Characterization of the binding site for a novel class of noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonists

Molecular Pharmacology

Volumn 58, Issue 6, 2000, Pages 1310-1317

  Menniti, Frank S ^a,b   Chenard, Bertrand L ^a   Collins, Mary B ^a   Ducat, Mary F ^a   Elliott, Mark L ^a   Ewing, Frank E ^a   Huang, Jianhua I ^a   Kelly, Kristin A ^a   Lazzaro, John T ^a   Pagnozzi, Martin J ^a   Weeks, James L ^a   Welch, Willard M ^a   Frost White, W ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [2 [3 (2 CHLOROPHENYL) 6 FLUORO 4 OXO 3,4 DIHYDROQUINAZOLIN 2 YL]VINYL]NICOTINONITRILE; 3 (2 CHLOROPHENYL) 2 [2 (6 DIETHYLAMINOMETHYLPYRIDIN 2 YL)VINYL] 6 FLUORO 3H QUINAZOLIN 4 ONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; BENZODIAZEPINE DERIVATIVE; CP 465022; CP 526427; GLUTAMIC ACID; IONOTROPIC RECEPTOR; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL TISSUE; DRUG BINDING SITE; DRUG POTENCY; DRUG RECEPTOR BINDING; FOREBRAIN; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; SHORT SURVEY; SYNAPTIC TRANSMISSION;

EID: 0033675261     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.58.6.1310     Document Type: Short Survey

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