Myelophil, a mixture of Astragali Radix and Salviae Radix extract, moderates toxic side effects of fluorouracil in mice

World Journal of Gastroenterology

Volumn 14, Issue 15, 2008, Pages 2323-2328

  Shin, Jang Woo ^a   Lee, Myong Min ^a   Son, Jin Young ^a   Lee, Nam Heon ^a   Cho, Chong Kwan ^a   Chung, Won Kyu ^b   Cho, Jung Hyo ^a   Son, Chang Gue ^a  

^a Daejeon University   (South Korea)

^b Konyang University   (South Korea)

Author keywords

Astragalus membranaceus; Chemotherapy; Immunosuppresion; Myelosuppression; Salvia miltiorrhizae

Indexed keywords

ASTRAGALUS MEMBRANACEUS EXTRACT; FLUOROURACIL; INTERLEUKIN 3; MYELOPHIL; SALVIA MILTIORRHIZA EXTRACT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CELL COUNT; BONE MARROW CELL; BONE MARROW SUPPRESSION; CELL DENSITY; COLONY FORMING UNIT E; COLONY FORMING UNIT GM; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; DRUG DOSE COMPARISON; DRUG EFFICACY; ERYTHROCYTE COUNT; FORCED SWIMMING TEST; GENE EXPRESSION; HISTOPATHOLOGY; LEUKOCYTE COUNT; MALE; MOUSE; NONHUMAN; REGULATORY MECHANISM; SPLEEN CELL; SURVIVAL RATE; SURVIVAL TIME; THROMBOCYTE COUNT;

EID: 45849125749     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.14.2323     Document Type: Article

References (32)

1. Carelle N, Piotto, E, Bellanger A, Germanaud J, Thuillier A, Khayat D. Changing patient perceptions of the side effects of cancer chemotherapy. Cancer 2002; 95: 155-163
2. Schuell B, Gruenberger T, Kornek GV, Dworan N, Depisch D, Lang F, Schneeweiss B, Scheithauer W. Side effects during chemotherapy predict tumour response in advanced colorectal cancer. Br J Cancer 2005; 93: 744-748
3. Hassett MJ, O'Malley AJ, Pakes JR, Newhouse JP, Earle CC. Frequency and cost of chemotherapy-related serious adverse effects in a population sample of women with breast cancer. J Natl Cancer Inst 2006; 98: 1108-1117
4. Friberg LE, Henningsson A, Maas H, Nguyen L, Karlsson MO. Model of chemotherapy-induced myelosuppression with parameter consistency across drugs. J Clin Oncol 2002; 20: 4713-4721
5. Senecal FM, Yee L, Gabrail N, Charu V, Tomita D, Rossi G, Schwartzberg L. Treatment of chemotherapy-induced anemia in breast cancer: results of a randomized controlled trial of darbepoetin alfa 200 microg every 2 weeks versus epoetin alfa 40,000 U weekly. Clin Breast Cancer 2005; 6: 446-454
6. Ludwig H, Strasser K. Symptomatology of anemia. Semin Oncol 2001; 28: 7-14
7. Mayers C, Panzarella T, Tannock IF. Analysis of the prognostic effects of inclusion in a clinical trial and of myelosuppression on survival after adjuvant chemotherapy for breast carcinoma. Cancer 2001; 91: 2246-2257
8. Steele TA. Chemotherapy-induced immunosuppression and reconstitution of immune function. Leuk Res 2002; 26: 411-414
9. Son CG, Han SH, Cho JH, Shin JW, Cho CH, Lee YW, Cho CK. Induction of hemopoiesis by saenghyuldan, a mixture of Ginseng radix, Paeoniae radix alba, and Hominis placenta extracts. Acta Pharmacol Sin 2003; 24: 120-126
10. Wilke HJ, Van Cutsem E. Current treatments and future perspectives in colorectal and gastric cancer. Ann Oncol 2003; 14 Suppl. 2: ii49-ii55
11. Louvet C, Andre T, Tigaud JM, Gamelin E, Douillard JY, Brunet R, Francois E, Jacob JH, Levoir D, Taamma A, Rougier P, Cvitkovic E, de Gramont A. Phase II study of oxaliplatin, fluorouracil, and folinic acid in locally advanced or metastatic gastric cancer patients. J Clin Oncol 2002; 20: 4543-4548
12. Cho WC, Leung KN. In vitro and in vivo immunomodulating and immunorestorative effects of Astragalus membranaceus. J Ethnopharmacol 2007; 113: 132-141
13. Sun WY, Wei W, Wu L, Gui SY, Wang H. Effects and mechanisms of extract from Paeonia lactiflora and Astragalus membranaceus on liver fibrosis induced by carbon tetrachloride in rats. J Ethnopharmacol 2007; 112: 514-523
14. Zhu XL, Zhu BD. Mechanisms by which Astragalus membranaceus injection regulates hematopoiesis in myelosuppressed mice. Phytother Res 2007; 21: 663-667
15. Tang MK, Ren DC, Zhang JT, Du GH. Effect of salvianolic acids from Radix Salviae miltiorrhizae on regional cerebral blood flow and platelet aggregation in rats. Phytomedicine 2002; 9: 405-409
16. Koo BS, Kwon TS, Kim CH. Salviae miltiorrhizae radix inhibits superoxide generation by activated rat microglias and mimics the action of amphetamine on in vitro rat striatal dopamine release. Neurochem Res 2004; 29: 1837-1845
17. Li S, Wan L. Experimental study on the preventive mechanism of salviae miltiorrhizae against atherosclerosis in rabbits models. J Huazhong Univ Sci Technolog Med Sci 2004; 24: 233-235
18. Kojima S, Takaba K, Kimoto N, Takeda T, Kakuni M, Mizutani M, Suzuki K, Sato H, Hara T. Protective effects of glutathione on 5-fluorouracil-induced myelosuppression in mice. Arch Toxicol 2003; 77: 285-290
19. Takano F, Tanaka T, Aoi J, Yahagi N, Fushiya S. Protective effect of (+)-catechin against 5-fluorouracil-induced myelosuppression in mice. Toxicology 2004; 201: 133-142
20. Vento S, Cainelli F. Infections in patients with cancer undergoing chemotherapy: aetiology, prevention, and treatment. Lancet Oncol 2003; 4: 595-604
21. Rolston KV. Challenges in the treatment of infections caused by gram-positive and gram-negative bacteria in patients with cancer and neutropenia. Clin Infect Dis 2005; 40 Suppl 4: S246-S252
22. Savino W, Smaniotto S, Dardenne M. Hematopoiesis. Adv Exp Med Biol 2005; 567: 167-185
23. Kaushansky K. Lineage-specific hematopoietic growth factors. N Engl J Med 2006; 354: 2034-2045
24. Mangi MH, Newland AC. Interleukin-3 in hematology and oncology: current state of knowledge and future directions. Cytokines Cell Mol Ther 1999; 5: 87-95
25. Leite-de-Moraes MC, Lisbonne M, Arnould A, Machavoine F, Herbelin A, Dy M, Schneider E. Ligand-activated natural killer T lymphocytes promptly produce IL-3 and GM-CSF in vivo: relevance to peripheral myeloid recruitment. Eur J Immunol 2002; 32: 1897-1904
26. Cella D. Factors influencing quality of life in cancer patients: anemia and fatigue. Semin Oncol 1998; 25: 43-46
27. Groopman JE, Itri LM. Chemotherapy-induced anemia in adults: incidence and treatment. J Natl Cancer Inst 1999; 91: 1616-1634
28. Biran H, Sulkes A, Biran S. 5-Fluorouracil, doxorubicin (adriamycin) and mitomycin-C (FAM) in advanced gastric cancer: observations on response, patient characteristics, myelosuppression and delivered dosage. Oncology 1989; 46: 83-87
29. Zhang M, Liu X, Li J, He L, Tripathy D. Chinese medicinal herbs to treat the side-effects of chemotherapy in breast cancer patients. Cochrane Database Syst Rev 2007, CDO04921
30. Liao HF, Chen YJ, Yang YC. A novel polysaccharide of black soybean promotes myelopoiesis and reconstitutes bone marrow after 5-flurouracil- and irradiation-induced myelosuppression. Life Sci 2005; 77: 400-413
31. Sugiyama K, Ueda H, Ichio Y. Protective effect of juzen-taiho-to against carboplatin-induced toxic side effects in mice. Biol Pharm Bull 1995; 18: 544-548
32. Molassiotis A, Fernadez-Ortega P, Pud D, Ozden G, Scott JA, Panteli V, Margulies A, Browall M, Magri M, Selvekerova S, Madsen E, Milovics L, Bruyns I, Gudmundsdottir G, Hummerston S, Ahmad AM, Platin N, Kearney N, Patiraki E. Use of complementary and alternative medicine in cancer patients: a European survey. Ann Oncol 2005; 16: 655-663