Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S- transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in tuberculosis patients

Journal of Toxicological Sciences

Volumn 33, Issue 2, 2008, Pages 187-195

  Fukino, Katsumi ^a,b   Sasaki, Yuka ^c   Hirai, Shigekazu ^a   Nakamura, Takayuki ^a   Hashimoto, Masayo ^a   Yamagishi, Fumio ^c   Ueno, Koichi ^a  

^a CHIBA UNIVERSITY   (Japan)

^b CHIBA INSTITUTE OF SCIENCE   (Japan)

^c SAKURA NATIONAL HOSPITAL   (Japan)

Author keywords

CYP2E1; Genotype; Glutathione S transferase; Hydrazine; Isoniazid; N acetyltransferase 2

Indexed keywords

ARYLAMINE ACETYLTRANSFERASE; CYTOCHROME P450 2E1; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE T1; HYDRAZINE; ISONIAZID; RIFAMPICIN;

ARTICLE; CELL MUTANT; DNA POLYMORPHISM; DRUG ACCUMULATION; DRUG ACETYLATION; DRUG BLOOD LEVEL; DRUG HYDROLYSIS; GENETIC RISK; GENOTYPE; HOSPITAL PATIENT; HOSPITALIZATION; HUMAN; HUMAN CELL; LIVER DISEASE; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; RISK FACTOR;

EID: 45749141585     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.33.187     Document Type: Article

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