Synthesis of novel pyrrolo[3,4-d]pyrazole-dicarboxylic acids and evaluation of their interaction with glutamate receptors

Chemistry and Biodiversity

Volumn 5, Issue 4, 2008, Pages 657-663

  Conti, Paola ^a   di Ventimiglia, Samuele Joppolo ^a   Pinto, Andrea ^a   Tamborini, Lucia ^a   Menniti, Frank S ^b   Lazzaro, John T ^b   De Micheli, Carlo ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,3A,4,5,6,6A HEXAHYDRO 1 METHYLPYRROLO[3,4 D]PYRAZOLE 3,4 DICARBOXYLIC ACID; 1,3A,4,5,6,6A HEXAHYDRO 1 METHYLPYRROLO[3,4 D]PYRAZOLE 3,6 DICARBOXYLIC ACID; 1,3A,4,5,6,6A HEXAHYDRO 1 PHENYLPYRROLO[3,4 D]PYRAZOLE 3,4 DICARBOXYLIC ACID; 1,3A,4,5,6,6A HEXAHYDRO 1 PHENYLPYRROLO[3,4 D]PYRAZOLE 3,6 DICARBOXYLIC ACID; AMPA RECEPTOR; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE RECEPTOR ANTAGONIST; NEUROTRANSMITTER RECEPTOR; PYRROLO[3,4 D]PYRAZOLE DICARBOXYLIC ACID; UNCLASSIFIED DRUG; CALCIUM; DICARBOXYLIC ACID; PYRAZOLE DERIVATIVE;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CONCENTRATION RESPONSE; CYCLOADDITION; DRUG DETERMINATION; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; NERVE CELL; NONHUMAN; RAT; RECEPTOR BLOCKING; STRUCTURE ACTIVITY RELATION; ANIMAL; CEREBELLUM; DRUG EFFECT; METABOLISM; STEREOISOMERISM; SYNTHESIS;

ANIMALS; CALCIUM; CEREBELLUM; DICARBOXYLIC ACIDS; NEURONS; PYRAZOLES; RATS; RECEPTORS, AMPA; STEREOISOMERISM;

EID: 45549090284     PISSN: 16121872     EISSN: 16121880     Source Type: Journal    
DOI: 10.1002/cbdv.200890061     Document Type: Article

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