Improved, high yield synthesis of 3H-quinazolin-4-ones, the key intermediates of recently developed drugs

Current Medicinal Chemistry

Volumn 11, Issue 19, 2004, Pages 2549-2553

  Örfi, László ^a,b   Wáczek, Frigyes ^a   Pató, János ^b   Varga, István ^b   Hegymegi Barakonyi, Bálint ^a   Houghten, Richard A ^c   Kéri, György ^a,b  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b Vichem Chemie Ltd   (Hungary)

^c TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

Author keywords

Antiproliferative agents; Formamidine acetate; Imidoyl chlorides; Phosphodiesterase V inhibitors; Protein kinase inhibitors; Purine analogs; Pyrimidines; Quinazolin 4 ones

Indexed keywords

3H QUINAZOLIN 4 ONE; 4 (3 BROMOANILINO) 6,7 DIMETHOXYQUINAZOLINE; 8 METHYL 3H QUINAZOLIN 4 ONE; CYCLIC GMP PHOSPHODIESTERASE; GEFITINIB; KF 31327; PROTEIN KINASE; PROTEIN TYROSINE KINASE INHIBITOR; PURINE DERIVATIVE; PYRIMIDINE DERIVATIVE; QUINAZOLINE DERIVATIVE; SILDENAFIL; UNCLASSIFIED DRUG;

COMBINATORIAL CHEMISTRY; DRUG PURITY; DRUG STRUCTURE; DRUG SYNTHESIS; FOOD AND DRUG ADMINISTRATION; LUNG NON SMALL CELL CANCER; MICROWAVE RADIATION; MYELOPROLIFERATIVE DISORDER; PROTEIN EXPRESSION; REVIEW; SYSTEMATIC REVIEW; THERMAL STIMULATION;

EID: 4544297062     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867043364423     Document Type: Review

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