Intern Med. 1982;96:11-6.
49. Udo EE, Pearman JW, Grubb WB. Genetic analysis of community isolates of methicillin-resistant Staphylococcus aureus in Western Australia. J Hosp Infect. 1993;25:97-108.
50. Center for Disease Control and Prevention. Four pedriatic deaths from community acquired MRSA-Minnesota and North Dakota,1997-1999. MMWR Morb Mortal Wkly Rep. 1999;48:707-10.
51. Lina G, Piemont Y, Godail-Gamot F, Bes M, Peter MO, Gauduchon V, et al. Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin Infect Dis. 1999;29:1128-32.
52. Naimi TS, LeDell KH, Boxrud DJ, Groom AV, Steward CD, Johnson SK, et al. Epidemiology and clonality of community-acquired methicillin-resistant Staphylococcus aureus in Minnesota, 1996-1998. Clin Infect Dis. 2001;33:990-6.
53. Center for Disease Control and Prevention. Outbreaks of community-associated methicillin-resistant Staphylococcus aureus skin infections - Los Angeles County, California, 2002-2003. MMWR Morb Mortal Wkly Rep. 2003;52:88.
54. Buckingham SC, McDougal LK, Cathey LD, Comeaux K, Craig AS, Fridkin SK, et al. Emergence of community-associated methicillin-resistant Staphylococcus aureus at a Memphis, Tennessee Children's Hospital. Pediatr Infect Dis J. 2004;23:619-24.
55. Kaplan SL, Hulten KG, Gonzalez BE, Hammerman WA, Lamberth L, Versalovic J, et al. Three-year surveillance of community-acquired Staphylococcus aureus infections in children. Clin Infect Dis. 2005;40:1785-91.
56. Regev-Yochay G, Rubinstein E, Barzilai A, Carmeli Y, Kuint J, Etienne J, et al. Methicillin-resistant Staphylococcus aureus in neonatal intensive care unit. Emerg Infect Dis. 2005;11:453-6.
57. Broseta A, Chaves F, Rojo P, Otero JR. Emergence of a single clone of community-associated methicillin-resistant Staphylococcus aureus in southern Madrid children. Enferm Infecc Microbiol Clin. 2006;24:31-5.
58. Naimi TS, LeDell KH, Como-Sabetti K, Borchardt SM, Boxrud DJ, Etienne J, et al. Comparison of community- and health care-associated methicillin-resistant Staphylococcus aureus infection. JAMA. 2003;290:2976-84.
59. Okuma K, Iwakawa K, Turnidge JD, Grubb WB, Bell JM, O'Brien FG. et al. Dissemination of new methicillin-resistant Staphylococcus aureus clones in the community. J Clin Microbiol. 2002;40:4289-94.
60. Ma XX, Ito T, Tiensasitorn C, Jamklang M, Chongtrakool P, Boyle-Vavra S. et al. Novel type of staphylococcal cassette chromosome mec identified in community-acquired methicillin-resistant Staphylococcus aureus strains. Antimicrob Agents Chemother. 2002;46:1147-52.
61. Vandenesch F, Naimi T, Enright MC, Lina G, Nimmo GR, Heffernan H, et al. Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence. Emerg Infect Dis. 2003;9:978-84.
62. Etienne J. Panton-Valentine leukocidin: a marker of severity for Staphylococcus aureus infection? Clin Infect Dis. 2005;41:591-3.
63. Gillet Y, Issartel B, Vanhems P, Fournet JC, Lina G, Bes M, et al. Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients. Lancet. 2002;359:753-9.
64. Labandeira-Rey M, Couzon F, Boisset S, Brown EL, Bes M, Benito Y, et al. Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia. Science. 2007;315:1130-3.
65. Voyich JM, Otto M, Mathema B, Braughton KR, Whitney AR, Welty D, et al. Is Panton-Valentine leukocidin the major virulence determinant in community-associated methicillin-resistant Staphylococcus aureus disease? J Infect Dis. 2006;194:1761-70.
66. Dumitrescu O, Boisset S, Badiou C, Bes M, Benito Y, Reverdy ME, et al. Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin. Antimicrob Agents Chemother. 2007;51:1515-9.
67. Carleton HA, Diep BA, Charlebois ED, Sensabaugh GF, Perdreau-Remington F. Community-adapted methicillin-resistant Staphylococcus aureus (MRSA): population dynamics of an expanding community reservoir of MRSA. J Infect Dis. 2004;190:1730-8.
68. Salgado CD, Farr BM, Calfee DP. Community-acquired methicillin-resistant Staphylococcus aureus: a meta-analysis of prevalence and risk factors. Clin Infect Dis. 2003;36:131-9.
69. Deurenberg RH, Vink C, Kalenic S, Friedrich AW, Bruggeman CA, Stobberingh EE. The molecular evolution of methicillin-resistant Staphylococcus aureus. Clin Microbiol Infect. 2007;13:222-35.
70. Deresinski S. Methicillin-resistant Staphylococcus aureus: an evolutionary, epidemiologic, and therapeutic odyssey. Clin Infect Dis. 2005;40:562-73.
71. Robinson DA, Enright MC. Evolutionary models of the emergence of methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2003;47:3926-34.
72. Kluytmans-Vandenbergh MF, Kluytmans JA. Community-acquired methicillin-resistant Staphylococcus aureus: current perspectives. Clin Microbiol Infect. 2006;12 Suppl1:9-15.
73. Sa-Leao R, Sanches IS, Couto I, Alves CR, De Lencastre H. Low prevalence of methicillin-resistant strains among Staphylococcus aureus colonizing young and healthy members of the community in Portugal. Microb Drug Resist. 2001;7:237-45.
74. Fridkin SK, Hageman JC, Morrison M, Sanza LT, Como-Sabetti K, Jernigan JA, et al. Methicillin-resistant Staphylococcus aureus disease in three communities. N Engl J Med. 2005;352:1436-44.
75. Baggett HC, Hennessy TW, Rudolph K, Bruden D, Reasonover A, Parkinson A, et al. Community-onset methicillin-resistant Staphylococcus aureus associated with antibiotic use and the cytotoxin Panton-Valentine leukocidin during a furunculosis outbreak in rural Alaska. J Infect Dis. 2004;189:1565-73.
76. Kazakova SV, Hageman JC, Matava M, Srinivasan A, Phelan L, Garfinkel B, et al. A clone of methicillin-resistant Staphylococcus aureus among professional football players. N Engl J Med. 2005;352:468-75.
77. Zinderman CE, Conner B, Malakooti MA, LaMar JE, Armstrong A, Bohnker BK. Community-acquired methicillin-resistant Staphylococcus aureus among military recruits. Emerg Infect Dis. 2004;10:941-4.
78. Bratu S, Eramo A, Kopec R, Coughlin E, Ghitan M, Yost R, et al. Community-associated methicillin-resistant Staphylococcus aureus in hospital nursery and maternity units. Emerg Infect Dis. 2005;11:808-13.
79. Seybold U, Kourbatova EV, Johnson JG, Halvosa SJ, Wang YF, King MD, et al. Emergence of community-associated methicillin-resistant Staphylococcus aureus USA300 genotype as a major cause of health care-associated blood stream infections. Clin Infect Dis. 2006;42:647-56.
80. Kourbatova EV, Halvosa JS, King MD, Ray SM, White N, Blumberg HM. Emergence of community-associated methicillin-resistant Staphylococcus aureus USA 300 clone as a cause of health care-associated infections among patients with prosthetic joint infections. Am J Infect Control. 2005;33:385-91.
81. Tristan A, Bes M, Meugnier H, Lina G, Bozdogan B, Courvalin P, et al. Global distribution of Panton-Valentine leukocidin-positive methicillin- resistant Staphylococcus aureus, 2006. Emerg Infect Dis. 2007;13:594-600.
82. Kloos WE, Bannerman TL. Update on clinical significance of coagulase-negative staphylococci. Clin Microbiol Rev. 1994;7:117-40.
83. Von Eiff C, Peters G, Heilmann C. Pathogenesis of infections due to coagulase-negative staphylococci. Lancet Infect Dis. 2002;2:677-85.
84. Bannerman TL. Staphylococcus, Micrococcus, and other catalase-positive cocci that grow aerobically. En: Murray PE, Baron EJ, Jorgensen JJ, Pfaller MA, Yolken RH, editors. Manual of clinical microbiology. 8th ed. Washington: American Society for Microbiology; 2007. p. 384-404.
85. Rupp ME, Archer GL. Coagulase-negative staphylococci: pathogens associated with medical progress. Clin Infect Dis. 1994;19:231-43.
86. Karlowsky JA, Jones ME, Draghi DC, Thornsberry C, Sahm DF, Volturo GA. Prevalence and antimicrobial susceptibilities of bacteria isolated from blood cultures of hospitalized patients in the United States in 2002. Ann Clin Microbiol Antimicrob. 2004;3:7.
87. Weisman LE. Coagulase-negative staphylococcal disease: emerging therapies for the neonatal and pediatric patient. Curr Opin Infect Dis. 2004;17:237-41.
88. Venkatesh MP, Placencia F, Weisman LE. Coagulase-negative staphylococcal infections in the neonate and child: an update. Semin Pediatr Infect Dis. 2006;17:120-7.
89. Miragaia M, Couto I, Pereira SF, Kristinsson KG, Westh H, Jarlov JO, et al. Molecular characterization of methicillin-resistant Staphylococcus epidermidis clones: evidence of geographic dissemination. J Clin Microbiol. 2002;40:430-8.
90. Widerstrom M, Monsen T, Karlsson C, Wistrom J. Molecular epidemiology of meticillin-resistant coagulase-negative staphylococci in a Swedish county hospital: evidence of intra- and interhospital clonal spread. J Hosp Infect. 2006;64:177-83.
91. Krediet TG, Mascini EM, van Rooij E, Vlooswijk J, Paauw A, Gerards LJ, et al. Molecular epidemiology of coagulase-negative staphylococci causing sepsis in a neonatal intensive care unit over an 11-year period. J Clin Microbiol. 2004;42:992-5.
92. Van der Zwet WC, Debets-Ossenkopp YJ, Reinders E, Kapi M, Savelkoul PH, van Elburg RM, et al. Nosocomial spread of a Staphylococcus capitis strain with heteroresistance to vancomycin in a neonatal intensive care unit. J Clin Microbiol. 2002;40:2520-5.
93. Ross TL, Fuss EP, Harrington SM, Cai M, Perl TM, Merz WG. Methicillin-resistant Staphylococcus caprae in a neonatal intensive care unit. J Clin Microbiol. 2005;43:363-7.
94. Chaves F, García-Álvarez M, Sanz F, Alba C, Otero JR. Nosocomial spread of a Staphylococcus hominis subsp. novobiosepticus strain causing sepsis in a neonatal intensive care unit. J Clin Microbiol. 2005;43:4877-9.
95. Diekema DJ, Pfaller MA, Schmitz FJ, Smayevsky J, Bell J, Jones RN, et al. Survey of infections due to Staphylococcus species: frequency of occurrence and antimicrobial susceptibility of isolates collected in the United States, Canada, Latin America, Europe, and the Western Pacific region for the SENTRY Antimicrobial Surveillance Program, 1997-1999. Clin Infect Dis. 2001;32 Suppl 2:S114-32.
96. Murray BE. Vancomycin-resistant enterococcal infections. N Engl J Med. 2000;342:710-21.
97. Biavasco F, Vignaroli C, Varaldo PE. Glycopeptide resistance in coagulase-negative staphylococci. Eur J Clin Microbiol Infect Dis. 2000;19:403-17.
98. Cercenado E, Garcia-Leoni ME, Diaz MD, Sanchez-Carrillo C, Catalan P, de Quiros JC, et al. Emergence of teicoplanin-resistant coagulase-negative staphylococci. J Clin Microbiol. 1996;34:1765-8.
99. Reynolds R, Potz N, Colman M, Williams A, Livermore D, MacGowan A. Antimicrobial susceptibility of the pathogens of bacteraemia in the UK and Ireland 2001-2002: the BSAC Bacteraemia Resistance Surveillance Programme. J Antimicrob Chemother. 2004;53:1018-32.
100. Ross JE, Anderegg TR, Sader HS, Fritsche TR, Jones RN. Trends in linezolid susceptibility patterns in 2002: report from the worldwide Zyvox Annual Appraisal of Potency and Spectrum Program. Diagn Microbiol Infect Dis. 2005;52:53-8.
101. Potoski BA, Adams J, Clarke L, Shutt K, Linden PK, Baxter C, et al. Epidemiological profile of linezolid-resistant coagulase-negative staphylococci. Clin Infect Dis. 2006;43:165-71.
102. Martins Teixeira L, Facklam RR. Enterococcus. En: Murray PE, Baron EJ, Jorgensen JJ, Pfaller MA, Yolken RH, editors. Manual of clinical microbiology. 8th ed. Washington: American Society for Microbiology; 2007. p. 422-33.
103. Cetinkaya Y, Falk P, Mayhall CG. Vancomycin-resistant enterococci. Clin Microbiol Rev. 2000;13:686-707.
104. Clevel DB. Movable genetic elements and antibiotic resistance in enterococci. Eur J Clin Microbiol Infect Dis. 1990;9:90-102.
105. Murray BE. Beta-lactamase-producing enterococci. Antimicrob Agents Chemother. 1992;36:2355-9.
106. Fontana R, Bertolini G, Amalfitano G, Canepari P. Characterization of penicillin-resistant Streptococcus faecium mutants. FEMS Microbiol Lett. 1984;25:21-5.
107. Oteo J, Cuevas O, Navarro C, Aracil B, Campos J. Trends in antimicrobial resistance in 3469 enterococci isolated from blood (EARSS experience 2001-06, Spain): increasing ampicillin resistance in Enterococcus faecium. J Antimicrob Chemother. 2007;59:1044-5.
108. Uttley AH, Collins CH, Naidoo J, George RC. Vancomycin-resistant enterococci. Lancet. 1988;1:57-8.
109. Leclercq R, Derlot E, Duval J, Courvalin P. Plasmid-mediated resistance to vancomycin and teicoplanin in Enterococcus faecium. N Engl J Med. 1988;319:157-61.
110. Kaplan AH, Gilligan PH, Facklam RR. Recovery of resistant enterococci during vancomycin prophylaxis. J Clin Microbiol. 1988;26:1216-8.
111. Depardieu F, Bonora MG, Reynolds PE, Courvalin P. The vanG glycopeptide resistance operon from Enterococcus faecalis revisited. Mol Microbiol. 2003;50:931-48.
112. Stinear TP, Olden DC, Johnson PD, Davies JK, Grayson ML. Enterococcal vanB resistance locus in anaerobic bacteria in human faeces. Lancet. 2001;357:855-6.
113. Ballard SA, Pertile KK, Lim M, Johnson PD, Grayson ML. Molecular characterization of vanB elements in naturally occurring gut anaerobes. Antimicrob Agents Chemother. 2005;49:1688-94.
114. Domingo MC, Huletsky A, Bernal A, Giroux R, Boudreau DK, Picard FJ, et al. Characterization of a Tn5382-like transposon containing the vanB2 gene cluster in a Clostridium strain isolated from human faeces. J Antimicrob Chemother. 2005;55:466-74.
115. Guardabassi L, Christensen H, Hasman H, Dalsgaard A. Members of the genera Paenibacillus and Rhodococcus harbor genes homologous to enterococcal glycopeptide resistance genes vanA and vanB. Antimicrob Agents Chemother. 2004;48:4915-8.
116. Tenover FC, McDonald LC. Vancomycin-resistant staphylococci and enterococci: epidemiology and control. Curr Opin Infect Dis. 2005;18:300-5.
117. Warren DK, Nitin A, Hill C, Fraser VJ, Kollef MH. Occurrence of co-colonization or co-infection with vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus in a medical intensive care unit. Infect Control Hosp Epidemiol. 2004;25:99-104.
118. Deshpande LM, Fritsche TR, Moet GJ, Biedenbach DJ, Jones RN. Antimicrobial resistance and molecular epidemiology of vancomycin-resistant enterococci from North America and Europe: a report from the SENTRY antimicrobial surveillance program. Diagn Microbiol Infect Dis. 2007;58:163-70.
119. Leavis HL, Bonten MJ, Willems RJ. Identification of high-risk enterococcal clonal complexes: global dispersion and antibiotic resistance. Curr Opin Microbiol. 2006;9:454-60.
120. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004. Am J Infect Control. 2004;32:470-85.
121. Biedenbach DJ, Moet GJ, Jones RN. Occurrence and antimicrobial resistance pattern comparisons among bloodstream infection isolates from the SENTRY Antimicrobial Surveillance Program (1997-2002). Diagn Microbiol Infect Dis. 2004;50:59-69.
122. Willems RJ, Top J, van Santen M, Robinson DA, Coque TM, Baquero F, et al. Global spread of vancomycin-resistant Enterococcus faecium from distinct nosocomial genetic complex. Emerg Infect Dis. 2005;11:821-8.
123. Coque TM, Willems RJ, Fortun J, Top J, Diz S, Loza E, et al. Population structure of Enterococcus faecium causing bacteremia in a Spanish university hospital: setting the scene for a future increase in vancomycin resistance? Antimicrob Agents Chemother. 2005;49:2693-700.
124. Nallapareddy SR, Wenxiang H, Weinstock GM, Murray BE. Molecular characterization of a widespread, pathogenic, and antibiotic resistance-receptive Enterococcus faecalis lineage and dissemination of its putative pathogenicity island. J Bacteriol. 2005;187:5709-18.
125. Ruiz-Garbajosa P, Bonten MJ, Robinson DA, Top J, Nallapareddy SR, Torres C, et al. Multilocus sequence typing scheme for Enterococcus faecalis reveals hospital-adapted genetic complexes in a background of high rates of recombination. J Clin Microbiol. 2006;44:2220-8.