A facile and effective synthesis of lipophilic 2,6-diketopiperazine analogues

Tetrahedron

Volumn 64, Issue 28, 2008, Pages 6749-6754

  Fytas, Christos ^a   Zoidis, Grigoris ^a   Fytas, George ^a  

^a UNIVERSITY OF ATHENS   (Greece)

Author keywords

2,6 Diketopiperazines; Base induced cyclization; NMR; Potassium bis(trimethylsilyl)amide

Indexed keywords

1,4 DIAZSPIRO[5,7]TRIDECANE 3,5 DIONE; 3 (TRICYCLO[3.3.1.1 3,7]DEC 1 YL) 2,6 DIOXOPIPERAZINE 1 ACETIC ACID; 3 (TRICYCLO[3.3.1.1 3,7]DEC 1 YL) 2,6 DIOXOPIPERAZINE 1 ACETIC ACID BENZYL ESTER; 3 (TRICYCLO[3.3.11 3,7]DEC 1 YL) 2,6 PIPERAZINEDIONE; 3,5 DIOXO 1,4 DIAZASPIRO[5.7]TRIDECANE 4 ACETIC ACID; 3,5 DIOXO 1,4 DIAZASPIRO[5.7]TRIDECANE 4 ACETIC ACID BENZYL ESTER; 3,5 DIOXOSPIRO[PIPERAZINE 2,2' TRICYCLO[3.3.1.1 3,7]DECANE] 4 ACETIC ACID; 3,5 DIOXOSPIRO[PIPERAZINE 2,2' TRICYCLO[3.3.1.1 3,7]DECANE] 4 ACETIC ACID BENZYL ESTER; 6 METHYL 3,5 DIOXOSPIRO[PIPERAZINE 2,2' TRICYCLO[3.3.1.1 3,7]DECANE] 4 ACETIC ACID; 6 METHYL 3,5 DIOXOSPIRO[PIPERAZINE 2,2' TRICYCLO[3.3.1.1 3,7]DECANE] 4 ACETIC ACID BENZYL ESTER; 6 METHYLSPIRO[PIPERAZINE 2,2' TRICYCLO[3.3.1.1 3,7]DECANE] 3,5 DIONE; ADAMANTANE; N (1 AMINOCARBONYLCYCLOOCTYL)GLYCINE ETHYL ESTER; N [2 AMINOCARBONYL(TRICYCLO[3.3.1.1 3,7]DEC 2 YL)]GLYCINE ETHYL ESTER; N [2 AMINOCARBONYL9TRICYCLO[3.3.1.1 3,7]DEC 2 YL)] ALANINE ETHYL ESTER; N [2 CYANO(TRICYCLO[3.3.1.1 3,7]DEC 2 YL)] ALANINE ETHYL ESTER; N [2 CYANO(TRICYCLO[3.3.1.1 3,7]DEC 2 YL)]GLYCINE ETHYL ESTER; N [AMINOCARBONYL(TRICYCLO[3.3.1.1 3,7]DEC 1 YL)METHYL] GLYCINE ETHYL ESTER; PIPERAZINE DERIVATIVE; SPIRO[PIPERAZINE 2,2' TRICYCLO[3.3.1.1 3,7]DECANE] 3,5 DIONE;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLIZATION; HYDROGENOLYSIS; PRIORITY JOURNAL; SYNTHESIS;

EID: 45449100129     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2008.05.005     Document Type: Article

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