Negative regulation of hepatocellular carcinoma cell growth by signal regulatory protein α1

Hepatology

Volumn 40, Issue 3, 2004, Pages 618-628

  Yan, He Xin ^a   Wang, Hong Yang ^a   Zhang, Rui ^a   Chen, Lei ^a   Li, Bao An ^a   Liu, Shu Qin ^a   Cao, Hui Fang ^a   Qiu, Xiu Hua ^a   Shan, Yun Feng ^a   Yan, Zhong Hua ^a   Wu, Hong Ping ^a   Tan, Ye Xiong ^a   Wu, Meng Chao ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGENIC AGENT; MUTANT PROTEIN; PROTEIN TYROSINE PHOSPHATASE SHP 2; REGULATOR PROTEIN; SIGNAL REGULATORY PROTEIN ALPHA1; TYROSINE; UNCLASSIFIED DRUG; DIFFERENTIATION ANTIGEN; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 3; NERVE CELL ADHESION MOLECULE L1; PROTEIN TYROSINE PHOSPHATASE; SIGNAL PEPTIDE; SRC HOMOLOGY 2 (SH2) DOMAIN CONTAINING PHOSPHATASES; SRC HOMOLOGY-2 (SH2) DOMAIN-CONTAINING PHOSPHATASES;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL LINE; CELL MIGRATION; CELL SPREADING; CELL STRAIN HUH7; COMPLEX FORMATION; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; APOPTOSIS; CELL DIVISION; CELL MOTION; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; LIVER TUMOR; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ANTIGENS, DIFFERENTIATION; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL DIVISION; CELL MOVEMENT; ENZYME ACTIVATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER NEOPLASMS; MEMBRANE GLYCOPROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NEURAL CELL ADHESION MOLECULE L1; NF-KAPPA B; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, IMMUNOLOGIC;

EID: 4544318732     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.20360     Document Type: Article

References (42)

1. Kharitonenkov A, Chen Z, Sures I, Wang H, Schilling J, Ullrich A. A family of proteins that inhibit signalling through tyrosine kinase receptors. Nature 1997;386:181-186.
2. Cambier JC. Inhibitory receptors abound? Proc Natl Acad Sci U S A 1997;94:5993-5995.
3. Oshima K, Ruhul Amin AR, Suzuki A, Hamaguchi M, Matsuda S. SHPS-1, a multifunctional transmembrane glycoprotein. FEBS Lett 2002;519:1-7.
4. Shi ZQ, Lu W, Feng GS. The Shp-2 tyrosine phosphatase has opposite effects in mediating the activation of extracellular signal-regulated and c-Jun NH2-terminal mitogen-activated protein kinases. J Biol Chem 1998;273:4904-4908.
5. Takada T, Matozaki T, Takeda H, Fukunaga K, Noguchi T, Fujioka Y, et al. Roles of the complex formation of SHPS-1 with SHP-2 in insulin-stimulated mitogen-activated protein kinase activation. J Biol Chem 1998;273:9234-9242.
6. Oshima K, Machida K, Ichigotani Y, Nimura Y, Shirafuji N, Hamaguchi M, et al. SHPS-1: a budding molecule against cancer dissemination. Cancer Res 2002;62:3929-3933.
7. Inagaki K, Yamao T, Noguchi T, Matozaki T, Fukunaga K, Takada T, Hosooka T, et al. SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility. EMBO J 2000;19:6721-6731.
8. Wu CJ, Chen Z, Ullrich A, Greene MI, O'Rourke DM. Inhibition of EGFR-mediated phosphoinositide-3-OH kinase (PI3-K) signaling and glioblastoma phenotype by signal-regulatory proteins (SIRPs). Oncogene 2000;19:3999-4010.
9. Neznanov N, Neznanova L, Kondratov RV, Burdelya L, Kandel ES, O'Rourke DM, et al. Dominant negative form of signal-regulatory protein-alpha (SIRPalpha/SHPS-1) inhibits tumor necrosis factor-mediated apoptosis by activation of NF-kappa B. J Biol Chem 2003;278:3809-3815.
10. Motegi S, Okazawa H, Ohnishi H, Sato R, Kaneko Y, Kobayashi H, et al. Role of the CD47-SHPS-1 system in regulation of cell migration. EMBO J 2003;22:2634-2644.
11. Jiang P, Lagenaur CF, Narayanan V. Integrin-associated protein is a ligand for the P84 neural adhesion molecule. J Biol Chem 1999;274:559-562.
12. Timms JF, Swanson KD, Marie-Cardine A, Raab M, Rudd CE, Schraven B, et al. SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages. Curr Biol 1999;9:927-930.
13. Seiffert M, Cant C, Chen Z, Rappold I, Brugger W, Kanz L, et al. Human signal-regulatory protein is expressed on normal, but not on subsets of leukemic myeloid cells and mediates cellular adhesion involving its counterreceptor CD47. Blood 1999;11:3633-3643.
14. You BM, Flick ML, Yu D, Feng GS. Modulation of the nuclear factor kappaB pathway by Shp-2 tyrosine phosphatase in mediating the induction of interleukin (IL)-6 by IL-1 or tumor necrosis factor. J Exp Med 2001;193:101-109.
15. Wang H, Lian Z, Lerch MM, Chen Z, Xie W, Ullrich A. Characterization of PCP-2, a novel receptor protein tyrosine phosphatase of the MAM domain family. Oncogene 1996;12:2555-2562.
16. Yan HX, He YQ, Dong H, Zhang P, Zeng JZ, Cao HF, et al. Physical and functional interaction between receptor-like protein tyrosine phosphatase PCP-2 and beta-catenin. Biochemistry 2002;41:15854-15860.
17. Hinz M, Krappmann D, Eichten A, Heder A, Scheidereit C, Strauss M. NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition. Mol Cell Biol 1999;19:2690-2698.
18. Yu DH, Qu CK, Henegariu O, Lu X, Feng GS. Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion. J Biol Chem 1998;273:21125-21131.
19. Shao R, Hu MC, Zhou BP, Lin SY, Chiaoi PJ, Lindern RH, et al. E1A sensitizes cells to tumor necrosis factor-induced apoptosis through inhibition of IkappaB kinases and nuclear factor kappaB activities. J Biol Chem 1999;31:21495-21498
20. Li B, Wang H, Chen Z, Wu M. Expression of signal-regulatory protein alpha in hepatocellular carcinoma [in Chinese]. Zhonghua Zhong Liu Za Zhi 1998;20:345-347.
21. Li B, Wang H, Chen Z, Wu M. The association between signal-regulatory protein alpha and hepatocellular carcinoma [in Chinese]. Zhonghua Yi Xue Za Zhi 1999;79:268-270.
22. Liedtke C, Plumpe J, Kubicka S, Bradham CA, Manns MP, Brenner DA, et al. Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells. HEPATOLOGY 2002;36:315-325.
23. Tsujimoto Y. Role of Bcl-2 family proteins in apoptosis: apoptosomes or mitochondria? Genes Cells 1998;3:3697-3707.
24. Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB. NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 1999;401:82-85.
25. Kapoor GS, Zhan Y, Johnson GR, O'Rourke DM. Distinct domains in the SHP-2 phosphatase differentially regulate epidermal growth factor receptor/NF-kappaB activation through Gab1 in glioblastoma cells. Mol Cell Biol 2004;24:823-836.
26. Tsuda M, Matozaki T, Fukunaga K, Fujioka Y, Imamoto A, Noguchi T, et al. Integrin-mediated tyrosine phosphorylation of SHPS-1 and its association with SHP-2. Roles of Fak and Src family kinases. J Biol Chem 1998;273:13223-13229.
27. Oh ES, Gu H, Saxton TM, Timms JF, Hausdorff S, Frevert EU, et al. Regulation of early events in integrin signaling by protein tyrosine phosphatase SHP-2. Mol Cell Biol 1999;19:3205-3215.
28. Tang TL, Freeman RM Jr, O'Reilly AM, Neel BG, and Sokol SY. The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required up-stream of MAP kinase for early Xenopus development. Cell 1995;80:473-483.
29. Shi ZQ, Lu W, Feng GS. The Shp-2 tyrosine phosphatase has opposite effects in mediating the activation of extracellular signal-regulated and c-Jun NH2-terminal mitogen-activated protein kinases. J Biol Chem 1998;273:4904-4908.
30. Noguchi T, Matozaki T, Horita K, Fujioka Y, Kasuga M. Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation. Mol Cell Biol 1994;4:6674-6682.
31. Milarski KL, Saltiel AR. Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin. J Biol Chem 1994;269:21239-21243.
32. Fujioka Y, Matozaki T, Noguchi T, Iwamatsu A, Yamao T, Takahashi N, et al. A novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesion. Mol Cell Biol 1996;16:6887-6899.
33. Yamauchi K, Ribon V, Saltiel AR, Pessin JE. Identification of the major SHPTP2-binding protein that is tyrosine-phosphorylated in response to insulin. J Biol Chem 1995;270:17716-17722.
34. Karin M, Cao Y, Greten FR, Li ZW. NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2002;2:301-310.
35. Sanchez-Perez I, Benitah SA, Martinez-Gomariz M, Lacal JC, Perona R. Cell stress and MEKK1-mediated c-Jun activation modulate NFkappaB activity and cell viability. Mol Biol Cell 2002;13:2933-2945.
36. Potapova O, Basu S, Mercola D, Holbrook NJ. Protective role for c-Jun in the cellular response to DNA damage. J Biol Chem 2001;276:28546-28553.
37. Amit S, Ben-Neriah Y. NF-kappaB activation in cancer: a challenge for ubiquitination- and proteasome-based therapeutic approach. Semin Cancer Biol 2003;13:15-28.
38. Takehara T, Liu X, Fujimoto J, Friedman SL, Takahashi H. Expression and role of Bcl-xL in human hepatoellular carcinomas. HEPATOLOGY 2001;34:55-61.
39. Inagaki K, Noguchi T, Matozaki T, Horikawa T, Fukunaga K, Tsuda M, et al. Roles for the protein tyrosine phosphatase SHP-2 in cytoskeletal organization, cell adhesion and cell migration revealed by overexpression of a dominant negative mutant. Oncogene 2000;19:75-84.
40. Anand-Apte B, Zetter BR, Viswanathan A, Qiu RG, Chen J, Ruggieri R, et al. Platelet-derived growth factor and fibronectin-stimulated migration are differentially regulated by the Rac and extracellular signal-regulated kinase pathways. J Biol Chem 1997;272:30688-30692.
41. Klemke RI, Cai S, Giannini AL, Gallagher PJ, de Lanerolle P, Cheresh DA. Regulation of cell motility by mitogen-activated protein kinase. J Cell Biol 1997;137:481-492.
42. Neaud V, Faouzi S, Guirouilh J, Le Bail B, Balabaud C, Bioulac-Sage P, et al. Human hepatic myofibroblasts increase invasiveness of hepatocellular carcinoma cells: evidence for a role of hepatocyte growth factor. HEPATOLOGY 1997;26:1458-1466.