The impact of vehicle on the relative potency of skin-sensitizing chemicals in the local lymph node assay

Cutaneous and Ocular Toxicology

Volumn 27, Issue 2, 2008, Pages 67-75

  Jowsey, Ian R ^a,c   Clapp, Catherine J ^a   Safford, Bob ^a   Gibbons, Ben T ^b   Basketter, David A ^a  

^a UNILEVER RESEARCH   (United Kingdom)

^b UNIVERSITY OF SURREY   (United Kingdom)

^c Smith and Nephew   (United Kingdom)

Author keywords

LLNA; Sensitization assessment factor; Skin sensitizing potency; Vehicle effects

Indexed keywords

2 BUTANONE; ACETONE; DERMATOLOGICAL AGENT; DIMETHYL SULFOXIDE; DRUG VEHICLE; N,N DIMETHYLFORMAMIDE; OLIVE OIL; PROPYLENE GLYCOL;

ARTICLE; CELL PROLIFERATION; CONCENTRATION (PARAMETERS); DIAGNOSTIC TEST; DRUG DETERMINATION; DRUG EXPOSURE; DRUG POTENCY; EC3 VALUE; HUMAN; HUMAN CELL; HUMAN TISSUE; LOCAL LYMPH NODE ASSAY; LYMPH NODE BIOPSY; MULTIPLE CHEMICAL SENSITIVITY; PREDICTION; QUANTITATIVE ANALYSIS; REFERENCE VALUE; RISK ASSESSMENT; SENSITIZATION ASSESSMENT FACTOR; SKIN SENSITIZATION;

ALLERGENS; ANIMALS; CELL PROLIFERATION; DERMATITIS, ALLERGIC CONTACT; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; IMMUNIZATION; LOCAL LYMPH NODE ASSAY; LYMPH NODES; MICE; MICE, INBRED CBA; ORGANIC CHEMICALS; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; SOLVENTS; VEHICLES;

EID: 45849105158     PISSN: 15569527     EISSN: 15569535     Source Type: Journal    
DOI: 10.1080/15569520801904655     Document Type: Article

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