α1-adrenoceptors trigger the snake venom production cycle in secretory cells by activating phosphatidylinositol 4,5-bisphosphate hydrolysis and ERK signaling pathway

Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology

Volumn 150, Issue 4, 2008, Pages 431-437

  Kerchove, Celine M ^a   Luna, Milene S A ^a   Zablith, Mariana B ^a   Lazari, Maria F M ^b   Smaili, Soraya S ^b   Yamanouye, Norma ^a  

^a INSTITUTO BUTANTAN   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

ERK; Partial sequence; PIP2 hydrolysis; Snake; Venom gland; 1 adrenoceptor

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; ALPHA 1 ADRENERGIC RECEPTOR; BATROXOBIN; BETA ADRENERGIC RECEPTOR; CALCIUM; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHENYLEPHRINE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE C INHIBITOR; PROTEIN KINASE C; SNAKE VENOM; THAPSIGARGIN; 1 (6 ((3 METHOXYESTRA 1,3,5(10) TRIEN 17 YL)AMINO)HEXYL) 1H PYRROLE 2,5 DIONE; 1-(6-((3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL)-1H-PYRROLE-2,5-DIONE; 2 PYRROLIDONE DERIVATIVE; ENZYME INHIBITOR; ESTRANE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL STIMULATION; ENZYME ACTIVITY; EXTRACTION; FEMALE; HYDROLYSIS; MALE; MORPHOLOGY; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETORY CELL; SIGNAL TRANSDUCTION; SNAKE; ANIMAL; CHEMISTRY; METABOLISM; PHYSIOLOGY;

BOTHROPS JARARACA;

ANIMALS; BOTHROPS; CALCIUM; ENZYME INHIBITORS; ESTRENES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; MALE; MAP KINASE SIGNALING SYSTEM; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PROTEIN KINASE C; PYRROLIDINONES; RECEPTORS, ADRENERGIC, ALPHA-1; SIGNAL TRANSDUCTION; SNAKE VENOMS; THAPSIGARGIN;

EID: 45849143638     PISSN: 10956433     EISSN: 15314332     Source Type: Journal    
DOI: 10.1016/j.cbpa.2008.04.607     Document Type: Article

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