Barrier function and water-holding and transport properties of infant stratum corneum are different from adult and continue to develop through the first year of life

Journal of Investigative Dermatology

Volumn 128, Issue 7, 2008, Pages 1728-1736

  Nikolovski, Janeta ^a   Stamatas, Georgios N ^a   Kollias, Nikiforos ^a   Wiegand, Benjamin C ^a  

^a JOHNSON AND JOHNSON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; DESORPTION; GESTATIONAL AGE; HUMAN; HYDRATION; INFANT; MEASUREMENT; PRIORITY JOURNAL; RAMAN SPECTROMETRY; SKIN CONDUCTANCE; SKIN WATER LOSS; STRATUM CORNEUM; WATER TRANSPORT; AGE; AGED; BODY WATER; EPIDERMIS; METABOLISM; MIDDLE AGED; PRESCHOOL CHILD; SKIN ABSORPTION; TRANSPORT AT THE CELLULAR LEVEL;

ADOLESCENT; ADULT; AGE FACTORS; AGED; BIOLOGICAL TRANSPORT; BODY WATER; CHILD, PRESCHOOL; EPIDERMIS; HUMANS; INFANT; MIDDLE AGED; SKIN ABSORPTION;

EID: 45549088607     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5701239     Document Type: Article

References (48)

1. Agren JSG, Sedin G (2006) Ambient humidity influences the rate of skin barrier maturation in extremely preterm infants. J Pediatr 148:613-7
2. Behne MJ, Barry NP, Hanson KM, Aronchik I, Clegg RW, Gratton E et al. (2003) Neonatal development of the stratum corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function. J Invest Dermatol 120:998-1006
3. Berardesca E (1997) EEMCO guidance for the assessment of stratum corneum hydration: electrical methods. Skin Res Technol 3:126-32
4. Bouwstra JA, de Graaff A, Gooris GS, Nijsse J, Wiechers JW, van Aelst AC (2003) Water distribution and related morphology in human stratum corneum at different hydration levels. J Invest Dermatol 120:750-8
5. Cartlidge P (2000) The epidermal barrier. Semin Neonatol 5:273-80
6. Caspers PJ, Lucassen GW, Carter EA, Bruining HA, Puppels GJ (2001) In vivo confocal Raman microspectroscopy of the skin: noninvasive determination of molecular concentration profiles. J Invest Dermatol 116:434-42
7. Caspers PJ, Lucassen GW, Puppels GJ (2003) Combined in vivo confocal Raman spectroscopy and confocal microscopy of human skin. Biophy J 85:572-80
8. Chilcott RP, Dalton CH, Emmanuel AJ, Allen CE, Bradley ST (2002) Transepidermal water loss does not correlate with skin barrier function in vitro. J Invest Dermatol 118:871-5
9. Chiou YB, Blume-Peytavi U (2004) Stratum corneum maturation. A review of neonatal skin function. Skin Pharmacol Physiol 17:57-66
10. Chou TC, Lin KH, Wang SM, Lee CW, Su SB, Shih TS et al. (2005) Transepidermal water loss and skin capacitance alterations among workers in an ultra-low humidity environment. Arch Dermatol Res 296:489-95
11. Denda M, Sato J, Masuda Y, Tsuchiya T, Koyama J, Kuramoto M et al. (1998) Exposure to a dry environment enhances epidermal permeability barrier function. J Invest Dermatol 111:858-63
12. Egawa M, Hirao T, Takahashi M (2007) In vivo estimation of stratum corneum thickness from water concentration profiles obtained with Raman spectroscopy. Acta Derm Venereol 87:4-8
13. Elias PM (2005) Stratum corneum defensive functions: an integrated view [see comment]. J Invest Dermatol 125:183-200
14. Evans NJ, Rutter N (1986) Development of the epidermis in the newborn. Biol Neonate 49:74-80
15. Fluhr JW, Mao-Qiang M, Brown BE, Hachem JP, Moskowitz DG, Demerjian M et al. (2004) Functional consequences of a neutral pH in neonatal rat stratum corneum. J Invest Dermatol 123:140-51
16. Giusti F, Martella A, Bertoni L, Seidenari S (2001) Skin barrier, hydration, and pH of the skin of infants under 2 years of age. Pediatr Dermatol 18:93-6
17. Hanifin JM, Thurston M, Omoto M, Cherill R, Tofte SJ, Graeber M (2001) The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis. EASI Evaluator Group. Exp Dermatol 10:11-8
18. Harpin VA, Rutter N (1983) Barrier properties of the newborn infant's skin. J Pediatr 102:419-25
19. Hellemans L, van der Pol A, van Overloop L, Riggs WM, Declercq L, Maes D (2005) In vivo measurement of dynamics of water movement across the stratum corneum after barrier disruption. J Invest Dermatol 125 (Suppl S):A11065
20. Hernes KG, Morkrid L, Fremming A, Odegarden S, Martinsen OG, Storm H (2002) Skin conductance changes during the first year of life in full-term infants. Pediatr Res 52:837-43
21. Hoath SB (1997) The stickiness of newborn skin: bioadhesion and the epidermal barrier [comment]. J Pediatr 131:338-40
22. Hoeger PH, Enzmann CC (2002) Skin physiology of the neonate and young infant: a prospective study of functional skin parameters during early infancy. Pediatr Dermatol 19:256-62
23. Holbrook KA (2000) Embryogenesis of the skin. Oxford: Blackwell Science
24. Holbrook KA (1982) A histological comparison of infant and adult skin. New York: Marcel Dekker Inc.
25. Kalia YN, Nonato LB, Lund CH, Guy RH (1998) Development of skin barrier function in premature infants. J Invest Dermatol 111:320-6
26. Kikuchi K, Kobayashi H, O'Goshi K, Tagami H (2006) Impairment of skin barrier function is not inherent in atopic dermatitis patients: a prospective study conducted in newborns. Pediatr Dermatol 23:109-13
27. Lund CH, Nonato LB, Kuller JM, Franck LS, Cullander C, Durand DJ (1997) Disruption of barrier function in neonatal skin associated with adhesive removal [see comment]. J Pediatr 131:367-72
28. Mancini AJ (2004) Skin. Pediatrics 113:1114-9
29. Menon GK (2002) New insights into skin structure: scratching the surface. Adv Drug Deliv Rev 54(Suppl 1):S3-17
30. Norlen L (2001) Skin barrier structure and function: the single gel phase model. J Invest Dermatol 117:830-6
31. Pierard GE, Goffin V, Hermanns-Le T, Pierard-Franchimont C (2000) Corneocyte desquamation. Int J Mol Med 6:217-21
32. Rawlings AV, Harding CR (2004) Moisturization and skin barrier function. Dermatol Ther 17(Suppl 1):43-8
33. Rawlings AV, Matts PJ (2005) Stratum corneum moisturization at the molecular level: an update in relation to the dry skin cycle. J Invest Dermatol 124:1099-110
34. Rawlings AV, Scott IR, Harding CR, Bowser PA (1994) Stratum corneum moisturization at the molecular level. J Invest Dermatol 103:731-41
35. Rogiers V (2001) EEMCO guidance for the assessment of transepidermal water loss in cosmetic sciences. Skin Pharmacol Appl Skin Physiol 14:117-28
36. Rutter N (2000a) Clinical consequences of an immature barrier. Semin Neonatol 5:281-7
37. Rutter N (2000b) Physiology of the newborn skin. Oxford: Blackwell Science
38. Rutter N, Hull D (1979) Water loss from the skin of term and preterm babies. Arch Dis Child 54:858-68
39. Saijo S, Tagami H (1991) Dry skin of newborn infants: functional analysis of the stratum corneum. Pediatr Dermatol 8:155-9
40. Sato J, Yanai M, Hirao T, Denda M (2000) Water content and thickness of the stratum corneum contribute to skin surface morphology. Arch Dermatol Res 292:412-7
41. Segre J (2003) Complex redundancy to build a simple epidermal permeability barrier. Curr Opin Cell Biol 15:776-82
42. Tagami H, Kanamaru Y, Inoue K, Suehisa S, Inoue F, Iwatsuki K et al. (1982) Water sorption-desorption test of the skin in vivo for functional assessment of the stratum corneum. J Invest Dermatol 78:425-8
43. Visscher MO, Chatterjee R, Ebel JP, LaRuffa AA, Hoath SB (2002) Biomedical assessment and instrumental evaluation of healthy infant skin. Pediatr Dermatol 19:473-81
44. Visscher MO, Chatterjee R, Munson KA, Pickens WL, Hoath SB (2000) Changes in diapered and nondiapered infant skin over the first month of life. Pediatr Dermatol 17:45-51
45. Visscher MO, Narendran V, Pickens WL, LaRuffa AA, Meinzen-Derr J, Allen K et al. (2005) Vernix caseosa in neonatal adaptation. J Perinatol 25:440-6
46. Wilson DR, Maibach HI (1982) Transepidermal water loss. New York: Marcel Dekker Inc.
47. Wilson DR, Maibach HI (1980) Transepidermal water loss in vivo. Premature and term infants. Biol Neonate 37:180-5
48. Yosipovitch G, Maayan-Metzger A, Merlob P, Sirota L (2000) Skin barrier properties in different body areas in neonates. Pediatrics 106:105-8