Role of TNF-α in ileum tight junction alteration in mouse model of restraint stress

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 294, Issue 5, 2008, Pages

  Mazzon, Emanuela ^a   Cuzzocrea, Salvatore ^a,b  

^a IRCCS CENTRO NEUROLESI BONINO PULEJO   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

Author keywords

catenin; Apoptosis; Claudin 2; Tight junction; TNF deficient mice; Zonula occludens 1

Indexed keywords

BETA CATENIN; CLAUDIN 2; CLAUDIN 4; CLAUDIN 5; PROTEIN BAX; PROTEIN BCL 2; PROTEIN ZO1; TUMOR NECROSIS FACTOR ALPHA; MEMBRANE PROTEIN; OCCLUDIN; PHOSPHOPROTEIN; TUMOR NECROSIS FACTOR RECEPTOR 1; ZONULA OCCLUDENS 1 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLON MUCOSA; CONTROLLED STUDY; GENE DELETION; ILEUM DYSFUNCTION; ILEUM MUCOSA; IMMOBILIZATION STRESS; IMMUNOHISTOCHEMISTRY; INTESTINE MUCOSA PERMEABILITY; KNOCKOUT MOUSE; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TIGHT JUNCTION; ANIMAL; APOPTOSIS; C57BL MOUSE; CELL MEMBRANE PERMEABILITY; COLON; DEFECATION; EXERCISE; GENETICS; ILEUM; INTESTINE MUCOSA; MENTAL STRESS; METABOLISM; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY; STOMACH MUCOSA;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BETA CATENIN; CELL MEMBRANE PERMEABILITY; COLON; DEFECATION; GASTRIC MUCOSA; ILEUM; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHOPROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RESTRAINT, PHYSICAL; STRESS, PSYCHOLOGICAL; TIGHT JUNCTIONS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 45849127579     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00014.2008     Document Type: Article

References (65)

1. Abe Y, Watanabe Y, Kimura S. The role of tumor necrosis factor receptors in cell signaling and the significance of soluble form levels in the serum. Surg Today 24: 197-202, 1994.
2. Aggarwal BB. Tumour necrosis factors receptor associated signalling molecules and their role in activation of apoptosis, JNK and NF-kappaB. Ann Rheum Dis 59, Suppl 1: i6-i16, 2000.
3. Aloisi AM, Ceccarelli I, Lupo C. Behavioural and hormonal effects of restraint stress and formalin test in male and female rats. Brain Res Bull 47: 57-62, 1998.
4. Anderson JM, Van Itallie CM. Tight junctions and the molecular basis for regulation of paracellular permeability. Am J Physiol Gastrointest Liver Physiol 269: G467-G475, 1995.
5. Bruewer M, Luegering A, Kucharzik T, Parkos CA, Madara JL, Hopkins AM, Nusrat A. Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms. J Immunol 171: 6164-6172, 2003.
6. Clayburgh DR, Barrett TA, Tang Y, Meddings JB, Van Eldik LJ, Watterson DM, Clarke LL, Mrsny RJ, Turner JR. Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo. J Clin Invest 115: 2702-2715, 2005.
7. Clayburgh DR, Shen L, Turner JR. A porous defense: the leaky epithelial barrier in intestinal disease. Lab Invest 84: 282-291, 2004.
8. Coopersmith CM, Stromberg PE, Dunne WM, Davis CG, Amiot DM 2nd, Buchman TG, Karl IE, Hotchkiss RS. Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis. JAMA 287: 1716-1721, 2002.
9. Coyne CB, Vanhook MK, Gambling TM, Carson JL, Boucher RC, Johnson LG. Regulation of airway tight junctions by proinflammatory cytokines. Mol Biol Cell 13: 3218-3234, 2002.
10. Crisafulli C, Mazzon E, Muia C, Bella P, Esposito E, Meli R, Cuzzocrea S. Effects of combination of melatonin and dexamethasone on acute lung injury in a mice model of carrageenan-induced pleurisy. J Pineal Res 41: 228-237, 2006.
11. Das UN. Critical advances in septicemia and septic shock. Crit Care 4: 290-296, 2000.
12. Di Paola R, Mazzon E, Muia C, Crisafulli C, Terrana D, Greco S, Britti D, Santori D, Oteri G, Cordasco G, Cuzzocrea S. Effects of etanercept, a tumour necrosis factor-alpha antagonist, in an experimental model of periodontitis in rats. Br J Pharmacol 150: 286-297, 2007.
13. Esposito E, Mazzon E, Muia C, Meli R, Sessa E, Cuzzocrea S. Splanchnic ischemia and reperfusion injury is reduced by genetic or pharmacological inhibition of TNF-alpha. J Leukoc Biol 81: 1032-1043, 2007.
14. Fanning AS, Jameson BJ, Jesaitis LA, Anderson JM. The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. J Biol Chem 273: 29745-29753, 1998.
15. Farquhar MG, Palade GE. Junctional complexes in various epithelia. J Cell Biol 17: 375-412, 1963.
16. Fink MP, Delude RL. Epithelial barrier dysfunction: a unifying theme to explain the pathogenesis of multiple organ dysfunction at the cellular level. Crit Care Clin 21: 177-196, 2005.
17. Frode TS, Souza GE, Calixto JB. The modulatory role played by TNF-alpha and IL-1 beta in the inflammatory responses induced by carrageenan in the mouse model of pleurisy. Cytokine 13: 162-168, 2001.
18. Gonzalez-Mariscal L, Betanzos A, Avila-Flores A. MAGUK proteins: structure and role in the tight junction. Semin Cell Dev Biol 11: 315-324, 2000.
19. Gonzalez-Mariscal L, Betanzos A, Nava P, Jaramillo BE. Tight junction proteins. Prog Biophys Mol Biol 81: 1-44, 2003.
20. Grell M, Becke FM, Wajant H, Mannel DN, Scheurich P. TNF receptor type 2 mediates thymocyte proliferation independently of TNF receptor type 1. Eur J Immunol 28: 257-263, 1998.
21. Han X, Fink MP, Uchiyama T, Yang R, Delude RL. Increased iNOS activity is essential for hepatic epithelial tight junction dysfunction in endotoxemic mice. Am J Physiol Gastrointest Liver Physiol 286: G126-G136, 2004.
22. Han X, Fink MP, Uchiyama T, Yang R, Delude RL. Increased iNOS activity is essential for pulmonary epithelial tight junction dysfunction in endotoxemic mice. Am J Physiol Lung Cell Mol Physiol 286: L259-L267, 2004.
23. Han X, Fink MP, Yang R, Delude RL. Increased iNOS activity is essential for intestinal epithelial tight junction dysfunction in endotoxemic mice. Shock 21: 261-270, 2004.
24. Hanada S, Harada M, Koga H, Kawaguchi T, Taniguchi E, Kumashiro R, Ueno T, Ueno Y, Ishii M, Sakisaka S, Sata M. Tumor necrosis factor-alpha and interferon-gamma directly impair epithelial barrier function in cultured mouse cholangiocytes. Liver Int 23: 3-11, 2003.
25. Hsu H, Shu HB, Pan MG, Goeddel DV. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways. Cell 84: 299-308, 1996.
26. Hu WH, Johnson H, Shu HB. Tumor necrosis factor-related apoptosisinducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways. J Biol Chem 274: 30603-30610, 1999.
27. Idriss HT, Naismith JH. TNF alpha and the TNF receptor superfamily: structure-function relationship(s). Microsc Res Tech 50: 184-195, 2000.
28. Jacob C, Yang PC, Darmoul D, Amadesi S, Saito T, Cottrell GS, Coelho AM, Singh P, Grady EF, Perdue M, Bunnett NW. Mast cell tryptase controls paracellular permeability of the intestine. Role of protease-activated receptor 2 and beta-arrestins. J Biol Chem 280: 31936-31948, 2005.
29. Kiliaan AJ, Saunders PR, Bijlsma PB, Berin MC, Taminiau JA, Groot JA, Perdue MH. Stress stimulates transepithelial macromolecular uptake in rat jejunum. Am J Physiol Gastrointest Liver Physiol 275: G1037-G1044, 1998.
30. Kim KW, Choi SS, Woo RS, Suh HW. Development of antinociceptive tolerance and changes of opioid receptor ligand binding in central nervous system of the mouse forced to single and repeated swimming in the cold water. Brain Res Bull 61: 93-97, 2003.
31. Kondoh M, Yagi K. Progress in absorption enhancers based on tight junction. Expert Opin Drug Deliv 4: 275-286, 2007.
32. Lee NP, Yeung WS, Luk JM. Junction interaction in the seminiferous epithelium: regulatory roles of connexin-based gap junction. Front Biosci 12: 1552-1562, 2007.
33. Liu ZG, Hsu H, Goeddel DV, Karin M. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death. Cell 87: 565-576, 1996.
34. Luscinskas FW, Ma S, Nusrat A, Parkos CA, Shaw SK. Leukocyte transendothelial migration: a junctional affair. Semin Immunol 14: 105-113, 2002.
35. Ma TY, Iwamoto GK, Hoa NT, Akotia V, Pedram A, Boivin MA, Said HM. TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-B activation. Am J Physiol Gastrointest Liver Physiol 286: G367-G376, 2004.
36. Mazzon E, Cuzzocrea S. Thalidomide treatment reduces the alteration of paracellular barrier function in mice ileum during experimental colitis. Shock 25: 515-521, 2006.
37. Mazzon E, Sautebin L, Caputi AP, Cuzzocrea S. 5-Lipoxygenase modulates the alteration of paracellular barrier function in mice ileum during experimental colitis. Shock 25: 377-383, 2006.
38. Mazzon E, Sturniolo GC, Puzzolo D, Frisina N, Fries W. Effect of stress on the paracellular barrier in the rat ileum. Gut 51: 507-513, 2002.
39. McEwen BS. The neurobiology of stress: from serendipity to clinical relevance. Brain Res 886: 172-189, 2000.
40. McEwen BS. Plasticity of the hippocampus: adaptation to chronic stress and allostatic load. Ann NY Acad Sci 933: 265-277, 2001.
41. Mitic LL, Anderson JM. Molecular architecture of tight junctions. Annu Rev Physiol 60: 121-142, 1998.
42. Nukina H, Sudo N, Komaki G, Yu X, Mine K, Kubo C. The restraint stress-induced elevation in plasma interleukin-6 negatively regulates the plasma TNF-alpha level. Neuroimmunomodulation 5: 323-327, 1998.
43. Pereda J, Sabater L, Aparisi L, Escobar J, Sandoval J, Vina J, Lopez-Rodas G, Sastre J. Interaction between cytokines and oxidative stress in acute pancreatitis. Curr Med Chem 13: 2775-2787, 2006.
44. Poritz LS, Garver KI, Green C, Fitzpatrick L, Ruggiero F, Koltun WA. Loss of the tight junction protein ZO-1 in dextran sulfate sodium induced colitis. J Surg Res 140: 12-19, 2007.
45. Puthenedam M, Williams PH, Lakshmi BS, Balakrishnan A. Modulation of tight junction barrier function by outer membrane proteins of enteropathogenic Escherichia coli: role of F-actin and junctional adhesion molecule-1. Cell Biol Int 31: 836-844, 2007.
46. Rios-Barrera VA, Campos-Pena V, Aguilar-Leon D, Lascurain LR, Meraz-Rios MA, Moreno J, Figueroa-Granados V, Hernandez-Pando R. Macrophage and T lymphocyte apoptosis during experimental pulmonary tuberculosis: their relationship to mycobacterial virulence. Eur J Immunol 36: 345-353, 2006.
47. Salama NN, Eddington ND, Fasano A. Tight junction modulation and its relationship to drug delivery. Adv Drug Delivery Res 58: 15-28, 2006.
48. Saunders PR, Hanssen NP, Perdue MH. Cholinergic nerves mediate stress-induced intestinal transport abnormalities in Wistar-Kyoto rats. Am J Physiol Gastrointest Liver Physiol 273: G486-G490, 1997.
49. Saunders PR, Kosecka U, McKay DM, Perdue MH. Acute stressors stimulate ion secretion and increase epithelial permeability in rat intestine. Am J Physiol Gastrointest Liver Physiol 267: G794-G799, 1994.
50. Schneeberger EE, Lynch RD. Structure, function, and regulation of cellular tight junctions. Am J Physiol Lung Cell Mol Physiol 262: L647-L661, 1992.
51. Schneeberger EE, Lynch RD. The tight junction: a multifunctional complex. Am J Physiol Cell Physiol 286: C1213-C1228, 2004.
52. Shen HM, Pervaiz S. TNF receptor superfamily-induced cell death: redox-dependent execution. FASEB J 20: 1589-1598, 2006.
53. Soler AP, Marano CW, Bryans M, Miller RD, Garulacan LA, Mauldin SK, Stamato TD, Mullin JM. Activation of NF-kappaB is necessary for the restoration of the barrier function of an epithelium undergoing TNF-alpha-induced apoptosis. Eur J Cell Biol 78: 56-66, 1999.
54. Suh HW, Song DK, Huh SO, Kim YH. Involvement of dynorphin in immobilization stress-induced antinociception in the mouse. Eur Neuropsychopharmacol 10: 407-413, 2000.
55. Taylor CT, Dzus AL, Colgan SP. Autocrine regulation of epithelial permeability by hypoxia: role for polarized release of tumor necrosis factor alpha. Gastroenterology 114: 657-668, 1998.
56. Tsigos C, Chrousos GP. Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress. J Psychosom Res 53: 865-871, 2002.
57. Utech M, Bruwer M, Nusrat A. Tight junctions and cell-cell interactions. Methods Mol Biol 341: 185-195, 2006.
58. Utsunomiya I, Ito M, Oh-ishi S. Generation of inflammatory cytokines in zymosan-induced pleurisy in rats: TNF induces IL-6 and cytokine-induced neutrophil chemoattractant (CINC) in vivo. Cytokine 10: 956-963, 1998.
59. Villa P, Ghezzi P. Animal models of endotoxic shock. Methods Mol Med 98: 199-206, 2004.
60. Viswanathan VK, Hecht G. Innate immunity and the gut. Curr Opin Gastroenterol 16: 546-551, 2000.
61. Wang M, Li Q, Wang J, Li Y, Zhu W, Li N, Li J. Intestinal tight junction in allograft after small bowel transplantation. Transplant Proc 39: 289-291, 2007.
62. Warren JS, Ward PA, Johnson KJ. Tumor necrosis factor: a plurifunctional mediator of acute inflammation. Mod Pathol 1: 242-247, 1988.
63. Yang R, Harada T, Li J, Uchiyama T, Han Y, Englert JA, Fink MP. Bile modulates intestinal epithelial barrier function via an extracellular signal related kinase 1/2 dependent mechanism. Intensive Care Med 31: 709-717, 2005.
64. Yeaman C, Grindstaff KK, Nelson WJ. New perspectives on mechanisms involved in generating epithelial cell polarity. Physiol Rev 79: 73-98, 1999.
65. Zolotarevsky Y, Hecht G, Koutsouris A, Gonzalez DE, Quan C, Tom J, Mrsny RJ, Turner JR. A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease. Gastroenterology 123: 163-172, 2002.