-
1
-
-
0034443374
-
PTCH gene mutations in odontogenic keratocysts
-
Barreto D.C., Gomez R.S., Bale A.E., Boson W.L., and De Marco L. PTCH gene mutations in odontogenic keratocysts. J. Dent. Res. 79 (2000) 1418-1422
-
(2000)
J. Dent. Res.
, vol.79
, pp. 1418-1422
-
-
Barreto, D.C.1
Gomez, R.S.2
Bale, A.E.3
Boson, W.L.4
De Marco, L.5
-
2
-
-
0037200078
-
Medulloblastoma growth inhibition by hedgehog pathway blockade
-
Berman D.M., Karhadkar S.S., Hallahan A.R., Pritchard J.I., Eberhart C.G., Watkins D.N., Chen J.K., Cooper M.K., Taipale J., Olson J.M., and Beachy P.A. Medulloblastoma growth inhibition by hedgehog pathway blockade. Science 297 (2002) 1559-1561
-
(2002)
Science
, vol.297
, pp. 1559-1561
-
-
Berman, D.M.1
Karhadkar, S.S.2
Hallahan, A.R.3
Pritchard, J.I.4
Eberhart, C.G.5
Watkins, D.N.6
Chen, J.K.7
Cooper, M.K.8
Taipale, J.9
Olson, J.M.10
Beachy, P.A.11
-
3
-
-
0242268525
-
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
-
Berman D.M., Karhadkar S.S., Maitra A., Montes De Oca R., Gerstenblith M.R., Briggs K., Parker A.R., Shimada Y., Eshleman J.R., Watkins D.N., and Beachy P.A. Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature 425 (2003) 846-851
-
(2003)
Nature
, vol.425
, pp. 846-851
-
-
Berman, D.M.1
Karhadkar, S.S.2
Maitra, A.3
Montes De Oca, R.4
Gerstenblith, M.R.5
Briggs, K.6
Parker, A.R.7
Shimada, Y.8
Eshleman, J.R.9
Watkins, D.N.10
Beachy, P.A.11
-
4
-
-
0036724944
-
Analysis of the PTCH coding region in human rhabdomyosarcoma
-
Calzada-Wack J., Schnitzbauer U., Walch A., Wurster K.H., Kappler R., Nathrath M., and Hahn H. Analysis of the PTCH coding region in human rhabdomyosarcoma. Hum. Mutat. 20 (2002) 233-234
-
(2002)
Hum. Mutat.
, vol.20
, pp. 233-234
-
-
Calzada-Wack, J.1
Schnitzbauer, U.2
Walch, A.3
Wurster, K.H.4
Kappler, R.5
Nathrath, M.6
Hahn, H.7
-
5
-
-
40049101451
-
Gli-1 siRNA induced apoptosis in Huh7 cells
-
Chen X.L., Cao L.Q., She M.R., Wang Q., Huang X.H., and Fu X.H. Gli-1 siRNA induced apoptosis in Huh7 cells. World J. Gastroenterol. 14 (2008) 582-589
-
(2008)
World J. Gastroenterol.
, vol.14
, pp. 582-589
-
-
Chen, X.L.1
Cao, L.Q.2
She, M.R.3
Wang, Q.4
Huang, X.H.5
Fu, X.H.6
-
6
-
-
0142153787
-
The hedgehog signaling network
-
Cohen Jr. M.M. The hedgehog signaling network. Am. J. Med. Genet. A 123 (2003) 5-28
-
(2003)
Am. J. Med. Genet. A
, vol.123
, pp. 5-28
-
-
Cohen Jr., M.M.1
-
7
-
-
20644431776
-
Sonic hedgehog signaling in basal cell carcinomas
-
Daya-Grosjean L., and Couve-Privat S. Sonic hedgehog signaling in basal cell carcinomas. Cancer Lett. 225 (2005) 181-192
-
(2005)
Cancer Lett.
, vol.225
, pp. 181-192
-
-
Daya-Grosjean, L.1
Couve-Privat, S.2
-
8
-
-
0034682719
-
Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened
-
Denef N., Neubuser D., Perez L., and Cohen S.M. Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened. Cell 102 (2000) 521-531
-
(2000)
Cell
, vol.102
, pp. 521-531
-
-
Denef, N.1
Neubuser, D.2
Perez, L.3
Cohen, S.M.4
-
9
-
-
33947357165
-
Overexpression of hedgehog signaling molecules and its involvement in the proliferation of endometrial carcinoma cells
-
Feng Y.Z., Shiozawa T., Miyamoto T., Kashima H., Kurai M., Suzuki A., Ying-Song J., and Konishi I. Overexpression of hedgehog signaling molecules and its involvement in the proliferation of endometrial carcinoma cells. Clin. Cancer Res. 13 (2007) 1389-1398
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 1389-1398
-
-
Feng, Y.Z.1
Shiozawa, T.2
Miyamoto, T.3
Kashima, H.4
Kurai, M.5
Suzuki, A.6
Ying-Song, J.7
Konishi, I.8
-
10
-
-
16044363842
-
The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas
-
Gailani M.R., Stahle-Backdahl M., Leffell D.J., Glynn M., Zaphiropoulos P.G., Pressman C., Unden A.B., Dean M., Brash D.E., Bale A.E., and Toftgard R. The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas. Nat. Genet. 14 (1996) 78-81
-
(1996)
Nat. Genet.
, vol.14
, pp. 78-81
-
-
Gailani, M.R.1
Stahle-Backdahl, M.2
Leffell, D.J.3
Glynn, M.4
Zaphiropoulos, P.G.5
Pressman, C.6
Unden, A.B.7
Dean, M.8
Brash, D.E.9
Bale, A.E.10
Toftgard, R.11
-
11
-
-
15844386165
-
Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome
-
Hahn H., Wicking C., Zaphiropoulous P.G., Gailani M.R., Shanley S., Chidambaram A., Vorechovsky I., Holmberg E., Unden A.B., Gillies S., Negus K., Smyth I., Pressman C., Leffell D.J., Gerrard B., Goldstein A.M., Dean M., Toftgard R., Chenevix-Trench G., Wainwright B., and Bale A.E. Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 85 (1996) 841-851
-
(1996)
Cell
, vol.85
, pp. 841-851
-
-
Hahn, H.1
Wicking, C.2
Zaphiropoulous, P.G.3
Gailani, M.R.4
Shanley, S.5
Chidambaram, A.6
Vorechovsky, I.7
Holmberg, E.8
Unden, A.B.9
Gillies, S.10
Negus, K.11
Smyth, I.12
Pressman, C.13
Leffell, D.J.14
Gerrard, B.15
Goldstein, A.M.16
Dean, M.17
Toftgard, R.18
Chenevix-Trench, G.19
Wainwright, B.20
Bale, A.E.21
more..
-
12
-
-
0032241173
-
Gorlin syndrome: identification of 4 novel germ-line mutations of the human patched (PTCH) gene. Mutations in brief no. 137
-
Hasenpusch-Theil K., Bataille V., Laehdetie J., Obermayr F., Sampson J.R., and Frischauf A.M. Gorlin syndrome: identification of 4 novel germ-line mutations of the human patched (PTCH) gene. Mutations in brief no. 137. Online Hum. Mutat. 11 (1998) 480
-
(1998)
Online Hum. Mutat.
, vol.11
, pp. 480
-
-
Hasenpusch-Theil, K.1
Bataille, V.2
Laehdetie, J.3
Obermayr, F.4
Sampson, J.R.5
Frischauf, A.M.6
-
13
-
-
33745634379
-
Activation of the hedgehog pathway in human hepatocellular carcinomas
-
Huang S., He J., Zhang X., Bian Y., Yang L., Xie G., Zhang K., Tang W., Stelter A.A., Wang Q., Zhang H., and Xie J. Activation of the hedgehog pathway in human hepatocellular carcinomas. Carcinogenesis 27 (2006) 1334-1340
-
(2006)
Carcinogenesis
, vol.27
, pp. 1334-1340
-
-
Huang, S.1
He, J.2
Zhang, X.3
Bian, Y.4
Yang, L.5
Xie, G.6
Zhang, K.7
Tang, W.8
Stelter, A.A.9
Wang, Q.10
Zhang, H.11
Xie, J.12
-
14
-
-
15844381336
-
Human homolog of patched, a candidate gene for the basal cell nevus syndrome
-
Johnson R.L., Rothman A.L., Xie J., Goodrich L.V., Bare J.W., Bonifas J.M., Quinn A.G., Myers R.M., Cox D.R., Epstein Jr. E.H., and Scott M.P. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 272 (1996) 1668-1671
-
(1996)
Science
, vol.272
, pp. 1668-1671
-
-
Johnson, R.L.1
Rothman, A.L.2
Xie, J.3
Goodrich, L.V.4
Bare, J.W.5
Bonifas, J.M.6
Quinn, A.G.7
Myers, R.M.8
Cox, D.R.9
Epstein Jr., E.H.10
Scott, M.P.11
-
15
-
-
0033590605
-
A frequent activated smoothened mutation in sporadic basal cell carcinomas
-
Lam C.W., Xie J., To K.F., Ng H.K., Lee K.C., Yuen N.W., Lim P.L., Chan L.Y., Tong S.F., and McCormick F. A frequent activated smoothened mutation in sporadic basal cell carcinomas. Oncogene 18 (1999) 833-836
-
(1999)
Oncogene
, vol.18
, pp. 833-836
-
-
Lam, C.W.1
Xie, J.2
To, K.F.3
Ng, H.K.4
Lee, K.C.5
Yuen, N.W.6
Lim, P.L.7
Chan, L.Y.8
Tong, S.F.9
McCormick, F.10
-
16
-
-
4444327331
-
Next stop, the twilight zone: hedgehog network regulation of mammary gland development
-
Lewis M.T., and Veltmaat J.M. Next stop, the twilight zone: hedgehog network regulation of mammary gland development. J. Mammary Gland Biol. Neoplasia 9 (2004) 165-181
-
(2004)
J. Mammary Gland Biol. Neoplasia
, vol.9
, pp. 165-181
-
-
Lewis, M.T.1
Veltmaat, J.M.2
-
18
-
-
0031881427
-
Mutations in the human homologue of the Drosophila patched gene in esophageal squamous cell carcinoma
-
Maesawa C., Tamura G., Iwaya T., Ogasawara S., Ishida K., Sato N., Nishizuka S., Suzuki Y., Ikeda K., Aoki K., Saito K., and Satodate R. Mutations in the human homologue of the Drosophila patched gene in esophageal squamous cell carcinoma. Genes, Chromosomes Cancer 21 (1998) 276-279
-
(1998)
Genes, Chromosomes Cancer
, vol.21
, pp. 276-279
-
-
Maesawa, C.1
Tamura, G.2
Iwaya, T.3
Ogasawara, S.4
Ishida, K.5
Sato, N.6
Nishizuka, S.7
Suzuki, Y.8
Ikeda, K.9
Aoki, K.10
Saito, K.11
Satodate, R.12
-
19
-
-
0029948270
-
Biochemical evidence that patched is the Hedgehog receptor
-
Marigo V., Davey R.A., Zuo Y., Cunningham J.M., and Tabin C.J. Biochemical evidence that patched is the Hedgehog receptor. Nature 384 (1996) 176-179
-
(1996)
Nature
, vol.384
, pp. 176-179
-
-
Marigo, V.1
Davey, R.A.2
Zuo, Y.3
Cunningham, J.M.4
Tabin, C.J.5
-
21
-
-
0032480249
-
PTCH gene mutations in invasive transitional cell carcinoma of the bladder
-
McGarvey T.W., Maruta Y., Tomaszewski J.E., Linnenbach A.J., and Malkowicz S.B. PTCH gene mutations in invasive transitional cell carcinoma of the bladder. Oncogene 17 (1998) 1167-1172
-
(1998)
Oncogene
, vol.17
, pp. 1167-1172
-
-
McGarvey, T.W.1
Maruta, Y.2
Tomaszewski, J.E.3
Linnenbach, A.J.4
Malkowicz, S.B.5
-
22
-
-
0035050910
-
PTCH mutations in squamous cell carcinoma of the skin
-
Ping X.L., Ratner D., Zhang H., Wu X.L., Zhang M.J., Chen F.F., Silvers D.N., Peacocke M., and Tsou H.C. PTCH mutations in squamous cell carcinoma of the skin. J. Invest. Dermatol. 116 (2001) 614-616
-
(2001)
J. Invest. Dermatol.
, vol.116
, pp. 614-616
-
-
Ping, X.L.1
Ratner, D.2
Zhang, H.3
Wu, X.L.4
Zhang, M.J.5
Chen, F.F.6
Silvers, D.N.7
Peacocke, M.8
Tsou, H.C.9
-
23
-
-
0032080853
-
Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system
-
Reifenberger J., Wolter M., Weber R.G., Megahed M., Ruzicka T., Lichter P., and Reifenberger G. Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. Cancer Res. 58 (1998) 1798-1803
-
(1998)
Cancer Res.
, vol.58
, pp. 1798-1803
-
-
Reifenberger, J.1
Wolter, M.2
Weber, R.G.3
Megahed, M.4
Ruzicka, T.5
Lichter, P.6
Reifenberger, G.7
-
24
-
-
33645371509
-
Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis
-
Sicklick J.K., Li Y.X., Jayaraman A., Kannangai R., Qi Y., Vivekanandan P., Ludlow J.W., Owzar K., Chen W., Torbenson M.S., and Diehl A.M. Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis. Carcinogenesis 27 (2006) 748-757
-
(2006)
Carcinogenesis
, vol.27
, pp. 748-757
-
-
Sicklick, J.K.1
Li, Y.X.2
Jayaraman, A.3
Kannangai, R.4
Qi, Y.5
Vivekanandan, P.6
Ludlow, J.W.7
Owzar, K.8
Chen, W.9
Torbenson, M.S.10
Diehl, A.M.11
-
25
-
-
0011102935
-
The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
-
Stone D.M., Hynes M., Armanini M., Swanson T.A., Gu Q., Johnson R.L., Scott M.P., Pennica D., Goddard A., Phillips H., Noll M., Hooper J.E., de Sauvage F., and Rosenthal A. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog. Nature 384 (1996) 129-134
-
(1996)
Nature
, vol.384
, pp. 129-134
-
-
Stone, D.M.1
Hynes, M.2
Armanini, M.3
Swanson, T.A.4
Gu, Q.5
Johnson, R.L.6
Scott, M.P.7
Pennica, D.8
Goddard, A.9
Phillips, H.10
Noll, M.11
Hooper, J.E.12
de Sauvage, F.13
Rosenthal, A.14
-
26
-
-
0037158748
-
Patched acts catalytically to suppress the activity of Smoothened
-
Taipale J., Cooper M.K., Maiti T., and Beachy P.A. Patched acts catalytically to suppress the activity of Smoothened. Nature 418 (2002) 892-897
-
(2002)
Nature
, vol.418
, pp. 892-897
-
-
Taipale, J.1
Cooper, M.K.2
Maiti, T.3
Beachy, P.A.4
-
27
-
-
0033711384
-
Hedgehog signalling in cancer
-
Toftgard R. Hedgehog signalling in cancer. Cell. Mol. Life Sci. 57 (2000) 1720-1731
-
(2000)
Cell. Mol. Life Sci.
, vol.57
, pp. 1720-1731
-
-
Toftgard, R.1
-
28
-
-
0345517109
-
The patched/hedgehog/smoothened signalling pathway in human breast cancer: no evidence for H133Y SHH, PTCH and SMO mutations
-
Vorechovsky I., Benediktsson K.P., and Toftgard R. The patched/hedgehog/smoothened signalling pathway in human breast cancer: no evidence for H133Y SHH, PTCH and SMO mutations. Eur. J. Cancer 35 (1999) 711-713
-
(1999)
Eur. J. Cancer
, vol.35
, pp. 711-713
-
-
Vorechovsky, I.1
Benediktsson, K.P.2
Toftgard, R.3
-
29
-
-
0242669237
-
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
-
Watkins D.N., Berman D.M., Burkholder S.G., Wang B., Beachy P.A., and Baylin S.B. Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer. Nature 422 (2003) 313-317
-
(2003)
Nature
, vol.422
, pp. 313-317
-
-
Watkins, D.N.1
Berman, D.M.2
Burkholder, S.G.3
Wang, B.4
Beachy, P.A.5
Baylin, S.B.6
-
30
-
-
15644373337
-
Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors
-
Xie J., Johnson R.L., Zhang X., Bare J.W., Waldman F.M., Cogen P.H., Menon A.G., Warren R.S., Chen L.C., Scott M.P., and Epstein Jr. E.H. Mutations of the PATCHED gene in several types of sporadic extracutaneous tumors. Cancer Res. 57 (1997) 2369-2372
-
(1997)
Cancer Res.
, vol.57
, pp. 2369-2372
-
-
Xie, J.1
Johnson, R.L.2
Zhang, X.3
Bare, J.W.4
Waldman, F.M.5
Cogen, P.H.6
Menon, A.G.7
Warren, R.S.8
Chen, L.C.9
Scott, M.P.10
Epstein Jr., E.H.11
-
31
-
-
0031913524
-
Activating Smoothened mutations in sporadic basal-cell carcinoma
-
Xie J., Murone M., Luoh S.M., Ryan A., Gu Q., Zhang C., Bonifas J.M., Lam C.W., Hynes M., Goddard A., Rosenthal A., Epstein Jr. E.H., and de Sauvage F.J. Activating Smoothened mutations in sporadic basal-cell carcinoma. Nature 391 (1998) 90-92
-
(1998)
Nature
, vol.391
, pp. 90-92
-
-
Xie, J.1
Murone, M.2
Luoh, S.M.3
Ryan, A.4
Gu, Q.5
Zhang, C.6
Bonifas, J.M.7
Lam, C.W.8
Hynes, M.9
Goddard, A.10
Rosenthal, A.11
Epstein Jr., E.H.12
de Sauvage, F.J.13
|