Crystal structure of 4-hydroxybutyryl-CoA dehydratase: Radical catalysis involving a [4Fe-4S] cluster and flavin

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 44, 2004, Pages 15645-15649

  Martins, Berta M ^a,b   Dobbek, Holger ^b   Çinkaya, Irfan ^c,d   Buckel, Wolfgang ^c   Messerschmidt, Albrecht ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b UNIVERSITY OF BAYREUTH   (Germany)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d Chiron Vaccines   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYBUTYRYL COA DEHYDRATASE; CYSTEINE; HISTIDINE; HYDROLYASE; IRON COMPLEX; SULFUR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CLOSTRIDIUM; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; ENZYME SUBUNIT; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

CATALYSIS; CATALYTIC DOMAIN; CLOSTRIDIUM; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; EVOLUTION, MOLECULAR; FLAVIN-ADENINE DINUCLEOTIDE; FREE RADICALS; HYDRO-LYASES; IRON; MODELS, MOLECULAR; PROTEIN STRUCTURE, QUATERNARY; SULFUR;

BACTERIA (MICROORGANISMS); CLOSTRIDIUM; CLOSTRIDIUM AMINOBUTYRICUM;

EID: 8144230590     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0403952101     Document Type: Article

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