A dicarboxylate/4-hydroxybutyrate autotrophic carbon assimilation cycle in the hyperthermophilic Archaeum Ignicoccus hospitalis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 22, 2008, Pages 7851-7856

  Huber, Harald ^a   Gallenberger, Martin ^a   Jahn, Ulrike ^a   Eylert, Eva ^b   Berg, Ivan A ^c   Kockelkorn, Daniel ^c   Eisenreich, Wolfgang ^b   Fuchs, Georg ^c  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

4 hydroxybutyryl CoA dehydratase; Acetyl CoA; CO2 fixation pathway

Indexed keywords

4 HYDROXYBUTYRIC ACID; ACETYL COENZYME A; BUTYRYL COENZYME A DEHYDROGENASE; CARBON 13; CARBON 14; CARBON DIOXIDE; DICARBOXYLIC ACID; OXALOACETIC ACID; OXOGLUTARATE DEHYDROGENASE; PHOSPHOENOLPYRUVATE CARBOXYLASE; PYRUVATE SYNTHASE; SUCCINYL COENZYME A SYNTHETASE; THIOESTER; 4-HYDROXYBUTYRIC ACID; AMINO ACID; CARBON; HYDROXYBUTYRIC ACID; PROTEIN; PYRUVIC ACID; SUCCINIC ACID;

ANAEROBIC METABOLISM; ARTICLE; AUTOTROPHY; CARBON FIXATION; CITRIC ACID CYCLE; ENZYME ACTIVITY; FATTY ACID OXIDATION; HYPERTHERMOPHILIC ARCHAEON; IGNICOCCUS HOSPITALIS; NONHUMAN; PRIORITY JOURNAL; BIOSYNTHESIS; DESULFUROCOCCACEAE; METABOLISM;

IGNICOCCUS; NANOARCHAEUM EQUITANS;

ACETYL COENZYME A; AMINO ACIDS; CARBON DIOXIDE; CARBON ISOTOPES; DESULFUROCOCCACEAE; DICARBOXYLIC ACIDS; HYDROXYBUTYRATES; PROTEINS; PYRUVIC ACID; SUCCINIC ACID;

EID: 45549103517     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0801043105     Document Type: Article

References (33)

1. Paper W, et al. (2007) Ignicoccus hospitalis sp. nov., the host of "Nanoarchaeum equitans." Int J Syst Evol Microbiol 57:803-808.
2. Rachel R, Wyschkony I, Riehl S, Huber H (2002) The ultrastructure of Ignicoccus: Evidence for a novel outer membrane and for intracellular vesicle budding in an archaeon. Archaea 1:9 -18.
3. Huber H, et al. (2002) A new phylum of Archaea represented by a nanosized hyperthermophilic symbiont. Nature 417:63-67.
4. 2 fixation pathway of the archaeon Ignicoccus hospitalis: Comprehensive analysis of the central carbon metabolism. J Bacteriol 189:4108-4119.
5. 2 fixation pathways in archaea (Crenarchaeota). Arch Microbiol 179:160-173.
6. Martins BM, Dobbek H, Cinkaya I, Buckel W, Messerschmidt A (2004) Crystal structure of 4-hydroxybutyryl-CoA dehydratase: radical catalysis involving a [4Fe-4S] cluster and flavin. Proc Natl Acad Sci USA 101:15645-15649.
7. Buckel W, Golding BT (2006) Radical enzymes in anaerobes. Annu Rev Microbiol 60:27-49.
8. Gerhardt A, Cinkaya I, Linder D, Huisman G, Buckel W (2000) Fermentation of 4-aminobutyrate by Clostridium aminobutyricum: Cloning of two genes involved in the formation and dehydration of 4-hydroxybutyryl-CoA. Arch Microbiol 174:189-199.
9. Berg IA, Kockelkorn D, Buckel W, Fuchs G (2007) A 3-hydroxypropionate/4- hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea. Science 318:1782-1786.
10. Shemin D (1989) An illustration of the use of isotopes: The biosynthesis of porphyrins. BioEssays 10:30-35.
11. Thauer RK (2007) Microbiology. A fifth pathway of carbon fixation. Science 318:1732-1733.
12. Li F, Hagemeier CH, Seedorf H, Gottschalk G, Thauer RK (2007) Re-citrate synthase from Clostridium kluyveri is phylogenetically related to homocitrate synthase and isopropylmalate synthase rather than to Si-citrate synthase. J Bacteriol 189:4299-4304.
13. Hedderich R (2004) Energy-converting [NiFe] hydrogenases from archaea and extremophiles: Ancestors of complex I. J Bionenerg Biomembr 36:65-75.
14. 2 fixation pathway in the phototrophic bacterium Chloroflexus aurantiacus, the 3-hydroxypropionate cycle. Eur J Biochem 215:633-643.
15. 2 fixation by Chloroflexus aurantiacus: study of glyoxylate formation and assimilation via the 3-hydroxypropionate cycle. J Bacteriol 183:4305-4316.
16. Alber B, et al. (2006) Malonyl-coenzyme A reductase in the modified 3-hydroxypropionate cycle for autotrophic carbon fixation in archaeal Metallosphaera and Sulfolobus spp. J Bacteriol 188:8551-8559.
17. Buchanan BB, Arnon DI (1990) A reverse KREBS cycle in photosynthesis: Consensus at last. Photosynth Res 24:47-53.
18. 2 fixation pathways in the sulfur-reducing Archaebacterium Thermoproteus neutrophilus and in the phototrophic Eubacterium Chloroflexus aurantiacus. Eur J Biochem 205:853-866.
19. Beh M, Strauss G, Huber R, Stetter KO, Fuchs G (1993) Enzymes of the reductive citric acid cycle in the autotrophic eubacterium Aquifex pyrophilus and in the archaebacterium Thermoproteus neutrophilus. Arch Microbiol 160:306-311.
20. 2 fixation in Thermoproteus neutrophilus. Eur J Biochem 184:151-156.
21. 13C-NMR study of acetate assimilation in Thermoproteus neutrophilus. Eur J Biochem 186:695-700.
22. Hu Y, Holden JF (2006) Citric acid cycle in the hyperthermophilic archaeon Pyrobaculum islandicum grown autotrophically, heterotrophically, and mixotrophically with acetate. J Bacteriol 188:4350-4355.
23. Wächtershäuser G (2006) From volcanic origins of chemoautotrophic life to Bacteria, Archaea and Eukarya. Philos Trans R Soc London Ser B 361:1787-1808.
24. Brochier C, Forterre P, Gribaldo S (2005) An emerging phylogenetic core of Archaea: Phylogenies of transcription and translation machineries converge following addition of new genome sequences. BMC Evol Biol 5:36.
25. Huber H, et al. (2000) Ignicoccus gen. nov., a novel genus of hyperthermophilic, chemolithoautotrophic Archaea, represented by two new species, Ignicoccus islandicus sp nov and Ignicoccus pacificus sp nov. Int J Syst Evol Microbiol 50:2093-2100.
26. Simon EJ, Shemin D (1953) The preparation of S-succinyl-coenzyme A. J Am Chem Soc 75:2520.
27. Stadtman ER (1957) Preparation and assay of acyl coenzyme A and other thiol esters; use of hydroxylamine. Meth Enzymol 3:931-941.
28. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
29. Erb TJ, et al. (2007) Synthesis of C5-dicarboxylic acids from C2-units involving crotonyl-CoA carboxylase/reductase: The ethylmalonyl-CoA pathway. Proc Natl Acad Sci USA 104:10631-10636.
30. Eisenreich W, Schwarzkopf B, Bacher A (1991) Biosynthesis of nucleotides, flavins, and deazaflavins in Methanobacterium thermoautotrophicum. J Biol Chem 266:9622-9631.
31. 2 as a universal metabolic tracer in isotopologue perturbation experiments. Phytochemistry 68:2273-2289.
32. Benson DA, Karsch-Mizrachi I, Lipman DJ, Ostell J, Wheeler DL (2006) GenBank. Nucleic Acids Res 34:D16-D20.
33. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ (1990) Basic local alignment search tool. J Mol Biol 215:403-410.