Induction of hemopoiesis by Saenghyuldab, a mixture of Ginseng Radix, Paeoniae Radix Alba, and Hominis Placenta extracts

Acta Pharmacologica Sinica

Volumn 24, Issue 2, 2003, Pages 120-126

  Son, Chang Gue ^a   Han, Seung Hyun ^b   Cho, Jung Hyo ^a   Shin, Jang Woo ^a   Cho, Chin Ho ^a   Lee, Yeon Weol ^a   Cho, Chong Kwan ^a  

^a Daejeon University   (South Korea)

^b International Vaccine Institute   (South Korea)

Author keywords

Hematopoiesis; Placenta Hominis; Radix Ginseng; Radix Paeoniae Alba; Saenghyuldan

Indexed keywords

CYCLOPHOSPHAMIDE; CYTOKINE; ERYTHROPOIETIN; GRANULOCYTE COLONY STIMULATING FACTOR; MESSENGER RNA; PAEONIA RADIX; PLANT EXTRACT; SAENGHYULDAN; STEM CELL FACTOR; THROMBOPOIETIN; UNCLASSIFIED DRUG; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MATERIA MEDICA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; BONE MARROW CELL; BONE MARROW DEPRESSION; BONE MARROW SUPPRESSION; CELL DENSITY; CELL SURVIVAL; CELL TYPE; CONTROLLED STUDY; DRUG EFFICACY; DRUG ISOLATION; ERYTHROCYTE COUNT; FEMALE; GINSENG; HEMATOPOIESIS; HISTOPATHOLOGY; LEUKOCYTE COUNT; MONOCYTE; MOUSE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CANCER TRANSPLANTATION; CHEMISTRY; DRUG COMBINATION; DRUG EFFECT; GENETICS; INSTITUTE FOR CANCER RESEARCH MOUSE; ISOLATION AND PURIFICATION; MEDICINAL PLANT; METABOLISM; PAEONIA; PATHOLOGY; SARCOMA 180;

ANIMALS; BONE MARROW CELLS; CYTOKINES; DRUG COMBINATIONS; ERYTHROPOIETIN; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEMATOPOIESIS; MATERIA MEDICA; MICE; MICE, INBRED BALB C; MICE, INBRED ICR; NEOPLASM TRANSPLANTATION; PAEONIA; PANAX; PLANT EXTRACTS; PLANTS, MEDICINAL; RNA, MESSENGER; SARCOMA 180; STEM CELL FACTOR; THROMBOPOIETIN;

EID: 0037308132     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Peckham M, Pinedo H, Veronesi U. Oxford textbook of oncology, v 4. New York: Oxford University Press Inc; 1995. p 445-53.
2. Boik J. Cancer & natural medicine. Minnesota: Oregon Medical Press; 1996. p 80-9.
3. Grossmann A, Lenox J, Ren HP, Humes JM, Forstrom JW, Kaushansky K, et al. Thrombopoietin accelerates platelet, red blood cell, and neutrophil recovery in myelosuppressed mice. Exp Hematol 1996; 24: 1238-46.
4. Morrison SJ, Wright DE, Weissman IL. Cyclophosphamide/ granulocyte colony-stimulating factor induce hematopoietic stem cells to proliferate prior to mobilization. Immunology 1996; 94: 1908-13.
5. Bernstein SH, Christiansen NP, Fay JP, Brown R, Herzig R, Frankel S, et al. Granulocyte-macrophage colony-stimulating factor (GM-CSF) priming of high-dose etoposide and cyclophosphamide: A pilot trial. Exp Hematol 1996; 24: 1363-8.
6. Chudgar UH, Rundus CH, Peterson VM. Recombinant human interleukin-1 receptor antagonist protects early myeloid progenitors in a murine model of cyclophosphamide-induced myelotoxicity. Am Soc Hematol 1995; 85: 2393-401.
7. Banu N, Wang JF, Deng B, Groopman JE, Avraham H. Modulation of magakaryocytopoiesis by thrombopoietin: The c-mpl ligand. Am Soc Hematol 1995; 86: 1331-8.
8. Zandstra PW, Conneally E, Petzer AL, Piret JM, Eaves CJ. Cytokine manipulation of primitive human hematopoietic cell self-renewal. Proc Natl Acad Sci USA 1997; 94: 4698-703.
9. Kaneko M, Kawakita T, Kumazawa Y, Takimoto H, Nomoto K, Yoshikawa T. Accelerated recovery from cyclophosphamide-induced leukopenia in mice administered a Japanese ethical herbal drug, Hochu-ekkii-to. Immunopharmacology 1999; 44: 223-31.
10. Oh DJ, Park MH, Park SS, Yoon JH, Cho HI. Effects of natural products on hemopoiesis in rats. Korean J Hematol 1996; 31: 225-34.
11. Jeong MK, Kim YK, Jang IM, Kim SY. An experimental study for the evaluation of hemopoietic effects of 9 medical plants used in herbal drugs. Korean J Hematol 1993; 28: 285-98.
12. Lee YW, Son CK, Cho CK. The effects of Saenghyuldan on the bone marrow failure. J Korean Oriental Med 2001; 22: 33-45.
13. Kalechman Y, Rushkin G, Nerubay J, Albeck M, Sredni B. Effect of the immunomodulator AS101 on chemotherapy-induced multilineage myelosuppression, thrombocytopenia, and anemia in mice. Exp Hematol 1995; 23: 1358-66.
14. Anthony D, Ahetton, Gerry J, Graham. Homing and mobilization in the stem cell niche. Trends Cell Biol 1999; 9: 233-8.
15. Whetton AD, Spooncer E. Role of cytokines and extracellular matrix in the regulation of hemopoietic stem cells. Curr Opinion Cell Biol 1998; 10: 721-6.
16. Roit I, Brostoff J, Male D. Immunology; v 5. London: Mosby International Ltd; 1998. p 155-69.
17. Stites DP, Terr AI, Parslow TG. Medical immunology. v 9. New Jersey: Simon & Schuster Company; 1997. p 146-67.
18. Alan DD. Hematopoietic growth factors and the regulation of differentiative decisions. Curr Opinion Cell Biol 1994; 6: 804-8.
19. Linnekin D. Early signaling pathways activated by c-Kit in hematopoietic cells. Int J Biochem Cell Biol 1999; 31: 1053-74.
20. Carow CE, Hangoc G, Cooper SH, Willaiams DE, Broxmeyer HE. Mast cell growth factor (c-kit ligand) supports the growth of human multipotential progenitor cells with a high replating potential. Blood 1991; 78: 2216-21.
21. Braddell RA, Bruno E, Cooper RJ, Brandt JE, Hoffman R. Effect of c-kit ligand on in vivo human megakaryocytopoiesis. Blood 1991; 78: 2854-9.
22. Heyworth CM, Whetton AD, Nicholls S, Zsebo KM, Dexter M. Stem cell factor directly stimulate the development of enriched granulocyte macrophage colony forming cells and promotes the effects of other colony stimulating factors. Blood 1992; 80: 2230-6.
23. Neelis KJ, Dubbelman YD, Qingliang L, Thomas GR, Eaton DL, Wagemaker G. Simultaneous administration of TPO and G-CSF after cytoreductive treatment of rhesus monkeys prevents thrombocytopenia, accelerates platelet and red cell reconstitution, alleviates neutropenia, and promotes the recovery of immature bone marrow cells. Exp Hematol 1997; 25:1084-93.