Particle generation for pharmaceutical applications using supercritical fluid technology

Powder Technology

Volumn 141, Issue 3, 2004, Pages 219-226

  Fages, Jacques ^a   Lochard, Hubert ^a   Letourneau, Jean Jacques ^a   Sauceau, Martial ^a   Rodier, Elisabeth ^a  

^a ECOLE DES MINES D ALBI CARMAUX   (France)

Author keywords

Particle generation; Pharmaceutical application; Supercritical fluid technology

Indexed keywords

CRYSTALLIZATION; DRUG PRODUCTS; DRUG PRODUCTS PLANTS; SOLVENTS; SUPERCRITICAL FLUIDS;

CRYSTAL POLYMORPHISM; PARTICLE GENERATION; PARTICULATE SOLIDS; SUPERCRITICAL ANTI SOLVENTS (SAS);

PARTICLE SIZE ANALYSIS;

AMOXICILLIN; ANTIBIOTIC AGENT; ASCORBIC ACID; BIOPOLYMER; CARBON DIOXIDE; CATALASE; CHLORAMPHENICOL; DEXTRAN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IBUPROFEN; INSULIN; INULIN; LYSOZYME; NAPROXEN; PEROXIDASE; POLYMER; RIFAMPICIN; SALBUTAMOL; SOLVENT; TETRACYCLINE DERIVATIVE; TRYPSIN;

MEDICAL APPLICATION;

ARTICLE; CRYSTALLIZATION; DECOMPRESSION; DRUG INDUSTRY; HYDRODYNAMICS; MATHEMATICAL COMPUTING; POWDER; PRESSURE; SOLUTE; SUPERCRITICAL FLUID; TECHNOLOGY; TEMPERATURE SENSITIVITY;

EID: 2642547178     PISSN: 00325910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.powtec.2004.02.007     Document Type: Article

References (27)

1. Roberts C.J., Debenedetti P.G. Engineering pharmaceutical stability with amorphous solids. AIChE J. 48:2002;1140-1144
2. Sauceau M., Fages J., Letourneau J.-J., Richon D. A novel apparatus for accurate measurements of solid solubilities in supercritical phases. Ind. Eng. Chem. Res. 39:2000;4609-4614
3. 2 and cosolvent: development of enhanced density-based models. Fluid Phase Equilib. 208:2003;99-113
4. 2: experimental results and calculation with Peng-Robinson equation of state. Proc. 8th Meeting on Supercritical Fluids, Bordeaux (France). vol. 2:2002;529-534 ISASF International Society for the Advancement of Supercritical Fluids, Nancy, France
5. Weber M., Russell L.M., Debenedetti P.G. Mathematical modeling of nucleation and growth of particles formed by the rapid expansion of a supercritical solution under subsonic conditions. J. Supercrit. Fluids. 23:2002;65-80
6. Tom J., Debenedetti P.G. Particle formation with supercritical fluids - a review. J. Aerosol Sci. 22:1991;555-584
7. Kwauk X., Debenedetti P.G. Mathematical modeling of aerosol formation by rapid expansion of supercritical solutions in a converging nozzle. J. Aerosol. Sci. 24:1993;445-469
8. Raynie D. Warning concerning the use of nitrous oxide in supercritical fluid extractions. Anal. Chem. 65:1993;3127-3128
9. Sauceau M., Letourneau J.-J., Freiss B., Richon D., Fages J. Solubility of Eflucimibe in supercritical carbon dioxide with or without a co-solvent. J. Supercrit. Fluids. 2004;. (in press)
10. Charoenchaitrakool M., Dehghani F., Foster N.R., Chan H.K. Micronization by rapid expansion of supercritical solutions to enhance the dissolution rates of poorly water soluble pharmaceuticals. Ind. Eng. Chem. Res. 39:2000;4794-4802
11. Jung J., Perrut M. Particle design using supercritical fluids: literature and patent survey. J. Supercrit. Fluids. 20:2001;179-219
12. Knutson B., Debenedetti P.G., Tom J. Preparation of microparticulates using supercritical fluids. Cohen S., Bernstein H. Microparticulate Systems for the Delivery of Proteins and Vaccines, Drugs and the Pharmaceutical Sciences Series. vol. 77:1996;89-125 Marcel Dekker, New York
13. Kim J.H., Paxton T.E., Tomasko D.L. Microencapsulation of naproxen using rapid expansion of supercritical solutions. Biotechnol. Prog. 12:1996;650-661
14. Mishima K., Matsuyama K., Tanabe D., Yamauchi S., Young T.J., Johnston K.P. Microencapsulation of proteins by rapid expansion of supercritical solution with a non-solvent. AIChE J. 46(4):2000;857-865
15. Richard J., Pech B., Thies C., Ribeiro dos Santos M.I., Benoit J.P. Preparation and characterisation of sustained-release microcapsules obtained using supercritical fluid technology. Proc. 7th Meeting on Supercritical Fluids, Antibes (France). vol. 1:2000;143-146 ISASF International Society for the Advancement of Supercritical Fluids, Nancy, France
16. Tsutsumi A., Nakamoto S., Mineo T., Yoshida K. A novel fluidized-bed coating of fine particles by rapid expansion of supercritical fluid solutions. Powder Technol. 85:1995;275-278
17. Reverchon E., de Marco I., della Porta G. Rifampicin microparticles production by supercritical antisolvent precipitation. Int. J. Pharmacogn. 243:2002;83-91
18. Shekunov B., Sun Y., Astracharchik E., York P., Baldyga J. Optical characterisation and mechanism of antisolvent precipitation in turbulent flow. Proc. 7th Meeting on Supercritical Fluids, Antibes (France). vol. 1:2000;65-70 ISASF International Society for the Advancement of Supercritical Fluids, Nancy, France
19. Rantakylä M., Jäntti M., Aaltonen O., Hurme M. The effect of initial drop size in the supercritical antisolvent precipitation (SAS) technique. J. Supercrit. Fluids. 24:2002;251-263
20. Lora M., Bertucco A., Kikic I. Simulation of the semi-continuous supercritical antisolvent recrystallization process. Ind. Eng. Chem. Res. 39:2000;1487-1496
21. Werling J.O., Debenedetti P.G. Numerical modeling of mass transfer in the supercritical antisolvent process: miscible conditions. J. Supercrit. Fluids. 18:2000;11-24
22. 2. Proc. 7th Meeting on Supercritical Fluids, Antibes (France). vol. 1:2000;117-122 ISASF International Society for the Advancement of Supercritical Fluids, Nancy, France
23. Palakodaty S., York P., Pritchard J. Supercritical fluid processing of materials from aqueous solutions: the application of SEDS to lactose as a model substance. Pharm. Res. 15:1998;1835-1843
24. Knez Z. Micronisation of pharmaceuticals using supercritical fluids. Proc. 7th Meeting on Supercritical Fluids, Antibes (France). vol. 1:2000;21-26 ISASF International Society for the Advancement of Supercritical Fluids, Nancy, France
25. Weidner E., Steiner R., Knez Z. Powder generation from polyethylene glycols with compressible fluids. Rudolph von Rohr P., Trepp C. High Pressure Chemical Engineering. 1996;223-228 Elsevier, Netherlands
26. Sievers R.E., Milewski P.D., Sellers S.P., Miules B.A., Korte B.J., Kusek K.D., Clack G.S., Mioskowski B., Villa J.A. Supercritical and near-critical carbon dioxide assisted low-temperature bubble drying. Ind. Eng. Chem. Res. 39:2000;, 4831-4836
27. Elvassore N., Kikic I. Pharmaceutical processing with supercritical fluids. Bertucco A., Vetter G. High Pressure Process Technology: Fundamentals and Applications. 2001;612-625 Elsevier, Netherlands