Enlarged infarct volume and loss of BDNF mRNA induction following brain ischemia in mice lacking FGF-2

Experimental Neurology

Volumn 189, Issue 2, 2004, Pages 252-260

  Kiprianova, Irina ^a   Schindowski, Katharina ^a   Von Bohlen Und Halbach, Oliver ^a   Krause, Sonja ^a   Dono, Rosanna ^b   Schwaninger, Markus ^a   Unsicker, Klaus ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UTRECHT UNIVERSITY   (Netherlands)

Author keywords

BDNF; Cerebral ischemia; FGF 2 KO; Hippocampus; Parietal cortex; trkB

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR 2; MESSENGER RNA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; CORRELATION ANALYSIS; HIPPOCAMPUS; KNOCKOUT MOUSE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; MOUSE MUTANT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WILD TYPE;

ANIMALS; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN-DERIVED NEUROTROPHIC FACTOR; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION; HIPPOCAMPUS; INFARCTION, MIDDLE CEREBRAL ARTERY; MICE; MICE, KNOCKOUT; RECEPTOR, TRKB; RNA, MESSENGER;

EID: 4544267683     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.expneurol.2004.06.004     Document Type: Article

References (59)

1. Abraham J.A., Whang J.L., Tumolo A., Mergia A., Friedman J., Gospodarowicz D., Fiddes J.C. Human basic fibroblast growth factor: nucleotide sequence and genomic organization. EMBO J. 5:1986;2523-2528
2. Arai S., Kinouchi H., Akabane A., Owada Y., Kamii H., Kawase M., Yoshimoto T. Induction of brain-derived neurotrophic factor (BDNF) and the receptor trkB mRNA following middle cerebral artery occlusion in rat. Neurosci. Lett. 211:1996;57-60
3. Beck T., Lindholm D., Castren E., Wree A. Brain-derived neurotrophic factor protects against ischemic cell damage in rat hippocampus. J. Cereb. Blood Flow Metab. 14:1994;689-692
4. Bederson J.B., Pitts L.H., Tsuji M., Nishimura M.C., Davis R.L., Bartkowski H. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke. 17:1986;472-476
5. Birren S.J., Anderson D.J. A v-myc-immortalized sympathoadrenal progenitor cell line in which neuronal differentiation is initiated by FGF but not NGF. Neuron. 4:1990;189-201
6. Boyd J.G., Gordon T. The neurotrophin receptors, trkB and p75, differentially regulate motor axonal regeneration. J. Neurobiol. 49:2001;314-325
7. Brumwell C.L., Hossain W.A., Morest D.K., Bernd P. Role for basic fibroblast growth factor (FGF-2) in tyrosine kinase (TrkB) expression in the early development and innervation of the auditory receptor: in vitro and in situ studies. Exp. Neurol. 162:2000;121-145
8. Bugra K., Pollard H., Charton G., Moreau J., Ben-Ari Y., Khrestchatisky M. aFGF, bFGF and flg mRNAs show distinct patterns of induction in the hippocampus following kainate-induced seizures. Eur. J. Neurosci. 6:1994;58-66
9. Connolly E.S. Jr., Winfree C.J., Stern D.M., Solomon R.A., Pinsky D.J. Procedural and strain-related variables significantly affect outcome in a murine model of focal cerebral ischemia. Neurosurgery. 38:1996;523-531
10. Conover J.C., Yancopoulos G.D. Neurotrophin regulation of the developing nervous system: analyses of knockout mice. Rev. Neurosci. 8:1997;13-27
11. Dono R., Texido G., Dussel R., Ehmke H., Zeller R. Impaired cerebral cortex development and blood pressure regulation in FGF-2-deficient mice. EMBO J. 17:1998;4213-4225
12. Ernsberger U., Patzke H., Rohrer H. The developmental expression of choline acetyltransferase (ChAT) and the neuropeptide VIP in chick sympathetic neurons: evidence for different regulatory events in cholinergic differentiation. Mech. Dev. 68:1997;115-126
13. Fisher M., Meadows M.E., Do T., Weise J., Trubetskoy V., Charette M., Finklestein S.P. Delayed treatment with intravenous basic fibroblast growth factor reduces infarct size following permanent focal cerebral ischemia in rats. J. Cereb. Blood Flow Metab. 15:1995;953-959
14. Gacek R.R., Khetarpal U., Schoonmaker J. Morphological and neurochemical correlates of vestibular compensation. Auris, Nasus, Larynx. 25:1998;193-201
15. Gomez-Pinilla F., Cotman C.W. Transient lesion-induced increase of basic fibroblast growth factor and its receptor in layer VIb (subplate cells) of the adult rat cerebral cortex. Neuroscience. 49:1992;771-780
16. Gomez-Pinilla F., Lee J.W., Cotman C.W. Basic FGF in adult rat brain: cellular distribution and response to entorhinal lesion and fimbria-fornix transection. J. Neurosci. 12:1992;345-355
17. Hatten M.E., Liem R.K., Shelanski M.L., Mason C.A. Astroglia in CNS injury. Glia. 4:1991;233-243
18. Herrmann O., Tarabin V., Suzuki S., Attigah N., Coserea I., Schneider A., Vogel J., Prinz S., Schwab S., Monyer H., Brombacher F., Schwaninger M. Regulation of body temperature and neuroprotection by endogenous interleukin-6 in cerebral ischemia. J. Cereb. Blood Flow Metab. 23:2003;406-415
19. Jiang N., Finklestein S.P., Do T., Caday C.G., Charette M., Chopp M. Delayed intravenous administration of basic fibroblast growth factor (bFGF) reduces infarct volume in a model of focal cerebral ischemia/reperfusion in the rat. J. Neurol. Sci. 139:1996;173-179
20. Kafitz K.W., Rose C.R., Thoenen H., Konnerth A. Neurotrophin-evoked rapid excitation through TrkB receptors. Nature. 401:1999;918-921
21. Kiprianova I., Sandkuhler J., Schwab S., Hoyer S., Spranger M. Brain-derived neurotrophic factor improves long-term potentiation and cognitive functions after transient forebrain ischemia in the rat. Exp. Neurol. 159:1999;511-519
22. Kirchhoff F., Dringen R., Giaume C. Pathways of neuron-astrocyte interactions and their possible role in neuroprotection. Eur. Arch. Psychiatry Clin. Neurosci. 251:2001;159-169
23. Klein R. Role of neurotrophins in mouse neuronal development. FASEB J. 8:1994;738-744
24. Korte M., Carroll P., Wolf E., Brem G., Thoenen H., Bonhoeffer T. Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor. Proc. Natl. Acad. Sci. U. S. A. 92:1995;8856-8860
25. Lenhard T., Schober A., Suter-Crazzolara C., Unsicker K. Fibroblast growth factor-2 requires glial-cell-line-derived neurotrophic factor for exerting its neuroprotective actions on glutamate-lesioned hippocampal neurons. Mol. Cell. Neurosci. 20:2002;181-197
26. Lin T.N., Te J., Lee M., Sun G.Y., Hsu C.Y. Induction of basic fibroblast growth factor (bFGF) expression following focal cerebral ischemia. Mol. Brain Res. 49:1997;255-265
27. Lindvall O., Ernfors P., Bengzon J., Kokaia Z., Smith M.L., Siesjo B.K., Persson H. Differential regulation of mRNAs for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma. Proc. Natl. Acad. Sci. U. S. A. 89:1992;648-652
28. Linnarsson S., Willson C.A., Ernfors P. Cell death in regenerating populations of neurons in BDNF mutant mice. Mol. Brain Res. 75:2000;61-69
29. Malcangio M., Lessmann V. A common thread for pain and memory synapses? Brain-derived neurotrophic factor and trkB receptors. Trends. Pharmacol. Sci. 24:2003;116-121
30. Mattson M.P., Kumar K.N., Wang H., Cheng B., Michaelis E.K. Basic FGF regulates the expression of a functional 71 kDa NMDA receptor protein that mediates calcium influx and neurotoxicity in hippocampal neurons. J. Neurosci. 13:1993;4575-4588
31. Merlio J.P., Ernfors P., Kokaia Z., Middlemas D.S., Bengzon J., Kokaia M., Smith M.L., Siesjo B.K., Hunter T., Lindvall O. Increased production of the TrkB protein tyrosine kinase receptor after brain insults. Neuron. 10:1993;151-164
32. Morrison R.S., Sharma A., de Vellis J., Bradshaw R.A. Basic fibroblast growth factor supports the survival of cerebral cortical neurons in primary culture. Proc. Natl. Acad. Sci. U. S. A. 83:1986;7537-7541
33. Ortega S., Ittmann M., Tsang S.H., Ehrlich M., Basilico C. Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2. Proc. Natl. Acad. Sci. U. S. A. 95:1998;5672-5677
34. Reilly J.F., Kumari V.G. Alterations in fibroblast growth factor receptor expression following brain injury. Exp. Neurol. 140:1996;139-150
35. Reuss B., von Bohlen und Halbach O. Fibroblast growth factors and their receptors in the central nervous system. Cell. Tissue Res. 313:2003;139-157
36. Reuss B., Dono R., Unsicker K. Functions of fibroblast growth factor (FGF)-2 and FGF-5 in astroglial differentiation and blood-brain barrier permeability: evidence from mouse mutants. J. Neurosci. 23:2003;6404-6412
37. Saarelainen T., Lukkarinen J.A., Koponen S., Grohn O.H., Jolkkonen J., Koponen E., Haapasalo A., Alhonen L., Wong G., Koistinaho J., Kauppinen R.A., Castren E. Transgenic mice overexpressing truncated trkB neurotrophin receptors in neurons show increased susceptibility to cortical injury after focal cerebral ischemia. Mol. Cell. Neurosci. 16:2000;87-96
38. Schäbitz W.R., Schwab S., Spranger M., Hacke W. Intraventricular brain-derived neurotrophic factor reduces infarct size after focal cerebral ischemia in rats. J. Cereb. Blood Flow Metab. 17:1997;500-506
39. Schmidt M.F., Kater S.B. Depolarization and laminin independently enable bFGF to promote neuronal survival through different second messenger pathways. Dev. Biol. 168:1995;235-246
40. Schmidt-Kastner R., Truettner J., Lin B., Zhao W., Saul I., Busto R., Ginsberg M.D. Transient changes of brain-derived neurotrophic factor (BDNF) mRNA expression in hippocampus during moderate ischemia induced by chronic bilateral common carotid artery occlusions in the rat. Mol. Brain Res. 92:2001;157-166
41. Schneider A., Martin-Villalba A., Weih F., Vogel J., Wirth T., Schwaninger M. NF-kappaB is activated and promotes cell death in focal cerebral ischemia. Nat. Med. 5:1999;554-559
42. Shitaka Y., Matsuki N., Saito H., Katsuki H. Basic fibroblast growth factor increases functional L-type Ca2+ channels in fetal rat hippocampal neurons: implications for neurite morphogenesis in vitro. J. Neurosci. 16:1996;6476-6489
43. Sugimori H., Speller H., Finklestein S.P. Intravenous basic fibroblast growth factor produces a persistent reduction in infarct volume following permanent focal ischemia in rats. Neurosci. Lett. 300:2001;13-16
44. Suter-Crazzolara C., Unsicker K. GDNF mRNA levels are induced by FGF-2 in rat C6 glioblastoma cells. Mol. Brain Res. 41:1996;175-182
45. Swanson R.A., Morton M.T., Tsao-Wu G., Savalos R.A., Davidson C., Sharp F.R. A semiautomated method for measuring brain infarct volume. J. Cereb. Blood Flow Metab. 10:1990;290-293
46. Takami K., Iwane M., Kiyota Y., Miyamoto M., Tsukuda R., Shiosaka S. Increase of basic fibroblast growth factor immunoreactivity and its mRNA level in rat brain following transient forebrain ischemia. Exp. Brain Res. 90:1992;1-10
47. Takami K., Kiyota Y., Iwane M., Miyamoto M., Tsukuda R., Igarashi K., Shino A., Wanaka A., Shiosaka S., Tohyama M. Upregulation of fibroblast growth factor-receptor messenger RNA expression in rat brain following transient forebrain ischemia. Exp. Brain Res. 97:1993;185-194
48. Unsicker K., Reichert-Preibsch H., Schmidt R., Pettmann B., Labourdette G., Sensenbrenner M. Astroglial and fibroblast growth factors have neurotrophic functions for cultured peripheral and central nervous system neurons. Proc. Natl. Acad. Sci. U. S. A. 84:1987;5459-5463
49. Vescovi A.L., Reynolds B.A., Fraser D.D., Weiss S. bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells. Neuron. 11:1993;951-966
50. Vogel J., Mobius C., Kuschinsky W. Early delineation of ischemic tissue in rat brain cryosections by high-contrast staining. Stroke. 30:1999;1134-1141
51. von Bohlen und Halbach O., Albrecht D., Heinemann U., Schuchmann S. Spatial nitric oxide imaging using 1,2-diaminoanthraquinone to investigate the involvement of nitric oxide in long-term potentiation in rat brain slices. Neuroimage. 15:2002;633-639
52. Walicke P., Cowan W.M., Ueno N., Baird A., Guillemin R. Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neurite extension. Proc. Natl. Acad. Sci. U. S. A. 83:1986;3012-3016
53. Wei O.Y., Huang Y.L., Da C.D., Cheng J.S. Alteration of basic fibroblast growth factor expression in rat during cerebral ischemia. Acta Pharmacol. Sin. 21:2000;296-300
54. Williams E.J., Furness J., Walsh F.S., Doherty P. Characterisation of the second messenger pathway underlying neurite outgrowth stimulated by FGF. Development. 120:1994;1685-1693
55. Wu D., Pardridge W.M. Neuroprotection with noninvasive neurotrophin delivery to the brain. Proc. Natl. Acad. Sci. U. S. A. 96:1999;254-259
56. Yazaki N., Hosoi Y., Kawabata K., Miyake A., Minami M., Satoh M., Ohta M., Kawasaki T., Itoh N. Differential expression patterns of mRNAs for members of the fibroblast growth factor receptor family, FGFR-1-FGFR-4, in rat brain. J. Neurosci. Res. 37:1994;445-452
57. Yoshida K., Gage F.H. Fibroblast growth factors stimulate nerve growth factor synthesis and secretion by astrocytes. Brain Res. 538:1991;118-126
58. Yoshimura S., Teramoto T., Whalen M.J., Irizarry M.C., Takagi Y., Qiu J., Harada J., Waeber C., Breakefield X.O., Moskowitz M.A. FGF-2 regulates neurogenesis and degeneration in the dentate gyrus after traumatic brain injury in mice. J. Clin. Invest. 112:2003;1202-1210
59. Zhou M., Sutliff R.L., Paul R.J., Lorenz J.N., Hoying J.B., Haudenschild C.C., Yin M., Coffin J.D., Kong L., Kranias E.G., Luo W., Boivin G.P., Duffy J.J., Pawlowski S.A., Doetschman T. Fibroblast growth factor 2 control of vascular tone. Nat. Med. 4:1998;201-207