The effect of chronic doxorubicin treatment on mitogen-activated protein kinases and heat stress proteins in rat hearts

Physiological Research

Volumn 57, Issue SUPPL. 2, 2008, Pages

  Simoncikova P ^a   Ravingerova T ^a   Barancik M ^a  

^a INSTITUTE OF CHEMISTRY   (Slovakia)

Author keywords

Doxorubicin; Heart; Heat stress proteins; MAPK

Indexed keywords

EID: 45849094744     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. ARAI M, YOGUCHI A, TAKIZAWA T, YOKOYAMA T, KANDA T, KURABAYASHI M, NAGAI R: Mechanism of doxorubicin-induced inhibition of sarcoplasmic reticulum Ca(2+)-ATPase gene transcription. Circ Res 86: 8-14, 2000 .
2. BARANČÍK M, IVANOVÁ M, RAVINGEROVÁ T, BERNÁTOVÁ I: The role of protein kinases in responses to chronic social stress in rat hearts. Physiol Res 56: 4P, 2007
3. BRADFORD M: A rapid and sensitive method for the quantitation of microgram quanties of protein utilizing the principle of protein-dye-binding. Anal Biochem 72: 248-254, 1976.
4. DOU F, YUAN LD, ZHU JJ: Heat shock protein 90 indirectly regulates ERK activity by affecting Raf protein metabolism. Acta Biochim Bioph Sinica 37, 501-505, 2005.
5. FERRANS VJ: Overview of cardiac pathology in relation to anthracycline cardiotoxicity. Cancer Treat Rep 62: 955-961, 1978.
6. ICHIHARA S, YAMADA Y, KAWAI Y, OSAWA T, FURUHASHI K, DUAN Z, ICHIHARA G: Roles of oxidative stress and Akt signaling in doxorubicin cardiotoxicity. Biochem Bioph Res Commun 359: 27-33, 2007.
7. KANG JV, ZHOU ZX, WANG GW, BURIDI A, KLEIN JB: Suppression by metallothionein of doxorubicin-induced cardiomyocyte apoptosis through inhibition of p38 mitogen-activated protein kinases. J Biol Chem 275: 13690-13698, 2000.
8. KIM EK, PARK JD, SHIM SY, KIM HS, KIM BI, CHOI JH, KIM JE: Effect of chronic hypoxia on proliferation, apoptosis, and HSP70 expression in mouse bronchiolar epithelial cells. Physiol Res 55: 405-411, 2006.
9. KYRIAKIS JM, AVRUCH J. Sounding the alarm: protein kinase cascades activated by stress and inflammation. J Biol Chem 271: 24313-24316, 1996.
10. MAYER MP, BUKAU B: Hsp70 chaperone systems: diversity of cellular functions and mechanism of action. Biol Chem 379: 261-268, 1998.
11. METTLER FP, YOUNG DM, WARD JM: Adriamycin-induced cardiotoxicity (cardiomyopathy and congestive heart failure) in rats. Cancer Res 37: 2705- 2713, 1977.
12. OHTSUBOA T, KANOB E, UEDAC K, MATSUMOTOB H, SAITOA T, HAYASHIB S, HATASHITAB M, JINB Z, SAITOA H: Enhancement of heat-induced heat shock protein (hsp)72 accumulation by doxorubicin (Dox) in vitro. Canc Lett 159: 49-55, 2000.
13. SAWYER DB, ZUPPINGER C, MILLER TA, EPPENBERGER HM, SUTER (TM): Modulation of anthracycline-induced myofibrillar disarray in rat ventricular myocytes by neuregulin-1beta and anti-erbB2: potential mechanism for trastuzumab-induced cardiotoxicity. Circulation 105:1551-1554, 2002.
14. SHAN YX, LIU TJ, SU HF SAMSAMSHARIAT A, MESTRIL R, WANG PH: Hsp10 and Hsp60 modulate Bcl-2 family and mitochondria apoptosis signaling induced by doxorubicin in cardiac muscle cells. J Mol Cell Cardiol 35: 1135-1143, 2003.
15. SINGAL PK, DEALLY CMR, WEINBERG LE: Subcellular effects of adriamycin in the heart: A concise review. J Mol Cell Cardiol 19: 817-828, 1987.
16. SINGAL PK, LI T, KUMAR D, DANELISEN I, ILISKOVIC N.: Adramycin-induced heart failure: mechanism and modulation. Mol Cell Biochem 207: 77-86, 2000.
17. STRNISKOVÁ M, BARANČÍK M, NECKÁŘ J, RAVINGEROVÂ T: Mitogen-activated protein kinases in the acute diabetic myocardium. Mol Cell Biochem 249: 59-65, 2003.
18. SUGDEN PH, BOGOYEVITCH MA: Intracellular signalling through protein kinases in the heart. Cardiovasc Res 30: 478-492, 1995.
19. THORNALLEY PJ, DODD NJ: Free radical production from normal and adriamycin-treated rat cardiac sarcosomes. Biochem Pharmacol 34: 669-674, 1985.
20. WANG X, MARTINDALE JL, LIU Y, HOLBROOK NJ: The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival. Biochem J 333: 291-300, 1998.
21. WANG S, KOTAMRAJU S, KONOREV E, KALIVENDI S, JOSEPH J, KALYANARAMAN B: Activation of nuclear factor-κB during doxorubicin-induced apoptosis in endothelial cells and myocytes is pro-apoptotic: the role of hydrogen peroxide. Biochem J 367: 729-740, 2002.
22. 2- and p53-dependent pathways. J Biol Chem 279: 25535-25543, 2004.
23. WU W, LEE WL, WU YY, CHEN D, LIU TJ, JANG A, SHARMA PM, WANG PH: Expression of constitutively active phosphatidylinositol 3-kinase inhibits activation of caspase 3 and apoptosis of cardiac muscle cells. J Biol Chem 275: 40113-40119, 2000.