Developmental changes in expression and self-editing of adenosine deaminase type 2 pre-mRNA and mRNA in rat brain and cultured cortical neurons

Neuroscience Research

Volumn 61, Issue 4, 2008, Pages 398-403

  Hang, Pham Nguyet Thi ^a   Tohda, Michihisa ^a   Matsumoto, Kinzo ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Adenosine deaminase; Depression; Fetal rat brain; Neuronal development; Primary cultured neuron; RNA editing; Serotonin 2C receptor

Indexed keywords

ADENOSINE DEAMINASE; MESSENGER RNA; MESSENGER RNA PRECURSOR; SEROTONIN 2C RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN DEVELOPMENT; BRAIN MATURATION; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; FETUS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE TARGETING; GESTATIONAL AGE; MENTAL DISEASE; NERVE CELL DIFFERENTIATION; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; RNA EDITING;

ADENOSINE DEAMINASE; AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; BRAIN; CELLS, CULTURED; EMBRYO, MAMMALIAN; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; NEURONS; PREGNANCY; RATS; RATS, WISTAR; RNA EDITING; RNA PRECURSORS; RNA, MESSENGER;

EID: 45449100706     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2008.04.007     Document Type: Article

References (32)

1. Bass B.L. RNA editing and hypermutation by adenosine deamination. Trends Biochem. Sci. 22 (1997) 157-162
2. Bass B.L. RNA editing by adenosine deaminases that act on RNA. Annu. Rev. Biochem. 71 (2002) 817-846
3. Brewer G.J. Serum-free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gynus. J. Neurosci. Res. 42 (1995) 674-683
4. Burns C.M., Chu H., Rueter S.M., Hutchinson L.K., Canton H., Sanders-Bush E., and Emeson R.B. Regulation of serotonin-2C receptor G-protein coupling by RNA editing. Nature 387 (1997) 303-308
5. Cavaille J., Buiting K., Klefmann M., Lalande M., Brannan C.I., Horsthemke B., Bachellerie J.P., Brosius J., and Huttenhofer A. Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization. Proc. Natl. Acad. Sci. U.S.A. 97 (2000) 14311-14316
6. Chen C.X., Cho D.S., Wang Q., Lai F., Carter K.C., and Nishikura K. A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains. RNA 6 (2000) 755-767
7. Choi D.W. Calcium: still center-stage in hypoxic-ischemic neuronal death. Trends Neurosci. 18 (1995) 58-60
8. Dawson T.R., Sansam C.L., and Emeson R.B. Structure and sequence determinants required for the RNA editing of ADAR-2 substrates. J. Biol. Chem. 279 (2004) 4941-4951
9. Feng Y., Sansam C.L., Singh M., and Emeson R.B. Altered RNA editing in mice lacking ADAR-2 autoregulation. Mol. Cell. Biol. 26 (2006) 480-488
10. Gan Z., Zhao L., Yang L., Huang P., Zhao F., Li W., and Liu Y. RNA editing by ADAR-2 is metabolically regulated in pancreatic islets and beta -cells. J. Biol. Chem. 281 (2006) 33386-33394
11. Gerber A., Grosjean H., Melcher T., and Keller W. Tad1p, a yeast tRNA-specific adenosine deaminase, is related to the mammalian pre-mRNA editing enzymes ADAR1 and ADAR2. EMBO J. 17 (1998) 4780-4789
12. Gurevich I., Tamir H., Arango V., Dwork A.J., Mann J.J., and Schmauss C. Altered editing of serotonin 2C receptor pre-mRNA in the prefrontal cortex of depressed suicide victims. Neuron 34 (2002) 349-356
13. Higuchi M., Maas S., Single F.N., Hartner J., Rozov A., Burnashev N., Feldmeyer D., Sprengel R., and Seeburg P.H. Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR-2. Nature 406 (2000) 78-81
14. Iwamoto K., and Kato T. RNA editing of serotonin 2C receptor in human postmortem of major mental disorders. Neurosci. Lett. 346 (2003) 169-172
15. Keegan L.P., Gallo A., and O'Connell M.A. Development: survival is impossible without an editor. Science 290 (2000) 1707-1709
16. Kim U., Wang Y., Sanford T., Zeng Y., and Nishikura K. Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 11457-11461
17. Laxminarayana D., O'Rourke K.S., Maas S., and Olorenshaw I. Altered editing in RNA editing adenosine deaminase ADAR-2 gene transcripts of systemic lupus erythematosus T lymphocytes. Immunology 121 (2007) 359-369
18. Maas S., Patt S., Schrey M., and Rich A. Underediting of glutamate receptor GluR-B mRNA in malignant gliomas. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 14687-14692
19. Melcher T., Maas S., Herb A., Sprengel R., Higuchi M., and Seeburg P.H. RED2, a brain-specific member of the RNA-specific adenosine deaminase family. J. Biol. Chem. 271 (1996) 31795-31798
20. Melcher T., Maas S., Herb A., Sprengel R., Seeburg P.H., and Higuchi M. A mammalian RNA editing enzyme. Nature 379 (1996) 460-464
21. Niswender C.M., Herrick-Davis K., Dilley G.E., Meltzer H.Y., Overholser J.C., Stockmeier C.A., Ronald B., Emeson R.B., and Sanders-Bush E. RNA editing of the human serotonin 5-HT2C receptor: alterations in suicide and implications for serotonergic pharmacotherapy. Neuropsychopharmacology 24 (2001) 478-491
22. O'Connell M.A., Krause S., Higuchi M., Hsuan J.J., Totty N.F., Jenny A., and Keller W. Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase. Mol. Cell. Biol. 15 (1995) 1389-1397
23. Ohlson J., Pedersen J.S., Haussler D., and Ohman M. Editing modifies the GABA(A) receptor subunit alpha3. RNA 13 (2007) 698-703
24. + channel transcript in a region of RNA editing. Neuron 25 (2000) 139-149
25. Rueter S.M., Dawson T.R., and Emeson R.B. Regulation of alternative splicing by RNA editing. Nature 399 (1999) 75-80
26. Seeburg P.H. RNA helicase participates in the editing game. Neuron 25 (2000) 261-263
27. Sommer B., Köhler M., Sprengel R., and Seeburg P.H. RNA editing in brain controls a determinant of ion flow in glutamate-gated channels. Cell 67 (1991) 11-19
28. Tohda M., Sukma M., Hang T.N.P., and Matsumoto K. RNA editing and short variant of 5-HT2C receptor in neuronal differentiated cells. J. Pharmacol. Sci. 101 Suppl. (2006) 92
29. Tohda M., Hang T.N.P., Sukma M., and Matsumoto K. Chronoroglical change of serotonin 2C receptor mRNA short variant and its RNA editing. Folia Pharmacologica Japonica 131 (2008) 4P
30. Tohda, M, Hang, T.N.P., Matsumoto, K., submitted for publication. Influences of changes in serotonin 2C receptor mRNA editing on neuronal development and neurite outgrowth activity in rat brains and cultured cortical neurons.
31. Tonkin L.A., Saccomanno L., Morse D.P., Brodigan T., Krause M., and Bass B.L. RNA editing by ADARs is important for normal behavior in Caenorhabditis elegans. EMBO J. 21 (2002) 6025-6035
32. Wang Q., Khillan J., Gadue P., and Nishikura K. Requirement of the RNA editing deaminase ADAR-1 gene for embryonic erythropoiesis. Science 290 (2000) 1765-1768