Effect of daidzein on cell growth, cell cycle, and telomerase activity of human cervical cancer in vitro

International Journal of Gynecological Cancer

Volumn 14, Issue 5, 2004, Pages 882-888

  Guo, Jun Ming ^a   Kang, G Z ^b   Xiao, B X ^a   Liu, D H ^c   Zhang, S ^c  

^a NINGBO UNIVERSITY   (China)

^b GANNAN MEDICAL UNIVERSITY   (China)

^c NINGBO NO 2 HOSPITAL   (China)

Author keywords

Cell cycle; Cell growth; Cervical tumor; Daidzein; Telomerase

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; DAIDZEIN; MESSENGER RNA; PHYTOESTROGEN; TELOMERASE;

APOPTOSIS; ARTICLE; CANCER CELL; CATALYSIS; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL GROWTH; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVITY; FEMALE; FLOW CYTOMETRY; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UTERINE CERVIX CARCINOMA;

APOPTOSIS; CELL CYCLE; CELL PROLIFERATION; FEMALE; HELA CELLS; HUMANS; ISOFLAVONES; PHYTOESTROGENS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TELOMERASE; UTERINE CERVICAL NEOPLASMS;

EID: 4544312893     PISSN: 1048891X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1048-891X.2004.14525.x     Document Type: Article

References (22)

1. Tham DM, Gardner CD, Haskell WL. Potential health benefits of dietary phytoestrogens: a review of the clinical, epidemiological, and mechanistic evidence. J Clin Endocrinol Metab 1998;83:2223-35.
2. Messina M, Barnes S. The role of soy products in reducing risk of cancer. J Natl Cancer Inst 1991;83:541-6.
3. Zhou JR, Mukherjee P, Gugger ET, Tanaka T, Blackburn GL, Clinton SK. Inhibition of murine bladder tumorigenesis by soy isoflavones via alterations in the cell cycle, apoptosis, and angiogenesis. Cancer Res 1998;58:5231-8.
4. Maggiolini M, Bonofiglio D, Marsico S et al. Estrogen receptor α mediates the proliferative but not the cytotoxic dose-dependent effects of two major phytoestrogens on human breast cancer cells. Mol Pharmacol 2001;60:595-602.
5. Liu HS, Chen CY, Lee CH, Chou YI. Selective activation of oncogenic Ha-ras-induced apoptosis in NIH/3T3 cells. Br J Cancer 1998;77:1777-89.
6. Emig M, Saussele S, Wittor H et al. Accurate and rapid analysis of residual disease in patients with CML using specific fluorescent hybridization probes for real time quantitative RT-PCR. Leukemia 1999;13:1825-32.
7. Bingham SA, Atkinson C, Liggins J, Bluck L, Coward A. Phytoestrogens: where are we now? Br J Nutr 1998;79:393-406.
8. Messina MJ, Loprinzi CL. Soy for breast cancer survivors: a critical review of the literature. J Nutr 2001;131:3095S-108S.
9. Liggins J, Bluck LJ, Runswick S, Atkinson C, Coward WA, Bingham SA. Daidzein and genistein content of fruits and nuts. J Nutr Biochem 2000;11:326-31.
10. Knight DC, Eden JA. A review of the clinical effects of phytoestrogens. Obstet Gynecol 1996;87:897-904.
11. Setchell KDR. Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones. Am J Clin Nutr 1998;68:1333S-46S.
12. Su SJ, Yeh TM, Lei HY, Chow NH. The potential of soybean foods as a chemoprevention approach for human urinary tract cancer. Clin Cancer Res 2000;6:230-6.
13. Constantinon AI, Mehta RG, Vaughan A. Inhibition of N-methyl-N- nitrosourea-induced mammary tumors in rats by the soybean isoflavones. Anticancer Res 1996; 16:3293-8.
14. Casagrande F, Darbon JM. Effects of structurally related flavonoids on cell cycle progression of human melanoma cells: regulation of cyclin-dependent kinases CDK2 and CDK1. Biochem Pharmacol 2001;61:1205-15.
15. Matsukawa Y, Marui N, Sakai T et al. Genistein arrests cell cycle progression at G2-M. Cancer Res 1993;53: 1328-31.
16. Peterson G. Evaluation of the biochemical targets of genistein in tumor cells. J Nutr 1995;125:784S-9S.
17. Shay JW, Wright WE. Telomerase activity in human cancer. Curr Opin Oncol 1996;8:66-71.
18. Schrader M, Burger AM, Müler M et al. Quantification of human telomerase reverse transcriptase mRNA in testicular germ cell tumors by quantitative fluorescence real-time RT-PCR. Oncol Rep 2002;9:1097-105.
19. Schrader M, Muller M, Heicappell R, Straub B, Miller K. Quantification of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) mRNA in testicular tissue of infertile patients. Asian J Androl 2001;3:263-70.
20. Ding Z, Green AG, Yang X, Chernenko G, Tang SC, Pater A. Retinoic acid inhibits telomerase activity and down-regulates expression but not affect splicing of hTERT: correlation with cell growth rate inhibition in an in vitro cervical carcinogenesis/multidrug-resistance model. Exp Cell Res 2002;272:185-91.
21. Raymond E, Sun D, Chen SF, Windle B, VonHoff DD. Agents that target telomerase and telomeres. Pharm Biotech 1996;7:583-91.
22. Rha SY, Izbicka E, Lawrence R et al. Effect of telomere and telomerase interactive agents on human tumor and normal cell lines. Clin Cancer Res 2000;6:987-93.