A new model of primary human adipocytes reveals reduced early insulin signalling in type 2 diabetes

Hormone and Metabolic Research

Volumn 36, Issue 8, 2004, Pages 531-537

  Algenstaedt, P ^a   Rosenblatt, N ^a   Kolb, I ^a   Krutzelmann A ^a   Schwarzloh, B ^a   Bottcher A ^a   Wiesner, L ^a   Greten, H ^a   Hansen Algenstaedt, N ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Human diabetic model; Insulin action; Insulin resistance; Long term insulin treatment; Primary cell culture

Indexed keywords

INSULIN; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN P85;

ADIPOCYTE; ADIPOSE TISSUE; ADULT; AGED; ARTICLE; CELL DIFFERENTIATION; CELL ISOLATION; CONTROLLED STUDY; FEMALE; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERINSULINEMIA; IMMUNOPRECIPITATION; MALE; MODEL; NON INSULIN DEPENDENT DIABETES MELLITUS; ORTHOPEDIC SURGERY; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADIPOCYTES; AGED; CASE-CONTROL STUDIES; CELL DIFFERENTIATION; CELLS, CULTURED; DEOXYGLUCOSE; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; HYPERINSULINISM; INSULIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 4544262908     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-825798     Document Type: Article

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